leucine and Diabetes Mellitus, Type 1

leucine has been researched along with Diabetes Mellitus, Type 1 in 70 studies

Research

Studies (70)

Timeframe	Studies, this research(%)	All Research%
pre-1990	19 (27.14)	18.7374
1990's	24 (34.29)	18.2507
2000's	16 (22.86)	29.6817
2010's	8 (11.43)	24.3611
2020's	3 (4.29)	2.80

Authors

Authors	Studies
Bjornstad, P; Cara-Fuentes, G; Cherney, D; Chung, LT; Johnson, RJ; Lanaspa, MA; MacDonald, A; Melena, I; Nadeau, KJ; Nelson, RG; Parikh, CR; Pavkov, ME; Piani, F; Pyle, L; Rewers, A; Roncal-Jimenez, CA; Severn, C; Tommerdahl, KL; van Raalte, DH; Vinovskis, C	1
Al-Sari, NH; Legido-Quigley, C; Mattila, IM; Pedersen, J; Pedersen-Bjergaard, U; Sejling, AS; She, R	1
Altıncık, SA; Avcı, E; Girişgen, İ; Özhan, B; Yıldırımçakar, D; Yüksel, S	1
Coqueiro, AY; Lima, VBS; Martins, CEC; Ribeiro, HQT; Tirapegui, J	1
Bruttomesso, D; Tessari, P	1
Couch, SC; Crandell, JL; Jaacks, LM; Lamichhane, AP; Lawrence, JM; Mayer-Davis, EJ	1
Battezzati, A; Benedini, S; DeTaddeo, F; Luzi, L; Maffi, P; Secchi, A; Sereni, LP	1
Boirie, Y; Crombach, N; Fauquant, J; Gijsen, AP; Kies, AK; Koopman, R; Lemosquet, S; Saris, WH; van Loon, LJ; Walrand, S	1
Ando, T; Endo, F; Matsumoto, S; Mochida, T; Nakamura, K; Okamoto, M; Shimbo, K; Shiraki, Y; Tajiri, H; Tanaka, T	1
Beck, A; Boehm, BO; Brücken, R; Burster, T; Kalbacher, H; Palesch, D; Schäfer, N; Sienczyk, M; Sun, Z; Zou, F	1
Bonner, C; Byrne, MM; Farrelly, AM; Kilbride, SM; Prehn, JH	1
Adegoke, OA; Gordon, CS; Hawke, TJ; Riddell, MC; Serino, AS; Szigiato, AA; Zargar, S	1
Baldzizhar, R; Czyzyk, J; Fedorchuk, C; Henegariu, O; Jha, M; Rathinam, C	1
GOSCINSKA, Z; GUMINSKA, M; HALIKOWSKI, B	2
BECK, JC; GONDA, A; HAMID, MA; MCGARRY, EE; MORGEN, RO; RUBINSTEIN, D	1
KELLEY, VC; RUVALCABA, RH; SAMOLS, E	1
Dunger, DB; Jackson, NC; Jones, RH; Russell-Jones, DL; Shojaee-Moradie, F; Simpson, HL; Sönksen, PH; Umpleby, AM	1
Fagerudd, JA; Forsblom, CM; Groop, PH; Kallio, J; Karvonen, MK; Koulu, M; Pesonen, U; Pettersson-Fernholm, K	1
Garlick, PJ; Godil, MA; McNurlan, MA; Wilson, TA	1
Baelde, H; Bakker, SJ; Bartram, CR; Brinkkoetter, P; Cerna, M; de Heer, E; Fischer, C; Hammes, HP; Hohenadel, D; Janssen, B; Köppel, H; Mathieson, P; Meyer, J; Nawroth, P; Peters, V; Rind, N; Romzova, M; Rondeau, E; Rychlik, I; Saleem, MA; Sauerhoefer, S; van der Woude, FJ; Yard, BA; Zirie, M; Zschocke, J	1
Andrews, JC; Jensen, MD; Moller, N; Nair, KS; Rizza, RA	1
Brismar, K; Dahlquist, G; Efendic, S; Falhammar, H; Gu, HF; Ma, J; Möllsten, A; Nordman, S	1
Bennetts, B; Craig, ME; Donaghue, KC; Duffin, AC; Gallego, PH; Hofer, S; Jenkins, AJ; Lam, A	1
Gościńska, Z	1
Ford, C; Garrow, JS; Halliday, D; Mahler, RF; Nair, KS	1
Boroujerdi, MA; Brown, PM; Carsons, ER; Hall, SE; Saunders, J; Sönksen, PH; Umpleby, AM	1
Ekberg, K; Fernqvist-Forbes, E; Ford, GC; Nair, KS; Wahren, J	1
Dahlquist, G; DeWeese, C; Kockum, I; Landin-Olsson, M; Lernmark, A; Lybrand, TP; Sanjeevi, CB; Stenger, D; Sundkvist, G	1
Biolo, G; Inchiostro, S; Tessari, P; Tiengo, A	1
Boulware, S; Caprio, S; Cline, G; Permanente, C; Sherwin, RS; Shulman, GI; Tamborlane, WV	1
Awata, T; Goto, Y; Kadowaki, H; Kadowaki, T; Mori, Y; Sakura, H; Sakuta, R; Suzuki, Y; Tanabe, Y; Tobe, K	1
Denne, SC; Kalhan, SC; Nuamah, IF; Patel, DM; Savin, SM	1
Battezzati, A; Bianchi, E; Ferrari, G; La Rocca, E; Luzi, L; Perseghin, G; Secchi, A; Spotti, D; Terruzzi, I; Vergani, S	1
Brodsky, IG; Devlin, JT	1
Balagopal, P; Charlton, MR; Nair, KS	1
Beckett, PR; Copeland, KC; Nair, KS; Vogiatzi, MG	1
Chan, A; Donaghue, K; Kao, YL; Knight, J; Silink, M	1
Charlton, MR; Nair, KS	1
Barazzoni, R; Ekberg, K; Meek, SE; Nair, KS; Wahren, J	1
Ahlman, B; Charlton, M; Nair, KS	1
Darmaun, D; Hankard, RG; Haymond, MW	1
Lee, CH; Taylor, R; Whittaker, PG	1
Broyart, JP; Gray, GM; Hampp, LT; Najjar, SM	1
Hamadeh, MJ; Hoffer, LJ	1
Bianchi, E; Cristallo, M; Di Carlo, V; Dodesini, R; Luzi, L; Pastore, MR; Piceni Sereni, L; Pozza, G; Secchi, A; Spessot, M; Terruzzi, I	1
Bruttomesso, D; Iori, E; Kiwanuka, E; Pianta, A; Tessari, P; Vettore, M; Zanetti, M	1
Centerwall, WR; Chinnock, RF; Goodman, SI; Mace, JW	1
Biolo, G; Inchiostro, S; Piccoli, A; Saggin, L; Tessari, P; Tiengo, A	1
Biolo, G; Bruttomesso, D; Carlini, M; Duner, E; Fongher, C; Inchiostro, S; Sabadin, L; Tessari, P; Tiengo, A	1
Darmaun, D; Koziet, J; Robert, JJ; Rongier, M	1
Bannister, PA; Halliday, D; Pacy, PJ	1
Halliday, D; Pacy, PJ; Thompson, GN	1
De Feo, P; Gaisano, MG; Haymond, MW	1
Bennet, WM; Connacher, AA; Jung, RT; Rennie, MJ; Stehle, P	1
Biolo, G; Boscarato, MT; De Kreutzenberg, SV; Inchiostro, S; Nosadini, R; Saccà, L; Tessari, P; Tiengo, A; Trevisan, R	1
Halliday, D; Pacy, PJ; Read, M	1
Castellino, P; DeFronzo, RA; Luzi, L; Petrides, AS; Simonson, DC	1
Bennet, WM; Connacher, AA; Jung, RT; Rennie, MJ; Smith, K	1
Ford, C; Halliday, D; Nair, KS; Pacy, PJ	1
Besch, W; Knospe, S; Köhler, E; Michaelis, D; Rjasanowski, I	1
Gerich, JE; Haymond, MW; Nissen, SL; Pehling, G; Rizza, RA; Service, FJ; Tessari, P	1
Biolo, G; Crepaldi, G; De Kreutzenberg, SV; Duner, E; Inchiostro, S; Marescotti, MC; Nosadini, R; Tessari, P; Tiengo, A; Trevisan, R	1
Ford, GC; Halliday, D; Nair, KS	1
Boroujerdi, MA; Brown, PM; Carson, ER; Sönksen, PH; Umpleby, AM	1
Beaufrere, B; Bier, DM; Desjeux, JF; Koziet, J; Lestradet, H; Robert, JJ; Young, VR	1
Garrow, JS	1
Beck, JC; McGarry, EE; Rubinstein, D	1
Söling, HD; Unger, KO	1
Kowalski, H; Lawecki, J; Rogala, H	1

Trials

9 trial(s) available for leucine and Diabetes Mellitus, Type 1

Article	Year
Decreased branched-chain amino acids and elevated fatty acids during antecedent hypoglycemia in type 1 diabetes. BMJ open diabetes research & care, 2023, Volume: 11, Issue:3 Topics: Amino Acids; Amino Acids, Branched-Chain; Blood Glucose; Diabetes Mellitus, Type 1; Fatty Acids; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Isoleucine; Leucine	2023
A High-Fiber Diet Decreases Postabsorptive Protein Turnover but Does Not Alter Insulin Sensitivity in Men with Type 1 Diabetes Mellitus. The Journal of nutrition, 2019, 04-01, Volume: 149, Issue:4 Topics: Adult; Diabetes Mellitus, Type 1; Dietary Fiber; Dietary Proteins; Humans; Insulin Resistance; Leucine; Male; Young Adult	2019
Ingestion of a protein hydrolysate is accompanied by an accelerated in vivo digestion and absorption rate when compared with its intact protein. The American journal of clinical nutrition, 2009, Volume: 90, Issue:1 Topics: Blood Glucose; Carbon Isotopes; Caseins; Cross-Over Studies; Diabetes Mellitus, Type 1; Dietary Proteins; Digestion; Glucose Tolerance Test; Humans; Insulin; Intestinal Absorption; Kinetics; Leucine; Male; Middle Aged; Muscle, Skeletal; Phenylalanine; Protein Hydrolysates	2009
Insulin-like growth factor I has a direct effect on glucose and protein metabolism, but no effect on lipid metabolism in type 1 diabetes. The Journal of clinical endocrinology and metabolism, 2004, Volume: 89, Issue:1 Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Glucagon; Glucose; Glucose Clamp Technique; Glycerol; Homeostasis; Human Growth Hormone; Humans; Insulin; Insulin-Like Growth Factor I; Kinetics; Leucine; Lipids; Lipolysis; Liver; Metabolic Clearance Rate; Oxidation-Reduction; Placebos; Proteins; Recombinant Proteins	2004
A variant of paraoxonase (PON1) gene is associated with diabetic retinopathy in IDDM. The Journal of clinical endocrinology and metabolism, 1998, Volume: 83, Issue:7 Topics: Adolescent; Amino Acid Substitution; Arginine; Aryldialkylphosphatase; Chromosome Mapping; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Esterases; Female; Genetic Variation; Glutamine; Humans; Leucine; Male; Methionine	1998
Arterial KIC as marker of liver and muscle intracellular leucine pools in healthy and type 1 diabetic humans. The American journal of physiology, 1999, Volume: 277, Issue:2 Topics: Adult; Arteries; Diabetes Mellitus, Type 1; Female; Femoral Vein; Hepatic Veins; Humans; Insulin; Keto Acids; Leucine; Liver; Male; Muscle, Skeletal; Reference Values	1999
Role of glucose in the regulation of glutamine metabolism in health and in type 1 insulin-dependent diabetes. American journal of physiology. Endocrinology and metabolism, 2000, Volume: 279, Issue:3 Topics: Adult; Blood Glucose; Breath Tests; Carbon Dioxide; Diabetes Mellitus, Type 1; Female; Glucose; Glutamine; Humans; Hypoglycemic Agents; Infusions, Intravenous; Insulin; Leucine; Male; Oxidation-Reduction; Radioisotope Dilution Technique	2000
Effect of protein restriction on (15)N transfer from dietary [(15)N]alanine and [(15)N]Spirulina platensis into urea. American journal of physiology. Endocrinology and metabolism, 2001, Volume: 281, Issue:2 Topics: Alanine; Aspartic Acid; Bacterial Proteins; Diabetes Mellitus, Type 1; Diet, Protein-Restricted; Female; Gas Chromatography-Mass Spectrometry; Glutamine; Glycine; Humans; Isoleucine; Leucine; Male; Methionine; Nitrogen Isotopes; Postprandial Period; Spirulina; Urea	2001
Measurement of whole-body protein turnover in insulin-dependent (type 1) diabetic patients during insulin withdrawal and infusion: comparison of [13C]leucine and [2H5]phenylalanine methodologies. Clinical science (London, England : 1979), 1991, Volume: 80, Issue:4 Topics: Adult; Diabetes Mellitus, Type 1; Female; Humans; Insulin; Leucine; Male; Models, Biological; Phenylalanine; Protein Biosynthesis; Proteins	1991

Other Studies

61 other study(ies) available for leucine and Diabetes Mellitus, Type 1

Article	Year
Aminoaciduria and metabolic dysregulation during diabetic ketoacidosis: Results from the diabetic kidney alarm (DKA) study. Journal of diabetes and its complications, 2022, Volume: 36, Issue:6 Topics: Adolescent; Amino Acids; Child; Creatinine; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Diabetic Nephropathies; Female; Histidine; Humans; Leucine; Male; Threonine; Tryptophan	2022
Plasma leucine-rich α-2-glycoprotein 1 - a novel marker of diabetic kidney disease in children and adolescents with type 1 diabetes mellitus? Pediatric nephrology (Berlin, Germany), 2023, Volume: 38, Issue:12 Topics: Adolescent; Albuminuria; Child; Cystatin C; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Glomerular Filtration Rate; Glycoproteins; Humans; Leucine	2023
Leucine and resistance training improve hyperglycemia, white adipose tissue loss, and inflammatory parameters in an experimental model of type 1 diabetes. Nutrition and health, 2018, Volume: 24, Issue:1 Topics: Adiponectin; Adipose Tissue, White; Adiposity; Animals; Anti-Inflammatory Agents, Non-Steroidal; Combined Modality Therapy; Diabetes Mellitus, Type 1; Dietary Supplements; Gene Expression Regulation; Hyperglycemia; Inflammation Mediators; Insulin Resistance; Intra-Abdominal Fat; Leptin; Leucine; Male; Random Allocation; Rats, Wistar; Resistance Training; Weight Loss	2018
Longitudinal associations of nutritional factors with glycated hemoglobin in youth with type 1 diabetes: the SEARCH Nutrition Ancillary Study. The American journal of clinical nutrition, 2015, Volume: 101, Issue:6 Topics: Adolescent; Biomarkers; Blood Glucose; Body Mass Index; Child; Diabetes Mellitus, Type 1; Dietary Carbohydrates; Dietary Fats; Dietary Fiber; Dietary Proteins; Docosahexaenoic Acids; Eicosapentaenoic Acid; Energy Intake; Female; Follow-Up Studies; Glycated Hemoglobin; Humans; Leucine; Longitudinal Studies; Male; Nutrition Assessment; Nutritional Status; Surveys and Questionnaires; Vitamin D; Vitamin E	2015
Protein and glutamine kinetics during counter-regulatory failure in type 1 diabetes. Nutrition, metabolism, and cardiovascular diseases : NMCD, 2009, Volume: 19, Issue:5 Topics: Adult; Blood Glucose; Case-Control Studies; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Gluconeogenesis; Glucose; Glucose Clamp Technique; Glutamine; Humans; Hypoglycemia; Insulin; Leucine; Male; Metabolic Clearance Rate	2009
Time-dependent changes in the plasma amino acid concentration in diabetes mellitus. Molecular genetics and metabolism, 2011, Volume: 103, Issue:4 Topics: Alanine; Amino Acids; Amino Acids, Branched-Chain; Animals; Blood Glucose; Diabetes Mellitus, Type 1; Insulin; Isoleucine; Leucine; Longitudinal Studies; Mice; Mice, Inbred Strains	2011
Regulation of cathepsin G reduces the activation of proinsulin-reactive T cells from type 1 diabetes patients. PloS one, 2011, Volume: 6, Issue:8 Topics: Blotting, Western; Carrier Proteins; Cathepsin G; Cell-Penetrating Peptides; Cells, Cultured; Diabetes Mellitus, Type 1; Enzyme-Linked Immunosorbent Assay; Humans; Leucine; Pepstatins; Polymerase Chain Reaction; Proinsulin; T-Lymphocytes	2011
Rapamycin protects against dominant negative-HNF1A-induced apoptosis in INS-1 cells. Apoptosis : an international journal on programmed cell death, 2011, Volume: 16, Issue:11 Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Cell Survival; Diabetes Mellitus, Type 1; Gene Expression Regulation; Genes, Dominant; Hepatocyte Nuclear Factor 1-alpha; Insulin-Secreting Cells; Insulinoma; Leucine; Mutation; Pancreatic Neoplasms; Protein Processing, Post-Translational; Rats; Real-Time Polymerase Chain Reaction; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases	2011
Voluntary physical activity and leucine correct impairments in muscle protein synthesis in partially pancreatectomised rats. Diabetologia, 2011, Volume: 54, Issue:12 Topics: Animals; Blood Glucose; Carrier Proteins; Diabetes Mellitus, Type 1; Intracellular Signaling Peptides and Proteins; Leucine; Male; Motor Activity; Muscle Proteins; Muscle, Skeletal; Phosphoproteins; Phosphorylation; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases; Sedentary Behavior	2011
Anti-serpin antibody-mediated regulation of proteases in autoimmune diabetes. The Journal of biological chemistry, 2013, Jan-18, Volume: 288, Issue:3 Topics: Animals; Antibodies, Monoclonal; Antibodies, Neutralizing; Antigens, CD19; Autoantibodies; CD4 Antigens; Cysteine Proteinase Inhibitors; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Progression; Female; Gene Expression; Immunity, Humoral; Interferon-gamma; Islets of Langerhans; Leucine; Lymph Nodes; Mice; Mice, Inbred NOD; Serpins; T-Lymphocytes	2013
[EFFECT OF LEUCINE ON GLYCEMIA IN DIABETES IN CHILDREN]. Pediatria polska, 1964, Volume: 39 Topics: Adolescent; Blood Glucose; Child; Diabetes Mellitus; Diabetes Mellitus, Type 1; Epinephrine; Humans; Hypoglycemia; Leucine; Pharmacology; Phenylketonurias	1964
SOME METABOLIC CHANGES INDUCED BY PRIMATE GROWTH HORMONE AND PURIFIED OVINE PROLACIN. Metabolism: clinical and experimental, 1964, Volume: 13 Topics: Adipose Tissue; Animals; Calcium; Carbohydrate Metabolism; Carbon Dioxide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Dwarfism; Dwarfism, Pituitary; Fatty Acids; Glycerides; Glycogen; Growth Hormone; Hypopituitarism; Kidney Function Tests; Leucine; Lipid Metabolism; Metabolism; Pharmacology; Primates; Prolactin; Research; Sheep	1964
LIPOATROPHIC DIABETES. I. STUDIES CONCERNING ENDOCRINE FUNCTION AND CARBOHYDRATE METABOLISM. American journal of diseases of children (1960), 1965, Volume: 109 Topics: Adolescent; Carbohydrate Metabolism; Diabetes Mellitus, Lipoatrophic; Diabetes Mellitus, Type 1; Drug Tolerance; Epinephrine; Fatty Acids; Glucagon; Glucose Tolerance Test; Hepatomegaly; Humans; Infant; Insulin; Insulin Resistance; L-Lactate Dehydrogenase; Leucine; Lipids; Lipodystrophy; Liver; Liver Cirrhosis; Liver Function Tests; Metyrapone; Pharmacology; Pituitary-Adrenal Function Tests; Radiography; Tolbutamide; Transaminases; Urine	1965
Leucine 7 to proline 7 polymorphism in the preproneuropeptide Y is associated with proteinuria, coronary heart disease, and glycemic control in type 1 diabetic patients. Diabetes care, 2004, Volume: 27, Issue:2 Topics: Adult; Amino Acid Substitution; Blood Glucose; Body Mass Index; Cholesterol; Coronary Disease; Diabetes Mellitus, Type 1; Female; Genotype; Glycated Hemoglobin; Humans; Leucine; Male; Mutation, Missense; Neuropeptide Y; Proline; Protein Precursors; Proteinuria; Risk Factors; Triglycerides	2004
Effect of insulin with concurrent amino acid infusion on protein metabolism in rapidly growing pubertal children with type 1 diabetes. Pediatric research, 2005, Volume: 58, Issue:2 Topics: Adolescent; Amino Acids; Blood Glucose; Child; Diabetes Mellitus, Type 1; Glucose; Humans; Insulin; Kinetics; Leucine; Male; Proteins; Time Factors	2005
Carnosine as a protective factor in diabetic nephropathy: association with a leucine repeat of the carnosinase gene CNDP1. Diabetes, 2005, Volume: 54, Issue:8 Topics: Aged; Carnosine; Cells, Cultured; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dipeptidases; Female; Gene Expression; Genetic Predisposition to Disease; Glucose; Humans; Kidney; Leucine; Male; Middle Aged; Repetitive Sequences, Amino Acid; RNA, Messenger; Sequence Alignment	2005
Renal amino acid, fat and glucose metabolism in type 1 diabetic and non-diabetic humans: effects of acute insulin withdrawal. Diabetologia, 2006, Volume: 49, Issue:8 Topics: Amino Acids; Blood Flow Velocity; Diabetes Mellitus, Type 1; Glucose; Humans; Hypoglycemic Agents; Insulin; Kidney; Leucine; Palmitic Acid; Phenylalanine; Reference Values; Renal Circulation; Substance Withdrawal Syndrome; Tyrosine	2006
Distribution of neuropeptide Y Leu7Pro polymorphism in patients with type 1 diabetes and diabetic nephropathy among Swedish and American populations. European journal of endocrinology, 2007, Volume: 157, Issue:5 Topics: Adult; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Leucine; Male; Middle Aged; Neuropeptide Y; Polymorphism, Single Nucleotide; Proline; Sweden; United States	2007
Association between p.Leu54Met polymorphism at the paraoxonase-1 gene and plantar fascia thickness in young subjects with type 1 diabetes. Diabetes care, 2008, Volume: 31, Issue:8 Topics: Adolescent; Amino Acid Substitution; Arginine; Aryldialkylphosphatase; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Fasciitis, Plantar; Female; Glutamine; Humans; Leucine; Male; Methionine; New South Wales; Polymorphism, Single Nucleotide; White People	2008
[Effect of leucine on glycemia in childhood diabetes]. Folia medica Cracoviensia, 1967, Volume: 9, Issue:1 Topics: Adolescent; Child; Diabetes Mellitus, Type 1; Humans; Hypoglycemia; Leucine	1967
Effect of poor diabetic control and obesity on whole body protein metabolism in man. Diabetologia, 1983, Volume: 25, Issue:5 Topics: Adult; Bicarbonates; Blood Glucose; C-Peptide; Carbon Isotopes; Diabetes Mellitus, Type 1; Female; Humans; Insulin; Leucine; Male; Obesity; Proteins; Reference Values; Sodium Bicarbonate	1983
Isotope turnover studies in uncontrolled diabetes and the effects of insulin. Ciba Foundation symposium, 1982, Volume: 87 Topics: Blood Glucose; Carbon Radioisotopes; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Humans; Insulin; Ketone Bodies; Leucine; Metabolic Clearance Rate; Oxygen Consumption; Tritium	1982
Protein dynamics in whole body and in splanchnic and leg tissues in type I diabetic patients. The Journal of clinical investigation, 1995, Volume: 95, Issue:6 Topics: Adult; Carbohydrate Metabolism; Diabetes Mellitus, Type 1; Hormones; Humans; Insulin; Leg; Leucine; Male; Muscle Proteins; Phenylalanine; Proteins; Regional Blood Flow; Splanchnic Circulation; Tyrosine	1995
Polymorphic amino acid variations in HLA-DQ are associated with systematic physical property changes and occurrence of IDDM. Members of the Swedish Childhood Diabetes Study. Diabetes, 1995, Volume: 44, Issue:1 Topics: Adolescent; Amino Acid Sequence; Amino Acids; Arginine; Aspartic Acid; Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; Gene Amplification; Genotype; HLA-DQ Antigens; Humans; Incidence; Infant; Leucine; Male; Models, Molecular; Molecular Sequence Data; Polymorphism, Genetic; Sweden	1995
Regulation of postprandial whole-body proteolysis in insulin-deprived IDDM. Diabetes, 1995, Volume: 44, Issue:2 Topics: Adult; Amino Acids; Blood Glucose; Deuterium; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Food; Food, Formulated; Humans; Hydrogen-Ion Concentration; Insulin; Kinetics; Leucine; Male; Middle Aged; Phenylalanine; Proteins	1995
Effects of puberty and diabetes on metabolism of insulin-sensitive fuels. The American journal of physiology, 1994, Volume: 266, Issue:6 Pt 1 Topics: Adolescent; Adult; Amino Acids; Arteries; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Glucose; Humans; Insulin; Kinetics; Leucine; Lipid Metabolism; Male; Proteins; Puberty	1994
A subtype of diabetes mellitus associated with a mutation of mitochondrial DNA. The New England journal of medicine, 1994, Apr-07, Volume: 330, Issue:14 Topics: Adolescent; Adult; Aged; Base Sequence; Child; Child, Preschool; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; DNA, Mitochondrial; Female; Humans; Insulin Resistance; Leucine; Male; Middle Aged; Molecular Sequence Data; Mutation; Pedigree	1994
Leucine kinetics during a brief fast in diabetes in pregnancy. Metabolism: clinical and experimental, 1994, Volume: 43, Issue:3 Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes, Gestational; Fasting; Female; Glycated Hemoglobin; Humans; Infusion Pumps; Insulin; Leucine; Oxidation-Reduction; Pregnancy; Pregnancy Trimester, Third; Time Factors	1994
Combined pancreas and kidney transplantation normalizes protein metabolism in insulin-dependent diabetic-uremic patients. The Journal of clinical investigation, 1994, Volume: 93, Issue:5 Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Hemoglobins; Hormones; Humans; Hyperinsulinism; Immunosuppression Therapy; Keto Acids; Kidney Failure, Chronic; Kidney Transplantation; Leucine; Male; Nitrogen; Oxidation-Reduction; Pancreas Transplantation; Proteins; Uremia; Uveitis, Posterior	1994
Effects of dietary protein restriction on regional amino acid metabolism in insulin-dependent diabetes mellitus. The American journal of physiology, 1996, Volume: 270, Issue:1 Pt 1 Topics: Alanine; Amino Acids; Blood Glucose; Diabetes Mellitus, Type 1; Dietary Proteins; Dose-Response Relationship, Drug; Female; Forearm; Humans; Insulin; Leucine; Male; Nitrogen; Reference Values	1996
Skeletal muscle myosin heavy chain synthesis in type 1 diabetes. Diabetes, 1997, Volume: 46, Issue:8 Topics: Adult; Amino Acids; Biopsy; Caproates; Carbon Isotopes; Diabetes Mellitus, Type 1; Female; Humans; Hypoglycemic Agents; Infusions, Intravenous; Insulin; Leucine; Male; Muscle Proteins; Muscle, Skeletal; Myosin Heavy Chains; Time Factors	1997
Insulin does not stimulate protein synthesis acutely in prepubertal children with insulin-dependent diabetes mellitus. The Journal of clinical endocrinology and metabolism, 1997, Volume: 82, Issue:12 Topics: Amino Acids; Child; Diabetes Mellitus, Type 1; Female; Hormones; Humans; Hypoglycemic Agents; Insulin; Kinetics; Leucine; Male; Osmolar Concentration; Protein Biosynthesis; Puberty; Time Factors	1997
Role of hyperglucagonemia in catabolism associated with type 1 diabetes: effects on leucine metabolism and the resting metabolic rate. Diabetes, 1998, Volume: 47, Issue:11 Topics: Adult; Amino Acids; Basal Metabolism; Calorimetry, Indirect; Diabetes Mellitus, Type 1; Energy Metabolism; Female; Glucagon; Humans; Insulin; Kinetics; Leucine; Male; Oxidation-Reduction; Proteins; Regression Analysis; Somatostatin	1998
The effect of insulin on human small intestinal mucosal protein synthesis. Gastroenterology, 2000, Volume: 118, Issue:2 Topics: Adult; Amino Acids; Blood Glucose; Carbon Isotopes; Diabetes Mellitus, Type 1; Female; Hormones; Humans; Insulin; Intestinal Mucosa; Intestine, Small; Kinetics; Leucine; Male; Middle Aged; Protein Biosynthesis; Reference Values; Sodium Bicarbonate	2000
Whole body protein kinetics in women: effect of pregnancy and IDDM during anabolic stimulation. American journal of physiology. Endocrinology and metabolism, 2000, Volume: 279, Issue:5 Topics: Amino Acids; Blood Glucose; Carbon Isotopes; Deuterium; Diabetes Mellitus, Type 1; Female; Glucose Clamp Technique; Humans; Hydroxylation; Insulin; Kinetics; Leucine; Oxidation-Reduction; Phenylalanine; Pregnancy; Pregnancy in Diabetics; Proteins	2000
Intestinal aminooligopeptidase in diabetic BioBreed rat: altered posttranslational processing and trafficking. American journal of physiology. Gastrointestinal and liver physiology, 2001, Volume: 280, Issue:1 Topics: Animals; CD13 Antigens; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Endoplasmic Reticulum; Enterocytes; Female; Glycosylation; Golgi Apparatus; Humans; Jejunum; Kinetics; Leucine; Male; Mannose; Methionine; Microvilli; Protein Processing, Post-Translational; Protein Transport; Rats; Rats, Inbred BB; Rats, Wistar; Sulfur Radioisotopes; Tritium	2001
Postabsorptive muscle protein metabolism in type 1 diabetic patients after pancreas transplantation. Acta diabetologica, 2000, Volume: 37, Issue:4 Topics: Adult; Blood Glucose; C-Peptide; Cyclosporine; Diabetes Mellitus, Type 1; Energy Intake; Forearm; Glycated Hemoglobin; Humans; Immunosuppressive Agents; Insulin; Leucine; Middle Aged; Muscle Proteins; Muscle, Skeletal; Pancreas Transplantation; Phenylalanine; Prednisone; Protein Biosynthesis; Proteins; Reference Values; Regional Blood Flow	2000
Effects of wine intake on postprandial plasma amino acid and protein kinetics in type 1 diabetes. The American journal of clinical nutrition, 2002, Volume: 75, Issue:5 Topics: Adult; Alcohol Drinking; Amino Acids; Blood Glucose; Blood Proteins; Diabetes Mellitus, Type 1; Female; Fibrinogen; Glycated Hemoglobin; Hormones; Humans; Hypoglycemic Agents; Insulin; Kinetics; Leucine; Male; Oxidation-Reduction; Phenylalanine; Postprandial Period; Wine	2002
The child with an unusual odor. A clinical resumé. Clinical pediatrics, 1976, Volume: 15, Issue:1 Topics: Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Choline; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Humans; Infant; Leucine; Maple Syrup Urine Disease; Metabolism, Inborn Errors; Methionine; Odorants; Phenylketonurias; Tyrosine	1976
Relationship between plasma leucine concentration and clearance in normal and type 1 diabetic subjects. Acta diabetologica, 1992, Volume: 29, Issue:1 Topics: Adult; Analysis of Variance; Diabetes Mellitus, Type 1; Female; Humans; Leucine; Male; Metabolic Clearance Rate; Radioisotope Dilution Technique; Reference Values; Tritium	1992
Effects of insulin and amino acid infusion on leucine and phenylalanine kinetics in type 1 diabetes. The American journal of physiology, 1992, Volume: 262, Issue:2 Pt 1 Topics: Amino Acids; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Clamp Technique; Humans; Infusions, Intravenous; Insulin; Keto Acids; Kinetics; Leucine; Male; Phenylalanine	1992
Glutamine nitrogen kinetics in insulin-dependent diabetic humans. The American journal of physiology, 1991, Volume: 261, Issue:6 Pt 1 Topics: Adult; Diabetes Mellitus, Type 1; Glutamine; Humans; Hyperglycemia; Insulin; Kinetics; Leucine; Male; Nitrogen	1991
Influence of insulin on leucine kinetics in the whole body and across the forearm in post-absorptive insulin dependent diabetic (type 1) patients. Diabetes research (Edinburgh, Scotland), 1991, Volume: 18, Issue:4 Topics: Adult; Blood Glucose; Carbon Isotopes; Diabetes Mellitus, Type 1; Forearm; Glucagon; Humans; Insulin; Isotope Labeling; Ketone Bodies; Kinetics; Leucine; Male; Nitrogen Isotopes; Oxygen Consumption; Proteins	1991
Differential effects of insulin deficiency on albumin and fibrinogen synthesis in humans. The Journal of clinical investigation, 1991, Volume: 88, Issue:3 Topics: Adult; Albumins; Amino Acids; Carbon Dioxide; Catecholamines; Diabetes Mellitus, Type 1; Female; Fibrinogen; Humans; Hydrogen-Ion Concentration; Insulin; Leucine; Male	1991
Effects of insulin and amino acids on leg protein turnover in IDDM patients. Diabetes, 1991, Volume: 40, Issue:4 Topics: Adult; Amino Acids; Carbon Isotopes; Diabetes Mellitus, Type 1; Female; Humans; Insulin; Kinetics; Leucine; Male; Mathematics; Models, Biological; Muscles; Nitrogen Isotopes; Phenylalanine; Proteins; Reference Values	1991
Effects of insulin on whole body and forearm leucine and KIC metabolism in type 1 diabetes. The American journal of physiology, 1990, Volume: 259, Issue:1 Pt 1 Topics: Adult; Blood Glucose; Caproates; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Forearm; Humans; Insulin; Keto Acids; Ketone Bodies; Kinetics; Leucine; Male; Muscles; Regional Blood Flow	1990
Influence of insulin on albumin and non-albumin protein fractional synthetic rates in post-absorptive type I diabetic patients. European journal of clinical nutrition, 1990, Volume: 44, Issue:5 Topics: Adult; Albumins; Blood Proteins; Carbon Isotopes; Diabetes Mellitus, Type 1; Female; Humans; Infusions, Intravenous; Insulin; Leucine; Male; Middle Aged; Stimulation, Chemical	1990
Leucine metabolism in IDDM. Role of insulin and substrate availability. Diabetes, 1990, Volume: 39, Issue:1 Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Epinephrine; Female; Glucagon; Glucose; Glycated Hemoglobin; Humans; Hydrocortisone; Insulin; Keto Acids; Leucine; Male; Norepinephrine	1990
Inability to stimulate skeletal muscle or whole body protein synthesis in type 1 (insulin-dependent) diabetic patients by insulin-plus-glucose during amino acid infusion: studies of incorporation and turnover of tracer L-[1-13C]leucine. Diabetologia, 1990, Volume: 33, Issue:1 Topics: 3-Hydroxybutyric Acid; Amino Acids; Blood Glucose; Carbon Isotopes; Diabetes Mellitus, Type 1; Glucagon; Glucose; Humans; Hydrocortisone; Hydroxybutyrates; Insulin; Insulin-Like Growth Factor I; Isotope Labeling; Kinetics; Leucine; Male; Muscles; Protein Biosynthesis	1990
Failure of insulin infusion to stimulate fractional muscle protein synthesis in type I diabetic patients. Anabolic effect of insulin and decreased proteolysis. Diabetes, 1989, Volume: 38, Issue:5 Topics: Adult; Diabetes Mellitus, Type 1; Female; Humans; Infusions, Intravenous; Insulin; Leucine; Male; Middle Aged; Muscle Proteins	1989
Persistence of anti-islet ADCC after manifestation of type-1 (insulin-dependent) diabetes. Experimental and clinical endocrinology, 1989, Volume: 94, Issue:3 Topics: Adolescent; Adult; Antibody-Dependent Cell Cytotoxicity; C-Peptide; Diabetes Mellitus, Type 1; Female; Humans; Islets of Langerhans; Leucine; Male	1989
Regulation of whole-body leucine metabolism with insulin during mixed-meal absorption in normal and diabetic humans. Diabetes, 1988, Volume: 37, Issue:5 Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Eating; Female; Humans; Insulin; Leucine; Male	1988
Defective suppression by insulin of leucine-carbon appearance and oxidation in type 1, insulin-dependent diabetes mellitus. Evidence for insulin resistance involving glucose and amino acid metabolism. The Journal of clinical investigation, 1986, Volume: 77, Issue:6 Topics: Adult; Amino Acids; Blood Glucose; Carbon; Diabetes Mellitus, Type 1; Humans; Insulin; Insulin Resistance; Keto Acids; Leucine; Male; Oxidation-Reduction	1986
Effect of intravenous insulin treatment on in vivo whole body leucine kinetics and oxygen consumption in insulin-deprived type I diabetic patients. Metabolism: clinical and experimental, 1987, Volume: 36, Issue:5 Topics: Adult; Diabetes Mellitus, Type 1; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Injections, Intravenous; Insulin; Kinetics; Leucine; Male; Metabolic Clearance Rate; Oxidation-Reduction; Oxygen Consumption	1987
The effect of metabolic control on leucine metabolism in type 1 (insulin-dependent) diabetic patients. Diabetologia, 1986, Volume: 29, Issue:3 Topics: Adolescent; Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 1; Female; Humans; Ketones; Leucine; Male; Metabolic Clearance Rate; Middle Aged; Models, Biological; Oxidation-Reduction; Protein Biosynthesis	1986
Whole body de novo amino acid synthesis in type I (insulin-dependent) diabetes studied with stable isotope-labeled leucine, alanine, and glycine. Diabetes, 1985, Volume: 34, Issue:1 Topics: Adolescent; Adult; Alanine; Amino Acids; Diabetes Mellitus, Type 1; Glucose; Glycine; Humans; Hyperglycemia; Insulin; Kinetics; Leucine; Male	1985
The contribution of protein synthesis to thermogenesis in man. International journal of obesity, 1985, Volume: 9 Suppl 2 Topics: Animals; Basal Metabolism; Body Temperature Regulation; Diabetes Mellitus, Type 1; Eating; Humans; Insulin; Leucine; Models, Biological; Muscles; Protein Biosynthesis; Rats; Starvation	1985
Growth hormones and prolactins: biochemical, immunological, and physiological similarities and differences. Annals of the New York Academy of Sciences, 1968, Feb-05, Volume: 148, Issue:2 Topics: Adolescent; Blood Glucose; Blood Urea Nitrogen; Carbohydrate Metabolism; Carbon Isotopes; Diabetes Mellitus, Type 1; Dwarfism, Pituitary; Fasting; Fatty Acids, Nonesterified; Glycosuria; Growth Hormone; Humans; Immunodiffusion; Leucine; Nitrogen; Prolactin; Proteins; Testosterone	1968
The role of insulin in the regulation of -amylase synthesis in the rat pancreas. European journal of clinical investigation, 1972, Volume: 2, Issue:4 Topics: Adrenalectomy; Amino Sugars; Amylases; Animals; Anti-Bacterial Agents; Chymotrypsin; Dactinomycin; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diazoxide; Insulin; Leucine; Nitroso Compounds; Pancreas; Proteins; Rats; Rats, Inbred Strains; Trypsin	1972
Studies on the radioimmunological determination of blood insulin by means of 125-I-insulin of high specific activity. Polish medical journal, 1970, Volume: 9, Issue:6 Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Animals; Blood Glucose; Diabetes Mellitus, Type 1; Fasting; Female; Glucagon; Glucose; Humans; Infant; Insulin; Iodine Isotopes; Leucine; Methods; Obesity; Radioimmunoassay; Swine; Tolbutamide	1970
[Effect of leucine on the blood sugar level in children diabetes. II. In vitro studies]. Pediatria polska, 1965, Volume: 40, Issue:12 Topics: Animals; Diabetes Mellitus, Type 1; Epinephrine; Insulin; Leucine; Rats	1965