leucine has been researched along with Disease Exacerbation in 40 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (2.50) | 18.2507 |
| 2000's | 15 (37.50) | 29.6817 |
| 2010's | 19 (47.50) | 24.3611 |
| 2020's | 5 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, J; Guan, J; Guan, Y; Liu, Y; Ou, Y; Wang, D; Xu, C; Yang, W | 1 |
| Abreu, P; Baniecki, M; Bao, W; Damle, B; Gardner, A; Hammond, J; Hendrick, VM; Leister-Tebbe, H; Pypstra, R; Rusnak, JM; Simón-Campos, A; Wisemandle, W | 1 |
| Ang, K; Gurung, RL; Lee, J; Lim, SC; Liu, JJ; Liu, S; Pek, SLT; Shao, YM; Sum, CF; Tang, WE; Tavintharan, S; Wang, J | 1 |
| Augustin, M; Karolyi, M; Kauer, V; Nägeli, M; Totschnig, D; Waldenberger, F; Wenisch, C; Zoufaly, A | 1 |
| Anastácio, LR; Dos Santos, ALS | 1 |
| Amagai, T; Haji, S; Kitagawa, M | 1 |
| Kishida, D; Miyazaki, D; Sato, M; Sekijima, Y | 1 |
| Bregy, L; Bruderer, T; Eiffert, L; Engler, A; Gaugg, MT; Kohler, M; Nussbaumer-Ochsner, Y; Sinues, P; Zenobi, R | 1 |
| Fang, S; He, H; Hua, Y; Huang, Y; Li, R; Liang, S; Liu, P; Tian, Y; Xu, F; Yang, X; Yuan, Y; Zhang, Z | 1 |
| Blum, G; Bogyo, M; Moin, K; Mullins, SR; Sameni, M; Sloane, BF | 1 |
| Hashemi, M; Heidari, Z; Mahmoudzadeh-Sagheb, H; Rigi-Ladiz, MA | 1 |
| Bitu, CC; Bufalino, A; Coletta, RD; Kauppila, JH; Keinänen, M; Lehenkari, P; Nurmenniemi, S; Nyberg, P; Salo, T; Teppo, S; Vilen, ST | 1 |
| Berman, DE; Leibel, RL; Morabito, MV; Schneider, RT; Small, SA; Zhang, Y | 1 |
| Alkhalaf, A; Bakker, SJ; Bilo, HJ; De Heer, E; Gans, RO; Groenier, KH; Kleefstra, N; Landman, GW; Mooyaart, AL; Navis, GJ; van Hateren, KJ | 1 |
| Li, Z; Ni, GX; Zhou, YZ | 1 |
| Chen, WY; Hankinson, SE; Holmes, MD; Tamimi, RM; Wang, J | 1 |
| Becker, AK; Bogyo, M; Gajda, M; Peters, C; Reinheckel, T; Schurigt, U; Schwinde, A; Sevenich, L; Stahl, A; Vannier, C; von Elverfeldt, D; Werner, F | 1 |
| Brábek, J; Folk, P; Mierke, CT; Panková, D; Rösel, D; Tolde, O; Vesely, P | 1 |
| Cruysberg, JR; Das, AM; Engelke, UF; Graham, A; Hogg, SL; Illsinger, S; Kluijtmans, LA; Kremer, BH; Loupatty, FJ; Morava, E; Wanders, RJ; Wevers, RA; Wilcken, B; Willemsen, MA; Wortmann, SB | 1 |
| Imai, H; Kitagawa, W; Komatsuda, A; Miura, N; Nishikawa, K; Suzuki, K; Suzuki, S; Watanabe, D | 1 |
| Iozzo, RV; Schaefer, L | 1 |
| Brown, S; Caterson, B; Eisenstein, SM; Melrose, J; Roberts, S; Roughley, P | 1 |
| Bitla, AR; Kumar, MA; Kumar, VS; Manohar, SM; Narasimha, SR; Raju, KV | 1 |
| Baldzizhar, R; Czyzyk, J; Fedorchuk, C; Henegariu, O; Jha, M; Rathinam, C | 1 |
| Baldari, S; Di Bella, G; Di Leo, R; Gentile, L; Mazzeo, A; Minutoli, F; Russo, M; Stancanelli, C; Vita, G | 1 |
| Chakravarti, S; Kliewer, EV; Murphy, LC; Njue, C; Parisien, M; Roskelley, C; Roughley, PJ; Troup, S; Watson, PH | 1 |
| Awazu, M; Fujita, H; Hida, M; Ishikura, K; Omori, S | 1 |
| Arai, H; Doi, T; Fukatsu, A; Iehara, N; Kanamori, H; Kita, T; Matsubara, T; Nagai, K; Nakano, T; Yanagita, M | 1 |
| Bojesen, SE; Nordestgaard, BG; Tybjaerg-Hansen, A | 1 |
| Abrahamsson, PA; Ahlgren, G; Gadaleanu, V; Giwercman, A; Giwercman, YL | 1 |
| Keilhauer, CN; Meigen, T; Weber, BH | 1 |
| Baccarani, M; Bosi, C; Castagnetti, F; Cilloni, D; Colarossi, S; Giannoulia, P; Gnani, A; Iacobucci, I; Luatti, S; Martinelli, G; Marzocchi, G; Palandri, F; Paolini, S; Piccaluga, PP; Rondoni, M; Rosti, G; Saglio, G; Soverini, S; Testoni, N | 1 |
| Ino, K; Kajiyama, H; Kikkawa, F; Mizutani, S; Nawa, A; Shibata, K; Terauchi, M | 1 |
| Chandoga, J; Petrovic, R; Sutovský, S; Turcáni, P | 1 |
| Kajiyama, H; Kikkawa, F; Nawa, A; Shibata, K; Terauchi, M; Tsukamoto, H | 1 |
| Baumgartner, ER; Pfenninger, J; Suormala, T; Wiesmann, UN | 1 |
| Bogyo, M; Burlingame, A; Greenbaum, D; Medzihradszky, KF | 1 |
| Chu, W; Harvie, S; Ho, M; Jewett, MA; Nam, RK; Narod, SA; Sweet, J; Toi, A; Trachtenberg, J; Vesprini, D | 1 |
| Platz, EA | 1 |
| Karvonen, MK; Kauhanen, J; Koulu, M; Lakka, HM; Lakka, TA; Nyyssönen, K; Pesonen, U; Salonen, JT; Salonen, R; Tuomainen, TP; Uusitupa, MI; Valkonen, VP | 1 |
3 review(s) available for leucine and Disease Exacerbation
| Article | Year |
|---|---|
The impact of L-branched-chain amino acids and L-leucine on malnutrition, sarcopenia, and other outcomes in patients with chronic liver disease.
Topics: Administration, Oral; Amino Acids, Branched-Chain; Chronic Disease; Dietary Supplements; Disease Progression; Leucine; Liver Diseases; Malnutrition; Proteolysis; Sarcopenia | 2021 |
The role of small leucine-rich proteoglycans in osteoarthritis pathogenesis.
Topics: Animals; Disease Models, Animal; Disease Progression; Humans; Leucine; Mice; Osteoarthritis; Proteoglycans; Signal Transduction; Transforming Growth Factor beta | 2014 |
Progressive renal failure despite long-term biweekly enzyme replacement therapy in a patient with Fabry disease secondary to a new α-galactosidase mutation of Leu311Arg (L311R).
Topics: Adult; alpha-Galactosidase; Arginine; Biopsy; Disease Progression; DNA Mutational Analysis; Drug Administration Schedule; Enzyme Replacement Therapy; Fabry Disease; Glomerular Filtration Rate; Humans; Isoenzymes; Kidney; Leucine; Male; Mutation; Recombinant Proteins; Renal Insufficiency; Time Factors; Treatment Outcome | 2011 |
1 trial(s) available for leucine and Disease Exacerbation
| Article | Year |
|---|---|
Oral Nirmatrelvir for High-Risk, Nonhospitalized Adults with Covid-19.
Topics: Administration, Oral; Adult; Antiviral Agents; COVID-19 Drug Treatment; Disease Progression; Double-Blind Method; Hospitalization; Humans; Lactams; Leucine; Nitriles; Proline; Ritonavir; SARS-CoV-2; Treatment Outcome; Vaccination; Viral Load; Viral Protease Inhibitors | 2022 |
36 other study(ies) available for leucine and Disease Exacerbation
| Article | Year |
|---|---|
E3 ligase RNF167 and deubiquitinase STAMBPL1 modulate mTOR and cancer progression.
Topics: Animals; Caco-2 Cells; Cell Proliferation; Colorectal Neoplasms; Disease Progression; Gene Expression Regulation, Neoplastic; HCT116 Cells; HEK293 Cells; Humans; Leucine; Mechanistic Target of Rapamycin Complex 1; Mice, Inbred BALB C; Mice, Nude; Mutation; Nuclear Proteins; Peptide Hydrolases; Signal Transduction; Stomach Neoplasms; TOR Serine-Threonine Kinases; Tumor Burden; Ubiquitin-Protein Ligases; Ubiquitination | 2022 |
Urine Leucine-Rich α-2 Glycoprotein 1 (LRG1) Predicts the Risk of Progression to End-Stage Kidney Disease in Patients With Type 2 Diabetes.
Topics: Diabetes Mellitus, Type 2; Disease Progression; Glomerular Filtration Rate; Glycoproteins; Humans; Kidney Failure, Chronic; Leucine; Transforming Growth Factor beta | 2023 |
Efficacy of Sotrovimab (SOT), Molnupiravir (MOL), and Nirmatrelvir/Ritponavir (N/R) and Tolerability of Molnupiravir in Outpatients at High Risk for Severe COVID-19.
Topics: Antiviral Agents; COVID-19; Disease Progression; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Lactams; Leucine; Outpatients; Retrospective Studies | 2023 |
High Serum Essential Amino Acids as a Predictor of Skeletal Muscle Depletion in Patients With Cachexia and Advanced Gastrointestinal Cancers.
Topics: Aged; Amino Acids, Essential; Antineoplastic Agents; Biomarkers; C-Reactive Protein; Cachexia; Disease Progression; Female; Gastrointestinal Neoplasms; Humans; Isoleucine; Japan; Leucine; Male; Medical Records; Neoplasm Staging; Psoas Muscles; Retrospective Studies; Risk; Sarcopenia; Tomography, X-Ray Computed; Up-Regulation | 2017 |
A Patient with Limbic Encephalitis Associated with Anti-leucine-rich Glioma-inactivated 1 (LGI1) Antibody Presenting with Slowly Progressive Cognitive Impairment and Fluctuating Striatal Lesions.
Topics: Administration, Intravenous; Anti-Inflammatory Agents; Autoantibodies; Brain; Cognitive Dysfunction; Dementia; Diagnosis, Differential; Disease Progression; Humans; Intracellular Signaling Peptides and Proteins; Leucine; Limbic Encephalitis; Magnetic Resonance Imaging; Male; Methylprednisolone; Middle Aged; Prednisolone; Proteins; Seizures | 2019 |
Molecular breath analysis supports altered amino acid metabolism in idiopathic pulmonary fibrosis.
Topics: Aged; Alanine; Amino Acids; Area Under Curve; Biomarkers; Breath Tests; Case-Control Studies; Disease Progression; Exhalation; Female; Humans; Hydroxyproline; Idiopathic Pulmonary Fibrosis; Isoleucine; Leucine; Male; Middle Aged; ROC Curve; Spectrometry, Mass, Electrospray Ionization; Valine | 2019 |
Time Series Characteristics of Serum Branched-Chain Amino Acids for Early Diagnosis of Chronic Heart Failure.
Topics: Animals; Area Under Curve; Biomarkers; Disease Models, Animal; Disease Progression; Early Diagnosis; Heart Failure; Leucine; Machine Learning; Male; Metabolome; Metabolomics; Myocardial Infarction; Rats; Rats, Sprague-Dawley; ROC Curve; Valine | 2019 |
Three-dimensional cultures modeling premalignant progression of human breast epithelial cells: role of cysteine cathepsins.
Topics: Apoptosis; Breast; Breast Neoplasms; Cathepsin B; Cathepsin L; Cell Culture Techniques; Cell Line, Tumor; Cell Survival; Cell Transformation, Neoplastic; Cysteine Proteinase Inhibitors; Dipeptides; Disease Progression; Epithelial Cells; Female; Humans; Leucine; Models, Biological | 2012 |
Quantitative analysis of interdental Gingiva in patients with chronic periodontitis and transforming growth factor-β1 29C/T gene polymorphisms.
Topics: Adult; Alleles; Azo Compounds; Case-Control Studies; Chronic Periodontitis; Collagen; Coloring Agents; Connective Tissue; Cytosine; Disease Progression; Eosine Yellowish-(YS); Epithelium; Extracellular Matrix; Female; Genotype; Gingiva; Humans; Leucine; Male; Methyl Green; Microvessels; Middle Aged; Polymorphism, Genetic; Proline; Thymine; Transforming Growth Factor beta1 | 2014 |
Cathepsin K is present in invasive oral tongue squamous cell carcinoma in vivo and in vitro.
Topics: Aged; Blotting, Western; Carcinoma, Squamous Cell; Cathepsin K; Cell Line, Tumor; Cells, Cultured; Cysteine Proteinase Inhibitors; Disease Progression; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Leucine; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Organ Culture Techniques; Prognosis; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Tongue Neoplasms; Tumor Microenvironment | 2013 |
Hyperleucinemia causes hippocampal retromer deficiency linking diabetes to Alzheimer's disease.
Topics: Alzheimer Disease; Analysis of Variance; Animals; Cell Line, Tumor; Diabetes Mellitus, Type 2; Disease Progression; Enzyme-Linked Immunosorbent Assay; Glucose Tolerance Test; Hippocampus; Humans; Leptin; Leucine; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuroblastoma; Vesicular Transport Proteins | 2014 |
Sex specific association between carnosinase gene CNDP1 and cardiovascular mortality in patients with type 2 diabetes (ZODIAC-22).
Topics: Aged; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dipeptidases; Disease Progression; Female; Follow-Up Studies; Glomerular Filtration Rate; Homozygote; Humans; Leucine; Male; Middle Aged; Polymorphism, Genetic; Proportional Hazards Models; Prospective Studies; Sex Factors | 2015 |
Protein Intake and Breast Cancer Survival in the Nurses' Health Study.
Topics: Adult; Amino Acids, Branched-Chain; Amino Acids, Essential; Breast Neoplasms; Dietary Proteins; Disease Progression; Energy Metabolism; Female; Humans; Kaplan-Meier Estimate; Leucine; Middle Aged; Multivariate Analysis; Neoplasm Metastasis; Neoplasm Staging; Nurses; Nutritional Status; Odds Ratio; Proportional Hazards Models; Prospective Studies; Protective Factors; Recommended Dietary Allowances; Risk Assessment; Risk Factors; Time Factors; United States | 2017 |
Trial of the cysteine cathepsin inhibitor JPM-OEt on early and advanced mammary cancer stages in the MMTV-PyMT-transgenic mouse model.
Topics: Animals; Breast Neoplasms; Cathepsins; Cysteine Proteinase Inhibitors; Disease Models, Animal; Disease Progression; Female; Leucine; Magnetic Resonance Imaging; Mammary Tumor Virus, Mouse; Mice; Mice, Transgenic; Neoplasm Staging | 2008 |
Neoplastic progression of the human breast cancer cell line G3S1 is associated with elevation of cytoskeletal dynamics and upregulation of MT1-MMP.
Topics: Actins; Aprotinin; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cytoskeleton; Dipeptides; Disease Progression; Female; Gelatin; Humans; Leucine; Marine Toxins; Matrix Metalloproteinase 14; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases, Secreted; Neoplasm Invasiveness; Neoplastic Stem Cells; Protease Inhibitors; Pseudopodia; Up-Regulation | 2010 |
3-Methylglutaconic aciduria type I redefined: a syndrome with late-onset leukoencephalopathy.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Brain; Brain Diseases, Metabolic, Inborn; Brain Mapping; Child; Disease Progression; Female; Glutarates; Humans; Image Processing, Computer-Assisted; Infant; Leucine; Leukoencephalopathies; Magnetic Resonance Imaging; Male; Middle Aged; Nerve Fibers, Myelinated | 2010 |
Small leucine-rich proteoglycans, at the crossroad of cancer growth and inflammation.
Topics: Disease Progression; Humans; Inflammation; Leucine; Neoplasms; Proteoglycans | 2012 |
A comparative evaluation of the small leucine-rich proteoglycans of pathological human intervertebral discs.
Topics: Adult; Biglycan; Chondroitin Sulfate Proteoglycans; Cohort Studies; Decorin; Disease Progression; Extracellular Matrix Proteins; Female; Fibromodulin; Humans; Intervertebral Disc; Intervertebral Disc Degeneration; Intervertebral Disc Displacement; Keratan Sulfate; Leucine; Lumican; Male; Middle Aged; Proteoglycans; Scoliosis | 2012 |
Branched chain amino acid profile in early chronic kidney disease.
Topics: Adult; Amino Acids, Branched-Chain; Biomarkers; C-Reactive Protein; Case-Control Studies; Disease Progression; Humans; Hypoalbuminemia; India; Inflammation Mediators; Leucine; Malnutrition; Middle Aged; Nutritional Status; Renal Insufficiency, Chronic; Serum Albumin; Valine | 2012 |
Anti-serpin antibody-mediated regulation of proteases in autoimmune diabetes.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Neutralizing; Antigens, CD19; Autoantibodies; CD4 Antigens; Cysteine Proteinase Inhibitors; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Progression; Female; Gene Expression; Immunity, Humoral; Interferon-gamma; Islets of Langerhans; Leucine; Lymph Nodes; Mice; Mice, Inbred NOD; Serpins; T-Lymphocytes | 2013 |
Transthyretin-related familial amyloidotic polyneuropathy: description of a cohort of patients with Leu64 mutation and late onset.
Topics: Age of Onset; Aged; Aged, 80 and over; Amyloid Neuropathies, Familial; Autonomic Nervous System Diseases; Biopsy; Cohort Studies; Diphosphonates; Disease Progression; Electromyography; Female; Follow-Up Studies; Hereditary Sensory and Motor Neuropathy; Humans; Leucine; Male; Middle Aged; Muscle Weakness; Mutation; Neurologic Examination; Organotechnetium Compounds; Phenotype; Prealbumin; Radionuclide Imaging; Radiopharmaceuticals | 2012 |
Reduced expression of the small leucine-rich proteoglycans, lumican, and decorin is associated with poor outcome in node-negative invasive breast cancer.
Topics: Blotting, Western; Breast Neoplasms; Chondroitin Sulfate Proteoglycans; Decorin; Disease Progression; Disease-Free Survival; Electrophoresis, Polyacrylamide Gel; Extracellular Matrix Proteins; Female; Humans; Immunoblotting; Keratan Sulfate; Leucine; Lumican; Lymph Nodes; Prognosis; Proteoglycans; Time Factors; Treatment Outcome | 2003 |
The lack of cyclin kinase inhibitor p27(Kip1) ameliorates progression of diabetic nephropathy.
Topics: Adaptor Proteins, Signal Transducing; Albuminuria; Animals; Blood Group Antigens; Carrier Proteins; Cell Cycle Proteins; Cyclin-Dependent Kinase Inhibitor p27; Diabetic Nephropathies; Disease Progression; Eukaryotic Initiation Factors; Fibronectins; Glomerular Mesangium; Hyperglycemia; Leucine; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Phosphoproteins; Phosphorylation; Proliferating Cell Nuclear Antigen; Thymidine; Transforming Growth Factor beta; Tritium; Tumor Suppressor Proteins | 2003 |
Growth arrest-specific gene 6 is involved in glomerular hypertrophy in the early stage of diabetic nephropathy.
Topics: Albuminuria; Animals; Axl Receptor Tyrosine Kinase; Blotting, Western; Diabetic Nephropathies; Disease Progression; Flow Cytometry; Glomerular Filtration Rate; Humans; Hypertrophy; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Kidney; Kidney Diseases; Leucine; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Oncogene Proteins; Proteins; Proto-Oncogene Proteins; Rats; Receptor Protein-Tyrosine Kinases; Recombinant Proteins; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1; Warfarin | 2003 |
Integrin beta3 Leu33Pro homozygosity and risk of cancer.
Topics: Adult; Aged; Aged, 80 and over; Alleles; Animals; Cytosine; Denmark; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Genotype; Humans; Incidence; Integrin beta3; Leucine; Male; Middle Aged; Neoplasm Invasiveness; Neoplasms; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Proline; Proportional Hazards Models; Prospective Studies; Registries; Risk Assessment; Risk Factors; Thymine | 2003 |
The 5alpha-reductase type II A49T and V89L high-activity allelic variants are more common in men with prostate cancer compared with the general population.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Aged; Alanine; Alleles; Arginine; Biomarkers, Tumor; Case-Control Studies; Dihydrotestosterone; Disease Progression; Follow-Up Studies; Genetic Predisposition to Disease; Genotype; Glutamine; Humans; Leucine; Luteinizing Hormone; Male; Middle Aged; Point Mutation; Polymorphism, Genetic; Prostatic Hyperplasia; Prostatic Neoplasms; Receptors, Androgen; Risk Factors; Sex Hormone-Binding Globulin; Sweden; Terminal Repeat Sequences; Testosterone; Threonine; Valine | 2005 |
Clinical findings in a multigeneration family with autosomal dominant central areolar choroidal dystrophy associated with an Arg195Leu mutation in the peripherin/RDS gene.
Topics: Adolescent; Adult; Age of Onset; Arginine; Choroid Diseases; Codon; Disease Progression; DNA Mutational Analysis; Electroretinography; Female; Fluorescein Angiography; Genes, Dominant; Humans; Intermediate Filament Proteins; Leucine; Male; Membrane Glycoproteins; Nerve Tissue Proteins; Pedigree; Peripherins; Point Mutation; Visual Acuity | 2006 |
Presence or the emergence of a F317L BCR-ABL mutation may be associated with resistance to dasatinib in Philadelphia chromosome-positive leukemia.
Topics: Adult; Antineoplastic Agents; Blast Crisis; Clinical Trials, Phase II as Topic; Dasatinib; Disease Progression; Drug Resistance, Neoplasm; Female; Genes, abl; Humans; Leucine; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Mutation; Phenylalanine; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase Inhibitors; Pyrimidines; Thiazoles; Treatment Failure | 2006 |
Inhibition of APN/CD13 leads to suppressed progressive potential in ovarian carcinoma cells.
Topics: Animals; CD13 Antigens; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; Female; Humans; Leucine; Matrix Metalloproteinase 2; Mice; Mice, Inbred BALB C; Ovarian Neoplasms | 2007 |
Adult onset cerebral form of X-linked adrenoleukodystrophy with dementia of frontal lobe type with new L160P mutation in ABCD1 gene.
Topics: Adrenoleukodystrophy; Adult; ATP Binding Cassette Transporter, Subfamily D, Member 1; ATP-Binding Cassette Transporters; Dementia; Disease Progression; DNA Mutational Analysis; Family Health; Female; Follow-Up Studies; Humans; Leucine; Magnetic Resonance Imaging; Male; Mutation; Proline | 2007 |
Aminopeptidase N (APN)/CD13 inhibitor, Ubenimex, enhances radiation sensitivity in human cervical cancer.
Topics: Animals; CD13 Antigens; Disease Progression; Female; HeLa Cells; Humans; In Situ Nick-End Labeling; Leucine; Mice; Mice, Nude; Neoplasm Transplantation; Protease Inhibitors; Radiation Tolerance; Radiotherapy; Uterine Cervical Neoplasms | 2008 |
Partial 3-methylcrotonyl-CoA carboxylase deficiency in an infant with fatal outcome due to progressive respiratory failure.
Topics: Brain; Carbon-Carbon Ligases; Disease Progression; Fatal Outcome; Humans; Infant; Leucine; Male; Metabolism, Inborn Errors; Respiratory Insufficiency | 1998 |
Epoxide electrophiles as activity-dependent cysteine protease profiling and discovery tools.
Topics: Affinity Labels; Animals; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dendritic Cells; Disease Progression; Epoxy Compounds; Gene Expression Regulation, Enzymologic; Kidney; Leucine; Mice; Molecular Probes; Neoplasm Proteins; Organ Specificity; Peptide Library; Peptides; Rats; Skin Neoplasms; Substrate Specificity; Tumor Cells, Cultured | 2000 |
V89L polymorphism of type-2, 5-alpha reductase enzyme gene predicts prostate cancer presence and progression.
Topics: Aged; Alleles; Cholestenone 5 alpha-Reductase; Disease Progression; Follow-Up Studies; Genetic Markers; Humans; Leucine; Male; Middle Aged; Neoplasm Proteins; Neoplasm Recurrence, Local; Odds Ratio; Oxidoreductases; Phenotype; Polymorphism, Genetic; Prostatic Neoplasms; Valine | 2001 |
Basic Science.
Topics: Cholestenone 5 alpha-Reductase; Disease Progression; Genotype; Humans; Leucine; Male; Neoplasm Proteins; Neoplasm Recurrence, Local; Oxidoreductases; Polymorphism, Genetic; Prostate-Specific Antigen; Valine | 2001 |
Leucine7 to proline7 polymorphism in the preproneuropeptide Y is associated with the progression of carotid atherosclerosis, blood pressure and serum lipids in Finnish men.
Topics: Adult; Blood Pressure; Carotid Artery Diseases; Disease Progression; Finland; Humans; Leucine; Lipids; Male; Middle Aged; Neuropeptide Y; Polymorphism, Genetic; Proline; Protein Precursors; Risk Factors | 2001 |