leucine and Cataract

leucine has been researched along with Cataract in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199013 (43.33)18.7374
1990's11 (36.67)18.2507
2000's5 (16.67)29.6817
2010's1 (3.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dong, Y; Xiao, J; Zhao, M; Zheng, Y; Zhu, C1
CATALINO, P; TITTARELLI, R1
DEVI, A; RAINA, PL; SINGH, A1
Eiberg, H; Funding, M; Hansen, L; Hejtmancik, JF; Kjaer, KW; Riise, R; Rosenberg, T; Yao, W1
Hennies, HC; Nürnberg, P; Singh, D; Singh, JR; Sperling, K; Vanita, V1
Guleria, K; Singh, D; Singh, JR; Sperling, K; Vanita, V; Varon, R1
Bhatnagar, R; Chauhan, BS; Desai, NC; Garg, SP1
Kuck, JF1
Kuck, JF; Kuck, KD1
David, LL; Iwasaki, N; Shearer, TR1
Asano, G; Shimizu, Y; Win, T1
Azuma, M; David, LL; Kadoya, K; Shearer, TR1
Dean, RT; Fu, SL1
Azuma, M; Fukiage, C; Nakamura, Y; Shearer, TR1
Baruch, A; Bogyo, M; Gilula, NB; Greenbaum, D; Kumar, NM; Levy, ET; Nielsen, PA1
Bhatnagar, A; Chandra, D; Christensen, BN; Ramana, KV; Srivastava, SK; Wang, L1
Cenedella, RJ1
Fukui, HN; Kinoshita, JH; Obazawa, H1
Azuma, M; David, LL; Kadoya, K; Lampi, KJ; Shearer, TR1
Azuma, M; David, LL; Shearer, TR3
Azuma, M; David, LL; Murachi, T; Shearer, TR1
Courtois, Y; Galera, P; Haloui, Z; Laurent, M; Pujol, JP1
Benedek, GB; Hocker, LO; Jedziniak, JA; Kinoshita, JH; Yates, EM1
Gruber, L; Harris, JE1
Hanna, C; McDonald, JE; Roy, FH1
Carta, F; Maraini, G; Pescatori, A; Prosperi, L1
Graeber, W1
Koyama, T1

Other Studies

30 other study(ies) available for leucine and Cataract

ArticleYear
MicroRNA let-7b induces lens epithelial cell apoptosis by targeting leucine-rich repeat containing G protein-coupled receptor 4 (Lgr4) in age-related cataract.
    Experimental eye research, 2016, Volume: 147

    Topics: Aged; Apoptosis; Cataract; Cell Line; Down-Regulation; Epithelial Cells; Female; Humans; Lens, Crystalline; Leucine; Male; MicroRNAs; Middle Aged; Receptors, G-Protein-Coupled; Ultraviolet Rays; Up-Regulation

2016
[Contribution to the study of experimental cataract induced by leucinol (leucine, momosine)].
    Bollettino d'oculistica, 1961, Volume: 40

    Topics: Alanine; Cataract; Leucine; Pyridines

1961
ABNORMAL PROTEIN AND NUCLEIC ACID METABOLISM AS A CAUSE OF CATARACT FORMATION INDUCED BY NUTRITIONAL DEFICIENCY IN RABBITS.
    The British journal of ophthalmology, 1965, Volume: 49

    Topics: Animals; Carbon Isotopes; Cataract; DNA; Eye Proteins; Histocytochemistry; Lens, Crystalline; Leucine; Malnutrition; Metabolism; Muscular Dystrophies; Nucleosides; Proteins; Rabbits; Radiometry; Research; RNA; Thymidine; Uridine; Vitamin E Deficiency

1965
The congenital "ant-egg" cataract phenotype is caused by a missense mutation in connexin46.
    Molecular vision, 2006, Sep-01, Volume: 12

    Topics: Amino Acid Sequence; Base Sequence; Cataract; Connexins; Female; Haplotypes; Humans; Leucine; Lod Score; Male; Molecular Sequence Data; Mutation, Missense; Pedigree; Phenotype; Protein Sorting Signals; Protein Structure, Tertiary; Serine

2006
A novel mutation in GJA8 associated with autosomal dominant congenital cataract in a family of Indian origin.
    Molecular vision, 2006, Oct-18, Volume: 12

    Topics: Asian People; Base Sequence; Cataract; Child; Connexins; Cytosine; DNA Mutational Analysis; Eye Proteins; Female; Genes, Dominant; Genetic Linkage; Genotype; Guanine; Haplotypes; Heterozygote; Humans; India; Leucine; Male; Molecular Sequence Data; Mutation; Phenotype; Protein Structure, Tertiary; Transcription Initiation Site; Valine

2006
A novel mutation in the connexin 46 (GJA3) gene associated with autosomal dominant congenital cataract in an Indian family.
    Molecular vision, 2007, Sep-11, Volume: 13

    Topics: Amino Acid Substitution; Arginine; Asian People; Cataract; Chromosome Mapping; Chromosomes, Human, Pair 13; Connexins; DNA Mutational Analysis; Female; Genes, Dominant; Genetic Linkage; Guanine; Haplotypes; Heterozygote; Humans; India; Leucine; Lod Score; Male; Mutation; Oligonucleotide Array Sequence Analysis; Pedigree; Polymorphism, Single Nucleotide; Thymine

2007
Study of the relationship between free amino acids and cataract in human lenses.
    Experimental eye research, 1984, Volume: 38, Issue:2

    Topics: Adult; Aged; Alanine; Amino Acids; Cataract; Glutamates; Glutamic Acid; Glycine; Humans; Lens, Crystalline; Leucine; Middle Aged; Serine; Threonine

1984
Effect of long-wave ultraviolet light on the lens. IV. Leucine metabolism in normal human lenses in vitro.
    Ophthalmic research, 1983, Volume: 15, Issue:4

    Topics: Adult; Aged; Cataract; Crystallins; Humans; In Vitro Techniques; Lens, Crystalline; Leucine; Middle Aged; Ultraviolet Rays

1983
The Emory mouse cataract: accumulation of free leucine and incorporation into protein by cataractous and clear lenses.
    Current eye research, 1984, Volume: 3, Issue:3

    Topics: Age Factors; Animals; Cataract; Crystallins; Energy Metabolism; Lens, Crystalline; Leucine; Mice; Mice, Inbred Strains

1984
Crystallin degradation and insolubilization in regions of young rat lens with calcium ionophore cataract.
    Investigative ophthalmology & visual science, 1995, Volume: 36, Issue:2

    Topics: Aging; Amino Acid Sequence; Animals; Calcimycin; Calpain; Cataract; Crystallins; Cysteine Proteinase Inhibitors; Lens, Crystalline; Leucine; Molecular Sequence Data; Organ Culture Techniques; Protein Denaturation; Rats; Rats, Sprague-Dawley; Solubility

1995
The efficacy of aldose reductase inhibitor, antioxidant butylated hydroxytoluene and cysteine protease inhibitor E64 on hyperglycemia-induced metabolic changes in the organ-cultured bovine lens.
    Nihon Ika Daigaku zasshi, 1994, Volume: 61, Issue:3

    Topics: Aldehyde Reductase; Animals; Butylated Hydroxytoluene; Cataract; Cattle; Culture Techniques; Cysteine Proteinase Inhibitors; Hyperglycemia; Lens, Crystalline; Leucine; Magnetic Resonance Spectroscopy

1994
Role of calpain in hydrogen peroxide induced cataract.
    Current eye research, 1993, Volume: 12, Issue:4

    Topics: Animals; Calcium; Calpain; Cataract; Crystallins; Cysteine Proteinase Inhibitors; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Hydrogen Peroxide; Lens, Crystalline; Leucine; Organ Culture Techniques; Rats; Rats, Sprague-Dawley

1993
Structural characterization of the products of hydroxyl-radical damage to leucine and their detection on proteins.
    The Biochemical journal, 1997, May-15, Volume: 324 ( Pt 1)

    Topics: Cataract; Chromatography, High Pressure Liquid; Crystallins; Humans; Hydroxyl Radical; Indicators and Reagents; Lens, Crystalline; Leucine; Lipoproteins; o-Phthalaldehyde; Oligopeptides; Oxidation-Reduction; Proline; Schiff Bases; Valine

1997
Oxidation enhances calpain-induced turbidity in young rat lenses.
    Current eye research, 1999, Volume: 19, Issue:1

    Topics: Animals; Antioxidants; Calpain; Cataract; Crystallins; Culture Techniques; Cysteine Proteinase Inhibitors; Diamide; Dithioerythritol; Drug Synergism; Glutathione; Lens, Crystalline; Leucine; Oxidants; Oxidation-Reduction; Peptide Hydrolases; Rats; Rats, Sprague-Dawley

1999
Defining a link between gap junction communication, proteolysis, and cataract formation.
    The Journal of biological chemistry, 2001, Aug-03, Volume: 276, Issue:31

    Topics: Animals; Calcium; Calpain; Cataract; Cell Communication; Connexins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Gap Junctions; Lens, Crystalline; Leucine; Mice; Mice, Inbred Strains; Mice, Knockout; Organ Culture Techniques

2001
Inhibition of fiber cell globulization and hyperglycemia-induced lens opacification by aminopeptidase inhibitor bestatin.
    Investigative ophthalmology & visual science, 2002, Volume: 43, Issue:7

    Topics: Aminopeptidases; Animals; Calcium; Calpain; Cataract; Chromatography, Ion Exchange; Glucose; Glutathione; Hyperglycemia; Lens Cortex, Crystalline; Leucine; Organ Culture Techniques; Phthalimides; Protease Inhibitors; Rats; Rats, Sprague-Dawley

2002
Composition and synthesis in vivo of water-soluble proteins in the rat ocular lens: normal and cataractous.
    Experimental eye research, 1979, Volume: 29, Issue:6

    Topics: Animals; Cataract; Crystallins; Electrophoresis, Polyacrylamide Gel; Lens, Crystalline; Leucine; Molecular Weight; Rats; Solubility

1979
Lens growth in the Nakano mouse.
    Investigative ophthalmology, 1976, Volume: 15, Issue:5

    Topics: Aging; Animals; Cataract; Crystallins; Lens, Crystalline; Leucine; Mice

1976
Comparison of cell-permeable calpain inhibitors and E64 in reduction of cataract in cultured rat lenses.
    Toxicology and applied pharmacology, 1992, Volume: 117, Issue:1

    Topics: Amino Acid Sequence; Animals; Calcimycin; Calpain; Cataract; Cell Membrane Permeability; Chromatography, High Pressure Liquid; Culture Techniques; Cysteine Proteinase Inhibitors; Dipeptides; Drug Interactions; Electrophoresis, Polyacrylamide Gel; Glycoproteins; Lens, Crystalline; Leucine; Leupeptins; Molecular Sequence Data; Rats; Rats, Sprague-Dawley

1992
Superior prevention of calcium ionophore cataract by E64d.
    Biochimica et biophysica acta, 1992, Dec-10, Volume: 1180, Issue:2

    Topics: Animals; Calcimycin; Calcium; Calpain; Cataract; Crystallins; Cysteine Proteinase Inhibitors; Lens, Crystalline; Leucine; Organ Culture Techniques; Organ Size; Rats; Rats, Sprague-Dawley

1992
Hydration and elevated calcium alone do not produce xylose nuclear cataract: role of proteolysis by calpain.
    Ophthalmic research, 1992, Volume: 24, Issue:1

    Topics: Animals; Calcium; Calpain; Cataract; Cysteine Proteinase Inhibitors; Lens, Crystalline; Leucine; Organ Culture Techniques; Rats; Rats, Inbred Strains; Xylose

1992
Amelioration of cataracts and proteolysis in cultured lenses by cysteine protease inhibitor E64.
    Investigative ophthalmology & visual science, 1991, Volume: 32, Issue:3

    Topics: Animals; Calcimycin; Calpain; Cataract; Chromatography, High Pressure Liquid; Crystallins; Culture Techniques; Cysteine Proteinase Inhibitors; Electrophoresis, Polyacrylamide Gel; Immunoblotting; Lens, Crystalline; Leucine; Rats; Rats, Inbred Strains; Selenium; Sodium Selenite; Xylose

1991
Cysteine protease inhibitor E64 reduces the rate of formation of selenite cataract in the whole animal.
    Current eye research, 1991, Volume: 10, Issue:7

    Topics: Animals; Body Water; Calcium; Calpain; Cataract; Crystallins; Cysteine Proteinase Inhibitors; Disease Models, Animal; Electrophoresis, Polyacrylamide Gel; Immunoblotting; Injections, Intraperitoneal; Lens, Crystalline; Leucine; Organ Culture Techniques; Rats; Rats, Inbred Strains; Selenious Acid; Selenium

1991
Analysis of lens protein synthesis in a cataractous mutant mouse: the Cat Fraser.
    Experimental eye research, 1990, Volume: 51, Issue:5

    Topics: Animals; Cataract; Collagen; Crystallins; Epithelium; Hydroxyproline; Lens Capsule, Crystalline; Lens, Crystalline; Leucine; Mice; Mice, Inbred Strains; Mice, Mutant Strains; Proline

1990
On the presence and mechanism of formation of heavy molecular weight aggregates in human normal and cataractous lenses.
    Experimental eye research, 1973, Volume: 15, Issue:2

    Topics: Adult; Age Factors; Aged; Amino Acids; Calcium; Cataract; Chromatography, DEAE-Cellulose; Chromatography, Gel; Crystallins; Humans; Leucine; Molecular Weight; Tyrosine

1973
The reversal of triparanol-induced cataracts in the rat. 3. Amino acid content and uptake of 14 C -AIB in cataractous and clearing lenses.
    Investigative ophthalmology, 1973, Volume: 12, Issue:5

    Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Arginine; Aspartic Acid; Carbon Isotopes; Cataract; Cystine; Diet; Glutamates; Glycine; Histidine; Isoleucine; Lens, Crystalline; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rats; Serine; Threonine; Triparanol; Tyrosine; Valine

1973
After-cataract of the rabbit: autoradiography and electron microscopy.
    Annals of ophthalmology, 1974, Volume: 6, Issue:1

    Topics: Animals; Autoradiography; Cataract; DNA; Epithelium; Lens, Crystalline; Leucine; Microscopy, Electron; Mitosis; Rabbits; Regeneration; Thymidine; Tritium; Wound Healing

1974
Protein metabolism in human senile cataract.
    Experimental eye research, 1971, Volume: 11, Issue:1

    Topics: Adenosine Triphosphate; Aged; Amino Acids; Animals; Arginine; Aspartic Acid; Biological Transport; Cataract; Crystallins; Guanosine Triphosphate; Humans; Lens, Crystalline; Leucine; Rabbits; Tritium

1971
[The amino acid composition of human lens proteins in the course of lens alterations and cataract transformation. I. The amino acid composition of unclouded human lenses of various age groups].
    Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1966, Dec-15, Volume: 171, Issue:3

    Topics: Adult; Age Factors; Aged; Aging; Alanine; Amino Acids; Arginine; Asparagine; Cataract; Crystallins; Glutamates; Glycine; Humans; Isoleucine; Lens, Crystalline; Leucine; Lysine; Middle Aged; Nitrogen; Peptide Hydrolases; Phenylalanine; Tyrosine

1966
[Protein synthesis in the lens and its disturbance. 2. Accumulation of 14C-L-leucine by x-irradiated and naphthalenefed rabbit lenses].
    Nippon Ganka Gakkai zasshi, 1970, Volume: 74, Issue:8

    Topics: Animals; Carbon Isotopes; Cataract; Crystallins; Lens, Crystalline; Leucine; Naphthalenes; Rabbits; Radiation Effects

1970