leucine has been researched along with Degenerative Diseases, Central Nervous System in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 10 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Hu, J; Ji, L; Johnston, LJ; Liu, C; Ma, X; Zhang, X; Zhao, Y | 1 |
| Alexander, A; Dolga, AM; Galuh, S; Kortholt, A; Oun, A; Sabogal-Guaqueta, AM | 1 |
| Kim, YE; Kim, YJ; Lai, TT; Lee, YK; Ma, HI; Nguyen, HD; Nguyen, LTN; Nguyen, TT | 1 |
| Costa Valadão, PA; de Miranda, AS; de Oliveira Furlam, T; Guatimosim, C; Machado da Silva, EW; Roque, IG; Teixeira, AL; Vianna, PP | 1 |
| Charlet-Berguerand, N; Deng, J; Hong, D; Liufu, T; Meng, L; Wang, Z; Xu, J; Yu, J; Yuan, Y; Zhang, W; Zheng, Y | 1 |
| Chien, CT; Dewadas, HD; Foo, CN; Lim, YM; Lin, YE; Ravinther, AI; Tong, SR | 1 |
| Pan, AYH; Taylor, RM; Wade, CM; Williamson, P | 1 |
| Cao, R; Chen, C; Shan, L; Sun, H; Sun, L; Wen, J; Wu, C; Xi, M; Yuan, L; Zhang, C; Zhao, W | 1 |
| Duan, Y; Guo, Q; Li, F; Wang, W; Yang, Y; Yin, Y; Zhang, L; Zhong, Y | 1 |
| Belcher, G; Billington, I; Bremova-Ertl, T; Churchill, GC; Davis, W; Evans, W; Factor, M; Fields, T; Flint, S; Galione, A; Granzer, U; Greenfield, J; Karl, R; Kay, R; Lewi, D; Mathieson, T; Meyer, T; Pangonis, D; Patterson, M; Platt, FM; Strupp, M; Tsang, L; Verburg, C | 1 |
| Hibi, Y; Nabeshima, T; Nitta, A; Yamada, K | 1 |
| Bellen, HJ; Giagtzoglou, N; Ly, CV | 1 |
| Abascal-Palacios, G; Bonifacino, JS; Hierro, A; Kajava, A; Magadán, JG; Pérez-Victoria, FJ; Pioro, EP; Tascón, I | 1 |
| Britschgi, M; Johns, H; Masliah, E; Rockenstein, E; Takeda-Uchimura, Y; Wyss-Coray, T | 1 |
| Ghetti, B; Harris, DA; Piccardo, P; Stewart, RS | 1 |
9 review(s) available for leucine and Degenerative Diseases, Central Nervous System
| Article | Year |
|---|---|
Functional Amino Acids and Autophagy: Diverse Signal Transduction and Application.
Topics: Aging; Amino Acids; Arginine; Autophagy; Glutamine; Humans; Leucine; Mechanistic Target of Rapamycin Complex 1; Methionine; Neoplasms; Neurodegenerative Diseases; Obesity; Signal Transduction | 2021 |
The multifaceted role of LRRK2 in Parkinson's disease: From human iPSC to organoids.
Topics: Aged; Humans; Induced Pluripotent Stem Cells; Leucine; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mutation; Neurodegenerative Diseases; Organoids; Parkinson Disease | 2022 |
Role of NLRP3 Inflammasome in Parkinson's Disease and Therapeutic Considerations.
Topics: alpha-Synuclein; Cytokines; Humans; Inflammasomes; Inflammation; Leucine; Neurodegenerative Diseases; NLR Family, Pyrin Domain-Containing 3 Protein; Nucleotides; Parkinson Disease | 2022 |
Inflammasome activation and assembly in Huntington's disease.
Topics: Caspases; Humans; Huntington Disease; Inflammasomes; Interleukin-18; Interleukin-1beta; Leucine; Neurodegenerative Diseases; NLR Family, Pyrin Domain-Containing 3 Protein; Nucleotides | 2022 |
Molecular Pathways Involved in LRRK2-Linked Parkinson's Disease: A Systematic Review.
Topics: Humans; Leucine; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mutation; Neurodegenerative Diseases; Parkinson Disease | 2022 |
Recent advances in targeting leucine-rich repeat kinase 2 as a potential strategy for the treatment of Parkinson's disease.
Topics: Humans; Leucine; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mutation; Neurodegenerative Diseases; Parkinson Disease; Protein Serine-Threonine Kinases | 2023 |
Leucine Supplementation: A Novel Strategy for Modulating Lipid Metabolism and Energy Homeostasis.
Topics: AMP-Activated Protein Kinases; Animals; Anti-Obesity Agents; Cardiovascular Diseases; Diabetes Mellitus; Dietary Supplements; Energy Metabolism; Fatty Acids; Glucose Intolerance; Homeostasis; Humans; Insulin Resistance; Leucine; Lipid Metabolism; Lipolysis; Neurodegenerative Diseases; Nutritional Physiological Phenomena; Oxidation-Reduction; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Sirtuin 1 | 2020 |
[Possible relation of BDNF and GDNF to neuropsychiatric disorders].
Topics: Animals; Brain-Derived Neurotrophic Factor; Central Nervous System Agents; Chromatin Assembly and Disassembly; Cyclic AMP Response Element-Binding Protein; Dipeptides; Drug Design; Glial Cell Line-Derived Neurotrophic Factor; Histone Deacetylase Inhibitors; Humans; Isoleucine; Leucine; Mental Disorders; Neurodegenerative Diseases | 2009 |
Cell adhesion, the backbone of the synapse: "vertebrate" and "invertebrate" perspectives.
Topics: Animals; Cadherins; Cell Adhesion; Humans; Leucine; Mental Disorders; Models, Biological; Neurodegenerative Diseases; Neuronal Plasticity; Neurons; Synapses; Synaptic Transmission; Vertebrates | 2009 |
6 other study(ies) available for leucine and Degenerative Diseases, Central Nervous System
| Article | Year |
|---|---|
CGG repeat expansion in
Topics: 5' Untranslated Regions; Animals; Animals, Genetically Modified; Drosophila; Intranuclear Inclusion Bodies; Leucine; Mitochondria; Neurodegenerative Diseases; RNA-Binding Proteins; Trinucleotide Repeat Expansion | 2022 |
Cerebellar Abiotrophy in Australian Working Kelpies Is Associated with Two Major Risk Loci.
Topics: Animals; Australia; Cerebellar Ataxia; Cerebellar Diseases; Dog Diseases; Dogs; Genome-Wide Association Study; Leucine; Mammals; Membrane Proteins; Neurodegenerative Diseases | 2022 |
A master protocol to investigate a novel therapy acetyl-L-leucine for three ultra-rare neurodegenerative diseases: Niemann-Pick type C, the GM2 gangliosidoses, and ataxia telangiectasia.
Topics: Ataxia Telangiectasia; Female; Gangliosidoses, GM2; Humans; Leucine; Male; Neurodegenerative Diseases; Quality of Life | 2021 |
Structural basis for the wobbler mouse neurodegenerative disorder caused by mutation in the Vps54 subunit of the GARP complex.
Topics: Alleles; Amino Acid Sequence; Amino Acid Substitution; Animals; HeLa Cells; Humans; Leucine; Mice; Mice, Neurologic Mutants; Models, Molecular; Molecular Sequence Data; Multiprotein Complexes; Mutant Proteins; Mutation; Neurodegenerative Diseases; Organ Specificity; Protein Stability; Protein Structure, Quaternary; Protein Structure, Tertiary; Protein Subunits; Structure-Activity Relationship; Vesicular Transport Proteins | 2010 |
Deficiency of terminal complement pathway inhibitor promotes neuronal tau pathology and degeneration in mice.
Topics: Animals; Brain; CD59 Antigens; Disease Models, Animal; Green Fluorescent Proteins; Humans; Leucine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Nerve Tissue Proteins; Neurodegenerative Diseases; Neurons; Phosphorylation; Proline; Receptors, Complement; Signal Transduction; tau Proteins; Tauopathies | 2012 |
Neurodegenerative illness in transgenic mice expressing a transmembrane form of the prion protein.
Topics: Animals; Animals, Newborn; Arginine; Blotting, Western; Brain; Cells, Cultured; Cerebellum; Cricetinae; Cricetulus; Detergents; Disease Models, Animal; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique; Gene Expression; Glial Fibrillary Acidic Protein; Golgi Apparatus; Golgi Matrix Proteins; Immunoprecipitation; Leucine; Membrane Proteins; Methionine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neurodegenerative Diseases; Neurons; Octoxynol; Prion Diseases; Protein Structure, Tertiary; PrPSc Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfur Isotopes; Time Factors; Type C Phospholipases; Valine | 2005 |