leucine has been researched along with Diabetic Glomerulosclerosis in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 12 (54.55) | 29.6817 |
| 2010's | 4 (18.18) | 24.3611 |
| 2020's | 6 (27.27) | 2.80 |
| Authors | Studies |
|---|---|
| Cai, G; Cai, H; Chen, XM; He, JC; Hong, Q; Lee, K; Li, Z; Ni, Z; Zhang, L; Zhong, F | 1 |
| Bjornstad, P; Cara-Fuentes, G; Cherney, D; Chung, LT; Johnson, RJ; Lanaspa, MA; MacDonald, A; Melena, I; Nadeau, KJ; Nelson, RG; Parikh, CR; Pavkov, ME; Piani, F; Pyle, L; Rewers, A; Roncal-Jimenez, CA; Severn, C; Tommerdahl, KL; van Raalte, DH; Vinovskis, C | 1 |
| He, A; Shen, X; Shi, C; Wan, Y; Wu, X; Yang, J; Zhou, Y; Zhu, X | 1 |
| Altıncık, SA; Avcı, E; Girişgen, İ; Özhan, B; Yıldırımçakar, D; Yüksel, S | 1 |
| Cho, DH; Chung, DJ; Chung, JO; Chung, MY; Park, SY | 1 |
| Fang, ZZ; Gao, X; Hou, R; Li, X; Liu, SL; Luo, HH; Qiu, XH | 1 |
| Alkhalaf, A; Bakker, SJ; Bilo, HJ; De Heer, E; Gans, RO; Groenier, KH; Kleefstra, N; Landman, GW; Mooyaart, AL; Navis, GJ; van Hateren, KJ | 1 |
| Barazzoni, R; Cortella, I; Gabelli, C; Kiwanuka, E; Manesso, E; Pasqualetto, G; Puricelli, L; Tessari, P; Toffolo, GM; Vettore, M; Zanetti, M | 1 |
| Crowley, VE; DeLong, C; Hand, E; Hatunic, M; Nolan, JJ; Stapleton, M | 1 |
| Chen, W; Hang, W; Huang, B; Lin, L; Song, X; Yan, L; Yan, X; Zhang, J | 1 |
| Baelde, HJ; Bakker, SJ; Bilo, HJ; Böhringer, S; Bruijn, JA; De Heer, E; Dekker, FW; Grootendorst, DC; Janssen, B; Kleefstra, N; Mooyaart, AL; Navis, G; van Valkengoed, IG; Zutinic, A | 1 |
| Gao, Y; Liu, XH; Yu, DQ | 1 |
| Awazu, M; Fujita, H; Hida, M; Ishikura, K; Omori, S | 2 |
| Arai, H; Doi, T; Fukatsu, A; Iehara, N; Kanamori, H; Kita, T; Matsubara, T; Nagai, K; Nakano, T; Yanagita, M | 1 |
| Adler, SG; Kim, YS; Lanting, L; Natarajan, R; Reddy, MA | 1 |
| Baelde, H; Bakker, SJ; Bartram, CR; Brinkkoetter, P; Cerna, M; de Heer, E; Fischer, C; Hammes, HP; Hohenadel, D; Janssen, B; Köppel, H; Mathieson, P; Meyer, J; Nawroth, P; Peters, V; Rind, N; Romzova, M; Rondeau, E; Rychlik, I; Saleem, MA; Sauerhoefer, S; van der Woude, FJ; Yard, BA; Zirie, M; Zschocke, J | 1 |
| Bowden, DW; Freedman, BI; Hicks, PJ; Janssen, B; Langefeld, CD; McDonough, C; Pierson, ED; Rich, SS; Sale, MM; van der Woude, FJ; Xu, J; Yard, BA | 1 |
| Batlle, D; Kanwar, Y; Lloveras, J; Soler, MJ; Wysocki, J; Ye, M | 1 |
| Brismar, K; Dahlquist, G; Efendic, S; Falhammar, H; Gu, HF; Ma, J; Möllsten, A; Nordman, S | 1 |
| Castellino, P; Ciarambino, T; Cioffi, M; De Feo, P; Gesuè, L; Giordano, M; Gresele, P; Lucidi, P; Paolisso, G | 1 |
| Choi, HJ; Han, HJ; Kim, JH; Lee, JH; Park, SH; Woo, CH | 1 |
1 trial(s) available for leucine and Diabetic Glomerulosclerosis
| Article | Year |
|---|---|
A leucine repeat in the carnosinase gene CNDP1 is associated with diabetic end-stage renal disease in European Americans.
Topics: Adult; Aged; Alleles; Carnosine; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dipeptidases; Europe; Female; Genetic Linkage; Genetic Predisposition to Disease; Genotype; Humans; Kidney Failure, Chronic; Leucine; Male; Middle Aged; Polymorphism, Single Nucleotide; Risk Factors; Trinucleotide Repeats; United States; White People | 2007 |
21 other study(ies) available for leucine and Diabetic Glomerulosclerosis
| Article | Year |
|---|---|
Modulation of transforming growth factor-β-induced kidney fibrosis by leucine-rich ⍺-2 glycoprotein-1.
Topics: Animals; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Endothelial Cells; Fibrosis; Glycoproteins; Humans; Kidney; Leucine; Mice; Smad3 Protein; Transforming Growth Factor beta; Transforming Growth Factor beta1; Transforming Growth Factors; Ureteral Obstruction | 2022 |
Aminoaciduria and metabolic dysregulation during diabetic ketoacidosis: Results from the diabetic kidney alarm (DKA) study.
Topics: Adolescent; Amino Acids; Child; Creatinine; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Diabetic Nephropathies; Female; Histidine; Humans; Leucine; Male; Threonine; Tryptophan | 2022 |
Urinary metabolites associate with the presence of diabetic kidney disease in type 2 diabetes and mediate the effect of inflammation on kidney complication.
Topics: Biomarkers; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Inflammation; Interleukin-18; Kidney; Leucine | 2023 |
Plasma leucine-rich α-2-glycoprotein 1 - a novel marker of diabetic kidney disease in children and adolescents with type 1 diabetes mellitus?
Topics: Adolescent; Albuminuria; Child; Cystatin C; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Glomerular Filtration Rate; Glycoproteins; Humans; Leucine | 2023 |
Relationship between plasma leucine-rich α-2-glycoprotein 1 and urinary albumin excretion in patients with type 2 diabetes.
Topics: Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Glycoproteins; Humans; Leucine | 2023 |
The Association Between Leucine and Diabetic Nephropathy in Different Gender: A Cross-Sectional Study in Chinese Patients With Type 2 Diabetes.
Topics: Adult; Aged; Biomarkers; China; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Leucine; Male; Middle Aged; Risk Factors; Sex Characteristics | 2020 |
Sex specific association between carnosinase gene CNDP1 and cardiovascular mortality in patients with type 2 diabetes (ZODIAC-22).
Topics: Aged; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dipeptidases; Disease Progression; Female; Follow-Up Studies; Glomerular Filtration Rate; Homozygote; Humans; Leucine; Male; Middle Aged; Polymorphism, Genetic; Proportional Hazards Models; Prospective Studies; Sex Factors | 2015 |
Decreased VLDL-Apo B 100 Fractional Synthesis Rate Despite Hypertriglyceridemia in Subjects With Type 2 Diabetes and Nephropathy.
Topics: Adult; Aged; Apolipoprotein B-100; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Hypertriglyceridemia; Insulin; Kinetics; Leucine; Lipoproteins, VLDL; Male; Middle Aged; Radionuclide Imaging; Radiopharmaceuticals | 2015 |
The Leu262Val polymorphism of presenilin associated rhomboid like protein (PARL) is associated with earlier onset of type 2 diabetes and increased urinary microalbumin creatinine ratio in an Irish case-control population.
Topics: Age of Onset; Albuminuria; Amino Acid Substitution; Animals; Case-Control Studies; Creatinine; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Disease Models, Animal; Genetic Variation; Gerbillinae; Humans; Hyperinsulinism; Ireland; Leucine; Metalloproteases; Mitochondrial Proteins; Polymorphism, Single Nucleotide; Reference Values; Valine | 2009 |
Metabonomics research of diabetic nephropathy and type 2 diabetes mellitus based on UPLC-oaTOF-MS system.
Topics: Adult; Aged; Biomarkers; Chromatography, High Pressure Liquid; Cluster Analysis; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Leucine; Male; Metabolome; Metabolomics; Middle Aged; Principal Component Analysis; Spectrometry, Mass, Electrospray Ionization; Sphingosine | 2009 |
Association between CNDP1 genotype and diabetic nephropathy is sex specific.
Topics: Age of Onset; Aged; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dipeptidases; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homozygote; Humans; Leucine; Male; Middle Aged; Reference Values; Repetitive Sequences, Amino Acid; Sex Characteristics; White People | 2010 |
[Effects of Rhein on the hypertrophy of renal proximal tubular epithelial cells induced by high glucose and angiotensin II in rats].
Topics: Angiotensin II; Animals; Anthraquinones; Cells, Cultured; Diabetic Nephropathies; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Epithelial Cells; Glucose; Hypertrophy; Kidney Tubules, Proximal; Leucine; Proteins; Random Allocation; Rats; Rats, Sprague-Dawley; Rheum | 2010 |
The lack of cyclin kinase inhibitor p27(Kip1) ameliorates progression of diabetic nephropathy.
Topics: Adaptor Proteins, Signal Transducing; Albuminuria; Animals; Blood Group Antigens; Carrier Proteins; Cell Cycle Proteins; Cyclin-Dependent Kinase Inhibitor p27; Diabetic Nephropathies; Disease Progression; Eukaryotic Initiation Factors; Fibronectins; Glomerular Mesangium; Hyperglycemia; Leucine; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Phosphoproteins; Phosphorylation; Proliferating Cell Nuclear Antigen; Thymidine; Transforming Growth Factor beta; Tritium; Tumor Suppressor Proteins | 2003 |
Growth arrest-specific gene 6 is involved in glomerular hypertrophy in the early stage of diabetic nephropathy.
Topics: Albuminuria; Animals; Axl Receptor Tyrosine Kinase; Blotting, Western; Diabetic Nephropathies; Disease Progression; Flow Cytometry; Glomerular Filtration Rate; Humans; Hypertrophy; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Kidney; Kidney Diseases; Leucine; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Oncogene Proteins; Proteins; Proto-Oncogene Proteins; Rats; Receptor Protein-Tyrosine Kinases; Recombinant Proteins; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1; Warfarin | 2003 |
ERK and p38 mediate high-glucose-induced hypertrophy and TGF-beta expression in renal tubular cells.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enzyme Activation; Glucose; Hypertrophy; Hypoglycemic Agents; Immunohistochemistry; Insulin; Kidney Tubules, Proximal; Leucine; LLC-PK1 Cells; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Rats, Sprague-Dawley; Swine; Transforming Growth Factor beta; Tritium | 2004 |
Differential behavior of mesangial cells derived from 12/15-lipoxygenase knockout mice relative to control mice.
Topics: Animals; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Cell Division; Cell Line; Cyclic AMP Response Element-Binding Protein; Diabetic Nephropathies; Fibronectins; Gene Expression Regulation, Enzymologic; Genes, Immediate-Early; Glomerular Mesangium; Leucine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinases; Oxidative Stress; Phosphorylation; Proto-Oncogene Proteins c-fos; Sp1 Transcription Factor; Superoxides; Thymidine; Tritium | 2003 |
Carnosine as a protective factor in diabetic nephropathy: association with a leucine repeat of the carnosinase gene CNDP1.
Topics: Aged; Carnosine; Cells, Cultured; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dipeptidases; Female; Gene Expression; Genetic Predisposition to Disease; Glucose; Humans; Kidney; Leucine; Male; Middle Aged; Repetitive Sequences, Amino Acid; RNA, Messenger; Sequence Alignment | 2005 |
ACE2 inhibition worsens glomerular injury in association with increased ACE expression in streptozotocin-induced diabetic mice.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Imidazoles; Kidney Glomerulus; Leucine; Mice; Peptidyl-Dipeptidase A; Streptozocin; Up-Regulation | 2007 |
Distribution of neuropeptide Y Leu7Pro polymorphism in patients with type 1 diabetes and diabetic nephropathy among Swedish and American populations.
Topics: Adult; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Leucine; Male; Middle Aged; Neuropeptide Y; Polymorphism, Single Nucleotide; Proline; Sweden; United States | 2007 |
Effects of dietary protein restriction on albumin and fibrinogen synthesis in macroalbuminuric type 2 diabetic patients.
Topics: Adult; Albumins; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diet, Protein-Restricted; Dietary Proteins; Female; Fibrinogen; Humans; Leucine; Male; Middle Aged; Proteinuria; Treatment Outcome | 2008 |
High glucose inhibits renal proximal tubule cell proliferation and involves PKC, oxidative stress, and TGF-beta 1.
Topics: Acetylcysteine; Animals; Antioxidants; Cell Cycle; Cell Division; Cells, Cultured; Diabetic Nephropathies; Glucose; Kidney Tubules, Proximal; Leucine; Lipid Peroxides; Oxidative Stress; Protein Kinase C; Rabbits; Taurine; Thymidine; Transforming Growth Factor beta; Vitamin E | 2001 |