leucine has been researched along with Diabetes Mellitus, Adult-Onset in 142 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (1.41) | 18.7374 |
| 1990's | 14 (9.86) | 18.2507 |
| 2000's | 48 (33.80) | 29.6817 |
| 2010's | 43 (30.28) | 24.3611 |
| 2020's | 35 (24.65) | 2.80 |
| Authors | Studies |
|---|---|
| Ang, K; Gurung, RL; Lee, J; Lim, SC; Liu, JJ; Liu, S; Pek, SLT; Shao, YM; Sum, CF; Tang, WE; Tavintharan, S; Wang, J | 2 |
| Cai, G; Cai, H; Chen, XM; He, JC; Hong, Q; Lee, K; Li, Z; Ni, Z; Zhang, L; Zhong, F | 1 |
| Jin, W; Li, W; Li, XL; Min, JZ; Qi, C; Zhao, LL | 1 |
| Ang, K; Ang, SF; Ching, J; Kovalik, JP; Lee, LS; Lim, SC; Lim, Z; Low, S; Moh, A; Shao, YM; Subramaniam, T; Sum, CF; Tang, WE; Wang, J; Wee, HN | 1 |
| Cao, YF; Cui, XT; Gao, ZN; Huang, B; Li, S; Liu, ML | 1 |
| Capparelli, R; Cuomo, P; Iannelli, A; Iannelli, D | 1 |
| Beatrice, G; Bonapace, S; Csermely, A; Lippi, G; Lunardi, G; Mantovani, A; Petracca, G; Sani, E; Targher, G | 1 |
| Lenart-Lipinska, M; Matyjaszek-Matuszek, B; Szmygin, H; Szydelko, J; Wozniak, S | 1 |
| Huang, C; Lin, D; Lu, R; Zhang, Y; Zhou, L; Zou, H | 1 |
| Gu, Y; Qiang, W; Sun, Y; Wu, R; Yin, T; Yuan, J | 1 |
| Álvarez, C; Álvarez-Cilleros, D; Amigó, N; Chagoyen, M; Correig, X; Fernández-Millán, E; Martín, MÁ; Ramos, S; Samino, S | 1 |
| Ardavani, A; Atherton, PJ; Idris, I; Mellett, A; Ramzan, I; Vanweert, F | 1 |
| Fujita, Y; Furuya, F; Ikeda, K; Inagaki, N; Isomura, N; Kondo, A; Li, Y; Mano, F; Matsuo, N; Minamino, H; Oguri, Y; Takesue, K | 1 |
| Kamei, Y; Sugimoto, T | 1 |
| Barouki, R; Coumoul, X; De Bandt, JP | 1 |
| Ao, Q; Chen, C; Ding, H; Du, B; Feng, M; Huang, Y; Lei, Y; Li, X; Li, Y; Liang, N; Liao, S; Lu, C; Mo, J; Shi, Q; Tang, S; Tang, T; Wang, X; Wei, L; Wu, Y; Zhang, N; Zheng, Z | 1 |
| Amoroso, AP; Capaldo, B; Castaldo, C; Della Pepa, G; Izzo, A; Massimino, E; Rivellese, AA | 1 |
| He, A; Shen, X; Shi, C; Wan, Y; Wu, X; Yang, J; Zhou, Y; Zhu, X | 1 |
| Fukui, M; Hamaguchi, M; Hashimoto, Y; Kobayashi, A; Nakajima, H; Nakanishi, N; Okada, H; Okamura, T; Senmaru, T; Takahashi, F; Ushigome, E | 1 |
| Li, HL; Li, ZY; Shen, QM; Tan, YT; Tuo, JY; Wang, J; Xiang, YB | 1 |
| Chen, A; Dong, Q; Feng, L; Fu, M; Lan, Z; Li, L; Li, Y; Liang, Q; Liu, X; Lu, L; Wang, S; Xie, L; Yan, J; Yang, X; Ye, Y | 1 |
| Baek, HS; Kang, HM; Kim, IR; Kim, YS; Oh, JM; Park, BS | 1 |
| Cho, DH; Chung, DJ; Chung, JO; Chung, MY; Park, SY | 1 |
| Izadi, N; Mohseni, P; Najafi, F; Niknam, M; Pasdar, Y | 1 |
| Berska, J; Bugajska, J; Gotfryd-Bugajska, K; Pasternak, A; Sztefko, K; Szura, M | 1 |
| Abbasi, S; Abd El-Wahab, A; Abdallah, M; Abebe, G; Aca-Aca, G; Adama, S; Adefegha, SA; Adidigue-Ndiome, R; Adiseshaiah, P; Adrario, E; Aghajanian, C; Agnese, W; Ahmad, A; Ahmad, I; Ahmed, MFE; Akcay, OF; Akinmoladun, AC; Akutagawa, T; Alakavuklar, MA; Álava-Rabasa, S; Albaladejo-Florín, MJ; Alexandra, AJE; Alfawares, R; Alferiev, IS; Alghamdi, HS; Ali, I; Allard, B; Allen, JD; Almada, E; Alobaid, A; Alonso, GL; Alqahtani, YS; Alqarawi, W; Alsaleh, H; Alyami, BA; Amaral, BPD; Amaro, JT; Amin, SAW; Amodio, E; Amoo, ZA; Andia Biraro, I; Angiolella, L; Anheyer, D; Anlay, DZ; Annex, BH; Antonio-Aguirre, B; Apple, S; Arbuznikov, AV; Arinsoy, T; Armstrong, DK; Ash, S; Aslam, M; Asrie, F; Astur, DC; Atzrodt, J; Au, DW; Aucoin, M; Auerbach, EJ; Azarian, S; Ba, D; Bai, Z; Baisch, PRM; Balkissou, AD; Baltzopoulos, V; Banaszewski, M; Banerjee, S; Bao, Y; Baradwan, A; Barandika, JF; Barger, PM; Barion, MRL; Barrett, CD; Basudan, AM; Baur, LE; Baz-Rodríguez, SA; Beamer, P; Beaulant, A; Becker, DF; Beckers, C; Bedel, J; Bedlack, R; Bermúdez de Castro, JM; Berry, JD; Berthier, C; Bhattacharya, D; Biadgo, B; Bianco, G; Bianco, M; Bibi, S; Bigliardi, AP; Billheimer, D; Birnie, DH; Biswas, K; Blair, HC; Bognetti, P; Bolan, PJ; Bolla, JR; Bolze, A; Bonnaillie, P; Borlimi, R; Bórquez, J; Bottari, NB; Boulleys-Nana, JR; Brighetti, G; Brodeur, GM; Budnyak, T; Budnyk, S; Bukirwa, VD; Bulman, DM; Burm, R; Busman-Sahay, K; Butcher, TW; Cai, C; Cai, H; Cai, L; Cairati, M; Calvano, CD; Camacho-Ordóñez, A; Camela, E; Cameron, T; Campbell, BS; Cansian, RL; Cao, Y; Caporale, AS; Carciofi, AC; Cardozo, V; Carè, J; Carlos, AF; Carozza, R; Carroll, CJW; Carsetti, A; Carubelli, V; Casarotta, E; Casas, M; Caselli, G; Castillo-Lora, J; Cataldi, TRI; Cavalcante, ELB; Cavaleiro, A; Cayci, Z; Cebrián-Tarancón, C; Cedrone, E; Cella, D; Cereda, C; Ceretti, A; Ceroni, M; Cha, YH; Chai, X; Chang, EF; Chang, TS; Chanteux, H; Chao, M; Chaplin, BP; Chaturvedi, S; Chaturvedi, V; Chaudhary, DK; Chen, A; Chen, C; Chen, HY; Chen, J; Chen, JJ; Chen, K; Chen, L; Chen, Q; Chen, R; Chen, SY; Chen, TY; Chen, WM; Chen, X; Chen, Y; Cheng, G; Cheng, GJ; Cheng, J; Cheng, YH; Cheon, HG; Chew, KW; Chhoker, S; Chiu, WN; Choi, ES; Choi, MJ; Choi, SD; Chokshi, S; Chorny, M; Chu, KI; Chu, WJ; Church, AL; Cirrincione, A; Clamp, AR; Cleff, MB; Cohen, M; Coleman, RL; Collins, SL; Colombo, N; Conduit, N; Cong, WL; Connelly, MA; Connor, J; Cooley, K; Correa Ramos Leal, I; Cose, S; Costantino, C; Cottrell, M; Cui, L; Cundall, J; Cutaia, C; Cutler, CW; Cuypers, ML; da Silva Júnior, FMR; Dahal, RH; Damiani, E; Damtie, D; Dan-Li, W; Dang, Z; Dasa, SSK; Davin, A; Davis, DR; de Andrade, CM; de Jong, PL; de Oliveira, D; de Paula Dorigam, JC; Dean, A; Deepa, M; Delatour, C; Dell'Aiera, S; Delley, MF; den Boer, RB; Deng, L; Deng, Q; Depner, RM; Derdau, V; Derici, U; DeSantis, AJ; Desmarini, D; Diffo-Sonkoue, L; Divizia, M; Djenabou, A; Djordjevic, JT; Dobrovolskaia, MA; Domizi, R; Donati, A; Dong, Y; Dos Santos, M; Dos Santos, MP; Douglas, RG; Duarte, PF; Dullaart, RPF; Duscha, BD; Edwards, LA; Edwards, TE; Eichenwald, EC; El-Baba, TJ; Elashiry, M; Elashiry, MM; Elashry, SH; Elliott, A; Elsayed, R; Emerson, MS; Emmanuel, YO; Emory, TH; Endale-Mangamba, LM; Enten, GA; Estefanía-Fernández, K; Estes, JD; Estrada-Mena, FJ; Evans, S; Ezra, L; Faria de, RO; Farraj, AK; Favre, C; Feng, B; Feng, J; Feng, L; Feng, W; Feng, X; Feng, Z; Fernandes, CLF; Fernández-Cuadros, ME; Fernie, AR; Ferrari, D; Florindo, PR; Fong, PC; Fontes, EPB; Fontinha, D; Fornari, VJ; Fox, NP; Fu, Q; Fujitaka, Y; Fukuhara, K; Fumeaux, T; Fuqua, C; Fustinoni, S; Gabbanelli, V; Gaikwad, S; Gall, ET; Galli, A; Gancedo, MA; Gandhi, MM; Gao, D; Gao, K; Gao, M; Gao, Q; Gao, X; Gao, Y; Gaponenko, V; Garber, A; Garcia, EM; García-Campos, C; García-Donas, J; García-Pérez, AL; Gasparri, F; Ge, C; Ge, D; Ge, JB; Ge, X; George, I; George, LA; Germani, G; Ghassemi Tabrizi, S; Gibon, Y; Gillent, E; Gillies, RS; Gilmour, MI; Goble, S; Goh, JC; Goiri, F; Goldfinger, LE; Golian, M; Gómez, MA; Gonçalves, J; Góngora-García, OR; Gonul, I; González, MA; Govers, TM; Grant, PC; Gray, EH; Gray, JE; Green, MS; Greenwald, I; Gregory, MJ; Gretzke, D; Griffin-Nolan, RJ; Griffith, DC; Gruppen, EG; Guaita, A; Guan, P; Guan, X; Guerci, P; Guerrero, DT; Guo, M; Guo, P; Guo, R; Guo, X; Gupta, J; Guz, G; Hajizadeh, N; Hamada, H; Haman-Wabi, AB; Han, TT; Hannan, N; Hao, S; Harjola, VP; Harmon, M; Hartmann, MSM; Hartwig, JF; Hasani, M; Hawthorne, WJ; Haykal-Coates, N; Hazari, MS; He, DL; He, P; He, SG; Héau, C; Hebbar Kannur, K; Helvaci, O; Heuberger, DM; Hidalgo, F; Hilty, MP; Hirata, K; Hirsch, A; Hoffman, AM; Hoffmann, JF; Holloway, RW; Holmes, RK; Hong, S; Hongisto, M; Hopf, NB; Hörlein, R; Hoshino, N; Hou, Y; Hoven, NF; Hsieh, YY; Hsu, CT; Hu, CW; Hu, JH; Hu, MY; Hu, Y; Hu, Z; Huang, C; Huang, D; Huang, DQ; Huang, L; Huang, Q; Huang, R; Huang, S; Huang, SC; Huang, W; Huang, Y; Huffman, KM; Hung, CH; Hung, CT; Huurman, R; Hwang, SM; Hyun, S; Ibrahim, AM; Iddi-Faical, A; Immordino, P; Isla, MI; Jacquemond, V; Jacques, T; Jankowska, E; Jansen, JA; Jäntti, T; Jaque-Fernandez, F; Jarvis, GA; Jatt, LP; Jeon, JW; Jeong, SH; Jhunjhunwala, R; Ji, F; Jia, X; Jia, Y; Jian-Bo, Z; Jiang, GD; Jiang, L; Jiang, W; Jiang, WD; Jiang, Z; Jiménez-Hoyos, CA; Jin, S; Jobling, MG; John, CM; John, T; Johnson, CB; Jones, KI; Jones, WS; Joseph, OO; Ju, C; Judeinstein, P; Junges, A; Junnarkar, M; Jurkko, R; Kaleka, CC; Kamath, AV; Kang, X; Kantsadi, AL; Kapoor, M; Karim, Z; Kashuba, ADM; Kassa, E; Kasztura, M; Kataja, A; Katoh, T; Kaufman, JS; Kaupp, M; Kehinde, O; Kehrenberg, C; Kemper, N; Kerr, CW; Khan, AU; Khan, MF; Khan, ZUH; Khojasteh, SC; Kilburn, S; Kim, CG; Kim, DU; Kim, DY; Kim, HJ; Kim, J; Kim, OH; Kim, YH; King, C; Klein, A; Klingler, L; Knapp, AK; Ko, TK; Kodavanti, UP; Kolla, V; Kong, L; Kong, RY; Kong, X; Kore, S; Kortz, U; Korucu, B; Kovacs, A; Krahnert, I; Kraus, WE; Kuang, SY; Kuehn-Hajder, JE; Kurz, M; Kuśtrowski, P; Kwak, YD; Kyttaris, VC; Laga, SM; Laguerre, A; Laloo, A; Langaro, MC; Langham, MC; Lao, X; Larocca, MC; Lassus, J; Lattimer, TA; Lazar, S; Le, MH; Leal, DB; Leal, M; Leary, A; Ledermann, JA; Lee, JF; Lee, MV; Lee, NH; Leeds, CM; Leeds, JS; Lefrandt, JD; Leicht, AS; Leonard, M; Lev, S; Levy, K; Li, B; Li, C; Li, CM; Li, DH; Li, H; Li, J; Li, L; Li, LJ; Li, N; Li, P; Li, T; Li, X; Li, XH; Li, XQ; Li, XX; Li, Y; Li, Z; Li, ZY; Liao, YF; Lin, CC; Lin, MH; Lin, Y; Ling, Y; Links, TP; Lira-Romero, E; Liu, C; Liu, D; Liu, H; Liu, J; Liu, L; Liu, LP; Liu, M; Liu, T; Liu, W; Liu, X; Liu, XH; Liu, Y; Liuwantara, D; Ljumanovic, N; Lobo, L; Lokhande, K; Lopes, A; Lopes, RMRM; López-Gutiérrez, JC; López-Muñoz, MJ; López-Santamaría, M; Lorenzo, C; Lorusso, D; Losito, I; Lu, C; Lu, H; Lu, HZ; Lu, SH; Lu, SN; Lu, Y; Lu, ZY; Luboga, F; Luo, JJ; Luo, KL; Luo, Y; Lutomski, CA; Lv, W; M Piedade, MF; Ma, J; Ma, JQ; Ma, JX; Ma, N; Ma, P; Ma, S; Maciel, M; Madureira, M; Maganaris, C; Maginn, EJ; Mahnashi, MH; Maierhofer, M; Majetschak, M; Malla, TR; Maloney, L; Mann, DL; Mansuri, A; Marelli, E; Margulis, CJ; Marrella, A; Martin, BL; Martín-Francés, L; Martínez de Pinillos, M; Martínez-Navarro, EM; Martinez-Quintanilla Jimenez, D; Martínez-Velasco, A; Martínez-Villaseñor, L; Martinón-Torres, M; Martins, BA; Massongo, M; Mathew, AP; Mathews, D; Matsui, J; Matsumoto, KI; Mau, T; Maves, RC; Mayclin, SJ; Mayer, JM; Maynard, ND; Mayr, T; Mboowa, MG; McEvoy, MP; McIntyre, RC; McKay, JA; McPhail, MJW; McVeigh, AL; Mebazaa, A; Medici, V; Medina, DN; Mehmood, T; Mei-Li, C; Melku, M; Meloncelli, S; Mendes, GC; Mendoza-Velásquez, C; Mercadante, R; Mercado, MI; Merenda, MEZ; Meunier, J; Mi, SL; Michels, M; Mijatovic, V; Mikhailov, V; Milheiro, SA; Miller, DC; Ming, F; Mitsuishi, M; Miyashita, T; Mo, J; Mo, S; Modesto-Mata, M; Moeller, S; Monte, A; Monteiro, L; Montomoli, J; Moore, EE; Moore, HB; Moore, PK; Mor, MK; Moratalla-López, N; Moratilla Lapeña, L; Moreira, R; Moreno, MA; Mörk, AC; Morton, M; Mosier, JM; Mou, LH; Mougharbel, AS; Muccillo-Baisch, AL; Muñoz-Serrano, AJ; Mustafa, B; Nair, GM; Nakanishi, I; Nakanjako, D; Naraparaju, K; Nawani, N; Neffati, R; Neil, EC; Neilipovitz, D; Neira-Borrajo, I; Nelson, MT; Nery, PB; Nese, M; Nguyen, F; Nguyen, MH; Niazy, AA; Nicolaï, J; Nogueira, F; Norbäck, D; Novaretti, JV; O'Donnell, T; O'Dowd, A; O'Malley, DM; Oaknin, A; Ogata, K; Ohkubo, K; Ojha, M; Olaleye, MT; Olawande, B; Olomo, EJ; Ong, EWY; Ono, A; Onwumere, J; Ortiz Bibriesca, DM; Ou, X; Oza, AM; Ozturk, K; Özütemiz, C; Palacio-Pastrana, C; Palaparthi, A; Palevsky, PM; Pan, K; Pantanetti, S; Papachristou, DJ; Pariani, A; Parikh, CR; Parissis, J; Paroul, N; Parry, S; Patel, N; Patel, SM; Patel, VC; Pawar, S; Pefura-Yone, EW; Peixoto Andrade, BCO; Pelepenko, LE; Peña-Lora, D; Peng, S; Pérez-Moro, OS; Perez-Ortiz, AC; Perry, LM; Peter, CM; Phillips, NJ; Phillips, P; Pia Tek, J; Piner, LW; Pinto, EA; Pinto, SN; Piyachaturawat, P; Poka-Mayap, V; Polledri, E; Poloni, TE; Ponessa, G; Poole, ST; Post, AK; Potter, TM; Pressly, BB; Prouty, MG; Prudêncio, M; Pulkki, K; Pupier, C; Qian, H; Qian, ZP; Qiu, Y; Qu, G; Rahimi, S; Rahman, AU; Ramadan, H; Ramanna, S; Ramirez, I; Randolph, GJ; Rasheed, A; Rault, J; Raviprakash, V; Reale, E; Redpath, C; Rema, V; Remucal, CK; Remy, D; Ren, T; Ribeiro, LB; Riboli, G; Richards, J; Rieger, V; Rieusset, J; Riva, A; Rivabella Maknis, T; Robbins, JL; Robinson, CV; Roche-Campo, F; Rodriguez, R; Rodríguez-de-Cía, J; Rollenhagen, JE; Rosen, EP; Rub, D; Rubin, N; Rubin, NT; Ruurda, JP; Saad, O; Sabell, T; Saber, SE; Sabet, M; Sadek, MM; Saejio, A; Salinas, RM; Saliu, IO; Sande, D; Sang, D; Sangenito, LS; Santos, ALSD; Sarmiento Caldas, MC; Sassaroli, S; Sassi, V; Sato, J; Sauaia, A; Saunders, K; Saunders, PR; Savarino, SJ; Scambia, G; Scanlon, N; Schetinger, MR; Schinkel, AFL; Schladweiler, MC; Schofield, CJ; Schuepbach, RA; Schulz, J; Schwartz, N; Scorcella, C; Seeley, J; Seemann, F; Seinige, D; Sengoku, T; Seravalli, J; Sgromo, B; Shaheen, MY; Shan, L; Shanmugam, S; Shao, H; Sharma, S; Shaw, KJ; Shen, BQ; Shen, CH; Shen, P; Shen, S; Shen, Y; Shen, Z; Shi, J; Shi-Li, L; Shimoda, K; Shoji, Y; Shun, C; Silva, MA; Silva-Cardoso, J; Simas, NK; Simirgiotis, MJ; Sincock, SA; Singh, MP; Sionis, A; Siu, J; Sivieri, EM; Sjerps, MJ; Skoczen, SL; Slabon, A; Slette, IJ; Smith, MD; Smith, S; Smith, TG; Snapp, KS; Snow, SJ; Soares, MCF; Soberman, D; Solares, MD; Soliman, I; Song, J; Sorooshian, A; Sorrell, TC; Spinar, J; Staudt, A; Steinhart, C; Stern, ST; Stevens, DM; Stiers, KM; Stimming, U; Su, YG; Subbian, V; Suga, H; Sukhija-Cohen, A; Suksamrarn, A; Suksen, K; Sun, J; Sun, M; Sun, P; Sun, W; Sun, XF; Sun, Y; Sundell, J; Susan, LF; Sutjarit, N; Swamy, KV; Swisher, EM; Sykes, C; Takahashi, JA; Talmor, DS; Tan, B; Tan, ZK; Tang, L; Tang, S; Tanner, JJ; Tanwar, M; Tarazi, Z; Tarvasmäki, T; Tay, FR; Teketel, A; Temitayo, GI; Thersleff, T; Thiessen Philbrook, H; Thompson, LC; Thongon, N; Tian, B; Tian, F; Tian, Q; Timothy, AT; Tingle, MD; Titze, IR; Tolppanen, H; Tong, W; Toyoda, H; Tronconi, L; Tseng, CH; Tu, H; Tu, YJ; Tung, SY; Turpault, S; Tuynman, JB; Uemoto, AT; Ugurlu, M; Ullah, S; Underwood, RS; Ungell, AL; Usandizaga-Elio, I; Vakonakis, I; van Boxel, GI; van den Beucken, JJJP; van der Boom, T; van Slegtenhorst, MA; Vanni, JR; Vaquera, A; Vasconcellos, RS; Velayos, M; Vena, R; Ventura, G; Verso, MG; Vincent, RP; Vitale, F; Vitali, S; Vlek, SL; Vleugels, MPH; Volkmann, N; Vukelic, M; Wagner Mackenzie, B; Wairagala, P; Waller, SB; Wan, J; Wan, MT; Wan, Y; Wang, CC; Wang, H; Wang, J; Wang, JF; Wang, K; Wang, L; Wang, M; Wang, S; Wang, WM; Wang, X; Wang, Y; Wang, YD; Wang, YF; Wang, Z; Wang, ZG; Warriner, K; Weberpals, JI; Weerachayaphorn, J; Wehrli, FW; Wei, J; Wei, KL; Weinheimer, CJ; Weisbord, SD; Wen, S; Wendel Garcia, PD; Williams, JW; Williams, R; Winkler, C; Wirman, AP; Wong, S; Woods, CM; Wu, B; Wu, C; Wu, F; Wu, P; Wu, S; Wu, Y; Wu, YN; Wu, ZH; Wurtzel, JGT; Xia, L; Xia, Z; Xia, ZZ; Xiao, H; Xie, C; Xin, ZM; Xing, Y; Xing, Z; Xu, S; Xu, SB; Xu, T; Xu, X; Xu, Y; Xue, L; Xun, J; Yaffe, MB; Yalew, A; Yamamoto, S; Yan, D; Yan, H; Yan, S; Yan, X; Yang, AD; Yang, E; Yang, H; Yang, J; Yang, JL; Yang, K; Yang, M; Yang, P; Yang, Q; Yang, S; Yang, W; Yang, X; Yang, Y; Yao, JC; Yao, WL; Yao, Y; Yaqub, TB; Ye, J; Ye, W; Yen, CW; Yeter, HH; Yin, C; Yip, V; Yong-Yi, J; Yu, HJ; Yu, MF; Yu, S; Yu, W; Yu, WW; Yu, X; Yuan, P; Yuan, Q; Yue, XY; Zaia, AA; Zakhary, SY; Zalwango, F; Zamalloa, A; Zamparo, P; Zampini, IC; Zani, JL; Zeitoun, R; Zeng, N; Zenteno, JC; Zepeda-Palacio, C; Zhai, C; Zhang, B; Zhang, G; Zhang, J; Zhang, K; Zhang, Q; Zhang, R; Zhang, T; Zhang, X; Zhang, Y; Zhang, YY; Zhao, B; Zhao, D; Zhao, G; Zhao, H; Zhao, Q; Zhao, R; Zhao, S; Zhao, T; Zhao, X; Zhao, XA; Zhao, Y; Zhao, Z; Zheng, Z; Zhi-Min, G; Zhou, CL; Zhou, HD; Zhou, J; Zhou, W; Zhou, XQ; Zhou, Z; Zhu, C; Zhu, H; Zhu, L; Zhu, Y; Zitzmann, N; Zou, L; Zou, Y | 1 |
| Hiraki, K; Hishida, Y; Kawanabe, S; Nagai, Y; Sone, M; Tanaka, Y; Yamamoto, Y | 1 |
| de Ligt, M; Hesselink, MKC; Hoeks, J; Phielix, E; Schrauwen, P; Vanweert, F | 1 |
| Elovaris, RA; Feinle-Bisset, C; Fitzgerald, PCE; Hajishafiee, M; Horowitz, M; Lange, K; Ullrich, SS | 1 |
| Bongers, A; de Vogel-van den Bosch, J; Memelink, RG; Pasman, WJ; Tromp, W; Tump, A; van Ginkel, A; Verlaan, S; Weijs, PJM; Wopereis, S | 1 |
| Fang, ZZ; Gao, X; Hou, R; Li, X; Liu, SL; Luo, HH; Qiu, XH | 1 |
| Bararpour, N; Darrous, L; Froguel, P; Gasser, M; Gilardi, F; Kutalik, Z; Marques-Vidal, P; Porcu, E; Thomas, A; Waeber, G; Yengo, L | 1 |
| Agah, S; Bitarafan, V; Elovaris, RA; Feinle-Bisset, C; Horowitz, M; Lange, K; Ullrich, SS | 1 |
| Hao, H; Hu, W; Li, J; Li, S; Liu, Z; Lu, Y; Qi, X; Wang, X; Wen, S; Yu, W; Zhou, H | 1 |
| Baum, SJ; Chakravarthy, MV; Chera, H; Gunn, NT; Harrison, SA; Kohli, A; Koziel, MJ; Patil, R; Younes, ZH; Zhao, J | 1 |
| Kolahian, S; Larki, NN; Sadri, H | 1 |
| He, X; Wang, L; Wang, S; Yuan, Y; Zhang, Y; Zhong, J; Zhou, Y | 1 |
| Birech, Z; Bukachi, F; Mandela, KM; Mwangi, PW | 1 |
| Boerwinkle, E; Chang, P; Coresh, J; Köttgen, A; Rebholz, CM; Selvin, E; Tin, A; Wagenknecht, LE; Yu, B; Zheng, Z | 1 |
| He, T; Ma, X; Nie, C; Zhang, G; Zhang, W | 1 |
| Al-Majdoub, M; Ali, A; Carstensen, B; Ridderstråle, M; Safai, N; Spégel, P; Suvitaival, T; Vestergaard, H | 1 |
| Afolabi, PR; Almehmadi, AA; Byrne, CD; Calder, PC; Scorletti, E; Smith, DE | 1 |
| Brunetta, HS; de Camargo, CQ; Nunes, EA | 1 |
| Borodulin, K; Hagnäs, M; Jauhiainen, M; Joensuu, A; Jokelainen, JJ; Jousilahti, P; Keinänen-Kiukaanniemi, S; Kettunen, J; Lee, JH; Mikkola, I; Perola, M; Terwilliger, JD; Wennerström, A | 1 |
| Biebermann, H; Gong, M; Homuth, G; Jacobi, SF; Khajavi, N; Kleinau, G; Krude, H; Kühnen, P; Raile, K; Scheerer, P; Teumer, A; Völzke, H; Wiegand, S | 1 |
| Kuusisto, J; Laakso, M; Smith, U; Stancáková, A; Vangipurapu, J | 1 |
| Arab-Bafrani, Z; Hashemi, MM; Marjani, A; Mousavi, E; Nezhadebrahimi, A | 1 |
| Feng, Y; Geng, X; Jia, W; Jiang, Z; Li, F; Lu, H; Wang, C; Wei, X; Yan, J; Zhang, Y | 1 |
| Chen, HY; Chen, KH; Huang, CH; Huang, YY; Hung, SY; Lin, CN; Lin, CW; Tsai, JS; Yang, HM; Yeh, JT | 1 |
| Berman, DE; Leibel, RL; Morabito, MV; Schneider, RT; Small, SA; Zhang, Y | 1 |
| Alkhalaf, A; Bakker, SJ; Bilo, HJ; De Heer, E; Gans, RO; Groenier, KH; Kleefstra, N; Landman, GW; Mooyaart, AL; Navis, GJ; van Hateren, KJ | 1 |
| Chevalier, S; Gougeon, R; Labonte, CC; Marliss, EB; Morais, JA | 1 |
| Amani, M; Kolahian, S; Mazadeh, A; Mirani, M; Sadri, H; Shahbazfar, AA | 1 |
| Barazzoni, R; Cortella, I; Gabelli, C; Kiwanuka, E; Manesso, E; Pasqualetto, G; Puricelli, L; Tessari, P; Toffolo, GM; Vettore, M; Zanetti, M | 1 |
| Bao, Y; Chen, T; Hu, C; Huang, F; Jia, W; Liu, J; Ma, X; Ni, Y; Xie, G; Zhao, A | 1 |
| Burd, NA; Cermak, NM; Churchward-Venne, TA; Gijsen, AP; Kouw, IW; Senden, JM; van Loon, LJ | 1 |
| Adamski, J; Beyerlein, A; Herbst, M; Hivner, S; Hofelich, A; Hummel, S; Kastenmüller, G; Kindt, A; Krumsiek, J; Much, D; Prehn, C; Römisch-Margl, W; Rossbauer, M; Stückler, F; Theis, F; Wiesenäcker, D; Ziegler, AG | 1 |
| Bao, Y; Chen, T; Hu, C; Huang, F; Jia, W; Ma, X; Ni, Y; Rajani, C; Zhao, A; Zheng, X | 1 |
| Jin, AL; Xie, XR; Yang, YM | 1 |
| Babraj, J; Cuthbertson, DJ; Leese, G; Siervo, M | 1 |
| Han, JY; Jee, SH; Kim, M; Lee, JH; Lee, SH | 1 |
| Boehm, BO; Fritsche, A; Häring, HU; Hoffmann, MM; Machann, J; Machicao-Arano, F; März, W; Schick, F; Silbernagel, G; Stefan, N; Winkelmann, BR | 1 |
| Berthold, HK; Giannakidou, E; Gouni-Berthold, I; Krone, W; Mantzoros, CS | 1 |
| Chen, X; Dong, Y; Feng, Q; Su, Q; Wang, X; Zhang, H | 1 |
| Crowley, VE; DeLong, C; Hand, E; Hatunic, M; Nolan, JJ; Stapleton, M | 1 |
| Cline, GW; Kibbey, RG; Kirkpatrick, CL; Pongratz, RL; Pontoglio, M; Shulman, GI; Wollheim, CB; Yaniv, M; Zhao, X | 1 |
| Chen, W; Hang, W; Huang, B; Lin, L; Song, X; Yan, L; Yan, X; Zhang, J | 1 |
| Araújo, EP; Batista, TM; Boschero, AC; Carneiro, EM; Curi, R; Filiputti, E; Quesada, I; Rafacho, A; Silveira, LR; Trevisan, A; Velloso, LA | 1 |
| Baelde, HJ; Bakker, SJ; Bilo, HJ; Böhringer, S; Bruijn, JA; De Heer, E; Dekker, FW; Grootendorst, DC; Janssen, B; Kleefstra, N; Mooyaart, AL; Navis, G; van Valkengoed, IG; Zutinic, A | 1 |
| Burkhardt, BR; Chi, Y; Guan, Y; Wolf, BA; Yang, J | 1 |
| Carneiro, EM; de Mello, MA; de Oliveira, CA; Latorraca, MQ | 1 |
| Grasso, DM; La Rosa, C; Milardi, D; Pappalardo, M; Sciacca, MF | 1 |
| Hanaoka, K; Kawaguchi, M; Kojima, H; Minegishi, I; Nagano, T; Okabe, T; Terai, T | 1 |
| Hartgens, F; Leenders, M; Saris, WH; van der Hoeven, L; van Kranenburg, J; van Loon, LJ; Verdijk, LB; Wodzig, WK | 1 |
| Adiels, M; Berglund, M; Jirstrand, M; Sunnåker, M; Wennberg, B | 1 |
| Leenders, M; van Loon, LJ | 1 |
| van Loon, LJ | 1 |
| Burggraaf, J; Cohen, AF; de Kam, ML; Flameling, B; Geerts, BF; Gerhardt, CC; Kloek, J; Moerland, MM; Romijn, JA; van Dongen, MG | 1 |
| Bing, YJ; Liu, J; Liu, JX; Tian, LM; Wang, YF; Zhang, JP; Zhang, LY | 1 |
| Clish, CB; Deik, AA; Fleischman, A; Gerszten, RE; Grinspoon, SK; McCarthy, MA; McCormack, SE; Mootha, VK; Shaham, O; Wang, TJ | 1 |
| Bassil, MS; Gougeon, R | 1 |
| Candow, DG; Forbes, SC; Little, JP; Manders, RJ | 1 |
| Raleigh, DP; Tu, LH | 1 |
| Bigelow, M; Halvatsiotis, P; Nair, KS; Short, KR | 1 |
| Alzaid, A; Dinneen, S; Halvatsiotis, PG; Nair, KS; Rizza, RA; Turk, D | 1 |
| D'Alfonso, R; Federici, M; Frittitta, L; Frontoni, S; Gambardella, S; Lauro, D; Lauro, R; Mariani, LM; Marini, MA; Porzio, O; Sesti, G; Sorge, R; Trischitta, V | 1 |
| Keizer, HA; Kruijshoop, M; Menheere, PP; Saris, WH; van Loon, LJ; Wagenmakers, AJ | 1 |
| Chang, I; Chi, YI; Kang, K; Kim, KA; Kim, KW; Lee, MK; Lee, MS; Shoelson, SE | 1 |
| Huang, Z; Sui, Y; Weng, J; Xiu, L; Yan, J | 1 |
| Epe, M; Fehmann, HC; Gross, U | 1 |
| Dou, H; Li, KS; Mao, JF; Yang, SS; Zhang, ZZ | 1 |
| Battezzati, A; Benedini, S; Costantino, F; Lattuada, G; Luzi, L; Perseghin, G; Ragogna, F; Ruggieri, D; Scollo, A; Sereni, LP | 1 |
| Cucuianu, M; Dican, L | 1 |
| Carli, F; Carvalho, G; Eberhart, L; Gougeon, R; Mazza, L; Schricker, T; Wykes, L | 1 |
| Kawabe, M; Sakaue, M; Taniguchi, H | 1 |
| Brismar, K; Ding, B; Efendic, S; Gu, HF; Kärvestedt, L; Nordman, S; Ostenson, CG | 1 |
| Furuta, H; Hanabusa, T; Nakagawa, T; Nanjo, K; Nishi, M; Sakagashira, S; Sanke, T; Sasaki, H; Shimajiri, Y; Shimomura, H | 1 |
| Adiels, M; Borén, J; Caslake, MJ; Olofsson, SO; Packard, C; Soro, A; Stewart, P; Taskinen, MR; Wennberg, B; Westerbacka, J | 1 |
| Koopman, R; Manders, RJ; Menheere, PP; Saris, WH; Schaper, NC; van Loon, LJ; Wagenmakers, AJ; Zorenc, AH | 1 |
| Baelde, H; Bakker, SJ; Bartram, CR; Brinkkoetter, P; Cerna, M; de Heer, E; Fischer, C; Hammes, HP; Hohenadel, D; Janssen, B; Köppel, H; Mathieson, P; Meyer, J; Nawroth, P; Peters, V; Rind, N; Romzova, M; Rondeau, E; Rychlik, I; Saleem, MA; Sauerhoefer, S; van der Woude, FJ; Yard, BA; Zirie, M; Zschocke, J | 1 |
| Kandror, KV; Tzatsos, A | 1 |
| Cook, JR; Deng, S; Gao, Z; Markmann, J; Naji, A; Park, M; Wolf, BA; Wong, RK; Wu, J; Yang, J; York, DA | 1 |
| Barazzoni, R; Carnielli, V; Cogo, P; Gucciardi, A; Kiwanuka, E; Millioni, R; Puricelli, L; Tessari, P; Tiengo, A; Tosolini, M; Vettore, M; Zanetti, M | 1 |
| Koopman, R; Manders, RJ; Saris, WH; Sluijsmans, WE; van den Berg, R; van Loon, LJ; Verbeek, K; Wagenmakers, AJ | 1 |
| de Roos, AL; Koopman, R; Manders, RJ; Meex, RC; Praet, SF; Saris, WH; van Loon, LJ; Wagenmakers, AJ | 1 |
| Bowden, DW; Freedman, BI; Hicks, PJ; Janssen, B; Langefeld, CD; McDonough, C; Pierson, ED; Rich, SS; Sale, MM; van der Woude, FJ; Xu, J; Yard, BA | 1 |
| Kesäniemi, YA; Ukkola, O | 1 |
| Jaakkola, U; Kallio, J; Karvonen, MK; Koulu, M; Pesonen, U; Seppälä, H; Vahlberg, T | 1 |
| Manders, RJ; Praet, SF; Saris, WH; van Loon, LJ; Vikström, MH | 1 |
| Chevalier, S; Gougeon, R; Marliss, EB; Morais, JA; Pereira, S | 1 |
| Castellino, P; Ciarambino, T; Cioffi, M; De Feo, P; Gesuè, L; Giordano, M; Gresele, P; Lucidi, P; Paolisso, G | 1 |
| Bergeron, J; Couture, P; Deshaies, Y; Gagné, C; Hogue, JC; Lamarche, B; Tremblay, AJ | 1 |
| Carli, F; Donatelli, F; Lugli, AK; Schricker, T; Wykes, L | 1 |
| Awata, T; Goto, Y; Kadowaki, H; Kadowaki, T; Mori, Y; Sakura, H; Sakuta, R; Suzuki, Y; Tanabe, Y; Tobe, K | 1 |
| De Fronzo, RA; Luzi, L; Petrides, AS | 1 |
| Keller, U; Laager, R | 1 |
| Blanché, H; Dussoix, P; Froguel, P; Garin, MC; James, RW; Passa, P; Ruiz, J | 1 |
| Bedford, D; Caslake, M; Malmström, R; Packard, CJ; Shepherd, J; Stewart, P; Taskinen, MR; Yki-Järvinen, H | 1 |
| Frénais, R; Krempf, M; Magot, T; Mahot, P; Maugeais, C; Maugère, P; Ouguerram, K | 1 |
| Boland, O; Matthews, DR | 1 |
| Bannister, PA; Chrisoulidou, A; Gallager, JJ; Gray, RM; Johnston, DG; Robinson, AC; Venkatesan, S | 1 |
| Abdel-Halim, SM; Efendic, S; Khan, A; Landau, BR; Ling, ZC; Ostenson, CG; Wibom, R | 1 |
| Clausen, JO; Eiberg, H; Ekstrøm, CT; Hansen, T; Møller, AM; Nyholm, B; Pedersen, O; Schmitz, O; Urhammer, SA | 1 |
| Giroix, MH; Portha, B; Saulnier, C | 1 |
| Duvillard, L; Florentin, E; Gambert, P; Pont, F; Vergès, B | 1 |
| Karvonen, MK; Koulu, M; Laakso, M; Mercuri, M; Niskanen, L; Pesonen, U; Rauramaa, R; Töyry, J; Uusitupa, MI; Valve, R | 1 |
| Karvonen, MK; Koulu, M; Laakso, M; Niskanen, L; Pesonen, U; Teräsvirta, M; Uusitupa, MI; Valve, R; Voutilainen-Kaunisto, R | 1 |
| Duvillard, L; Florentin, E; Galland-Jos, C; Gambert, P; Pont, F; Vergès, B | 1 |
| Barazzoni, R; Carraro, P; Davanzo, G; Kiwanuka, E; Tessari, P; Tiengo, A; Zanetti, M | 1 |
| Broyart, JP; Gray, GM; Hampp, LT; Najjar, SM | 1 |
| Bjørkhaug, L; Horikawa, Y; Molven, A; Njølstad, PR; Søvik, O; Ye, H | 1 |
| Bailbe, D; Gangnerau, MN; Giroix, MH; Marie, JC; Mithieux, G; Movassat, J; Plachot, C; Portha, B; Rajas, F; Serradas, P | 1 |
| Gong, JS; Kawamori, R; Matsunaga, H; Nomiyama, T; Ogawa, O; Ogihara, T; Tanaka, M; Tanaka, Y; Yagi, K; Yamada, Y; Zhang, J | 1 |
| Hashiramoto, M; Iwamoto, K; Kasuga, M; Maeda, E; Mori, H; Okazawa, H | 1 |
| Biondi, RM; Cohen, P; Frame, S | 1 |
| Richardson, AP; Tayek, JA | 1 |
| Inoue, Y; Iwasaki, R; Kuhara, T; Matsumoto, I; Morimoto, S; Yu, WM | 1 |
| Nair, KS; Welle, S | 1 |
| Boroujerdi, MA; Carson, ER; Scobie, IN; Sonksen, PH; Umpleby, AM | 1 |
| Atkinson, S; Caro, JF; Flickinger, EG; Meelheim, D; Pories, WJ; Sehgal, NS; Sinha, MK; Taylor, LG | 1 |
| Bier, DM; Matthews, DE; Staten, MA | 1 |
17 review(s) available for leucine and Diabetes Mellitus, Adult-Onset
| Article | Year |
|---|---|
Role of Branched-Chain Amino Acid Metabolism in Type 2 Diabetes, Obesity, Cardiovascular Disease and Non-Alcoholic Fatty Liver Disease.
Topics: Amino Acids, Branched-Chain; Animals; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Humans; Leucine; Mammals; Metabolic Diseases; Non-alcoholic Fatty Liver Disease; Obesity | 2022 |
Branched-chain amino acids as a novel biomarker of metabolic disturbances in women with polycystic ovary syndrome - literature review.
Topics: Amino Acids, Branched-Chain; Animals; Biomarkers; Diabetes Mellitus, Type 2; Female; Humans; Insulin Resistance; Isoleucine; Leucine; Obesity; Polycystic Ovary Syndrome; Prediabetic State; Valine | 2022 |
The Association between Circulating Branched Chain Amino Acids and the Temporal Risk of Developing Type 2 Diabetes Mellitus: A Systematic Review & Meta-Analysis.
Topics: Amino Acids, Branched-Chain; Biomarkers; Diabetes Mellitus, Type 2; Humans; Isoleucine; Leucine; Valine | 2022 |
Regulation of Skeletal Muscle Function by Amino Acids, Especially Non-Proteinogenic Amino Acids.
Topics: Aged; Amino Acids; Animals; beta-Alanine; Diabetes Mellitus, Type 2; Humans; Leucine; Mammals; Mice; Middle Aged; Muscle, Skeletal | 2022 |
Branched-Chain Amino Acids and Insulin Resistance, from Protein Supply to Diet-Induced Obesity.
Topics: Amino Acids, Branched-Chain; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Diet; Insulin; Insulin Resistance; Leucine; Obesity | 2022 |
Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain; Acyclic Monoterpenes; Adenine Nucleotides; Adhesins, Escherichia coli; Adipocytes; Adipocytes, Brown; Adipogenesis; Administration, Inhalation; Administration, Oral; Adrenal Cortex Hormones; Adsorption; Adult; Aeromonas hydrophila; Africa; Aged; Aged, 80 and over; Agrobacterium tumefaciens; Air; Air Pollutants; Air Pollution; Air Pollution, Indoor; Algorithms; Alkaloids; Alkynes; Allosteric Regulation; Amines; Amino Acid Sequence; Amino Acids; Amino Acids, Branched-Chain; Aminoisobutyric Acids; Aminopyridines; Amyotrophic Lateral Sclerosis; Anaerobic Threshold; Angiography; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animal Distribution; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Ankle Joint; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Inflammatory Agents; Antibodies, Bacterial; Antifungal Agents; Antimalarials; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Antiretroviral Therapy, Highly Active; Antiviral Agents; Aotidae; Apelin; Apoptosis; Arabidopsis Proteins; Argentina; Arginine; Artemisinins; Arthritis, Experimental; Arthritis, Rheumatoid; Arthroscopy; Aspergillus; Aspergillus niger; Asteraceae; Asthma; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; Auditory Cortex; Autoantibodies; Autophagy; Bacteria; Bacterial Infections; Bacterial Proteins; Bacterial Typing Techniques; Base Composition; Base Sequence; Basketball; Beclin-1; Benzhydryl Compounds; Benzimidazoles; Benzo(a)pyrene; Benzofurans; Benzoxazines; Bereavement; beta Catenin; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Betacoronavirus; Betaine; Binding Sites; Biofilms; Biological Assay; Biological Availability; Biological Evolution; Biomarkers; Biomechanical Phenomena; Biopolymers; Biopsy; Bismuth; Blood Glucose; Blood Platelets; Blood Pressure; Body Composition; Body Weight; Bone Marrow; Bone Marrow Cells; Bone Regeneration; Boron; Botrytis; Brain Ischemia; Brain Neoplasms; Brain-Derived Neurotrophic Factor; Brazil; Breast Neoplasms; Breath Tests; Bronchoalveolar Lavage Fluid; Burkholderia; C-Reactive Protein; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Calcification, Physiologic; Calcium; Calcium Signaling; Calorimetry, Differential Scanning; Cameroon; Camptothecin; Candida; Candida albicans; Capillaries; Carbapenem-Resistant Enterobacteriaceae; Carbapenems; Carbohydrate Conformation; Carbon; Carbon Dioxide; Carbon Isotopes; Carcinoma, Ovarian Epithelial; Cardiac Output; Cardiomyopathy, Hypertrophic; Cardiotonic Agents; Cardiovascular Diseases; Caregivers; Carps; Case-Control Studies; Catalase; Catalysis; Cats; CD4 Lymphocyte Count; Cell Culture Techniques; Cell Differentiation; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Cellulose; Centrosome; Ceratopogonidae; Chickens; Child; China; Cholera Toxin; Choline; Cholinesterases; Chromatography, High Pressure Liquid; Chromatography, Liquid; Chromatography, Micellar Electrokinetic Capillary; Chromatography, Reverse-Phase; Chronic Disease; Cinnamates; Cities; Citrates; Climate Change; Clinical Trials, Phase III as Topic; Coal; Coal Mining; Cohort Studies; Coinfection; Colchicine; Colony Count, Microbial; Colorectal Neoplasms; Coloring Agents; Common Cold; Complement Factor H; Computational Biology; Computer Simulation; Continuous Positive Airway Pressure; Contrast Media; Coordination Complexes; Coronary Artery Bypass; Coronavirus 3C Proteases; Coronavirus Infections; Coronavirus Protease Inhibitors; Corynebacterium glutamicum; Cosmetics; COVID-19; Creatinine; Cross-Sectional Studies; Crotonates; Crystallography, X-Ray; Cues; Culicidae; Culture Media; Curcuma; Cyclopentanes; Cyclopropanes; Cymbopogon; Cystine; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C19 Inhibitors; Cytokines; Databases, Genetic; Death; Dendritic Cells; Density Functional Theory; Depsides; Diabetes Mellitus, Type 2; Diamond; Diarylheptanoids; Dibenzofurans; Dibenzofurans, Polychlorinated; Diclofenac; Diet; Dietary Carbohydrates; Dietary Supplements; Diffusion Magnetic Resonance Imaging; Dioxins; Diphenylamine; Disease Outbreaks; Disease Susceptibility; Disulfides; Dithiothreitol; Dizocilpine Maleate; DNA Methylation; DNA-Binding Proteins; DNA, Bacterial; Dogs; Dose-Response Relationship, Drug; Double-Blind Method; Doublecortin Protein; Drosophila melanogaster; Droughts; Drug Carriers; Drug Combinations; Drug Delivery Systems; Drug Liberation; Drug Resistance; Drug Resistance, Bacterial; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Dust; Dynactin Complex; Dysferlin; Echo-Planar Imaging; Echocardiography; Edaravone; Egypt; Elasticity; Electrodes; Electrolytes; Emodin; Emtricitabine; Endometriosis; Endothelium, Vascular; Endotoxins; Energy Metabolism; Energy Transfer; Enterobacteriaceae; Enterococcus faecalis; Enterotoxigenic Escherichia coli; Environmental Monitoring; Enzyme Inhibitors; Epidemiologic Factors; Epigenesis, Genetic; Erythrocytes; Escherichia coli; Escherichia coli Infections; Escherichia coli Vaccines; Esophageal Neoplasms; Esophagectomy; Esophagogastric Junction; Esterases; Esterification; Ethanol; Ethiopia; Ethnicity; Eucalyptus; Evidence-Based Practice; Exercise; Exercise Tolerance; Extracorporeal Membrane Oxygenation; Family; Fatty Acids; Feedback; Female; Ferric Compounds; Fibrin Fibrinogen Degradation Products; Filtration; Fish Diseases; Flavonoids; Flavonols; Fluorodeoxyglucose F18; Follow-Up Studies; Food Microbiology; Food Preservation; Forests; Fossils; Free Radical Scavengers; Freund's Adjuvant; Fruit; Fungi; Gallium; Gender Identity; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Genes, Bacterial; Genes, Plant; Genetic Predisposition to Disease; Genitalia; Genotype; Glomerulonephritis, IGA; Glottis; Glucocorticoids; Glucose; Glucuronides; Glutathione Transferase; Glycogen Synthase Kinase 3 beta; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Grassland; Guinea Pigs; Half-Life; Head Kidney; Heart Atria; Heart Rate; Heart Septum; HEK293 Cells; Hematopoietic Stem Cells; Hemodynamics; Hep G2 Cells; Hepacivirus; Hepatitis C; Hepatitis C, Chronic; Hepatocytes; Hesperidin; High-Frequency Ventilation; High-Temperature Requirement A Serine Peptidase 1; Hippocampus; Hirudins; History, 20th Century; History, 21st Century; HIV Infections; Homeostasis; Hominidae; Housing, Animal; Humans; Hydrocarbons, Brominated; Hydrogen Bonding; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxybutyrates; Hydroxyl Radical; Hypertension; Hypothyroidism; Image Interpretation, Computer-Assisted; Immunoconjugates; Immunogenic Cell Death; Indoles; Infant, Newborn; Infant, Premature; Infarction, Middle Cerebral Artery; Inflammation; Inflammation Mediators; Infrared Rays; Inhibitory Concentration 50; Injections, Intravenous; Interferon-gamma; Interleukin-23; Interleukin-4; Interleukin-6; Intermediate Filaments; Intermittent Claudication; Intestine, Small; Iridoid Glucosides; Iridoids; Iron; Isomerism; Isotope Labeling; Isoxazoles; Itraconazole; Kelch-Like ECH-Associated Protein 1; Ketoprofen; Kidney Failure, Chronic; Kinetics; Klebsiella pneumoniae; Lactams, Macrocyclic; Lactobacillus; Lactulose; Lakes; Lamivudine; Laparoscopy; Laparotomy; Laryngoscopy; Leucine; Limit of Detection; Linear Models; Lipid A; Lipopolysaccharides; Listeria monocytogenes; Liver; Liver Cirrhosis; Logistic Models; Longitudinal Studies; Losartan; Low Back Pain; Lung; Lupinus; Lupus Erythematosus, Systemic; Machine Learning; Macular Degeneration; Madin Darby Canine Kidney Cells; Magnetic Phenomena; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Magnetics; Malaria, Falciparum; Male; Mannans; MAP Kinase Signaling System; Mass Spectrometry; Melatonin; Membrane Glycoproteins; Membrane Proteins; Meniscectomy; Menisci, Tibial; Mephenytoin; Mesenchymal Stem Cells; Metal Nanoparticles; Metal-Organic Frameworks; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; Mice, Obese; Mice, Transgenic; Microbial Sensitivity Tests; Microcirculation; MicroRNAs; Microscopy, Video; Microtubules; Microvascular Density; Microwaves; Middle Aged; Minimally Invasive Surgical Procedures; Models, Animal; Models, Biological; Models, Molecular; Models, Theoretical; Molecular Docking Simulation; Molecular Structure; Molecular Weight; Morus; Mouth Floor; Multicenter Studies as Topic; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Muscle, Skeletal; Myocardial Ischemia; Myocardium; NAD; NADP; Nanocomposites; Nanoparticles; Naphthols; Nasal Lavage Fluid; Nasal Mucosa; Neisseria meningitidis; Neoadjuvant Therapy; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasms, Experimental; Neural Stem Cells; Neuroblastoma; Neurofilament Proteins; Neurogenesis; Neurons; New York; NF-E2-Related Factor 2; NF-kappa B; Nicotine; Nitriles; Nitrogen; Nitrogen Fixation; North America; Observer Variation; Occupational Exposure; Ochrobactrum; Oils, Volatile; Olea; Oligosaccharides; Omeprazole; Open Field Test; Optimism; Oregon; Oryzias; Osmolar Concentration; Osteoarthritis; Osteoblasts; Osteogenesis; Ovarian Neoplasms; Ovariectomy; Oxadiazoles; Oxidation-Reduction; Oxidative Stress; Oxygen; Ozone; p38 Mitogen-Activated Protein Kinases; Pakistan; Pandemics; Particle Size; Particulate Matter; Patient-Centered Care; Pelargonium; Peptides; Perception; Peripheral Arterial Disease; Peroxides; Pets; Pharmaceutical Preparations; Pharmacogenetics; Phenobarbital; Phenols; Phenotype; Phosphates; Phosphatidylethanolamines; Phosphines; Phospholipids; Phosphorus; Phosphorylation; Photoacoustic Techniques; Photochemotherapy; Photosensitizing Agents; Phylogeny; Phytoestrogens; Pilot Projects; Plant Components, Aerial; Plant Extracts; Plant Immunity; Plant Leaves; Plant Oils; Plants, Medicinal; Plasmodium berghei; Plasmodium falciparum; Platelet Activation; Platelet Function Tests; Pneumonia, Viral; Poaceae; Pogostemon; Poloxamer; Poly I; Poly(ADP-ribose) Polymerase Inhibitors; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Polycyclic Compounds; Polyethylene Glycols; Polylysine; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Population Dynamics; Portasystemic Shunt, Transjugular Intrahepatic; Positron Emission Tomography Computed Tomography; Postoperative Complications; Postprandial Period; Potassium Cyanide; Predictive Value of Tests; Prefrontal Cortex; Pregnancy; Prepulse Inhibition; Prevalence; Procalcitonin; Prodrugs; Prognosis; Progression-Free Survival; Proline; Proof of Concept Study; Prospective Studies; Protein Binding; Protein Conformation; Protein Domains; Protein Folding; Protein Multimerization; Protein Sorting Signals; Protein Structure, Secondary; Proton Pump Inhibitors; Protozoan Proteins; Psychometrics; Pulse Wave Analysis; Pyridines; Pyrrolidines; Quality of Life; Quantum Dots; Quinoxalines; Quorum Sensing; Radiopharmaceuticals; Rain; Random Allocation; Randomized Controlled Trials as Topic; Rats; Rats, Sprague-Dawley; Rats, Wistar; RAW 264.7 Cells; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptor, PAR-1; Receptors, CXCR4; Receptors, Estrogen; Receptors, Glucocorticoid; Receptors, Interleukin-1; Receptors, Interleukin-17; Receptors, Notch; Recombinant Fusion Proteins; Recombinant Proteins; Reducing Agents; Reflex, Startle; Regional Blood Flow; Regression Analysis; Reperfusion Injury; Reproducibility of Results; Republic of Korea; Respiratory Tract Diseases; Retrospective Studies; Reverse Transcriptase Inhibitors; Rhinitis, Allergic; Risk Assessment; Risk Factors; Rituximab; RNA, Messenger; RNA, Ribosomal, 16S; ROC Curve; Rosmarinic Acid; Running; Ruthenium; Rutin; Sarcolemma; Sarcoma; Sarcopenia; Sarcoplasmic Reticulum; SARS-CoV-2; Scavenger Receptors, Class A; Schools; Seasons; Seeds; Sequence Analysis, DNA; Severity of Illness Index; Sex Factors; Shock, Cardiogenic; Short Chain Dehydrogenase-Reductases; Signal Transduction; Silver; Singlet Oxygen; Sinusitis; Skin; Skin Absorption; Small Molecule Libraries; Smoke; Socioeconomic Factors; Soil; Soil Microbiology; Solid Phase Extraction; Solubility; Solvents; Spain; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared; Speech; Speech Perception; Spindle Poles; Spleen; Sporothrix; Staphylococcal Infections; Staphylococcus aureus; Stereoisomerism; Stomach Neoplasms; Stress, Physiological; Stroke Volume; Structure-Activity Relationship; Substrate Specificity; Sulfonamides; Surface Properties; Surface-Active Agents; Surveys and Questionnaires; Survival Rate; T-Lymphocytes, Cytotoxic; Tandem Mass Spectrometry; Temperature; Tenofovir; Terpenes; Tetracycline; Tetrapleura; Textiles; Thermodynamics; Thiobarbituric Acid Reactive Substances; Thrombin; Thyroid Hormones; Thyroid Neoplasms; Tibial Meniscus Injuries; Time Factors; Tissue Distribution; Titanium; Toluidines; Tomography, X-Ray Computed; Tooth; Tramadol; Transcription Factor AP-1; Transcription, Genetic; Transfection; Transgender Persons; Translations; Treatment Outcome; Triglycerides; Ubiquinone; Ubiquitin-Specific Proteases; United Kingdom; United States; Up-Regulation; Vascular Stiffness; Veins; Ventricular Remodeling; Viral Load; Virulence Factors; Virus Replication; Vitis; Voice; Voice Quality; Wastewater; Water; Water Pollutants, Chemical; Water-Electrolyte Balance; Weather; Wildfires; Wnt Signaling Pathway; Wound Healing; X-Ray Diffraction; Xenograft Model Antitumor Assays; Young Adult; Zoogloea | 2022 |
Branched Chain Amino Acids: Beyond Nutrition Metabolism.
Topics: Amino Acids, Branched-Chain; Animals; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Isoleucine; Leucine; Metabolic Diseases; Signal Transduction; Valine | 2018 |
Does L-leucine supplementation cause any effect on glucose homeostasis in rodent models of glucose intolerance? A systematic review.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Dietary Supplements; Disease Models, Animal; Glucose Intolerance; Homeostasis; Humans; Insulin; Leucine; Mice, Obese; Obesity; Rodentia | 2018 |
The most effective polymorphisms of paraoxonase-1 gene on enzyme activity and concentration of paraoxonase-1 protein in type 2 diabetes mellitus patients and non-diabetic individuals: A systematic review and meta-analysis.
Topics: Amino Acid Substitution; Arginine; Aryldialkylphosphatase; Diabetes Mellitus, Type 2; Enzyme Activation; Female; Gain of Function Mutation; Genotype; Glutamic Acid; Humans; Leucine; Male; Methionine; Polymorphism, Genetic | 2019 |
Leucine metabolism in regulation of insulin secretion from pancreatic beta cells.
Topics: Animals; Diabetes Mellitus, Type 2; Gene Expression Regulation; Humans; Insulin; Insulin Secretion; Insulin-Secreting Cells; Leucine | 2010 |
Mechanisms of insulin secretion in malnutrition: modulation by amino acids in rodent models.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Animals; Diabetes Mellitus, Type 2; Dietary Supplements; Disease Models, Animal; Gene Expression Regulation; Glucose; Insulin; Insulin Secretion; Insulin-Secreting Cells; Islets of Langerhans; Leucine; Malnutrition; Mice; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Rodentia; Taurine; TOR Serine-Threonine Kinases | 2011 |
Leucine as a pharmaconutrient to prevent and treat sarcopenia and type 2 diabetes.
Topics: Adult; Aged; Aging; Animals; Diabetes Mellitus, Type 2; Dietary Supplements; Humans; Insulin; Insulin Secretion; Insulin-Secreting Cells; Leucine; Muscle Proteins; Muscle Strength; Protein Biosynthesis; Sarcopenia; Up-Regulation | 2011 |
Leucine as a pharmaconutrient in health and disease.
Topics: Amino Acids; Blood Glucose; Diabetes Mellitus, Type 2; Dietary Supplements; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Leucine; Muscle Proteins; Protein Biosynthesis; RNA, Messenger; Sarcopenia | 2012 |
Muscle protein anabolism in type 2 diabetes.
Topics: Aged; Aging; Amino Acids, Branched-Chain; Diabetes Mellitus, Type 2; Dietary Supplements; Humans; Hyperglycemia; Insulin; Insulin Resistance; Leucine; Male; Motor Activity; Muscle Proteins; Muscle Strength; Muscle, Skeletal; Obesity; Protein Biosynthesis; Sarcopenia | 2013 |
Insulinotropic and muscle protein synthetic effects of branched-chain amino acids: potential therapy for type 2 diabetes and sarcopenia.
Topics: Aging; Amino Acids, Branched-Chain; Blood Glucose; Diabetes Mellitus, Type 2; Humans; Insulin; Insulin Resistance; Insulin Secretion; Leucine; Muscle Proteins; Muscle, Skeletal; Sarcopenia | 2012 |
Coagulation factor XIII and atherothrombosis. A mini-review.
Topics: Arteriosclerosis; Diabetes Mellitus, Type 2; Factor XIII; Fibrinolysis; Humans; Insulin Resistance; Leucine; Metabolic Syndrome; Polymorphism, Genetic; Valine | 2003 |
[Polymorphisms of uncoupling protein-1 gene in type 2 diabetes].
Topics: 5' Untranslated Regions; Alleles; Amino Acid Substitution; Animals; Carrier Proteins; Diabetes Mellitus, Type 2; Genetic Predisposition to Disease; Humans; Ion Channels; Leucine; Membrane Proteins; Methionine; Mitochondrial Proteins; Mutation, Missense; Polymorphism, Genetic; Promoter Regions, Genetic; Uncoupling Protein 1 | 2005 |
20 trial(s) available for leucine and Diabetes Mellitus, Adult-Onset
| Article | Year |
|---|---|
Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain; Acyclic Monoterpenes; Adenine Nucleotides; Adhesins, Escherichia coli; Adipocytes; Adipocytes, Brown; Adipogenesis; Administration, Inhalation; Administration, Oral; Adrenal Cortex Hormones; Adsorption; Adult; Aeromonas hydrophila; Africa; Aged; Aged, 80 and over; Agrobacterium tumefaciens; Air; Air Pollutants; Air Pollution; Air Pollution, Indoor; Algorithms; Alkaloids; Alkynes; Allosteric Regulation; Amines; Amino Acid Sequence; Amino Acids; Amino Acids, Branched-Chain; Aminoisobutyric Acids; Aminopyridines; Amyotrophic Lateral Sclerosis; Anaerobic Threshold; Angiography; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animal Distribution; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Ankle Joint; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Inflammatory Agents; Antibodies, Bacterial; Antifungal Agents; Antimalarials; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Antiretroviral Therapy, Highly Active; Antiviral Agents; Aotidae; Apelin; Apoptosis; Arabidopsis Proteins; Argentina; Arginine; Artemisinins; Arthritis, Experimental; Arthritis, Rheumatoid; Arthroscopy; Aspergillus; Aspergillus niger; Asteraceae; Asthma; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; Auditory Cortex; Autoantibodies; Autophagy; Bacteria; Bacterial Infections; Bacterial Proteins; Bacterial Typing Techniques; Base Composition; Base Sequence; Basketball; Beclin-1; Benzhydryl Compounds; Benzimidazoles; Benzo(a)pyrene; Benzofurans; Benzoxazines; Bereavement; beta Catenin; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Betacoronavirus; Betaine; Binding Sites; Biofilms; Biological Assay; Biological Availability; Biological Evolution; Biomarkers; Biomechanical Phenomena; Biopolymers; Biopsy; Bismuth; Blood Glucose; Blood Platelets; Blood Pressure; Body Composition; Body Weight; Bone Marrow; Bone Marrow Cells; Bone Regeneration; Boron; Botrytis; Brain Ischemia; Brain Neoplasms; Brain-Derived Neurotrophic Factor; Brazil; Breast Neoplasms; Breath Tests; Bronchoalveolar Lavage Fluid; Burkholderia; C-Reactive Protein; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Calcification, Physiologic; Calcium; Calcium Signaling; Calorimetry, Differential Scanning; Cameroon; Camptothecin; Candida; Candida albicans; Capillaries; Carbapenem-Resistant Enterobacteriaceae; Carbapenems; Carbohydrate Conformation; Carbon; Carbon Dioxide; Carbon Isotopes; Carcinoma, Ovarian Epithelial; Cardiac Output; Cardiomyopathy, Hypertrophic; Cardiotonic Agents; Cardiovascular Diseases; Caregivers; Carps; Case-Control Studies; Catalase; Catalysis; Cats; CD4 Lymphocyte Count; Cell Culture Techniques; Cell Differentiation; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Cellulose; Centrosome; Ceratopogonidae; Chickens; Child; China; Cholera Toxin; Choline; Cholinesterases; Chromatography, High Pressure Liquid; Chromatography, Liquid; Chromatography, Micellar Electrokinetic Capillary; Chromatography, Reverse-Phase; Chronic Disease; Cinnamates; Cities; Citrates; Climate Change; Clinical Trials, Phase III as Topic; Coal; Coal Mining; Cohort Studies; Coinfection; Colchicine; Colony Count, Microbial; Colorectal Neoplasms; Coloring Agents; Common Cold; Complement Factor H; Computational Biology; Computer Simulation; Continuous Positive Airway Pressure; Contrast Media; Coordination Complexes; Coronary Artery Bypass; Coronavirus 3C Proteases; Coronavirus Infections; Coronavirus Protease Inhibitors; Corynebacterium glutamicum; Cosmetics; COVID-19; Creatinine; Cross-Sectional Studies; Crotonates; Crystallography, X-Ray; Cues; Culicidae; Culture Media; Curcuma; Cyclopentanes; Cyclopropanes; Cymbopogon; Cystine; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C19 Inhibitors; Cytokines; Databases, Genetic; Death; Dendritic Cells; Density Functional Theory; Depsides; Diabetes Mellitus, Type 2; Diamond; Diarylheptanoids; Dibenzofurans; Dibenzofurans, Polychlorinated; Diclofenac; Diet; Dietary Carbohydrates; Dietary Supplements; Diffusion Magnetic Resonance Imaging; Dioxins; Diphenylamine; Disease Outbreaks; Disease Susceptibility; Disulfides; Dithiothreitol; Dizocilpine Maleate; DNA Methylation; DNA-Binding Proteins; DNA, Bacterial; Dogs; Dose-Response Relationship, Drug; Double-Blind Method; Doublecortin Protein; Drosophila melanogaster; Droughts; Drug Carriers; Drug Combinations; Drug Delivery Systems; Drug Liberation; Drug Resistance; Drug Resistance, Bacterial; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Dust; Dynactin Complex; Dysferlin; Echo-Planar Imaging; Echocardiography; Edaravone; Egypt; Elasticity; Electrodes; Electrolytes; Emodin; Emtricitabine; Endometriosis; Endothelium, Vascular; Endotoxins; Energy Metabolism; Energy Transfer; Enterobacteriaceae; Enterococcus faecalis; Enterotoxigenic Escherichia coli; Environmental Monitoring; Enzyme Inhibitors; Epidemiologic Factors; Epigenesis, Genetic; Erythrocytes; Escherichia coli; Escherichia coli Infections; Escherichia coli Vaccines; Esophageal Neoplasms; Esophagectomy; Esophagogastric Junction; Esterases; Esterification; Ethanol; Ethiopia; Ethnicity; Eucalyptus; Evidence-Based Practice; Exercise; Exercise Tolerance; Extracorporeal Membrane Oxygenation; Family; Fatty Acids; Feedback; Female; Ferric Compounds; Fibrin Fibrinogen Degradation Products; Filtration; Fish Diseases; Flavonoids; Flavonols; Fluorodeoxyglucose F18; Follow-Up Studies; Food Microbiology; Food Preservation; Forests; Fossils; Free Radical Scavengers; Freund's Adjuvant; Fruit; Fungi; Gallium; Gender Identity; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Genes, Bacterial; Genes, Plant; Genetic Predisposition to Disease; Genitalia; Genotype; Glomerulonephritis, IGA; Glottis; Glucocorticoids; Glucose; Glucuronides; Glutathione Transferase; Glycogen Synthase Kinase 3 beta; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Grassland; Guinea Pigs; Half-Life; Head Kidney; Heart Atria; Heart Rate; Heart Septum; HEK293 Cells; Hematopoietic Stem Cells; Hemodynamics; Hep G2 Cells; Hepacivirus; Hepatitis C; Hepatitis C, Chronic; Hepatocytes; Hesperidin; High-Frequency Ventilation; High-Temperature Requirement A Serine Peptidase 1; Hippocampus; Hirudins; History, 20th Century; History, 21st Century; HIV Infections; Homeostasis; Hominidae; Housing, Animal; Humans; Hydrocarbons, Brominated; Hydrogen Bonding; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxybutyrates; Hydroxyl Radical; Hypertension; Hypothyroidism; Image Interpretation, Computer-Assisted; Immunoconjugates; Immunogenic Cell Death; Indoles; Infant, Newborn; Infant, Premature; Infarction, Middle Cerebral Artery; Inflammation; Inflammation Mediators; Infrared Rays; Inhibitory Concentration 50; Injections, Intravenous; Interferon-gamma; Interleukin-23; Interleukin-4; Interleukin-6; Intermediate Filaments; Intermittent Claudication; Intestine, Small; Iridoid Glucosides; Iridoids; Iron; Isomerism; Isotope Labeling; Isoxazoles; Itraconazole; Kelch-Like ECH-Associated Protein 1; Ketoprofen; Kidney Failure, Chronic; Kinetics; Klebsiella pneumoniae; Lactams, Macrocyclic; Lactobacillus; Lactulose; Lakes; Lamivudine; Laparoscopy; Laparotomy; Laryngoscopy; Leucine; Limit of Detection; Linear Models; Lipid A; Lipopolysaccharides; Listeria monocytogenes; Liver; Liver Cirrhosis; Logistic Models; Longitudinal Studies; Losartan; Low Back Pain; Lung; Lupinus; Lupus Erythematosus, Systemic; Machine Learning; Macular Degeneration; Madin Darby Canine Kidney Cells; Magnetic Phenomena; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Magnetics; Malaria, Falciparum; Male; Mannans; MAP Kinase Signaling System; Mass Spectrometry; Melatonin; Membrane Glycoproteins; Membrane Proteins; Meniscectomy; Menisci, Tibial; Mephenytoin; Mesenchymal Stem Cells; Metal Nanoparticles; Metal-Organic Frameworks; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; Mice, Obese; Mice, Transgenic; Microbial Sensitivity Tests; Microcirculation; MicroRNAs; Microscopy, Video; Microtubules; Microvascular Density; Microwaves; Middle Aged; Minimally Invasive Surgical Procedures; Models, Animal; Models, Biological; Models, Molecular; Models, Theoretical; Molecular Docking Simulation; Molecular Structure; Molecular Weight; Morus; Mouth Floor; Multicenter Studies as Topic; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Muscle, Skeletal; Myocardial Ischemia; Myocardium; NAD; NADP; Nanocomposites; Nanoparticles; Naphthols; Nasal Lavage Fluid; Nasal Mucosa; Neisseria meningitidis; Neoadjuvant Therapy; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasms, Experimental; Neural Stem Cells; Neuroblastoma; Neurofilament Proteins; Neurogenesis; Neurons; New York; NF-E2-Related Factor 2; NF-kappa B; Nicotine; Nitriles; Nitrogen; Nitrogen Fixation; North America; Observer Variation; Occupational Exposure; Ochrobactrum; Oils, Volatile; Olea; Oligosaccharides; Omeprazole; Open Field Test; Optimism; Oregon; Oryzias; Osmolar Concentration; Osteoarthritis; Osteoblasts; Osteogenesis; Ovarian Neoplasms; Ovariectomy; Oxadiazoles; Oxidation-Reduction; Oxidative Stress; Oxygen; Ozone; p38 Mitogen-Activated Protein Kinases; Pakistan; Pandemics; Particle Size; Particulate Matter; Patient-Centered Care; Pelargonium; Peptides; Perception; Peripheral Arterial Disease; Peroxides; Pets; Pharmaceutical Preparations; Pharmacogenetics; Phenobarbital; Phenols; Phenotype; Phosphates; Phosphatidylethanolamines; Phosphines; Phospholipids; Phosphorus; Phosphorylation; Photoacoustic Techniques; Photochemotherapy; Photosensitizing Agents; Phylogeny; Phytoestrogens; Pilot Projects; Plant Components, Aerial; Plant Extracts; Plant Immunity; Plant Leaves; Plant Oils; Plants, Medicinal; Plasmodium berghei; Plasmodium falciparum; Platelet Activation; Platelet Function Tests; Pneumonia, Viral; Poaceae; Pogostemon; Poloxamer; Poly I; Poly(ADP-ribose) Polymerase Inhibitors; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Polycyclic Compounds; Polyethylene Glycols; Polylysine; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Population Dynamics; Portasystemic Shunt, Transjugular Intrahepatic; Positron Emission Tomography Computed Tomography; Postoperative Complications; Postprandial Period; Potassium Cyanide; Predictive Value of Tests; Prefrontal Cortex; Pregnancy; Prepulse Inhibition; Prevalence; Procalcitonin; Prodrugs; Prognosis; Progression-Free Survival; Proline; Proof of Concept Study; Prospective Studies; Protein Binding; Protein Conformation; Protein Domains; Protein Folding; Protein Multimerization; Protein Sorting Signals; Protein Structure, Secondary; Proton Pump Inhibitors; Protozoan Proteins; Psychometrics; Pulse Wave Analysis; Pyridines; Pyrrolidines; Quality of Life; Quantum Dots; Quinoxalines; Quorum Sensing; Radiopharmaceuticals; Rain; Random Allocation; Randomized Controlled Trials as Topic; Rats; Rats, Sprague-Dawley; Rats, Wistar; RAW 264.7 Cells; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptor, PAR-1; Receptors, CXCR4; Receptors, Estrogen; Receptors, Glucocorticoid; Receptors, Interleukin-1; Receptors, Interleukin-17; Receptors, Notch; Recombinant Fusion Proteins; Recombinant Proteins; Reducing Agents; Reflex, Startle; Regional Blood Flow; Regression Analysis; Reperfusion Injury; Reproducibility of Results; Republic of Korea; Respiratory Tract Diseases; Retrospective Studies; Reverse Transcriptase Inhibitors; Rhinitis, Allergic; Risk Assessment; Risk Factors; Rituximab; RNA, Messenger; RNA, Ribosomal, 16S; ROC Curve; Rosmarinic Acid; Running; Ruthenium; Rutin; Sarcolemma; Sarcoma; Sarcopenia; Sarcoplasmic Reticulum; SARS-CoV-2; Scavenger Receptors, Class A; Schools; Seasons; Seeds; Sequence Analysis, DNA; Severity of Illness Index; Sex Factors; Shock, Cardiogenic; Short Chain Dehydrogenase-Reductases; Signal Transduction; Silver; Singlet Oxygen; Sinusitis; Skin; Skin Absorption; Small Molecule Libraries; Smoke; Socioeconomic Factors; Soil; Soil Microbiology; Solid Phase Extraction; Solubility; Solvents; Spain; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared; Speech; Speech Perception; Spindle Poles; Spleen; Sporothrix; Staphylococcal Infections; Staphylococcus aureus; Stereoisomerism; Stomach Neoplasms; Stress, Physiological; Stroke Volume; Structure-Activity Relationship; Substrate Specificity; Sulfonamides; Surface Properties; Surface-Active Agents; Surveys and Questionnaires; Survival Rate; T-Lymphocytes, Cytotoxic; Tandem Mass Spectrometry; Temperature; Tenofovir; Terpenes; Tetracycline; Tetrapleura; Textiles; Thermodynamics; Thiobarbituric Acid Reactive Substances; Thrombin; Thyroid Hormones; Thyroid Neoplasms; Tibial Meniscus Injuries; Time Factors; Tissue Distribution; Titanium; Toluidines; Tomography, X-Ray Computed; Tooth; Tramadol; Transcription Factor AP-1; Transcription, Genetic; Transfection; Transgender Persons; Translations; Treatment Outcome; Triglycerides; Ubiquinone; Ubiquitin-Specific Proteases; United Kingdom; United States; Up-Regulation; Vascular Stiffness; Veins; Ventricular Remodeling; Viral Load; Virulence Factors; Virus Replication; Vitis; Voice; Voice Quality; Wastewater; Water; Water Pollutants, Chemical; Water-Electrolyte Balance; Weather; Wildfires; Wnt Signaling Pathway; Wound Healing; X-Ray Diffraction; Xenograft Model Antitumor Assays; Young Adult; Zoogloea | 2022 |
Effects of resistance training using elastic bands on muscle strength with or without a leucine supplement for 48 weeks in elderly patients with type 2 diabetes.
Topics: Aged; Cognition; Cognitive Dysfunction; Diabetes Mellitus, Type 2; Dietary Supplements; Female; Hand Strength; Humans; Leucine; Male; Muscle Strength; Organ Size; Resistance Training; Walking Speed | 2021 |
Intragastric administration of leucine and isoleucine does not reduce the glycaemic response to, or slow gastric emptying of, a carbohydrate-containing drink in type 2 diabetes.
Topics: Adult; Aged; Amino Acids, Branched-Chain; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 2; Dietary Supplements; Double-Blind Method; Energy Drinks; Gastric Emptying; Humans; Isoleucine; Leucine; Male; Middle Aged; Postprandial Period | 2021 |
Effect of an Enriched Protein Drink on Muscle Mass and Glycemic Control during Combined Lifestyle Intervention in Older Adults with Obesity and Type 2 Diabetes: A Double-Blind RCT.
Topics: Absorptiometry, Photon; Aged; Anthropometry; Body Composition; Diabetes Mellitus, Type 2; Dietary Proteins; Double-Blind Method; Exercise; Female; Glucose Tolerance Test; Glycemic Control; Humans; Insulin Resistance; Leucine; Life Style; Male; Middle Aged; Muscle Strength; Muscles; Obesity; Overweight; Proteins; Vitamin D; Weight Loss | 2020 |
Safety, Tolerability, and Biologic Activity of AXA1125 and AXA1957 in Subjects With Nonalcoholic Fatty Liver Disease.
Topics: Acetylcysteine; Administration, Oral; Arginine; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Combinations; Drug Tolerance; Female; Glutamine; Humans; Isoleucine; Leucine; Liver; Magnetic Resonance Imaging; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Single-Blind Method; Treatment Outcome; Valine | 2021 |
Effect of metformin on plasma metabolite profile in the Copenhagen Insulin and Metformin Therapy (CIMT) trial.
Topics: Aged; Carnitine; Chromatography, Liquid; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin Resistance; Isoleucine; Leucine; Lysophospholipids; Male; Mass Spectrometry; Metabolome; Metabolomics; Metformin; Middle Aged; Mitochondria; Tyrosine; Valine | 2018 |
Sodium nitrate co-ingestion with protein does not augment postprandial muscle protein synthesis rates in older, type 2 diabetes patients.
Topics: Aged; Blood Glucose; Carbon Isotopes; Diabetes Mellitus, Type 2; Dietary Proteins; Eating; Glycated Hemoglobin; Humans; Intestinal Absorption; Leucine; Male; Muscle Proteins; Muscle, Skeletal; Myofibrils; Nitrates; Phenylalanine; Postprandial Period; Protein Biosynthesis | 2016 |
Prolonged leucine supplementation does not augment muscle mass or affect glycemic control in elderly type 2 diabetic men.
Topics: Aged; Aging; Amino Acids; Blood Glucose; Body Composition; Diabetes Mellitus, Type 2; Dietary Supplements; Humans; Leucine; Lipids; Male; Muscle Strength; Muscle, Skeletal | 2011 |
Hydrolyzed casein decreases postprandial glucose concentrations in T2DM patients irrespective of leucine content.
Topics: Aged; Analysis of Variance; Blood Glucose; Caseins; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glucagon; Humans; Hypoglycemic Agents; Insulin; Leucine; Male; Middle Aged; Postprandial Period; Protein Hydrolysates | 2011 |
Amino acid ingestion strongly enhances insulin secretion in patients with long-term type 2 diabetes.
Topics: Amino Acids; Blood Glucose; Diabetes Mellitus, Type 2; Dietary Carbohydrates; Humans; Insulin; Insulin Secretion; Leucine; Male; Middle Aged; Phenylalanine; Protein Hydrolysates | 2003 |
Overproduction of VLDL1 driven by hyperglycemia is a dominant feature of diabetic dyslipidemia.
Topics: Adult; Apolipoproteins B; Blood Glucose; Cholesterol, HDL; Cholesterol, VLDL; Deuterium; Diabetes Mellitus, Type 2; Dyslipidemias; Glycerol; Humans; Hyperglycemia; Insulin Resistance; Leucine; Male; Triglycerides | 2005 |
Co-ingestion of a protein hydrolysate and amino acid mixture with carbohydrate improves plasma glucose disposal in patients with type 2 diabetes.
Topics: Blood Glucose; Case-Control Studies; Diabetes Mellitus, Type 2; Dietary Carbohydrates; Drug Interactions; Humans; Insulin; Insulin Secretion; Leucine; Male; Middle Aged; Phenylalanine; Protein Hydrolysates | 2005 |
Protein hydrolysate/leucine co-ingestion reduces the prevalence of hyperglycemia in type 2 diabetic patients.
Topics: Administration, Oral; Adult; Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 2; Humans; Hyperglycemia; Leucine; Prevalence; Protein Hydrolysates; Reference Values | 2006 |
A leucine repeat in the carnosinase gene CNDP1 is associated with diabetic end-stage renal disease in European Americans.
Topics: Adult; Aged; Alleles; Carnosine; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dipeptidases; Europe; Female; Genetic Linkage; Genetic Predisposition to Disease; Genotype; Humans; Kidney Failure, Chronic; Leucine; Male; Middle Aged; Polymorphism, Single Nucleotide; Risk Factors; Trinucleotide Repeats; United States; White People | 2007 |
Protein hydrolysate co-ingestion does not modulate 24 h glycemic control in long-standing type 2 diabetes patients.
Topics: Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 2; Dietary Supplements; Double-Blind Method; Drug Therapy, Combination; Homeostasis; Humans; Hypoglycemic Agents; Leucine; Middle Aged; Protein Hydrolysates | 2009 |
Differential effect of fenofibrate and atorvastatin on in vivo kinetics of apolipoproteins B-100 and B-48 in subjects with type 2 diabetes mellitus with marked hypertriglyceridemia.
Topics: Anticholesteremic Agents; Apolipoprotein B-100; Apolipoprotein B-48; Atorvastatin; Cholesterol; Diabetes Mellitus, Type 2; Double-Blind Method; Fenofibrate; Heptanoic Acids; Humans; Hypertriglyceridemia; Kinetics; Leucine; Male; Middle Aged; Pyrroles; Triglycerides | 2008 |
Epidural analgesia enhances the postoperative anabolic effect of amino acids in diabetes mellitus type 2 patients undergoing colon surgery.
Topics: Aged; Amino Acids; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Blood Glucose; Carbon Isotopes; Colon; Diabetes Mellitus, Type 2; Elective Surgical Procedures; Female; Humans; Keto Acids; Leucine; Male; Morphine; Postoperative Complications; Postoperative Period; Proteins | 2008 |
Effects of recombinant human insulin-like growth factor I and insulin on counterregulation during acute plasma glucose decrements in normal and type 2 (non-insulin-dependent) diabetic subjects.
Topics: Adult; Aged; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Epinephrine; Fatty Acids, Nonesterified; Female; Glucagon; Growth Hormone; Hormones; Humans; Hydrocortisone; Insulin; Insulin-Like Growth Factor I; Kinetics; Leucine; Male; Middle Aged; Norepinephrine; Recombinant Proteins | 1993 |
The stimulation of insulin secretion in non-insulin-dependent diabetic patients by amino acids and gliclazide in the basal and hyperglycemic state.
Topics: Aged; Arginine; Blood Glucose; C-Peptide; Cross-Over Studies; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Drug Synergism; Female; Gliclazide; Glucose Clamp Technique; Humans; Hyperglycemia; Hypoglycemic Agents; Infusions, Intravenous; Insulin; Insulin Secretion; Leucine; Male; Middle Aged; Time Factors | 1997 |
Increased fibrinogen production in type 2 diabetic patients without detectable vascular complications: correlation with plasma glucagon concentrations.
Topics: Adult; Blood Glucose; Capillaries; Diabetes Mellitus, Type 2; Fibrinogen; Glucagon; Humans; Insulin; Kinetics; Leucine; Lipids; Male; Middle Aged | 2000 |
106 other study(ies) available for leucine and Diabetes Mellitus, Adult-Onset
| Article | Year |
|---|---|
Association of Plasma Leucine-Rich Alpha-2 Glycoprotein 1 (LRG1) with All-Cause and Cause-Specific Mortality in Individuals with Type 2 Diabetes.
Topics: Cardiovascular Diseases; Cause of Death; Diabetes Mellitus, Type 2; Glycoproteins; Humans; Leucine | 2021 |
Modulation of transforming growth factor-β-induced kidney fibrosis by leucine-rich ⍺-2 glycoprotein-1.
Topics: Animals; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Endothelial Cells; Fibrosis; Glycoproteins; Humans; Kidney; Leucine; Mice; Smad3 Protein; Transforming Growth Factor beta; Transforming Growth Factor beta1; Transforming Growth Factors; Ureteral Obstruction | 2022 |
Determination of N-acetyl-DL-leucine in the saliva of healthy volunteers and diabetic patients using ultra-performance liquid chromatography with fluorescence detection.
Topics: Chromatography, High Pressure Liquid; Chromatography, Liquid; Diabetes Mellitus, Type 2; Healthy Volunteers; Humans; Leucine; Saliva; Stereoisomerism | 2022 |
Amino acid profile of skeletal muscle loss in type 2 diabetes: Results from a 7-year longitudinal study in asians.
Topics: Amino Acids; Amino Acids, Branched-Chain; Asian People; Diabetes Mellitus, Type 2; Humans; Isoleucine; Leucine; Longitudinal Studies; Muscle, Skeletal; Prospective Studies; Valine | 2022 |
The Association Between Leucine and Diabetic Retinopathy in Different Genders: A Cross-Sectional Study in Chinese Patients With Type 2 Diabetes.
Topics: China; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Humans; Leucine; Logistic Models; Male | 2022 |
Association between Higher Circulating Leucine-Rich α-2 Glycoprotein 1 Concentrations and Specific Plasma Ceramides in Postmenopausal Women with Type 2 Diabetes.
Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Ceramides; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Glycoproteins; Humans; Leucine; Middle Aged; Postmenopause | 2022 |
NMR-Based Metabolomic Analysis for the Effects of Trimethylamine N-Oxide Treatment on C2C12 Myoblasts under Oxidative Stress.
Topics: Alanine; Catalase; Diabetes Mellitus, Type 2; Glycine; Histidine; Humans; Hydrogen Peroxide; Isoleucine; Leucine; Magnetic Resonance Spectroscopy; Malondialdehyde; Methylamines; Myoblasts; Oxidative Stress; Phenylalanine; Phosphorylcholine; Superoxide Dismutase; Threonine; Valine | 2022 |
A glycogen storage disease type 1a patient with type 2 diabetes.
Topics: Adenoma; Adult; Diabetes Mellitus, Type 2; Electrolytes; Female; Glucose; Glucose-6-Phosphatase; Glycogen Storage Disease Type I; Humans; Insulins; Leucine; Proline; Starch | 2022 |
Urinary Metabolomics Study on the Protective Role of Cocoa in Zucker Diabetic Rats via
Topics: Amino Acids, Branched-Chain; Animals; Blood Glucose; Cacao; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Flavonoids; Glycated Hemoglobin; Isoleucine; Ketone Bodies; Leucine; Male; Metabolomics; Proton Magnetic Resonance Spectroscopy; Rats; Rats, Zucker; Valine | 2022 |
Liver autophagy-induced valine and leucine in plasma reflect the metabolic effect of sodium glucose co-transporter 2 inhibitor dapagliflozin.
Topics: Animals; Autophagy; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Glucose; Hypoglycemic Agents; Leucine; Liver; Mice; Sodium; Sodium-Glucose Transporter 2 Inhibitors; Symporters; Valine | 2022 |
Urine Leucine-Rich α-2 Glycoprotein 1 (LRG1) Predicts the Risk of Progression to End-Stage Kidney Disease in Patients With Type 2 Diabetes.
Topics: Diabetes Mellitus, Type 2; Disease Progression; Glomerular Filtration Rate; Glycoproteins; Humans; Kidney Failure, Chronic; Leucine; Transforming Growth Factor beta | 2023 |
Hepatic leucine carboxyl methyltransferase 1 (LCMT1) contributes to high fat diet-induced glucose intolerance through regulation of glycogen metabolism.
Topics: Animals; Diabetes Mellitus, Type 2; Diet, High-Fat; Glucose; Glucose Intolerance; Glycogen; Insulin Resistance; Leucine; Liver; Methyltransferases; Mice; Protein O-Methyltransferase | 2023 |
Protein and Leucine Intake at Main Meals in Elderly People with Type 2 Diabetes.
Topics: Aged; Breakfast; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Energy Intake; Feeding Behavior; Female; Humans; Leucine; Lunch; Male; Meals | 2023 |
Urinary metabolites associate with the presence of diabetic kidney disease in type 2 diabetes and mediate the effect of inflammation on kidney complication.
Topics: Biomarkers; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Inflammation; Interleukin-18; Kidney; Leucine | 2023 |
Leucine and Glutamic Acid as a Biomarker of Sarcopenic Risk in Japanese People with Type 2 Diabetes.
Topics: Biomarkers; Diabetes Mellitus, Type 2; Dietary Proteins; East Asian People; Glutamic Acid; Humans; Leucine; Muscle, Skeletal; Sarcopenia | 2023 |
Sex-Specific Correlation Analysis of Branched-Chain Amino Acids in Dietary Intakes and Plasma among Chinese Adults.
Topics: Amino Acids, Branched-Chain; Case-Control Studies; China; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diet; East Asian People; Female; Humans; Isoleucine; Leucine; Male; Middle Aged; Prospective Studies; Valine | 2023 |
Sodium-glucose cotransporter 2 inhibitor canagliflozin alleviates vascular calcification through suppression of nucleotide-binding domain, leucine-rich-containing family, pyrin domain-containing-3 inflammasome.
Topics: Animals; Canagliflozin; Diabetes Mellitus, Type 2; Glucose; Humans; Inflammasomes; Leucine; Mice; Myocytes, Smooth Muscle; NLR Family, Pyrin Domain-Containing 3 Protein; Nucleotides; Osteogenesis; Pyrin Domain; Rats; Renal Insufficiency, Chronic; Sodium; Vascular Calcification; X-Ray Microtomography | 2023 |
Metformin activates AMPK and mTOR to Inhibit RANKL-stimulated osteoclast formation.
Topics: AMP-Activated Protein Kinases; Animals; Diabetes Mellitus, Type 2; Leucine; Metformin; Mice; Osteoclasts; TOR Serine-Threonine Kinases | 2023 |
Relationship between plasma leucine-rich α-2-glycoprotein 1 and urinary albumin excretion in patients with type 2 diabetes.
Topics: Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Glycoproteins; Humans; Leucine | 2023 |
The association between dietary amino acid profile and the risk of type 2 diabetes: Ravansar non-communicable disease cohort study.
Topics: Adult; Amino Acids; Case-Control Studies; Cohort Studies; Diabetes Mellitus, Type 2; Diet; Female; Humans; Leucine; Male; Noncommunicable Diseases | 2023 |
Characteristics of amino acid profiles and incretin hormones in patients with gallstone disease: a pilot study.
Topics: Adult; Aged; Cholecystolithiasis; Diabetes Mellitus, Type 2; Female; Humans; Incretins; Isoleucine; Leucine; Lysine; Male; Metabolic Diseases; Middle Aged; Pilot Projects; Valine | 2019 |
Elevated Plasma Branched-Chain Amino Acid Levels Correlate With Type 2 Diabetes-Related Metabolic Disturbances.
Topics: Adult; Aged; Amino Acids, Branched-Chain; Case-Control Studies; Diabetes Complications; Diabetes Mellitus, Type 2; Female; Humans; Insulin Resistance; Leucine; Male; Metabolic Diseases; Middle Aged; Mitochondria; Oxidation-Reduction | 2021 |
The Association Between Leucine and Diabetic Nephropathy in Different Gender: A Cross-Sectional Study in Chinese Patients With Type 2 Diabetes.
Topics: Adult; Aged; Biomarkers; China; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Leucine; Male; Middle Aged; Risk Factors; Sex Characteristics | 2020 |
Triangulating evidence from longitudinal and Mendelian randomization studies of metabolomic biomarkers for type 2 diabetes.
Topics: Adult; Aged; Betaine; Biomarkers; Carnitine; Case-Control Studies; Diabetes Mellitus, Type 2; Early Diagnosis; Female; Genetic Predisposition to Disease; Glutamic Acid; Humans; Leucine; Lysine; Male; Mannose; Mendelian Randomization Analysis; Metabolome; Middle Aged; Valine | 2021 |
Comparative Effects of the Branched-Chain Amino Acids, Leucine, Isoleucine and Valine, on Gastric Emptying, Plasma Glucose, C-Peptide and Glucagon in Healthy Men.
Topics: Adult; Amino Acids, Branched-Chain; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Double-Blind Method; Gastric Emptying; Gastric Inhibitory Polypeptide; Glucagon; Humans; Insulin; Isoleucine; Leucine; Male; Middle Aged; Postprandial Period; Valine; Whey Proteins; Young Adult | 2021 |
Effects of
Topics: Aged; Amino Acids, Branched-Chain; Cardiovascular Diseases; China; Cholesterol, HDL; Diabetes Mellitus, Type 2; Female; Genotype; Humans; Incidence; Isoleucine; Leucine; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Polymorphism, Single Nucleotide; Protein Phosphatase 2C; Valine | 2021 |
Hypoglycemic and Hypolipidemic Effects of Leucine, Zinc, and Chromium, Alone and in Combination, in Rats with Type 2 Diabetes.
Topics: Animals; Blood Glucose; Chromium; Combined Modality Therapy; Diabetes Mellitus, Type 2; Dietary Supplements; Glyburide; Hyperglycemia; Hyperlipidemias; Hypoglycemic Agents; Hypolipidemic Agents; Insulin; Insulin Resistance; Leucine; Lipids; Male; Random Allocation; Rats, Wistar; Streptozocin; Zinc | 2017 |
Serum metabolomics differentiating pancreatic cancer from new-onset diabetes.
Topics: Adenocarcinoma; Adult; Age Factors; Aged; Biomarkers, Tumor; Body Mass Index; CA-19-9 Antigen; Carcinoma, Pancreatic Ductal; Chromatography, Liquid; Diabetes Mellitus, Type 2; Diagnosis, Differential; Early Detection of Cancer; Feasibility Studies; Female; Humans; Isoleucine; Leucine; Lipid Metabolism; Male; Mass Spectrometry; Metabolic Networks and Pathways; Metabolome; Metabolomics; Middle Aged; Neoplasm Staging; Pancreatic Neoplasms; Principal Component Analysis; Sensitivity and Specificity; Serologic Tests; Valine | 2017 |
Application of Raman spectroscopy in type 2 diabetes screening in blood using leucine and isoleucine amino-acids as biomarkers and in comparative anti-diabetic drugs efficacy studies.
Topics: Animals; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Hypoglycemic Agents; Isoleucine; Leucine; Momordica; Plant Extracts; Rats; Rats, Sprague-Dawley; Spectrum Analysis, Raman | 2017 |
Serum metabolomic profile of incident diabetes.
Topics: Amino Acids, Branched-Chain; Asparagine; Atherosclerosis; Blood Glucose; Diabetes Mellitus, Type 2; Erythritol; Female; Glucose; Humans; Isoleucine; Lactic Acid; Leucine; Male; Maryland; Metabolome; Middle Aged; Minnesota; Mississippi; North Carolina; Prospective Studies; Risk Factors; Trehalose; Valine | 2018 |
The characterisation of hepatic mitochondrial function in patients with non-alcoholic fatty liver disease (NAFLD) using the
Topics: Adult; Breath Tests; Carbon Isotopes; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Humans; Keto Acids; Leucine; Linear Models; Male; Middle Aged; Mitochondria, Liver; Multivariate Analysis; Non-alcoholic Fatty Liver Disease | 2018 |
Associations of increased physical performance and change in body composition with molecular pathways of heart disease and diabetes risk.
Topics: Adipose Tissue; Adolescent; Adult; Body Composition; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Cohort Studies; Diabetes Mellitus, Type 2; Electric Impedance; Finland; Heart Diseases; Humans; Inflammation; Leucine; Male; Military Personnel; Muscle, Skeletal; Physical Functional Performance; Prospective Studies; Risk; Young Adult | 2019 |
Evaluation of a rare glucose-dependent insulinotropic polypeptide receptor variant in a patient with diabetes.
Topics: Adolescent; Age of Onset; Amino Acid Substitution; Animals; Arginine; Child; Chlorocebus aethiops; Cohort Studies; COS Cells; Diabetes Mellitus, Type 2; Female; Gene Frequency; Genome-Wide Association Study; Germany; Homozygote; Humans; Insulin Resistance; Leucine; Male; Pediatric Obesity; Polymorphism, Single Nucleotide; Receptors, Gastrointestinal Hormone | 2019 |
Nine Amino Acids Are Associated With Decreased Insulin Secretion and Elevated Glucose Levels in a 7.4-Year Follow-up Study of 5,181 Finnish Men.
Topics: Aged; Alanine; Amino Acids; Aspartic Acid; Blood Glucose; Diabetes Mellitus, Type 2; Finland; Follow-Up Studies; Glutamic Acid; Humans; Insulin Resistance; Insulin Secretion; Isoleucine; Leucine; Male; Metabolomics; Middle Aged; Phenylalanine; Risk Factors; Tryptophan; Tyrosine; Valine | 2019 |
De Novo Mutation of m.3243A>G together with m.16093T>C Associated with Atypical Clinical Features in a Pedigree with MIDD Syndrome.
Topics: Adenosine Triphosphate; Adult; Aged; Aged, 80 and over; Deafness; Diabetes Mellitus, Type 2; DNA, Mitochondrial; Family Health; Female; Genetic Predisposition to Disease; Humans; Leucine; Leukocytes, Mononuclear; Magnetic Resonance Imaging; Male; Middle Aged; Mitochondrial Diseases; Mutation; Pedigree; Phenotype; Point Mutation; Reactive Oxygen Species; RNA, Transfer; Sequence Analysis, DNA | 2019 |
Amino acids and wound healing in people with limb-threatening diabetic foot ulcers.
Topics: Aged; Aged, 80 and over; Amino Acids; Amputation, Surgical; Arginine; Coronary Artery Disease; Diabetes Mellitus, Type 2; Diabetic Foot; Female; Hospitalization; Humans; Isoleucine; Leucine; Male; Threonine; Treatment Outcome; Wound Healing | 2019 |
Hyperleucinemia causes hippocampal retromer deficiency linking diabetes to Alzheimer's disease.
Topics: Alzheimer Disease; Analysis of Variance; Animals; Cell Line, Tumor; Diabetes Mellitus, Type 2; Disease Progression; Enzyme-Linked Immunosorbent Assay; Glucose Tolerance Test; Hippocampus; Humans; Leptin; Leucine; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuroblastoma; Vesicular Transport Proteins | 2014 |
Sex specific association between carnosinase gene CNDP1 and cardiovascular mortality in patients with type 2 diabetes (ZODIAC-22).
Topics: Aged; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dipeptidases; Disease Progression; Female; Follow-Up Studies; Glomerular Filtration Rate; Homozygote; Humans; Leucine; Male; Middle Aged; Polymorphism, Genetic; Proportional Hazards Models; Prospective Studies; Sex Factors | 2015 |
Effect of 10% dietary protein intake on whole body protein kinetics in type 2 diabetic adults.
Topics: Amino Acids; Blood Glucose; Body Mass Index; Body Weight; Diabetes Mellitus, Type 2; Diet, Protein-Restricted; Dietary Proteins; Energy Intake; Female; Glucose Clamp Technique; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Leucine; Male; Mental Recall; Middle Aged; Obesity; Sex Factors; Waist Circumference | 2015 |
The Effects of Leucine, Zinc, and Chromium Supplements on Inflammatory Events of the Respiratory System in Type 2 Diabetic Rats.
Topics: Animals; Antioxidants; Bronchoalveolar Lavage Fluid; Chromium; Diabetes Mellitus, Type 2; Dietary Supplements; Disease Models, Animal; Insulin; Leucine; Lung; Male; Oxidative Stress; Pneumonia; Rats, Wistar; Trachea; Zinc | 2015 |
Decreased VLDL-Apo B 100 Fractional Synthesis Rate Despite Hypertriglyceridemia in Subjects With Type 2 Diabetes and Nephropathy.
Topics: Adult; Aged; Apolipoprotein B-100; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Hypertriglyceridemia; Insulin; Kinetics; Leucine; Lipoproteins, VLDL; Male; Middle Aged; Radionuclide Imaging; Radiopharmaceuticals | 2015 |
Branched-chain and aromatic amino acid profiles and diabetes risk in Chinese populations.
Topics: Adult; Aged; Amino Acids, Aromatic; Amino Acids, Branched-Chain; China; Chromatography, Liquid; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Isoleucine; Leucine; Longitudinal Studies; Male; Mass Spectrometry; Middle Aged; Phenylalanine; Risk Factors; Tyrosine; Valine; Young Adult | 2016 |
Lactation is associated with altered metabolomic signatures in women with gestational diabetes.
Topics: Adult; Amino Acids, Branched-Chain; Diabetes Mellitus, Type 2; Diabetes, Gestational; Female; Humans; Lactation; Leucine; Metabolomics; Postpartum Period; Pregnancy | 2016 |
Tryptophan Predicts the Risk for Future Type 2 Diabetes.
Topics: Adult; Aged; Biomarkers; Blood Glucose; Case-Control Studies; China; Diabetes Mellitus, Type 2; Fasting; Female; Humans; Insulin; Insulin Resistance; Isoleucine; Leucine; Longitudinal Studies; Male; Middle Aged; Phenylalanine; Predictive Value of Tests; Prognosis; Risk Factors; Tryptophan; Tyrosine; Valine | 2016 |
Genetic polymorphisms in extracellular superoxide dismutase Leu53Leu, Arg213Gly, and Ala40Thr and susceptibility to type 2 diabetes mellitus.
Topics: Adult; Alanine; Arginine; Asian People; Diabetes Mellitus, Type 2; Female; Genetic Predisposition to Disease; Genotype; Glutamine; Humans; Leucine; Male; Middle Aged; Polymorphism, Single Nucleotide; Regression Analysis; Superoxide Dismutase; Threonine | 2016 |
Anabolic resistance does not explain sarcopenia in patients with type 2 diabetes mellitus, compared with healthy controls, despite reduced mTOR pathway activity.
Topics: Absorptiometry, Photon; Adaptor Proteins, Signal Transducing; Aged; Amino Acids, Essential; Anabolic Agents; Blood Glucose; Body Composition; Body Mass Index; Case-Control Studies; Cell Cycle Proteins; Diabetes Mellitus, Type 2; Humans; Insulin; Keto Acids; Leucine; Male; Middle Aged; Muscle Proteins; Muscle, Skeletal; Obesity; Phosphoproteins; Phosphorylation; Postprandial Period; Protein Biosynthesis; Ribosomal Protein S6 Kinases, 70-kDa; Risk Factors; Sarcopenia; Signal Transduction; TOR Serine-Threonine Kinases | 2017 |
The metabolites in peripheral blood mononuclear cells showed greater differences between patients with impaired fasting glucose or type 2 diabetes and healthy controls than those in plasma.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Adult; Aged; Biomarkers; Blood Glucose; Case-Control Studies; Diabetes Mellitus, Type 2; Fasting; Female; Glucose Metabolism Disorders; Humans; Inflammation Mediators; Leucine; Leukocytes, Mononuclear; Lysophosphatidylcholines; Male; Metabolomics; Middle Aged; Proline; Valine | 2017 |
The L162V polymorphism of the peroxisome proliferator activated receptor alpha gene (PPARA) is not associated with type 2 diabetes, BMI or body fat composition.
Topics: Adult; Body Fat Distribution; Body Mass Index; Diabetes Mellitus, Type 2; Female; Humans; Leucine; Male; Middle Aged; Polymorphism, Single Nucleotide; PPAR alpha; Risk Factors | 2009 |
The Leu72Met polymorphism of the ghrelin gene is associated with a decreased risk for type 2 diabetes.
Topics: Aged; Atherosclerosis; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Genetic Predisposition to Disease; Genotype; Ghrelin; Humans; Leucine; Male; Methionine; Middle Aged; Polymorphism, Genetic; Reference Values; White People | 2009 |
A Leu184Val polymorphism in PCK1 gene is associated with type 2 diabetes in Eastern Chinese population with BMI<23 kg/m2.
Topics: Aged; Amino Acid Substitution; Animals; Body Mass Index; Case-Control Studies; China; CHO Cells; Cricetinae; Cricetulus; Diabetes Mellitus, Type 2; Female; Genetic Linkage; Humans; Intracellular Signaling Peptides and Proteins; Leucine; Male; Middle Aged; Phosphoenolpyruvate Carboxykinase (GTP); Polymorphism, Single Nucleotide; Transfection; Valine | 2009 |
The Leu262Val polymorphism of presenilin associated rhomboid like protein (PARL) is associated with earlier onset of type 2 diabetes and increased urinary microalbumin creatinine ratio in an Irish case-control population.
Topics: Age of Onset; Albuminuria; Amino Acid Substitution; Animals; Case-Control Studies; Creatinine; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Disease Models, Animal; Genetic Variation; Gerbillinae; Humans; Hyperinsulinism; Ireland; Leucine; Metalloproteases; Mitochondrial Proteins; Polymorphism, Single Nucleotide; Reference Values; Valine | 2009 |
Mitochondrial dysfunction contributes to impaired insulin secretion in INS-1 cells with dominant-negative mutations of HNF-1alpha and in HNF-1alpha-deficient islets.
Topics: Adenosine Triphosphate; Animals; Base Sequence; Cell Line; Diabetes Mellitus, Type 2; DNA Primers; Female; Glucose; Glucose Transporter Type 2; Glutamine; Glycolysis; Hepatocyte Nuclear Factor 1-alpha; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Mice; Mice, Knockout; Mitochondria; Mutation; Oxidative Phosphorylation; Pyruvic Acid; Rats; RNA, Messenger | 2009 |
Metabonomics research of diabetic nephropathy and type 2 diabetes mellitus based on UPLC-oaTOF-MS system.
Topics: Adult; Aged; Biomarkers; Chromatography, High Pressure Liquid; Cluster Analysis; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Leucine; Male; Metabolome; Metabolomics; Middle Aged; Principal Component Analysis; Spectrometry, Mass, Electrospray Ionization; Sphingosine | 2009 |
Augmentation of insulin secretion by leucine supplementation in malnourished rats: possible involvement of the phosphatidylinositol 3-phosphate kinase/mammalian target protein of rapamycin pathway.
Topics: Animals; Blood Proteins; Body Weight; Diabetes Mellitus, Type 2; Dietary Supplements; Glucose Tolerance Test; Insulin; Insulin Secretion; Insulin-Secreting Cells; Intracellular Signaling Peptides and Proteins; Leucine; Male; Malnutrition; Phosphatidylinositol Phosphates; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Protein S6 Kinases; RNA; TOR Serine-Threonine Kinases | 2010 |
Association between CNDP1 genotype and diabetic nephropathy is sex specific.
Topics: Age of Onset; Aged; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dipeptidases; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homozygote; Humans; Leucine; Male; Middle Aged; Reference Values; Repetitive Sequences, Amino Acid; Sex Characteristics; White People | 2010 |
The role of aromatic side-chains in amyloid growth and membrane interaction of the islet amyloid polypeptide fragment LANFLVH.
Topics: Alanine; Amino Acid Sequence; Amino Acids, Aromatic; Calorimetry, Differential Scanning; Cell Membrane; Diabetes Mellitus, Type 2; Humans; Hydrophobic and Hydrophilic Interactions; Islet Amyloid Polypeptide; Leucine; Lipid Bilayers; Microscopy, Atomic Force; Molecular Dynamics Simulation; Molecular Sequence Data; Peptide Fragments; Phenylalanine; Temperature | 2011 |
A time-resolved fluorescence probe for dipeptidyl peptidase 4 and its application in inhibitor screening.
Topics: Diabetes Mellitus, Type 2; Dipeptides; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Leucine; Metalloproteins; Molecular Structure; Spectrometry, Fluorescence; Terbium; Thermodynamics; Time Factors | 2010 |
Investigations of a compartmental model for leucine kinetics using non-linear mixed effects models with ordinary and stochastic differential equations.
Topics: Case-Control Studies; Diabetes Mellitus, Type 2; Humans; Kinetics; Leucine; Likelihood Functions; Mathematical Concepts; Models, Biological; Nonlinear Dynamics; Stochastic Processes | 2012 |
Association of ghrelin Leu72Met polymorphism with type 2 diabetes mellitus in Chinese population.
Topics: Base Sequence; Case-Control Studies; China; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; DNA Primers; Ghrelin; Humans; Leucine; Methionine; Polymerase Chain Reaction; Polymorphism, Genetic | 2012 |
Circulating branched-chain amino acid concentrations are associated with obesity and future insulin resistance in children and adolescents.
Topics: Adolescent; Amino Acids, Branched-Chain; Biomarkers; Blood Glucose; Body Mass Index; Child; Child Nutrition Disorders; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Fasting; Female; Humans; Insulin; Insulin Resistance; Insulin Secretion; Isoleucine; Leucine; Longitudinal Studies; Male; Massachusetts; Obesity; Predictive Value of Tests; Valine | 2013 |
Role of aromatic interactions in amyloid formation by islet amyloid polypeptide.
Topics: Amino Acid Sequence; Amino Acid Substitution; Diabetes Mellitus, Type 2; Humans; Islet Amyloid Polypeptide; Kinetics; Leucine; Models, Molecular; Molecular Sequence Data; Phenylalanine; Propanols; Tyrosine | 2013 |
Synthesis rate of muscle proteins, muscle functions, and amino acid kinetics in type 2 diabetes.
Topics: Amino Acids; Blood Glucose; Carbon Isotopes; Diabetes Mellitus, Type 2; Energy Intake; Humans; Hypoglycemic Agents; Insulin; Kinetics; Leucine; Middle Aged; Muscle Fatigue; Muscle Proteins; Muscle, Skeletal; Phenylalanine; Reference Values | 2002 |
Insulin effect on leucine kinetics in type 2 diabetes mellitus.
Topics: Blood Glucose; Body Mass Index; C-Peptide; Caproates; Carbon Isotopes; Diabetes Mellitus, Type 2; Female; Glucose; Glucose Clamp Technique; Humans; Insulin; Kinetics; Leucine; Male; Middle Aged; Proteins | 2002 |
Polymorphisms of the insulin receptor substrate-2 in patients with type 2 diabetes.
Topics: Adult; Aged; Alleles; Aspartic Acid; Cohort Studies; Diabetes Mellitus, Type 2; Fibroblasts; Gene Frequency; Glycine; Heterozygote; Humans; Insulin Receptor Substrate Proteins; Intracellular Signaling Peptides and Proteins; Leucine; Middle Aged; Phosphoproteins; Polymorphism, Genetic; Valine | 2003 |
Identification and functional characterization of a novel mutation of hepatocyte nuclear factor-1alpha gene in a Korean family with MODY3.
Topics: Amino Acid Substitution; Arginine; Binding Sites; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Female; Glucose Transporter Type 2; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Humans; Insulin; Korea; Leucine; Male; Models, Molecular; Monosaccharide Transport Proteins; Mutation, Missense; Nuclear Proteins; Pedigree; Promoter Regions, Genetic; Protein Conformation; Transcription Factors | 2003 |
Missense mutation of Pro387Leu in protein tyrosine phosphatase-1B (PTP-1B) is not associated with type 2 diabetes in a Chinese Han population.
Topics: Asian People; Diabetes Mellitus, Type 2; Genetic Predisposition to Disease; Humans; Leucine; Mutation, Missense; Proline; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases | 2003 |
A new mutation in the hepatocyte nuclear factor-1-alpha gene (P224S) in a newly discovered German family with maturity-onset diabetes of the young 3 (MODY 3). Family members carry additionally the homozygous I27L amino acid polymorphism in the HNF1 alpha
Topics: Adolescent; Aged; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Exons; Female; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Homozygote; Humans; Insulin Resistance; Isoleucine; Leucine; Male; Mutation; Nuclear Proteins; Proline; Serine; Transcription Factors | 2004 |
Expression, purification, and C-terminal amidation of recombinant human glucagon-like peptide-1.
Topics: Animals; Arginine; Cathepsin A; Chromatography, Affinity; Chromatography, Ion Exchange; Cyanogen Bromide; Diabetes Mellitus, Type 2; Escherichia coli; Female; Gene Expression; Glucagon; Glucagon-Like Peptide 1; Glucose; Glutathione Transferase; Humans; Insulin; Leucine; Peptide Fragments; Protein Precursors; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins | 2004 |
Postabsorptive and insulin-stimulated energy homeostasis and leucine turnover in offspring of type 2 diabetic patients.
Topics: Adult; Case-Control Studies; Diabetes Mellitus, Type 2; Energy Metabolism; Female; Glucose; Homeostasis; Humans; Hypoglycemic Agents; Insulin; Leucine; Male; Postprandial Period | 2004 |
Type 2 diabetes mellitus and the catabolic response to surgery.
Topics: Adult; Aged; Analysis of Variance; Blood Glucose; Colorectal Surgery; Diabetes Mellitus, Type 2; Female; Glucose; Humans; Leucine; Male; Middle Aged; Oxidation-Reduction; Proteins | 2005 |
Leu7Pro polymorphism in the neuropeptide Y (NPY) gene is associated with impaired glucose tolerance and type 2 diabetes in Swedish men.
Topics: Adult; Alleles; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 2; Fasting; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glucose Intolerance; Heterozygote; Humans; Insulin; Leucine; Male; Middle Aged; Neuropeptide Y; Odds Ratio; Polymerase Chain Reaction; Polymorphism, Genetic; Proline; Sex Characteristics; Sweden | 2005 |
Molecular scanning of the betacellulin gene for mutations in type 2 diabetic patients.
Topics: Aged; Amino Acid Substitution; Base Sequence; Betacellulin; Cysteine; Cytosine; Diabetes Mellitus, Type 2; Female; Genetic Testing; Genetic Variation; Glycine; Humans; Intercellular Signaling Peptides and Proteins; Leucine; Male; Methionine; Middle Aged; Molecular Sequence Data; Mutation; Mutation, Missense; Polymorphism, Single Nucleotide; Thymine; Transcription Initiation Site | 2005 |
Carnosine as a protective factor in diabetic nephropathy: association with a leucine repeat of the carnosinase gene CNDP1.
Topics: Aged; Carnosine; Cells, Cultured; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dipeptidases; Female; Gene Expression; Genetic Predisposition to Disease; Glucose; Humans; Kidney; Leucine; Male; Middle Aged; Repetitive Sequences, Amino Acid; RNA, Messenger; Sequence Alignment | 2005 |
Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cells, Cultured; Diabetes Mellitus, Type 2; Glucose; Humans; Insulin; Insulin Receptor Substrate Proteins; Leucine; Mice; Monomeric GTP-Binding Proteins; Mutation; Neuropeptides; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Kinases; Proteins; Proto-Oncogene Proteins c-akt; Ras Homolog Enriched in Brain Protein; Rats; Regulatory-Associated Protein of mTOR; Serine; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases | 2006 |
Leucine regulation of glucokinase and ATP synthase sensitizes glucose-induced insulin secretion in pancreatic beta-cells.
Topics: Animals; Calcium; Cells, Cultured; Diabetes Mellitus, Type 2; Gene Expression Regulation, Enzymologic; Glucokinase; Glucose; Humans; Insulin; Insulin Secretion; Insulin-Secreting Cells; Leucine; Male; Mitochondrial Proton-Translocating ATPases; NADP; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2006 |
Albumin and fibrinogen synthesis and insulin effect in type 2 diabetic patients with normoalbuminuria.
Topics: Adult; Case-Control Studies; Diabetes Mellitus, Type 2; Fibrinogen; Glucagon; Humans; Hypertension; Hypoglycemic Agents; Insulin; Leucine; Male; Serum Albumin | 2006 |
Co-ingestion of a protein hydrolysate with or without additional leucine effectively reduces postprandial blood glucose excursions in Type 2 diabetic men.
Topics: Administration, Oral; Amino Acids; Beverages; Blood Glucose; Body Mass Index; Body Size; Diabetes Mellitus, Type 2; Diet, Diabetic; Humans; Leucine; Male; Middle Aged; Postprandial Period; Protein Hydrolysates; Reference Values | 2006 |
Leu7Pro polymorphism of PreproNPY associated with an increased risk for type II diabetes in middle-aged subjects.
Topics: Adult; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 2; Female; Gene Frequency; Genotype; Ghrelin; Humans; Hypertension; Insulin; Insulin Secretion; Leucine; Male; Middle Aged; Neuropeptide Y; Peptide Hormones; Polymorphism, Genetic; Proline; Protein Precursors; Risk Factors | 2007 |
Impact of the Leu7Pro polymorphism of preproNPY on diurnal NPY and hormone secretion in type 2 diabetes.
Topics: Aged; Amino Acid Substitution; Blood Glucose; Blood Pressure; Circadian Rhythm; Diabetes Mellitus, Type 2; Female; Humans; Hydrocortisone; Leptin; Leucine; Male; Middle Aged; Neuropeptide Y; Polymorphism, Genetic; Proline; Protein Precursors | 2007 |
Insulin resistance of protein metabolism in type 2 diabetes.
Topics: Adult; Amino Acids; Blood Chemical Analysis; Body Mass Index; Diabetes Mellitus, Type 2; Female; Follicular Phase; Glucose Clamp Technique; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Leucine; Male; Middle Aged; Proteins; Reference Values | 2008 |
Effects of dietary protein restriction on albumin and fibrinogen synthesis in macroalbuminuric type 2 diabetic patients.
Topics: Adult; Albumins; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diet, Protein-Restricted; Dietary Proteins; Female; Fibrinogen; Humans; Leucine; Male; Middle Aged; Proteinuria; Treatment Outcome | 2008 |
A subtype of diabetes mellitus associated with a mutation of mitochondrial DNA.
Topics: Adolescent; Adult; Aged; Base Sequence; Child; Child, Preschool; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; DNA, Mitochondrial; Female; Humans; Insulin Resistance; Leucine; Male; Middle Aged; Molecular Sequence Data; Mutation; Pedigree | 1994 |
Different sensitivity of glucose and amino acid metabolism to insulin in NIDDM.
Topics: Aged; Amino Acids; Analysis of Variance; Blood Glucose; Calorimetry; Carbon Radioisotopes; Diabetes Mellitus, Type 2; Female; Glucose; Glucose Clamp Technique; Humans; Infusions, Intravenous; Insulin; Leucine; Male; Middle Aged; Reference Values; Time Factors | 1993 |
Paraoxonase polymorphism Met-Leu54 is associated with modified serum concentrations of the enzyme. A possible link between the paraoxonase gene and increased risk of cardiovascular disease in diabetes.
Topics: Aged; Alleles; Arginine; Aryldialkylphosphatase; Cardiovascular Diseases; Cholesterol; Diabetes Mellitus, Type 2; DNA; Esterases; Female; Gene Expression Regulation; Genetic Linkage; Humans; Leucine; Lipoproteins, HDL; Male; Middle Aged; Odds Ratio; Point Mutation; Polymorphism, Genetic; Risk Factors | 1997 |
Defective regulation of triglyceride metabolism by insulin in the liver in NIDDM.
Topics: Apolipoproteins B; Cholesterol; Cholesterol, HDL; Deuterium; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Glucose Clamp Technique; Humans; Hyperglycemia; Hyperinsulinism; Infusions, Intravenous; Insulin; Leucine; Lipoproteins, VLDL; Liver; Male; Middle Aged; Models, Biological; Radioisotope Dilution Technique; Reference Values; Triglycerides | 1997 |
High density lipoprotein apolipoprotein AI kinetics in NIDDM: a stable isotope study.
Topics: Adult; Apolipoprotein A-I; Blood Glucose; Cholesterol; Cholesterol, HDL; Deuterium; Diabetes Mellitus, Type 2; Female; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Kinetics; Leucine; Lipoproteins, HDL; Male; Middle Aged; Radioisotope Dilution Technique; Reference Values; Triglycerides | 1997 |
Turnover of pro- and mature apolipoprotein A-I in diabetic patients and normolipidaemic controls.
Topics: Apolipoprotein A-I; Carbon Isotopes; Diabetes Mellitus, Type 2; Humans; Leucine; Lipoprotein(a); Lipoproteins, HDL; Reference Values | 1997 |
Glucose metabolism in Goto-Kakizaki rat islets.
Topics: Acetates; Adenosine Triphosphate; Animals; Carbon Dioxide; Diabetes Mellitus, Type 2; Glucose; In Vitro Techniques; Insulin; Islets of Langerhans; Lactic Acid; Leucine; Male; Oxidation-Reduction; Rats; Rats, Mutant Strains | 1998 |
The effect of two frequent amino acid variants of the hepatocyte nuclear factor-1alpha gene on estimates of the pancreatic beta-cell function in Caucasian glucose-tolerant first-degree relatives of type 2 diabetic patients.
Topics: Adult; Amino Acid Substitution; Asparagine; C-Peptide; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Female; Genetic Variation; Glucose Tolerance Test; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Humans; Insulin; Islets of Langerhans; Isoleucine; Leucine; Male; Middle Aged; Nuclear Proteins; Serine; Transcription Factors; White People | 1998 |
Decreased pancreatic islet response to L-leucine in the spontaneously diabetic GK rat: enzymatic, metabolic and secretory data.
Topics: Animals; Biological Transport; Blood Glucose; Diabetes Mellitus, Type 2; DNA; Glucose; Glutamate Dehydrogenase; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Leucine Transaminase; Male; Rats; Rats, Mutant Strains; Rats, Wistar; Reference Values; Transaminases | 1999 |
Significant improvement of apolipoprotein B-containing lipoprotein metabolism by insulin treatment in patients with non-insulin-dependent diabetes mellitus.
Topics: Apolipoproteins B; Blood Glucose; Carbon Isotopes; Cholesterol; Cholesterol, HDL; Computer Simulation; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Insulin; Kinetics; Leucine; Lipoproteins; Male; Middle Aged; Models, Biological; Reference Values; Software; Triglycerides | 2000 |
Leucine 7 to proline 7 polymorphism in the neuropeptide Y gene is associated with enhanced carotid atherosclerosis in elderly patients with type 2 diabetes and control subjects.
Topics: Aged; Amino Acid Substitution; Arteriosclerosis; Autonomic Nervous System; Blood Pressure; Carotid Stenosis; Cohort Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Genotype; Heart Rate; Humans; Leucine; Male; Neuropeptide Y; Polymorphism, Genetic; Proline; Risk Factors | 2000 |
Leucine 7 to proline 7 polymorphism in the neuropeptide y gene is associated with retinopathy in type 2 diabetes.
Topics: Aged; Amino Acid Substitution; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Finland; Follow-Up Studies; Glycated Hemoglobin; Humans; Leucine; Male; Middle Aged; Neuropeptide Y; Polymorphism, Genetic; Proline; Time Factors | 2000 |
Metabolic abnormalities of apolipoprotein B-containing lipoproteins in non-insulin-dependent diabetes: a stable isotope kinetic study.
Topics: Adult; Apolipoproteins B; Blood Glucose; Carbon Isotopes; Cholesterol; Diabetes Mellitus, Type 2; Female; Humans; Insulin; Kinetics; Leucine; Lipoproteins; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Middle Aged; Models, Biological | 2000 |
Intestinal aminooligopeptidase in diabetic BioBreed rat: altered posttranslational processing and trafficking.
Topics: Animals; CD13 Antigens; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Endoplasmic Reticulum; Enterocytes; Female; Glycosylation; Golgi Apparatus; Humans; Jejunum; Kinetics; Leucine; Male; Mannose; Methionine; Microvilli; Protein Processing, Post-Translational; Protein Transport; Rats; Rats, Inbred BB; Rats, Wistar; Sulfur Radioisotopes; Tritium | 2001 |
MODY associated with two novel hepatocyte nuclear factor-1alpha loss-of-function mutations (P112L and Q466X).
Topics: Diabetes Mellitus, Type 2; DNA; DNA Mutational Analysis; DNA-Binding Proteins; Female; Glutamine; HeLa Cells; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Hepatocytes; Humans; Immunohistochemistry; Leucine; Male; Mutagenesis, Site-Directed; Nuclear Proteins; Pedigree; Proline; Transcription Factors; Transcriptional Activation | 2000 |
beta-cell function and viability in the spontaneously diabetic GK rat: information from the GK/Par colony.
Topics: Animals; Apoptosis; Cell Count; Cell Survival; Diabetes Mellitus, Type 2; DNA; Female; Glucose; Glucose Transporter Type 2; Glucose-6-Phosphatase; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Mitotic Index; Monosaccharide Transport Proteins; Rats; Rats, Wistar; RNA, Messenger | 2001 |
Antiatherogenic mitochondrial genotype in patients with type 2 diabetes.
Topics: Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Arteriosclerosis; Carotid Stenosis; Diabetes Mellitus, Type 2; DNA, Mitochondrial; Female; Genomic Imprinting; Genotype; Humans; Japan; Leucine; Longevity; Male; Methionine; Middle Aged; Mutation, Missense; NADH Dehydrogenase; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Reference Values; Regression Analysis | 2001 |
A polymorphism in the 5' untranslated region and a Met229-->Leu variant in exon 5 of the human UCP1 gene are associated with susceptibility to type II diabetes mellitus.
Topics: 5' Untranslated Regions; Aged; Alleles; Amino Acid Substitution; Asian People; Carrier Proteins; Diabetes Mellitus, Type 2; Exons; Female; Gene Frequency; Genetic Predisposition to Disease; Genetic Variation; Genotype; Humans; Ion Channels; Japan; Leucine; Male; Membrane Proteins; Methionine; Middle Aged; Mitochondria; Mitochondrial Proteins; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Polymorphism, Single-Stranded Conformational; Reference Values; Uncoupling Protein 1 | 2001 |
A common phosphate binding site explains the unique substrate specificity of GSK3 and its inactivation by phosphorylation.
Topics: Amino Acid Sequence; Arginine; Axin Protein; beta Catenin; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cytoskeletal Proteins; Diabetes Mellitus, Type 2; Glycogen Synthase Kinase 3; Humans; Leucine; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphates; Phosphorylation; Protein Structure, Tertiary; Proteins; Repressor Proteins; Serine; Substrate Specificity; Trans-Activators | 2001 |
Type 2 diabetic patients may have a mild form of an injury response: a clinical research center study.
Topics: Acute-Phase Reaction; Adult; Blood Glucose; Body Weight; C-Peptide; Diabetes Mellitus, Type 2; Fasting; Glucagon; Gluconeogenesis; Humans; Hydrocortisone; Insulin; Interleukin-6; Leucine; Lung Neoplasms; Middle Aged; Triiodothyronine; Tumor Necrosis Factor-alpha | 2002 |
Increased urinary excretion of beta-hydroxyisovaleric acid in ketotic and non-ketotic type II diabetes mellitus.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Ketoacidosis; Female; Gas Chromatography-Mass Spectrometry; Glycosuria; Humans; Leucine; Male; Middle Aged; Trimethylsilyl Compounds; Valerates | 1990 |
Failure of glyburide and insulin treatment to decrease leucine flux in obese type II diabetic patients.
Topics: Diabetes Mellitus, Type 2; Female; Glyburide; Humans; Insulin; Leucine; Middle Aged; Obesity | 1990 |
Diurnal variation in glucose and leucine metabolism in non-insulin-dependent diabetes.
Topics: Adult; Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Female; Glucose; Growth Hormone; Humans; Hydrocortisone; Insulin; Leucine; Male; Metabolic Clearance Rate; Middle Aged; Reference Values | 1990 |
Long-term effect of insulin on glucose transport and insulin binding in cultured adipocytes from normal and obese humans with and without non-insulin-dependent diabetes.
Topics: Adipose Tissue; Adult; Binding, Competitive; Cells, Cultured; Diabetes Mellitus, Type 2; Female; Glucose; Humans; Insulin; Insulin Resistance; Leucine; Male; Obesity | 1987 |
Leucine metabolism in type II diabetes mellitus.
Topics: Adult; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Humans; Insulin; Leucine; Middle Aged; Obesity | 1986 |