leucine has been researched along with Cystic Fibrosis in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (28.00) | 18.7374 |
| 1990's | 7 (28.00) | 18.2507 |
| 2000's | 4 (16.00) | 29.6817 |
| 2010's | 6 (24.00) | 24.3611 |
| 2020's | 1 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| Almond, LM; Beringer, PM; Chung, PS; Hong, E; Rao, AP | 1 |
| Bedwell, DM; Bridges, RJ; Keeling, KM; Mobley, J; Mutyam, V; Rowe, SM; Thakerar, A; Xue, X | 1 |
| Bergbower, EAS; Boinot, C; Cebotaru, L; Guggino, WB; Liu, Q; Sabirzhanova, I; Yanda, MK | 1 |
| Aquino, RP; Del Gaudio, P; Mencherini, T; Russo, P; Sansone, F; Stigliani, M | 1 |
| Cutello, S; Di Dio, G; La Rosa, M; Leonardi, S; Parisi, GF; Rotolo, N | 1 |
| Hardin, DS; Rice, J; Rice, M; Switzer, M | 1 |
| Aquino, RP; Bifulco, M; Mencherini, T; Prota, L; Russo, P; Santoro, A | 1 |
| Aquino, RP; Auriemma, G; Crescenzi, C; Porta, A; Prota, L; Russo, P; Stigliani, M | 1 |
| Darmaun, D; Hayes, V; Mauras, N; Punati, J; Schaeffer, D | 1 |
| Darmaun, D; Hayes, V; Mauras, N; Schaeffer, D; Welch, S | 1 |
| Dean, RT; Jessup, W | 1 |
| Bussolati, O; Cabrini, G; Gazzola, GC; Rotoli, BM; Sironi, M | 1 |
| Denne, SC; Horswill, CA; Kien, CL; McCoy, KS; O'Dorisio, TM; Zipf, WB | 1 |
| Hardin, DS; LeBlanc, A; Lukenbaugh, S; Para, L; Seilheimer, DK | 1 |
| Akcakaya, N; Apak, M; Camcioglu, Y; Cokugras, H; Gokgoz, N; Kayserili, H; Kirdar, B; Onay, T; Topaloglu, O; Tsui, LC; Zielenski, J | 1 |
| Beldjord, C; Bienvenu, T; Bousquet, S; Cartault, F; Feingold, J; Lesure, F; McDonell, N; Renouil, M; Steffann, J; Vidaud, D | 1 |
| Denne, SC; Horswill, CA; Kien, CL; McCoy, KS; Zipf, WB | 1 |
| Berger, R; de Meer, K; Gulmans, V; Oostveen, D; van der Laag, J; van Doorn, J; Wattimena, D | 1 |
| Changus, JE; Pitot, HC; Quissell, DO; Sukup, MR | 1 |
| Baig, MM; Cetorelli, JJ; Roberts, RM | 1 |
| Collins, FS; Gibson, AL; Oxender, DL; Wagner, LM | 1 |
| Fletcher, DS | 1 |
| Barnett, DR; Bearn, AG; Bowman, BH; Danes, BS; Matalon, R | 1 |
| Falchuk, ZM; Taussig, LM | 1 |
| Authier, L; Desjeux, JF; Morin, CL | 1 |
1 trial(s) available for leucine and Cystic Fibrosis
| Article | Year |
|---|---|
Effects of glutamine and recombinant human growth hormone on protein metabolism in prepubertal children with cystic fibrosis.
Topics: Amino Acids; Blood Glucose; Body Composition; Child; Cystic Fibrosis; Drug Synergism; Energy Metabolism; Female; Glutamine; Growth Hormone; Humans; Leucine; Male; Malnutrition; Proteins | 2004 |
24 other study(ies) available for leucine and Cystic Fibrosis
| Article | Year |
|---|---|
Physiologically-Based Pharmacokinetic-Led Guidance for Patients With Cystic Fibrosis Taking Elexacaftor-Tezacaftor-Ivacaftor With Nirmatrelvir-Ritonavir for the Treatment of COVID-19.
Topics: Aminophenols; Benzodioxoles; Chloride Channel Agonists; COVID-19 Drug Treatment; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Cytochrome P-450 CYP3A; Drug Combinations; Drug Interactions; Humans; Indoles; Lactams; Leucine; Mutation; Nitriles; Proline; Pyrazoles; Pyridines; Pyrrolidines; Quinolines; Quinolones; Ritonavir | 2022 |
Identification of the amino acids inserted during suppression of CFTR nonsense mutations and determination of their functional consequences.
Topics: Amino Acids; Codon; Codon, Nonsense; Cysteine; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Genes, Suppressor; HEK293 Cells; Humans; Leucine; Mutation; Protein Biosynthesis; Tryptophan | 2017 |
Rescue of CFTR NBD2 mutants N1303K and S1235R is influenced by the functioning of the autophagosome.
Topics: Aminopyridines; Animals; Autophagosomes; Autophagy; Benzodioxoles; Biological Transport; Blotting, Western; Cell Line; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Electric Conductivity; Leucine; Mutant Proteins; Mutation; Small Molecule Libraries | 2018 |
Non-steroidal anti-inflammatory drug for pulmonary administration: design and investigation of ketoprofen lysinate fine dry powders.
Topics: Administration, Inhalation; Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differential Scanning; Cell Line; Cell Proliferation; Cystic Fibrosis; Drug Compounding; Drug Design; Dry Powder Inhalers; Humans; Ketoprofen; Leucine; Lysine; Microscopy, Electron, Scanning; Mucus; Particle Size; Powders | 2013 |
Phenotypic expression of the p.Leu1077Pro CFTR mutation in Sicilian cystic fibrosis patients.
Topics: Child; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Female; Gene Expression Regulation; Genotype; Heterozygote; Humans; Leucine; Male; Mutation; Phenotype; Proline; Pseudomonas aeruginosa; Pseudomonas Infections; Sicily; Young Adult | 2013 |
Insulin-like growth factor-I levels predict weight, height and protein catabolism in children and adolescents with cystic fibrosis.
Topics: Adolescent; Body Height; Body Weight; Child; Cystic Fibrosis; Female; Growth Disorders; Human Growth Hormone; Humans; Insulin-Like Growth Factor I; Leucine; Longitudinal Studies; Male; Proteins; Retrospective Studies; Treatment Outcome | 2009 |
Leucine enhances aerosol performance of naringin dry powder and its activity on cystic fibrosis airway epithelial cells.
Topics: Aerosols; Anti-Inflammatory Agents, Non-Steroidal; Bronchi; Cell Line; Cell Proliferation; Chemical Phenomena; Cystic Fibrosis; Epithelial Cells; Excipients; Flavanones; Humans; I-kappa B Kinase; I-kappa B Proteins; Leucine; MAP Kinase Signaling System; NF-kappa B; NF-KappaB Inhibitor alpha; Particle Size; Phosphorylation; Powders; Solubility; Surface Properties | 2011 |
Gentamicin and leucine inhalable powder: what about antipseudomonal activity and permeation through cystic fibrosis mucus?
Topics: Administration, Inhalation; Anti-Infective Agents; Cystic Fibrosis; Gentamicins; Leucine; Microbial Sensitivity Tests; Mucus; Particle Size; Permeability; Powders; Pseudomonas aeruginosa; Rheology; Technology, Pharmaceutical; Viscosity | 2013 |
Can glutamine and growth hormone promote protein anabolism in children with cystic fibrosis?
Topics: Bicarbonates; Carbon Isotopes; Child; Cystic Fibrosis; Female; Glutamine; Human Growth Hormone; Humans; Kinetics; Leucine; Male; Oxidation-Reduction; Protein Biosynthesis | 2002 |
Endocytosis and intracellular protein degradation in cystic fibrosis fibroblasts.
Topics: Cell Line; Cystic Fibrosis; Fibroblasts; Humans; Kinetics; Leucine; Pinocytosis; Proteins; Sucrose | 1983 |
CFTR protein is involved in the efflux of neutral amino acids.
Topics: Animals; Biological Transport; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Kinetics; Leucine; Membrane Proteins; Mice | 1994 |
Effects of feeding on protein turnover in healthy children and in children with cystic fibrosis.
Topics: Case-Control Studies; Child; Cystic Fibrosis; Dietary Proteins; Eating; Fasting; Female; Food, Formulated; Humans; Infusions, Intravenous; Insulin; Leucine; Male; Reference Values | 1996 |
Proteolysis associated with insulin resistance in cystic fibrosis.
Topics: Adolescent; Adult; Case-Control Studies; Cystic Fibrosis; Female; Glucose Tolerance Test; Humans; Hydrocortisone; Insulin; Insulin Resistance; Leucine; Male; Proteins | 1998 |
Analysis of the CFTR gene in Turkish cystic fibrosis patients: identification of three novel mutations (3172delAC, P1013L and M1028I).
Topics: Adenine; Amino Acid Substitution; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Cytosine; Frameshift Mutation; Humans; Isoleucine; Leucine; Methionine; Mutation; Polymorphism, Genetic; Proline; Sequence Deletion; Turkey | 1998 |
Detection of more than 91% cystic fibrosis mutations in a sample of the population from Reunion Island and identification of two novel mutations (A309G, S1255L) and one novel polymorphism (L49L)
Topics: Alanine; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; France; Glycine; Humans; Leucine; Mutation, Missense; Polymorphism, Genetic; Serine | 1998 |
Splanchnic uptake of leucine in healthy children and in children with cystic fibrosis.
Topics: Carbon Isotopes; Child; Cystic Fibrosis; Deuterium; Gas Chromatography-Mass Spectrometry; Humans; Intestinal Absorption; Leucine; Models, Biological; Reference Values; Splanchnic Circulation | 1999 |
Insulin-like growth factors and leucine kinetics during exercise training in children with cystic fibrosis.
Topics: Adolescent; Child; Cystic Fibrosis; Exercise; Female; Humans; Insulin-Like Growth Factor Binding Protein 3; Isotope Labeling; Leucine; Male; Nutritional Status; Prospective Studies; Somatomedins | 2001 |
Studies on the synthesis of plasma membrane proteins of fibroblasts from patients with cystic fibrosis.
Topics: Biopsy; Carbon Radioisotopes; Cell Membrane; Cells, Cultured; Cystic Fibrosis; Densitometry; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Genotype; Humans; In Vitro Techniques; Leucine; Protein Biosynthesis; Skin; Tritium | 1975 |
Plasma membrane components of skin fibroblasts from normal individuals and patients with cystic fibrosis.
Topics: Animals; Biopsy; Carbon Radioisotopes; Cattle; Cell Line; Cell Membrane; Centrifugation; Child; Child, Preschool; Cystic Fibrosis; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Fucose; Glucosamine; Glycoproteins; Heterozygote; Humans; Leucine; Proteins; Skin; Tritium | 1975 |
A bacterial system for investigating transport effects of cystic fibrosis--associated mutations.
Topics: Amino Acid Sequence; ATP-Binding Cassette Transporters; Bacterial Proteins; Biological Transport, Active; Cloning, Molecular; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; DNA Mutational Analysis; Escherichia coli; Escherichia coli Proteins; Humans; Kinetics; Leucine; Membrane Proteins; Membrane Transport Proteins; Molecular Sequence Data; Protein Binding; Restriction Mapping; Sequence Alignment; Structure-Activity Relationship | 1991 |
Incorporation of L-leucine and D-glucosamine into skin fibroblasts derived from cystic fibrosis and normal individuals.
Topics: Adenosine Triphosphatases; Amino Acids; Aminobutyrates; Calcium; Carbon Isotopes; Cells, Cultured; Cystic Fibrosis; Electrophoresis; Fibroblasts; Glucosamine; Humans; In Vitro Techniques; Iodoacetates; Kinetics; Leucine; Potassium; Skin; Sodium; Sodium Dodecyl Sulfate; Subcellular Fractions; Tritium | 1973 |
Cystic fibrosis: fractionation of fibroblast media demonstrating ciliary inhibition.
Topics: Animals; Biological Assay; Carbon Isotopes; Cells, Cultured; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cilia; Culture Media; Cystic Fibrosis; Fibroblasts; Heterozygote; Humans; Leucine; Molecular Weight; Ostreidae; Protein Biosynthesis; Proteins | 1973 |
IgA synthesis by jejunal biopsies from patients with cystic fibrosis and hereditary pancreatitis.
Topics: Adolescent; Adult; Biopsy; Carbon Isotopes; Carboxypeptidases; Chymotrypsin; Cystic Fibrosis; Female; Humans; Immunoglobulin A; In Vitro Techniques; Intestinal Mucosa; Jejunum; Leucine; Male; Pancreatitis; Trypsin | 1973 |
Effect of saliva and serum from patients with cystic fibrosis on intestinal uptake of amino acids in rat.
Topics: Alanine; Amino Acids; Animals; Biological Transport; Blood; Child; Child, Preschool; Cystic Fibrosis; Humans; Intestinal Mucosa; Leucine; Rats; Saliva; Time Factors | 1973 |