leucine has been researched along with Chromosome Deletion in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (23.81) | 18.7374 |
| 1990's | 5 (23.81) | 18.2507 |
| 2000's | 3 (14.29) | 29.6817 |
| 2010's | 7 (33.33) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Loutaev, I; Saré, RM; Smith, CB; Torossian, A | 1 |
| Bello, E; Boultwood, J; Kerry, J; Killick, S; Kušec, R; Pellagatti, A; Raynaud, S; Singh, S; Yip, BH | 1 |
| Ebert, BL; Steensma, DP | 1 |
| Abayasekara, N; Berliner, N; Ebert, BL; Hurst, SN; Khanna-Gupta, A; Look, AT; Narla, A; Payne, EM; Raiser, DM | 1 |
| Dornhoffer, J; Hartzell, LD; McKelvey, KD; Van Hemert, RL | 1 |
| Boultwood, J; Fernandez-Mercado, M; Germing, U; Giagounidis, A; Killick, S; Lamikanra, AA; McDonald, EJ; Pellagatti, A; Roberts, DJ; Vuppusetty, C; Wainscoat, JS; Yip, BH | 1 |
| Berliner, N; Ebert, BL; Khanna-Gupta, A; Levine, M; Look, AT; Narla, A; Paw, BH; Payne, EM; Sun, H; Virgilio, M | 1 |
| Boultwood, J; Pellagatti, A; Vuppusetty, C; Wainscoat, JS; Yip, BH | 1 |
| Attwood, M; Boultwood, J; Germing, U; Giagounidis, A; Lamikanra, AA; Maciejewski, JP; Mecucci, C; Pellagatti, A; Roberts, DJ; Vandenberghe, P; Vuppusetty, C; Wainscoat, JS; Yip, BH | 1 |
| Burke, DW; Butler, MG; Campbell, CA; Chang, EH; Forrester, S; Hoppe, JE; Schneider, MC; Smith, LL; Smith, RJ; Vore, AP | 1 |
| Szostak, JW; Wu, R | 1 |
| Alagille, D; Borghi, E; Deleuze, JF; Deschatrette, J; Dhorne, S; Hadchouel, M; Hazan, J; Meunier-Rotival, M; Pollet, N; Raynaud, N | 1 |
| Bloecher, A; Knatko, EV; MacKelvie, SH; Peggie, MW; Stark, MJ; Tatchell, K | 1 |
| Brennan, SO; George, PM; Higuchi, R; Myles, T; Symmans, WA; Williamson, D | 1 |
| Allen, J; Brennan, SO; George, PM; Shaw, J | 1 |
| Paluh, JL; Yanofsky, C | 1 |
| Brisco, PR; Kohlhaw, GB | 1 |
| Friden, P; Reynolds, C; Schimmel, P | 1 |
| Friden, P; Schimmel, P | 1 |
| Hughes, KT; Roth, JR | 1 |
| Calvo, JM; De Felice, M; Haughn, GW; Largo, CT; Squires, CH | 1 |
1 review(s) available for leucine and Chromosome Deletion
| Article | Year |
|---|---|
Activation of the mTOR pathway by the amino acid (L)-leucine in the 5q- syndrome and other ribosomopathies.
Topics: Anemia, Diamond-Blackfan; Anemia, Macrocytic; Animals; Chromosome Deletion; Chromosomes, Human, Pair 5; Erythroblasts; Gene Expression Regulation; Haploinsufficiency; Humans; Leucine; Protein Biosynthesis; Ribosomal Proteins; Ribosomes; Signal Transduction; TOR Serine-Threonine Kinases | 2013 |
20 other study(ies) available for leucine and Chromosome Deletion
| Article | Year |
|---|---|
Increased rates of cerebral protein synthesis in Shank3 knockout mice: Implications for a link between synaptic protein deficit and dysregulated protein synthesis in autism spectrum disorder/intellectual disability.
Topics: Animals; Autism Spectrum Disorder; Autoradiography; Brain; Carbon Radioisotopes; Chromosome Deletion; Chromosome Disorders; Chromosomes, Human, Pair 22; Disease Models, Animal; Intellectual Disability; Leucine; Mice; Mice, Knockout; Microfilament Proteins; Nerve Tissue Proteins; Protein Biosynthesis; Synaptosomes | 2021 |
L-leucine increases translation of
Topics: Autoantigens; Cells, Cultured; Chromosome Deletion; Chromosomes, Human, Pair 5; Erythroblasts; Female; Humans; Leucine; Male; Myelodysplastic Syndromes; Protein Biosynthesis; Ribonucleoproteins; Ribosomal Proteins; SS-B Antigen | 2018 |
Initial experience with L-leucine therapy in myelodysplastic syndromes with associated chromosome 5q deletion.
Topics: Aged; Chromosome Deletion; Chromosomes, Human, Pair 5; Female; Humans; Leucine; Male; Middle Aged; Myelodysplastic Syndromes; Treatment Outcome | 2013 |
L-Leucine improves the anaemia in models of Diamond Blackfan anaemia and the 5q- syndrome in a TP53-independent way.
Topics: Anemia, Diamond-Blackfan; Anemia, Macrocytic; Animals; Chromosome Deletion; Chromosomes, Human, Pair 5; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; Humans; Leucine; Ribosomal Proteins; Tumor Suppressor Protein p53; Zebrafish Proteins | 2014 |
Cerebellopontine angle tumor in a patient with a maternally inherited SDHD gene mutation.
Topics: Alleles; Amino Acid Substitution; Base Sequence; Cerebellar Neoplasms; Cerebellopontine Angle; Chromosome Deletion; Codon; Diagnosis, Differential; DNA Mutational Analysis; Genetic Predisposition to Disease; Genotype; Humans; Leucine; Neoplasms, Multiple Primary; Neuroma, Acoustic; Paraganglioma; Proline; Radiography; Radiosurgery; Succinate Dehydrogenase | 2008 |
Effects of L-leucine in 5q- syndrome and other RPS14-deficient erythroblasts.
Topics: Anemia, Macrocytic; Case-Control Studies; Cell Differentiation; Cell Proliferation; Chromosome Deletion; Chromosomes, Human, Pair 5; Cri-du-Chat Syndrome; Erythroblasts; Flow Cytometry; Humans; Leucine; Polymerase Chain Reaction; Protein Biosynthesis; Ribosomal Proteins; RNA, Messenger; RNA, Small Interfering; Trisomy | 2012 |
L-Leucine improves the anemia and developmental defects associated with Diamond-Blackfan anemia and del(5q) MDS by activating the mTOR pathway.
Topics: Anemia, Diamond-Blackfan; Anemia, Macrocytic; Animals; Animals, Genetically Modified; Cells, Cultured; Chromosome Deletion; Chromosomes, Human, Pair 5; Disease Models, Animal; Embryo, Nonmammalian; Embryonic Development; Hematinics; Hematopoiesis; Hematopoietic Stem Cells; Humans; Leucine; Myelodysplastic Syndromes; Ribosomal Proteins; RNA, Small Interfering; Signal Transduction; TOR Serine-Threonine Kinases; Up-Regulation; Zebrafish; Zebrafish Proteins | 2012 |
Activation of the mTOR signaling pathway by L-leucine in 5q- syndrome and other RPS14-deficient erythroblasts.
Topics: Anemia, Macrocytic; Chromosome Deletion; Chromosomes, Human, Pair 5; Enzyme Activation; Erythroblasts; Humans; Leucine; Ribosomal Proteins; Signal Transduction; TOR Serine-Threonine Kinases | 2013 |
Deletion of and novel missense mutation in POU3F4 in 2 families segregating X-linked nonsyndromic deafness.
Topics: Chromosome Deletion; Chromosome Segregation; Deafness; Female; Genetic Diseases, X-Linked; Humans; Leucine; Male; Mutation, Missense; Pedigree; POU Domain Factors; Sensory Thresholds; Serine; Temporal Bone; Tomography, X-Ray Computed | 2005 |
Unequal crossing over in the ribosomal DNA of Saccharomyces cerevisiae.
Topics: Chromosome Deletion; Crossing Over, Genetic; DNA Replication; DNA, Fungal; Genes; Genetic Linkage; Leucine; Mitosis; Plasmids; RNA, Ribosomal; Saccharomyces cerevisiae; Sister Chromatid Exchange | 1980 |
Deleted chromosome 20 from a patient with Alagille syndrome isolated in a cell hybrid through leucine transport selection: study of three candidate genes.
Topics: Alagille Syndrome; Animals; CHO Cells; Chromosome Deletion; Chromosomes, Human, Pair 20; Cricetinae; Cricetulus; Cystatin C; Cystatins; DNA-Binding Proteins; Genes; Hepatocyte Nuclear Factor 3-beta; Humans; Hybrid Cells; In Situ Hybridization, Fluorescence; Leucine; Leucine-tRNA Ligase; Lymphocytes; Nuclear Proteins; Paired Box Transcription Factors; Selection, Genetic; Transcription Factors | 1994 |
Essential functions of Sds22p in chromosome stability and nuclear localization of PP1.
Topics: Alleles; Amino Acid Sequence; Blotting, Western; Catalytic Domain; Cell Cycle Proteins; Cell Nucleus; Chromosome Deletion; Chromosomes, Fungal; Conserved Sequence; Fungal Proteins; Leucine; Microscopy, Fluorescence; Mutation; Nuclear Proteins; Phosphoprotein Phosphatases; Plasmids; Protein Phosphatase 1; Repetitive Sequences, Amino Acid; Saccharomyces cerevisiae; Schizosaccharomyces pombe Proteins; Temperature; Transformation, Genetic | 2002 |
A family with haemolytic anaemia and three beta-globins: the deletion in haemoglobin Atlanta-Coventry (beta 75 Leu----Pro, 141 Leu deleted) is not present at the nucleotide level.
Topics: Anemia, Hemolytic; Base Sequence; Blotting, Southern; Chromosome Deletion; Codon; DNA; Female; Globins; Hemoglobins, Abnormal; Humans; Leucine; Male; Molecular Sequence Data; Mutation; Pedigree; Polymerase Chain Reaction; Proline; RNA, Messenger | 1992 |
Beta 141 Leu is not deleted in the unstable haemoglobin Atlanta-Coventry but is replaced by a novel amino acid of mass 129 daltons.
Topics: Amino Acid Sequence; Anemia, Hemolytic; Chromosome Deletion; Codon; DNA; Globins; Hemoglobins, Abnormal; Humans; Leucine; Mass Spectrometry; Molecular Sequence Data; Molecular Weight; Mutation | 1992 |
Characterization of Neurospora CPC1, a bZIP DNA-binding protein that does not require aligned heptad leucines for dimerization.
Topics: Amino Acid Sequence; Base Sequence; Chimera; Chromosome Deletion; DNA-Binding Proteins; Fungal Proteins; Gene Expression Regulation, Fungal; Genes, Fungal; Leucine; Macromolecular Substances; Models, Molecular; Molecular Sequence Data; Neurospora crassa; Oligonucleotide Probes; Protein Conformation; Restriction Mapping; Transcription, Genetic | 1991 |
Regulation of yeast LEU2. Total deletion of regulatory gene LEU3 unmasks GCN4-dependent basal level expression of LEU2.
Topics: 2-Isopropylmalate Synthase; Base Sequence; Chromosome Deletion; Escherichia coli; Gene Expression Regulation, Fungal; Genes, Fungal; Genes, Regulator; Leucine; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Phenotype; Plasmids; Recombinant Fusion Proteins; Restriction Mapping; Saccharomyces cerevisiae | 1990 |
A large internal deletion converts yeast LEU3 to a constitutive transcriptional activator.
Topics: Chromosome Deletion; DNA, Fungal; Gene Expression Regulation; Genes, Fungal; Genes, Regulator; Leucine; Malates; Saccharomyces cerevisiae; Transcription, Genetic | 1989 |
LEU3 of Saccharomyces cerevisiae encodes a factor for control of RNA levels of a group of leucine-specific genes.
Topics: Amino Acid Sequence; Base Sequence; Chromosome Deletion; DNA Restriction Enzymes; DNA-Binding Proteins; Fungal Proteins; Gene Expression Regulation; Genes, Fungal; Leucine; Nucleic Acid Hybridization; Plasmids; RNA, Fungal; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Trans-Activators | 1987 |
Directed formation of deletions and duplications using Mud(Ap, lac).
Topics: Bacterial Proteins; Bacteriophage mu; Chromosome Deletion; DNA, Bacterial; DNA, Viral; Genes, Bacterial; Genetic Engineering; Histidine; Leucine; Mutation; Operon; Recombination, Genetic; Salmonella typhimurium; Threonine; Translocation, Genetic | 1985 |
Unusual organization of the ilvIH promoter of Escherichia coli.
Topics: Base Sequence; Chromosome Deletion; Chromosome Mapping; DNA, Bacterial; Escherichia coli; Gene Expression Regulation; Isoleucine; Leucine; Molecular Sequence Data; Mutation; Operon; Promoter Regions, Genetic; RNA, Messenger; Transcription, Genetic; Valine | 1985 |