leucine has been researched along with Chemical and Drug Induced Liver Injury in 33 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 27 (81.82) | 18.7374 |
1990's | 3 (9.09) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 3 (9.09) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
Calado, RT; Clé, DV | 1 |
Agundez, JA; Andrade, RJ; Borraz, Y; Castiella, A; De Dios, AM; Durán, JA; Fernandez, MC; García-Martín, E; Guarner, C; Lucena, MI; Martínez, C; Planas, R; Romero-Gomez, M; Ruiz, JD; Soriano, G; Stephens, C; Ulzurrun, E | 1 |
AFZELIUS, BA; ARRHENIUS, E; GUSTAFSSON, RG; MUKHERJEE, T | 1 |
ANAGNOSTOU, E; HADZIYANNIS, S; KAKARI, S; MERICAS, G | 1 |
MONDEN, M | 1 |
BORNSTEIN, S; HALBREICH, A; MAGER, J | 1 |
ASHWORTH, CT; WERNER, JD; WRIGHTSMAN, FJ | 1 |
Alldridge, WN; Witschi, HP | 1 |
Clifford, JI; Rees, KR | 1 |
Ito, K; Tatsuno, T; Ueno, I; Ueno, Y | 1 |
Carmel, N; Hershko, C; Konijn, AM; Levy, R | 1 |
Castro, JA; Díaz Gómez, MI; Galelli, M | 1 |
Carter, EA; Dienstag, JL; Fischer, JE; Isselbacher, KJ; Wands, JR | 1 |
Kodama, K; Oguchi, K; Tsuji, M | 1 |
Arai, M; Fukushima, K; Kohno, Y; Satoh, T; Suwa, T | 1 |
Bernacchi, AS; Castro, JA; de Castro, CR; de Fenos, OM; de Ferreyra, EC; Fernández, G; Villarruel, MC | 1 |
Okita, M; Tsuji, T; Watanabe, A | 1 |
Nagashima, H; Ukida, M; Usui, H | 1 |
Cooksley, WG; Halliday, JW; Mack, U; Owens, J; Powell, LW | 1 |
Gordon, AH; Koj, A | 1 |
Healy, PJ | 2 |
Leduc, LH | 1 |
Bolmey, S; Kaltenbach, JP | 1 |
Bertolino, A; Giovine, A; Renis, M; Rizzi, MM | 1 |
Scholler, KL | 1 |
Goldman, M; Griffin, AC | 1 |
Farber, E; Liang, H; Reid, IM; Shinozuka, H; Shull, KH | 1 |
Albano, O; Francavilla, A | 1 |
Leaver, DD; Villa-Treviño, S | 1 |
Kanics, L; Rubinstein, D | 1 |
Robinson, DS; Seakins, A | 1 |
1 review(s) available for leucine and Chemical and Drug Induced Liver Injury
Article | Year |
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Treatment of inherited bone marrow failure syndromes beyond transplantation.
Topics: Androgens; Bone Marrow Diseases; Chemical and Drug Induced Liver Injury; Danazol; Female; Genetic Diseases, Inborn; Genetic Therapy; Humans; Leucine; Oxymetholone; Quercetin; Stem Cell Transplantation; Syndrome; Virilism | 2017 |
32 other study(ies) available for leucine and Chemical and Drug Induced Liver Injury
Article | Year |
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Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitochondrial superoxide dismutase and glutathione peroxidase in idiosyncratic drug-induced liver injury.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alleles; Amino Acid Substitution; Chemical and Drug Induced Liver Injury; Female; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; Leucine; Male; Middle Aged; Mitochondria; Polymorphism, Genetic; Superoxide Dismutase; Young Adult | 2010 |
EFFECTS OF CARCINOGENIC AMINES ON AMINO ACID INCORPORATION BY LIVER SYSTEMS. II. A MORPHOLOGICAL AND BIOCHEMICAL STUDY ON THE EFFECT OF DIMETHYLNITROSAMINE.
Topics: Amines; Amino Acids; Carbon Isotopes; Carcinogens; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Electrons; Hepatitis; Leucine; Liver; Liver Glycogen; Liver Neoplasms; Microscopy; Microscopy, Electron; Mitochondria; Nitrosamines; Proteins; Rats; Research; Toxicology | 1963 |
THE DIAGNOSTIC VALUE OF SERUM LEUCINE AMINOPEPTIDASE.
Topics: Adolescent; Aminopeptidases; Chemical and Drug Induced Liver Injury; Child; Cholecystitis; Cholelithiasis; Clinical Enzyme Tests; Gallstones; Geriatrics; Hepatitis; Hepatitis A; Jaundice; Jaundice, Obstructive; Leucine; Leucyl Aminopeptidase; Liver Neoplasms; Neoplasm Metastasis; Pancreatic Neoplasms | 1964 |
[A STUDY OF THE FREE AMINO ACIDS IN THE SERUM OF LIVER DISEASES].
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Blood; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Dogs; Glutamates; Glycine; Hepatic Encephalopathy; Hepatitis; Jaundice; Jaundice, Obstructive; Leucine; Liver Cirrhosis; Liver Diseases; Lysine; Research; Valine | 1964 |
ANTIDOTAL EFFECT OF AMINOACETONITRILE AGAINST THE BIOCHEMICAL INJURY OF THE MICROSOMAL AMINO-ACID INCORPORATING SYSTEM INDUCED IN VIVO BY CARBON TETRACHLORIDE OR DIMETHYLNITROSAMINE.
Topics: Amino Acids; Aminoacetonitrile; Antidotes; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cyanides; Dimethylnitrosamine; Hepatitis; Leucine; Liver; Microsomes; Nitrosamines; Pharmacology; Rats; Research; Toxicology | 1965 |
EFFECT OF THIOACETAMIDE-INDUCED SUBLETHAL HEPATIC CELL INJURY ON PROTEIN SYNTHESIS.
Topics: Amides; Carbon Isotopes; Chemical and Drug Induced Liver Injury; Electrons; Hepatitis; Hepatocytes; Leucine; Liver; Microscopy; Microscopy, Electron; Pharmacology; Proteins; Rats; Research; Ribosomes; RNA; Serum Albumin; Sulfhydryl Compounds; Thioacetamide; Toxicology | 1965 |
Biochemical changes in rat liver after acute beryllium poisoning.
Topics: Acid Phosphatase; Animals; Berylliosis; Blood Glucose; Calcium; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; DNA; Glucose; Isocitrate Dehydrogenase; Leucine; Lipids; Liver; Liver Glycogen; Lysosomes; Male; Microsomes; Mitochondria; Nitrosamines; Organ Size; Oxygen Consumption; Phosphoglucomutase; Proteins; Rats | 1967 |
The action of aflatoxin B1 on the rat liver.
Topics: Aflatoxins; Animals; Carbon Isotopes; Chemical and Drug Induced Liver Injury; DNA; Glutamate Dehydrogenase; In Vitro Techniques; Isocitrate Dehydrogenase; Leucine; Liver; Malate Dehydrogenase; Male; Necrosis; Orotic Acid; Phosphates; Phospholipids; Protein Biosynthesis; Rats; RNA | 1967 |
Impairments of RNA synthesis in Ehrlich ascites tumour by luteoskyrin, a hepatotoxic pigment of Penicillium islandicum Sopp.
Topics: Animals; Anthraquinones; Antimetabolites; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cell Nucleus; Chemical and Drug Induced Liver Injury; DNA, Neoplasm; Glycolysis; Lactates; Leucine; Male; Mice; Penicillium; Pigments, Biological; RNA, Neoplasm; Thymidine; Uracil | 1967 |
Ferritin synthesis in inflammation. II. Mechanism of increased ferritin synthesis.
Topics: Albumins; Animals; Apoferritins; Chemical and Drug Induced Liver Injury; Ferritins; Hemopexin; Hepatitis, Animal; Leucine; Liver; Male; Rats; Rats, Inbred Strains; Time Factors; Turpentine | 1981 |
Decreased incorporation of 14C-leucine in different liver nuclear protein fractions at early stages of carbon tetrachloride poisoning in the rat.
Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cycloheximide; Histones; Leucine; Liver; Male; Microsomes, Liver; Nuclear Proteins; Rats; Rats, Sprague-Dawley | 1994 |
Plasma alpha-amino-n-butyric acid to leucine ratio: nonspecificity as a marker for alcoholism.
Topics: Alcoholism; Aminobutyrates; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chronic Disease; Female; Hepatitis, Viral, Animal; Humans; Leucine; Liver Cirrhosis, Alcoholic; Male; Mice; Rats | 1978 |
Protective effect of S-adenosyl-L-methionine against CCl4-induced hepatotoxicity in cultured hepatocytes.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Cells, Cultured; Chemical and Drug Induced Liver Injury; Leucine; Male; Methionine; Rats; Rats, Inbred Strains; S-Adenosylmethionine | 1990 |
An epoxysuccinic acid derivative(loxistatin)-induced hepatic injury in rats and hamsters.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cricetinae; Cysteamine; Cysteine Proteinase Inhibitors; Drug Interactions; Glutathione; In Vitro Techniques; Leucine; Liver Diseases; Male; Maleates; Mesocricetus; Necrosis; Protein Binding; Rats; Rats, Inbred Strains; Species Specificity; Tissue Distribution | 1990 |
Further studies on the mechanism of the late protective effects of phenylmethylsulfonyl fluoride on carbon tetrachloride-induced liver necrosis.
Topics: Administration, Oral; Animals; Body Temperature; Calcium; Carbon Radioisotopes; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Glucose-6-Phosphatase; Glutathione; Leucine; Lipid Peroxidation; Lipids; Liver; Male; Microscopy, Electron; Microsomes, Liver; Necrosis; Phenylmethylsulfonyl Fluoride; Phosphorus Radioisotopes; Rats; Rats, Inbred Strains; Sulfones; Time Factors | 1989 |
Effects of valine on 15N incorporation into serum and tissue protein and non-protein fractions following 15N-L-leucine administration to normal and liver-injured rats.
Topics: Amino Acids; Animals; Brain; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Female; Leucine; Liver; Liver Diseases; Muscle Proteins; Muscles; Nitrogen; Nitrogen Isotopes; Protein Biosynthesis; Rats; Rats, Inbred Strains; Serum Albumin; Urea; Valine | 1989 |
Metabolism of branched-chain amino acids in rats with acute hepatic failure: a tracer study using 15N-leucine.
Topics: Alanine; Amino Acids, Branched-Chain; Animals; Chemical and Drug Induced Liver Injury; Galactosamine; Glucagon; Glutamine; Insulin; Isoleucine; Leucine; Liver Diseases; Male; Rats; Rats, Inbred Strains; Valine | 1985 |
The effect of acute liver damage on circulating ferritin levels in vivo and in the isolated perfused rat liver.
Topics: Animals; Chemical and Drug Induced Liver Injury; Ferritins; Galactosamine; In Vitro Techniques; Leucine; Liver; Liver Diseases; Male; Phagocytosis; Protein Biosynthesis; Rats; Rats, Inbred Strains | 1985 |
Changes in the rates of synthesis of certain plasma proteins following tissue damage due to talc injection. A study using the perfused rat liver.
Topics: Adrenal Glands; Alpha-Globulins; Animals; Blood; Blood Proteins; Carbon Isotopes; Chemical and Drug Induced Liver Injury; Chemical Precipitation; Chromatography; Electrophoresis; Fibrinogen; Immune Sera; Leucine; Liver; Liver Diseases; Mucoproteins; Perfusion; Rats; Talc; Time Factors | 1968 |
Studies on poisoning by Macrozamia communis. I. Biochemical disturbances in the liver.
Topics: Animals; Carbon Isotopes; Centrifugation, Density Gradient; Chemical and Drug Induced Liver Injury; Depression, Chemical; Female; Glycerophosphates; Leucine; Lipid Metabolism; Lipids; Liver; Lysosomes; Mitochondria, Liver; Phosphoric Monoester Hydrolases; Plant Poisoning; Polynucleotides; Protein Biosynthesis; Proteins; Rats; Ribosomes; Seeds; Stimulation, Chemical; Time Factors; Uracil Nucleotides | 1969 |
Studies on poisoning by Macrozamia communis. II. Effects of modifying agents upon changes induced in the liver by Macrozamia communis.
Topics: Adenosine Triphosphate; Aniline Compounds; Animals; Antioxidants; Body Temperature; Chemical and Drug Induced Liver Injury; Glucuronidase; Glutamates; Leucine; Lipid Metabolism; Liver; Malates; Mitochondria, Liver; Nucleosides; Phosphoric Monoester Hydrolases; Plant Poisoning; Promethazine; Protein Biosynthesis; Rats; Seeds; Succinates; Sulfhydryl Compounds; Temperature; Thermography | 1969 |
Sulfaguanidine protection of mouse liver from carbon tetrachloride-induced necrosis.
Topics: Aniline Compounds; Animals; Autoradiography; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Endoplasmic Reticulum; Glucose-6-Phosphatase; Guanidines; Histocytochemistry; Leucine; Liver; Liver Diseases; Male; Mice; Microscopy, Electron; Necrosis; Sulfaguanidine; Sulfonamides; Tritium | 1973 |
Talc injury: changes in glucosamine and leucine incorporation into liver and plasma proteins.
Topics: Animals; Blood Proteins; Carbon Radioisotopes; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Glucosamine; Glycoproteins; Granuloma; Injections, Subcutaneous; Leucine; Liver; Liver Diseases; Male; Mice; Mice, Inbred Strains; Perchlorates; Protein Biosynthesis; Solubility; Talc; Time Factors | 1973 |
[Ethanol-induced changes in protein synthesis of mitochondria and microsomes of rat brain and liver].
Topics: Alcoholic Intoxication; Animals; Brain; Chemical and Drug Induced Liver Injury; Chloramphenicol; Cycloheximide; Ethanol; Humans; Leucine; Liver; Microsomes; Microsomes, Liver; Mitochondria; Mitochondria, Liver; Protein Biosynthesis; Rats | 1973 |
Electron-microscopic and autoradiographic studies on the effect of halothane and chloroform on liver cells.
Topics: Anesthesia, Inhalation; Animals; Autoradiography; Blood Coagulation Factors; Blood Volume; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chloroform; Fatty Liver; Female; Fibrinogen; Halothane; Hepatitis A; Humans; Leucine; Liver; Liver Circulation; Microscopy, Electron; Microsomes; Oxygen; Protein Biosynthesis; Prothrombin; Rats; Ribosomes; RNA; Time Factors | 1968 |
Transfer RNA patterns in livers of rats fed diets containing 3'-methyl-4-dimethylaminoazobenzene.
Topics: Amino Acids; Animals; Arginine; Carbon Isotopes; Cell Transformation, Neoplastic; Chemical and Drug Induced Liver Injury; Chromatography; Female; Histidine; Leucine; Liver Diseases; Lysine; Methionine; Methylation; p-Dimethylaminoazobenzene; Phenylalanine; Precancerous Conditions; Rats; RNA, Transfer; Serine; Threonine; Tritium; Tyrosine; Valine | 1970 |
Dynamics of liver cell injury and repair. I. Spontaneous reformation of the nucleolus and polyribosomes in the presence of extensive cytoplasmic damage induced by ethionine.
Topics: Adenosine Triphosphate; Animals; Carbon Isotopes; Cell Nucleolus; Chemical and Drug Induced Liver Injury; Cytoplasm; Endoplasmic Reticulum; Ethionine; Fatty Liver; Female; Leucine; Lipid Metabolism; Liver; Microscopy, Electron; Nucleoproteins; Rats; Ribosomes; RNA; Time Factors | 1970 |
Effect of CCl4 intoxication on the synthesis of beta-lipoprotein fractions in rat liver.
Topics: Animals; Carbon Isotopes; Carbon Tetrachloride Poisoning; Centrifugation, Density Gradient; Chemical and Drug Induced Liver Injury; Chemical Precipitation; Leucine; Lipoproteins; Liver; Male; Palmitic Acids; Rats; Tritium | 1968 |
Effects of the hepatotoxic agents retrorsine and aflatoxin B1 on hepatic protein synthesis in the rat.
Topics: Aflatoxins; Alkaloids; Animals; Blood Proteins; Carbon Isotopes; Cell Nucleus; Cell-Free System; Chemical and Drug Induced Liver Injury; Depression, Chemical; Heterocyclic Compounds; Leucine; Liver; Male; Orotic Acid; Protein Biosynthesis; Rats; Ribosomes; RNA | 1968 |
The effect of chronic carbon tetrachloride inhalation on the secretion of lipid by rat liver.
Topics: Animals; Aspartate Aminotransferases; Carbon Isotopes; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Leucine; Lipid Metabolism; Liver; Liver Glycogen; Male; Palmitic Acids; Rats; Triglycerides; Tritium | 1968 |
Changes associated with the production of fatty livers by white phosphorus and by ethanol in the rat.
Topics: Acetates; Animals; Chemical and Drug Induced Liver Injury; Cholesterol; Ethanol; Fatty Liver; Leucine; Lipoproteins; Phosphates; Phospholipids; Phosphorus; Rats | 1964 |