leucine and Chemical and Drug Induced Liver Injury

leucine has been researched along with Chemical and Drug Induced Liver Injury in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199027 (81.82)18.7374
1990's3 (9.09)18.2507
2000's0 (0.00)29.6817
2010's3 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Calado, RT; Clé, DV1
Agundez, JA; Andrade, RJ; Borraz, Y; Castiella, A; De Dios, AM; Durán, JA; Fernandez, MC; García-Martín, E; Guarner, C; Lucena, MI; Martínez, C; Planas, R; Romero-Gomez, M; Ruiz, JD; Soriano, G; Stephens, C; Ulzurrun, E1
AFZELIUS, BA; ARRHENIUS, E; GUSTAFSSON, RG; MUKHERJEE, T1
ANAGNOSTOU, E; HADZIYANNIS, S; KAKARI, S; MERICAS, G1
MONDEN, M1
BORNSTEIN, S; HALBREICH, A; MAGER, J1
ASHWORTH, CT; WERNER, JD; WRIGHTSMAN, FJ1
Alldridge, WN; Witschi, HP1
Clifford, JI; Rees, KR1
Ito, K; Tatsuno, T; Ueno, I; Ueno, Y1
Carmel, N; Hershko, C; Konijn, AM; Levy, R1
Castro, JA; Díaz Gómez, MI; Galelli, M1
Carter, EA; Dienstag, JL; Fischer, JE; Isselbacher, KJ; Wands, JR1
Kodama, K; Oguchi, K; Tsuji, M1
Arai, M; Fukushima, K; Kohno, Y; Satoh, T; Suwa, T1
Bernacchi, AS; Castro, JA; de Castro, CR; de Fenos, OM; de Ferreyra, EC; Fernández, G; Villarruel, MC1
Okita, M; Tsuji, T; Watanabe, A1
Nagashima, H; Ukida, M; Usui, H1
Cooksley, WG; Halliday, JW; Mack, U; Owens, J; Powell, LW1
Gordon, AH; Koj, A1
Healy, PJ2
Leduc, LH1
Bolmey, S; Kaltenbach, JP1
Bertolino, A; Giovine, A; Renis, M; Rizzi, MM1
Scholler, KL1
Goldman, M; Griffin, AC1
Farber, E; Liang, H; Reid, IM; Shinozuka, H; Shull, KH1
Albano, O; Francavilla, A1
Leaver, DD; Villa-Treviño, S1
Kanics, L; Rubinstein, D1
Robinson, DS; Seakins, A1

Reviews

1 review(s) available for leucine and Chemical and Drug Induced Liver Injury

ArticleYear
Treatment of inherited bone marrow failure syndromes beyond transplantation.
    Hematology. American Society of Hematology. Education Program, 2017, 12-08, Volume: 2017, Issue:1

    Topics: Androgens; Bone Marrow Diseases; Chemical and Drug Induced Liver Injury; Danazol; Female; Genetic Diseases, Inborn; Genetic Therapy; Humans; Leucine; Oxymetholone; Quercetin; Stem Cell Transplantation; Syndrome; Virilism

2017

Other Studies

32 other study(ies) available for leucine and Chemical and Drug Induced Liver Injury

ArticleYear
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitochondrial superoxide dismutase and glutathione peroxidase in idiosyncratic drug-induced liver injury.
    Hepatology (Baltimore, Md.), 2010, Volume: 52, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alleles; Amino Acid Substitution; Chemical and Drug Induced Liver Injury; Female; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; Leucine; Male; Middle Aged; Mitochondria; Polymorphism, Genetic; Superoxide Dismutase; Young Adult

2010
EFFECTS OF CARCINOGENIC AMINES ON AMINO ACID INCORPORATION BY LIVER SYSTEMS. II. A MORPHOLOGICAL AND BIOCHEMICAL STUDY ON THE EFFECT OF DIMETHYLNITROSAMINE.
    Cancer research, 1963, Volume: 23

    Topics: Amines; Amino Acids; Carbon Isotopes; Carcinogens; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Electrons; Hepatitis; Leucine; Liver; Liver Glycogen; Liver Neoplasms; Microscopy; Microscopy, Electron; Mitochondria; Nitrosamines; Proteins; Rats; Research; Toxicology

1963
THE DIAGNOSTIC VALUE OF SERUM LEUCINE AMINOPEPTIDASE.
    Journal of clinical pathology, 1964, Volume: 17

    Topics: Adolescent; Aminopeptidases; Chemical and Drug Induced Liver Injury; Child; Cholecystitis; Cholelithiasis; Clinical Enzyme Tests; Gallstones; Geriatrics; Hepatitis; Hepatitis A; Jaundice; Jaundice, Obstructive; Leucine; Leucyl Aminopeptidase; Liver Neoplasms; Neoplasm Metastasis; Pancreatic Neoplasms

1964
[A STUDY OF THE FREE AMINO ACIDS IN THE SERUM OF LIVER DISEASES].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1964, May-10, Volume: 53

    Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Blood; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Dogs; Glutamates; Glycine; Hepatic Encephalopathy; Hepatitis; Jaundice; Jaundice, Obstructive; Leucine; Liver Cirrhosis; Liver Diseases; Lysine; Research; Valine

1964
ANTIDOTAL EFFECT OF AMINOACETONITRILE AGAINST THE BIOCHEMICAL INJURY OF THE MICROSOMAL AMINO-ACID INCORPORATING SYSTEM INDUCED IN VIVO BY CARBON TETRACHLORIDE OR DIMETHYLNITROSAMINE.
    Biochemical and biophysical research communications, 1965, Feb-17, Volume: 18

    Topics: Amino Acids; Aminoacetonitrile; Antidotes; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cyanides; Dimethylnitrosamine; Hepatitis; Leucine; Liver; Microsomes; Nitrosamines; Pharmacology; Rats; Research; Toxicology

1965
EFFECT OF THIOACETAMIDE-INDUCED SUBLETHAL HEPATIC CELL INJURY ON PROTEIN SYNTHESIS.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1965, Volume: 119

    Topics: Amides; Carbon Isotopes; Chemical and Drug Induced Liver Injury; Electrons; Hepatitis; Hepatocytes; Leucine; Liver; Microscopy; Microscopy, Electron; Pharmacology; Proteins; Rats; Research; Ribosomes; RNA; Serum Albumin; Sulfhydryl Compounds; Thioacetamide; Toxicology

1965
Biochemical changes in rat liver after acute beryllium poisoning.
    Biochemical pharmacology, 1967, Volume: 16, Issue:2

    Topics: Acid Phosphatase; Animals; Berylliosis; Blood Glucose; Calcium; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; DNA; Glucose; Isocitrate Dehydrogenase; Leucine; Lipids; Liver; Liver Glycogen; Lysosomes; Male; Microsomes; Mitochondria; Nitrosamines; Organ Size; Oxygen Consumption; Phosphoglucomutase; Proteins; Rats

1967
The action of aflatoxin B1 on the rat liver.
    The Biochemical journal, 1967, Volume: 102, Issue:1

    Topics: Aflatoxins; Animals; Carbon Isotopes; Chemical and Drug Induced Liver Injury; DNA; Glutamate Dehydrogenase; In Vitro Techniques; Isocitrate Dehydrogenase; Leucine; Liver; Malate Dehydrogenase; Male; Necrosis; Orotic Acid; Phosphates; Phospholipids; Protein Biosynthesis; Rats; RNA

1967
Impairments of RNA synthesis in Ehrlich ascites tumour by luteoskyrin, a hepatotoxic pigment of Penicillium islandicum Sopp.
    Experientia, 1967, Dec-15, Volume: 23, Issue:12

    Topics: Animals; Anthraquinones; Antimetabolites; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cell Nucleus; Chemical and Drug Induced Liver Injury; DNA, Neoplasm; Glycolysis; Lactates; Leucine; Male; Mice; Penicillium; Pigments, Biological; RNA, Neoplasm; Thymidine; Uracil

1967
Ferritin synthesis in inflammation. II. Mechanism of increased ferritin synthesis.
    British journal of haematology, 1981, Volume: 49, Issue:3

    Topics: Albumins; Animals; Apoferritins; Chemical and Drug Induced Liver Injury; Ferritins; Hemopexin; Hepatitis, Animal; Leucine; Liver; Male; Rats; Rats, Inbred Strains; Time Factors; Turpentine

1981
Decreased incorporation of 14C-leucine in different liver nuclear protein fractions at early stages of carbon tetrachloride poisoning in the rat.
    Archives of toxicology, 1994, Volume: 68, Issue:3

    Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cycloheximide; Histones; Leucine; Liver; Male; Microsomes, Liver; Nuclear Proteins; Rats; Rats, Sprague-Dawley

1994
Plasma alpha-amino-n-butyric acid to leucine ratio: nonspecificity as a marker for alcoholism.
    Gastroenterology, 1978, Volume: 75, Issue:4

    Topics: Alcoholism; Aminobutyrates; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chronic Disease; Female; Hepatitis, Viral, Animal; Humans; Leucine; Liver Cirrhosis, Alcoholic; Male; Mice; Rats

1978
Protective effect of S-adenosyl-L-methionine against CCl4-induced hepatotoxicity in cultured hepatocytes.
    Japanese journal of pharmacology, 1990, Volume: 52, Issue:2

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Cells, Cultured; Chemical and Drug Induced Liver Injury; Leucine; Male; Methionine; Rats; Rats, Inbred Strains; S-Adenosylmethionine

1990
An epoxysuccinic acid derivative(loxistatin)-induced hepatic injury in rats and hamsters.
    Toxicology and applied pharmacology, 1990, Volume: 105, Issue:1

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cricetinae; Cysteamine; Cysteine Proteinase Inhibitors; Drug Interactions; Glutathione; In Vitro Techniques; Leucine; Liver Diseases; Male; Maleates; Mesocricetus; Necrosis; Protein Binding; Rats; Rats, Inbred Strains; Species Specificity; Tissue Distribution

1990
Further studies on the mechanism of the late protective effects of phenylmethylsulfonyl fluoride on carbon tetrachloride-induced liver necrosis.
    Experimental and molecular pathology, 1989, Volume: 50, Issue:2

    Topics: Administration, Oral; Animals; Body Temperature; Calcium; Carbon Radioisotopes; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Glucose-6-Phosphatase; Glutathione; Leucine; Lipid Peroxidation; Lipids; Liver; Male; Microscopy, Electron; Microsomes, Liver; Necrosis; Phenylmethylsulfonyl Fluoride; Phosphorus Radioisotopes; Rats; Rats, Inbred Strains; Sulfones; Time Factors

1989
Effects of valine on 15N incorporation into serum and tissue protein and non-protein fractions following 15N-L-leucine administration to normal and liver-injured rats.
    Journal of nutritional science and vitaminology, 1989, Volume: 35, Issue:6

    Topics: Amino Acids; Animals; Brain; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Female; Leucine; Liver; Liver Diseases; Muscle Proteins; Muscles; Nitrogen; Nitrogen Isotopes; Protein Biosynthesis; Rats; Rats, Inbred Strains; Serum Albumin; Urea; Valine

1989
Metabolism of branched-chain amino acids in rats with acute hepatic failure: a tracer study using 15N-leucine.
    Acta medica Okayama, 1985, Volume: 39, Issue:5

    Topics: Alanine; Amino Acids, Branched-Chain; Animals; Chemical and Drug Induced Liver Injury; Galactosamine; Glucagon; Glutamine; Insulin; Isoleucine; Leucine; Liver Diseases; Male; Rats; Rats, Inbred Strains; Valine

1985
The effect of acute liver damage on circulating ferritin levels in vivo and in the isolated perfused rat liver.
    British journal of experimental pathology, 1985, Volume: 66, Issue:2

    Topics: Animals; Chemical and Drug Induced Liver Injury; Ferritins; Galactosamine; In Vitro Techniques; Leucine; Liver; Liver Diseases; Male; Phagocytosis; Protein Biosynthesis; Rats; Rats, Inbred Strains

1985
Changes in the rates of synthesis of certain plasma proteins following tissue damage due to talc injection. A study using the perfused rat liver.
    British journal of experimental pathology, 1968, Volume: 49, Issue:5

    Topics: Adrenal Glands; Alpha-Globulins; Animals; Blood; Blood Proteins; Carbon Isotopes; Chemical and Drug Induced Liver Injury; Chemical Precipitation; Chromatography; Electrophoresis; Fibrinogen; Immune Sera; Leucine; Liver; Liver Diseases; Mucoproteins; Perfusion; Rats; Talc; Time Factors

1968
Studies on poisoning by Macrozamia communis. I. Biochemical disturbances in the liver.
    Biochemical pharmacology, 1969, Volume: 18, Issue:1

    Topics: Animals; Carbon Isotopes; Centrifugation, Density Gradient; Chemical and Drug Induced Liver Injury; Depression, Chemical; Female; Glycerophosphates; Leucine; Lipid Metabolism; Lipids; Liver; Lysosomes; Mitochondria, Liver; Phosphoric Monoester Hydrolases; Plant Poisoning; Polynucleotides; Protein Biosynthesis; Proteins; Rats; Ribosomes; Seeds; Stimulation, Chemical; Time Factors; Uracil Nucleotides

1969
Studies on poisoning by Macrozamia communis. II. Effects of modifying agents upon changes induced in the liver by Macrozamia communis.
    Biochemical pharmacology, 1969, Volume: 18, Issue:1

    Topics: Adenosine Triphosphate; Aniline Compounds; Animals; Antioxidants; Body Temperature; Chemical and Drug Induced Liver Injury; Glucuronidase; Glutamates; Leucine; Lipid Metabolism; Liver; Malates; Mitochondria, Liver; Nucleosides; Phosphoric Monoester Hydrolases; Plant Poisoning; Promethazine; Protein Biosynthesis; Rats; Seeds; Succinates; Sulfhydryl Compounds; Temperature; Thermography

1969
Sulfaguanidine protection of mouse liver from carbon tetrachloride-induced necrosis.
    Laboratory investigation; a journal of technical methods and pathology, 1973, Volume: 29, Issue:2

    Topics: Aniline Compounds; Animals; Autoradiography; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Endoplasmic Reticulum; Glucose-6-Phosphatase; Guanidines; Histocytochemistry; Leucine; Liver; Liver Diseases; Male; Mice; Microscopy, Electron; Necrosis; Sulfaguanidine; Sulfonamides; Tritium

1973
Talc injury: changes in glucosamine and leucine incorporation into liver and plasma proteins.
    Experimental and molecular pathology, 1973, Volume: 19, Issue:3

    Topics: Animals; Blood Proteins; Carbon Radioisotopes; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Glucosamine; Glycoproteins; Granuloma; Injections, Subcutaneous; Leucine; Liver; Liver Diseases; Male; Mice; Mice, Inbred Strains; Perchlorates; Protein Biosynthesis; Solubility; Talc; Time Factors

1973
[Ethanol-induced changes in protein synthesis of mitochondria and microsomes of rat brain and liver].
    Bollettino della Societa italiana di biologia sperimentale, 1973, Sep-15, Volume: 49, Issue:17

    Topics: Alcoholic Intoxication; Animals; Brain; Chemical and Drug Induced Liver Injury; Chloramphenicol; Cycloheximide; Ethanol; Humans; Leucine; Liver; Microsomes; Microsomes, Liver; Mitochondria; Mitochondria, Liver; Protein Biosynthesis; Rats

1973
Electron-microscopic and autoradiographic studies on the effect of halothane and chloroform on liver cells.
    Acta anaesthesiologica Scandinavica. Supplementum, 1968, Volume: 32

    Topics: Anesthesia, Inhalation; Animals; Autoradiography; Blood Coagulation Factors; Blood Volume; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chloroform; Fatty Liver; Female; Fibrinogen; Halothane; Hepatitis A; Humans; Leucine; Liver; Liver Circulation; Microscopy, Electron; Microsomes; Oxygen; Protein Biosynthesis; Prothrombin; Rats; Ribosomes; RNA; Time Factors

1968
Transfer RNA patterns in livers of rats fed diets containing 3'-methyl-4-dimethylaminoazobenzene.
    Cancer research, 1970, Volume: 30, Issue:6

    Topics: Amino Acids; Animals; Arginine; Carbon Isotopes; Cell Transformation, Neoplastic; Chemical and Drug Induced Liver Injury; Chromatography; Female; Histidine; Leucine; Liver Diseases; Lysine; Methionine; Methylation; p-Dimethylaminoazobenzene; Phenylalanine; Precancerous Conditions; Rats; RNA, Transfer; Serine; Threonine; Tritium; Tyrosine; Valine

1970
Dynamics of liver cell injury and repair. I. Spontaneous reformation of the nucleolus and polyribosomes in the presence of extensive cytoplasmic damage induced by ethionine.
    Laboratory investigation; a journal of technical methods and pathology, 1970, Volume: 23, Issue:3

    Topics: Adenosine Triphosphate; Animals; Carbon Isotopes; Cell Nucleolus; Chemical and Drug Induced Liver Injury; Cytoplasm; Endoplasmic Reticulum; Ethionine; Fatty Liver; Female; Leucine; Lipid Metabolism; Liver; Microscopy, Electron; Nucleoproteins; Rats; Ribosomes; RNA; Time Factors

1970
Effect of CCl4 intoxication on the synthesis of beta-lipoprotein fractions in rat liver.
    Clinica chimica acta; international journal of clinical chemistry, 1968, Volume: 19, Issue:3

    Topics: Animals; Carbon Isotopes; Carbon Tetrachloride Poisoning; Centrifugation, Density Gradient; Chemical and Drug Induced Liver Injury; Chemical Precipitation; Leucine; Lipoproteins; Liver; Male; Palmitic Acids; Rats; Tritium

1968
Effects of the hepatotoxic agents retrorsine and aflatoxin B1 on hepatic protein synthesis in the rat.
    The Biochemical journal, 1968, Volume: 109, Issue:1

    Topics: Aflatoxins; Alkaloids; Animals; Blood Proteins; Carbon Isotopes; Cell Nucleus; Cell-Free System; Chemical and Drug Induced Liver Injury; Depression, Chemical; Heterocyclic Compounds; Leucine; Liver; Male; Orotic Acid; Protein Biosynthesis; Rats; Ribosomes; RNA

1968
The effect of chronic carbon tetrachloride inhalation on the secretion of lipid by rat liver.
    Biochemical pharmacology, 1968, Volume: 17, Issue:9

    Topics: Animals; Aspartate Aminotransferases; Carbon Isotopes; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Leucine; Lipid Metabolism; Liver; Liver Glycogen; Male; Palmitic Acids; Rats; Triglycerides; Tritium

1968
Changes associated with the production of fatty livers by white phosphorus and by ethanol in the rat.
    The Biochemical journal, 1964, Volume: 92, Issue:2

    Topics: Acetates; Animals; Chemical and Drug Induced Liver Injury; Cholesterol; Ethanol; Fatty Liver; Leucine; Lipoproteins; Phosphates; Phospholipids; Phosphorus; Rats

1964