leucine and Cirrhosis

leucine has been researched along with Cirrhosis in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (35.00)29.6817
2010's7 (35.00)24.3611
2020's6 (30.00)2.80

Authors

AuthorsStudies
Cai, G; Cai, H; Chen, XM; He, JC; Hong, Q; Lee, K; Li, Z; Ni, Z; Zhang, L; Zhong, F1
Fan, G; Feng, F; Liu, J; Meng, C; Sun, T; Tao, N1
Chen, X; Hou, L; Hu, G; Huo, C; Li, C; Li, X; Wang, L; Wang, N; Wang, X; Xu, R; Zhang, F1
Hu, X; Ning, F; Reilly, S; Wang, M; Wu, T; Xin, H; Zhang, X; Zhou, S1
Biswas, S; Chakraborty, D; Kumar, V; Malhotra, R; Sarkar, A1
de Hart, NM; Drummond, MJ; Eshima, H; Ferrara, PJ; Fix, DK; Funai, K; Kelley, JJ; Mahmassani, ZS; McKenzie, AI; Montgomery, JA; Petrocelli, JJ; Reidy, PT1
Asatryan, A; Beyer, J; Campbell, A; Collins, C; Dekhtyar, T; Irvin, M; Kort, J; Krishnan, P; Lawitz, EJ; Lovell, S; Lu, L; Mensa, F; Ng, TI; Pilot-Matias, T; Reisch, T; Schnell, G; Tripathi, R; Yao, B1
Liu, W; Lovell, S; Mensa, FJ; Pilot-Matias, T1
Aguilar, H; Asatryan, A; Gane, E; Hassanein, T; Kort, J; Kwo, PY; Lalezari, J; Lin, CW; Liu, R; Maliakkal, B; Mensa, FJ; Ng, TI; Poordad, F; Wang, S; Wyles, DL1
Cheng, XW; Izawa, H; Kim, W; Kobayashi, M; Kuzuya, M; Murohara, T; Nagata, K; Nishizawa, T; Obata, K; Okumura, K; Sasaki, T; Sato, K; Shi, GP; Yamada, T; Yokota, M1
Hosoya, T; Ikeda, K; Ishikawa, M; Kawamura, M; Nakao, K; Otsubo, C; Tajima, N; Tojo, K; Tokudome, G; Udagawa, T1
Chappell, MC; Ferrario, CM; Gallagher, PE; Ganten, D; Groban, L; Trask, AJ; Varagic, J; Westwood, BM1
Acuña, MJ; Brandan, E; Cabello-Verrugio, C; Cofré, C; Melo, F; Santander, C1
McGaffin, KR; Witham, WG; Yester, KA1
Garcia, JG; Gupta, MP; Kim, G; Moreno-Vinasco, L; Pillai, VB; Samant, S; Sundaresan, NR1
Eismann, U; Gerth, J; Sommer, M; Stein, G1
Kawahara, Y; Maki, T; Takeo, S; Tanonaka, K; Yagi, A1
Weber, KT1
Asbun, J; Manso, AM; Villarreal, FJ1
Chappell, MC; Ferrario, CM; Garabelli, PJ; Modrall, JG; Penninger, JM1

Reviews

2 review(s) available for leucine and Cirrhosis

ArticleYear
Emerging role for branched-chain amino acids metabolism in fibrosis.
    Pharmacological research, 2023, Volume: 187

    Topics: Amino Acids, Branched-Chain; Fibrosis; Humans; Isoleucine; Leucine; Valine

2023
Glecaprevir/pibrentasvir for the treatment of chronic hepatitis C virus infection.
    Future microbiology, 2019, Volume: 14

    Topics: Aminoisobutyric Acids; Antiviral Agents; Benzimidazoles; Coinfection; Cyclopropanes; Drug Interactions; Drug Therapy, Combination; Drug Tolerance; Fibrosis; Hepacivirus; Hepatitis C, Chronic; HIV; HIV Infections; Humans; Lactams, Macrocyclic; Leucine; Proline; Protease Inhibitors; Pyrrolidines; Quinoxalines; Renal Insufficiency, Chronic; Sulfonamides; Treatment Outcome

2019

Trials

2 trial(s) available for leucine and Cirrhosis

ArticleYear
Resistance Analysis of a 3-Day Monotherapy Study with Glecaprevir or Pibrentasvir in Patients with Chronic Hepatitis C Virus Genotype 1 Infection.
    Viruses, 2018, 08-28, Volume: 10, Issue:9

    Topics: Amino Acid Substitution; Aminoisobutyric Acids; Antiviral Agents; Benzimidazoles; Cyclopropanes; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; Fibrosis; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Lactams, Macrocyclic; Leucine; Liver; Proline; Pyrrolidines; Quinoxalines; RNA, Viral; Sulfonamides; Viral Load

2018
High Efficacy of ABT-493 and ABT-530 Treatment in Patients With HCV Genotype 1 or 3 Infection and Compensated Cirrhosis.
    Gastroenterology, 2016, Volume: 151, Issue:4

    Topics: Aminoisobutyric Acids; Antiviral Agents; Benzimidazoles; Cyclopropanes; Drug Therapy, Combination; Female; Fibrosis; Genotype; Hepacivirus; Hepatitis C; Humans; Lactams, Macrocyclic; Leucine; Male; Middle Aged; Proline; Pyrrolidines; Quinoxalines; Ribavirin; Sulfonamides; Sustained Virologic Response

2016

Other Studies

16 other study(ies) available for leucine and Cirrhosis

ArticleYear
Modulation of transforming growth factor-β-induced kidney fibrosis by leucine-rich ⍺-2 glycoprotein-1.
    Kidney international, 2022, Volume: 101, Issue:2

    Topics: Animals; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Endothelial Cells; Fibrosis; Glycoproteins; Humans; Kidney; Leucine; Mice; Smad3 Protein; Transforming Growth Factor beta; Transforming Growth Factor beta1; Transforming Growth Factors; Ureteral Obstruction

2022
Ginsenoside Rb1 Alleviates Bleomycin-Induced Pulmonary Inflammation and Fibrosis by Suppressing Central Nucleotide-Binding Oligomerization-, Leucine-Rich Repeat-, and Pyrin Domains-Containing Protein Three Inflammasome Activation and the NF-κB Pathway.
    Drug design, development and therapy, 2022, Volume: 16

    Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Bleomycin; Fibrosis; Ginsenosides; Idiopathic Pulmonary Fibrosis; Inflammasomes; Interleukin-1beta; Leucine; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Nucleotides; Pneumonia; Pyrin Domain; Signal Transduction

2022
LRRC8A critically regulates myofibroblast phenotypes and fibrotic remodeling following myocardial infarction.
    Theranostics, 2022, Volume: 12, Issue:13

    Topics: Animals; Carrier Proteins; Fibrosis; Leucine; Membrane Proteins; Mice; Myocardial Infarction; Myofibroblasts; Phenotype; Transforming Growth Factor beta1

2022
Upregulation of leucine-rich alpha-2 glycoprotein: A key regulator of inflammation and joint fibrosis in patients with severe knee osteoarthritis.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Fibrosis; Glycoproteins; Humans; Inflammation; Knee Joint; Leucine; Osteoarthritis, Knee; Proteomics; Up-Regulation

2022
Metformin and leucine increase satellite cells and collagen remodeling during disuse and recovery in aged muscle.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2021, Volume: 35, Issue:9

    Topics: Aging; AMP-Activated Protein Kinases; Animals; Body Weight; Collagen; Fibrosis; Hindlimb Suspension; Immunoglobulin G; Leucine; Male; Mechanistic Target of Rapamycin Complex 1; Metformin; Mice; Mice, Inbred C57BL; Muscle Development; Muscle Fibers, Skeletal; Muscle Strength; Muscle, Skeletal; Muscular Atrophy; Organ Size; RNA-Seq; Satellite Cells, Skeletal Muscle; Signal Transduction

2021
Superoxide-dependent cathepsin activation is associated with hypertensive myocardial remodeling and represents a target for angiotensin II type 1 receptor blocker treatment.
    The American journal of pathology, 2008, Volume: 173, Issue:2

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Cathepsins; Cells, Cultured; Fibrosis; Heart Failure; Humans; Hypertension; Imidazoles; Leucine; Myocardium; Myocytes, Cardiac; NADPH Oxidases; Rats; Rats, Inbred Dahl; Receptor, Angiotensin, Type 1; Sodium Chloride; Superoxides; Tetrazoles; Ventricular Remodeling

2008
Cellular physiology of rat cardiac myocytes in cardiac fibrosis: in vitro simulation using the cardiac myocyte/cardiac non-myocyte co-culture system.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2008, Volume: 31, Issue:4

    Topics: Angiotensin II; Angiotensinogen; Animals; Animals, Newborn; Atrial Natriuretic Factor; Cardiomegaly; Cell Separation; Cells, Cultured; Coculture Techniques; Diuretics, Osmotic; Endothelin-1; Fibrosis; Leucine; Mannitol; Myocardium; Myocytes, Cardiac; Natriuretic Peptide, Brain; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Receptors, Angiotensin; Renin; Thymidine; Transforming Growth Factor beta1; Tritium

2008
Inhibition of angiotensin-converting enzyme 2 exacerbates cardiac hypertrophy and fibrosis in Ren-2 hypertensive rats.
    American journal of hypertension, 2010, Volume: 23, Issue:6

    Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cardiomegaly; Fibrosis; Heart Ventricles; Imidazoles; Leucine; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Transgenic

2010
The internal region leucine-rich repeat 6 of decorin interacts with low density lipoprotein receptor-related protein-1, modulates transforming growth factor (TGF)-β-dependent signaling, and inhibits TGF-β-dependent fibrotic response in skeletal muscles.
    The Journal of biological chemistry, 2012, Feb-24, Volume: 287, Issue:9

    Topics: Animals; Cell Line; CHO Cells; Cricetinae; Decorin; Endocytosis; Fibrosis; Glyburide; Humans; Leucine; Low Density Lipoprotein Receptor-Related Protein-1; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Myoblasts, Skeletal; Protein Structure, Tertiary; Signal Transduction; Transforming Growth Factor beta

2012
A high leucine diet mitigates cardiac injury and improves survival after acute myocardial infarction.
    Metabolism: clinical and experimental, 2013, Volume: 62, Issue:2

    Topics: Animals; Apoptosis; Cardiomegaly; Echocardiography; Extracellular Signal-Regulated MAP Kinases; Fibrosis; Histocytochemistry; Kaplan-Meier Estimate; Leucine; Male; Mice; Mice, Inbred C57BL; Myocardial Infarction; Random Allocation; Signal Transduction; TOR Serine-Threonine Kinases

2013
Nampt secreted from cardiomyocytes promotes development of cardiac hypertrophy and adverse ventricular remodeling.
    American journal of physiology. Heart and circulatory physiology, 2013, Feb-01, Volume: 304, Issue:3

    Topics: Animals; Animals, Newborn; Cardiomegaly; Coloring Agents; Echocardiography; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Fibrosis; Immunohistochemistry; Leucine; Mice; Mice, Knockout; Mice, Transgenic; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; NFATC Transcription Factors; Nicotinamide Phosphoribosyltransferase; Rats; Real-Time Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tetrazolium Salts; Thiazoles; Ventricular Remodeling

2013
Interleukin 4 co-stimulates the PDGF-BB- and bFGF-mediated proliferation of mesangial cells and myofibroblasts.
    Nephron, 2002, Volume: 92, Issue:4

    Topics: Animals; Becaplermin; Cattle; Cell Differentiation; Cell Division; Cells, Cultured; Fibroblast Growth Factor 2; Fibroblasts; Fibrosis; Glomerular Mesangium; Humans; Interleukin-4; Kidney Tubules; Leucine; Platelet-Derived Growth Factor; Proline; Proto-Oncogene Proteins c-sis

2002
Effects of tanshinone VI on the hypertrophy of cardiac myocytes and fibrosis of cardiac fibroblasts of neonatal rats.
    Planta medica, 2002, Volume: 68, Issue:12

    Topics: Animals; Animals, Newborn; Cardiomegaly; Cells, Cultured; Collagen; Endothelin-1; Female; Fibroblasts; Fibrosis; Insulin-Like Growth Factor I; Leucine; Male; Myocytes, Cardiac; Paracrine Communication; Phenanthrenes; Phenylephrine; Plant Extracts; Plant Roots; Rats; Rats, Wistar; Salvia miltiorrhiza; Tritium

2002
Fibrosis in hypertensive heart disease: focus on cardiac fibroblasts.
    Journal of hypertension, 2004, Volume: 22, Issue:1

    Topics: Aminopeptidases; Angiotensin-Converting Enzyme Inhibitors; Animals; Collagen; Fibroblasts; Fibrosis; Heart Diseases; Humans; Hypertension; Leucine; Lisinopril; Myocardium; Peptidyl-Dipeptidase A; Protease Inhibitors

2004
Profibrotic influence of high glucose concentration on cardiac fibroblast functions: effects of losartan and vitamin E.
    American journal of physiology. Heart and circulatory physiology, 2005, Volume: 288, Issue:1

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Cells, Cultured; Collagen Type I; Dose-Response Relationship, Drug; Fibroblasts; Fibrosis; Glucose; Leucine; Losartan; Male; Matrix Metalloproteinases; Myocardium; Osmolar Concentration; Proline; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; RNA, Messenger; Vitamin E

2005
Distinct roles for angiotensin-converting enzyme 2 and carboxypeptidase A in the processing of angiotensins within the murine heart.
    Experimental physiology, 2008, Volume: 93, Issue:5

    Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Carboxypeptidases A; Cell Proliferation; Fibrosis; Heart; Imidazoles; Immunohistochemistry; Leucine; Male; Membranes; Mice; Mice, Knockout; Myocardium; Peptide Fragments; Peptidyl-Dipeptidase A; Protease Inhibitors; Succinates

2008