leucine and Cancer of Prostate

leucine has been researched along with Cancer of Prostate in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19902 (5.26)18.7374
1990's7 (18.42)18.2507
2000's14 (36.84)29.6817
2010's12 (31.58)24.3611
2020's3 (7.89)2.80

Authors

AuthorsStudies
Denny, WA; Gynther, M; Huttunen, J; Huttunen, KM; Puris, E; Spicer, JA1
Juárez-López, D; Schcolnik-Cabrera, A1
Ahmed, A; Alhusayan, M; Asangani, IA; Busino, L; Callahan, CG; Chinnaiyan, AM; Cieslik, M; Das, CK; Deng, Q; Frohner, IE; Islam, S; Linauer, S; Mitchell-Velasquez, E; Mudrak, I; Narla, G; Natesan, R; O'Connor, CM; Ogris, E; Rainey, J; Rasool, RU; Rebernick, R; Sangodkar, J; Sauter, G; Siddiqui, J; Simon, R; Suhan, TK; Taylor, DJ; Thomas, D; Verma, BK; Wang, S; Zawacki, KP1
Chen, Y; D'Hyon, S; Davis, RA; Gordon, S; Guan, H; Holst, J; Huxley, C; Lum, KY; Si, M; Wahi, K; Wang, M; Wang, Q; Wang, X; White, JM; Wibowo, M1
Davis, RA; Hofmann, A; Holst, J; Wang, Q; White, JM; Wibowo, M1
Chen, J; Han, B; Ide, H; Inoue, S; Izumi, K; Kashiwagi, E; Li, P; Miyamoto, H; Mizushima, T1
Jain, N; Katoch, P; Mehta, PP; Ray, A1
Ding, J; Fu, K; Gan, W; Han, R; Han, X; Jiang, K; Li, D; Wu, J; Zhang, L1
Bailey, CG; Holst, J; Moran, AM; Rasko, JEJ; Wang, Q; Zhang, BK1
Ahmad, H; Alam, SM; Chou, YW; Kumar, S; Lin, MF; Muniyan, S; Zhang, L1
Bailey, CG; Buchanan, G; Fazli, L; Feng, YJ; Gleave, M; Holst, J; Lehman, ML; Li, E; Metierre, C; Nelson, CC; Rasko, JE; Ritchie, W; Tiffen, J; Wang, Q1
Tee, AR1
Bailey, CG; Bonham, S; Font, J; Grkovic, T; Holst, J; Jormakka, M; Moran, AM; Pouwer, RH; Quinn, RJ; Rasko, JE; Ryan, RM; Wang, Q1
Bi, D; Cui, M; Han, L; Jia, Y; Liu, S; Liu, Z; Niu, Z; Wang, X; Zhang, Y1
Anthony, DC; Glinskii, OV; Glinsky, GV; Glinsky, VV; Mawhinney, TP; Mossine, VV; Pienta, KJ; Sud, S1
Boyle, P; English, DR; Giles, GG; Hopper, JL; McCredie, MR; Morris, H; Neufing, P; Severi, G; Southey, MC; Tesoriero, A; Tilley, W1
Papo, N; Shai, Y1
Feng, Z; Iwasaki, L; Noonan, EA; Ostrander, EA; Sabacan, LP; Shu, J; Stanford, JL1
Adler, D; Fick, G; Hughes, RM; Kanji, N; Trpkov, K1
Buehrer, BM; Fletterick, RJ; Grøn, H; Hur, E; Payne, ES; Pfaff, SJ1
Baxter, JD; Buehrer, BM; Delgado-Rodrigues, E; Estébanez-Perpiñá, E; Fletterick, RJ; Guy, RK; Mar, E; Moore, JM; Nguyen, P; Webb, P1
Klibanov, AL; Lu, E; Modzelewski, RA; Villanueva, FS; Wagner, WR; Weller, GE; Wong, MK1
Glinskii, OV; Glinsky, GV; Glinsky, VV; Huxley, VH; Pienta, KJ; Raz, A1
Abrahamsson, PA; Ahlgren, G; Gadaleanu, V; Giwercman, A; Giwercman, YL1
Degani, H; Eshhar, Z; Kalchenko, V; Makovitzki, A; Papo, N; Seger, D; Shai, Y1
Buchanan, G; Butler, LM; Caplan, AJ; Mandal, AK; Oen, H; Robzyk, K; Rosen, N; Tilley, WD1
Altshuler, D; Bell, DW; Daly, MB; Freedman, ML; Garber, JE; Godwin, AK; Haber, DA; Haiman, CA; Harris, PL; Haserlat, SM; Henderson, BE; Kim, SH; Le Marchand, L; Niendorf, KB; Olopade, OI; Schiripo, TA; Sgroi, DC; Smith, MR; Wahrer, DC1
Berns, CM; Corry, PM; Erdos, G; Lee, YJ1
Masai, M; Sato, N; Seino, S; Shimazaki, J; Suzuki, H; Watabe, Y1
Barczak, AK; Coyle, JT; Luthi-Carter, R; Speno, H1
Briones, F; Brisbay, S; Herrmann, JL; Logothetis, CJ; McDonnell, TJ1
Batter, S; Casey, D; Febbo, PG; Giovannucci, E; Hennekens, CH; Kantoff, PW; Platz, EA; Stampfer, MJ1
Chu, W; Harvie, S; Ho, M; Jewett, MA; Nam, RK; Narod, SA; Sweet, J; Toi, A; Trachtenberg, J; Vesprini, D1
Hioki, T; Hirano, K; Ishii, K; Sugimura, Y; Tatematsu, M; Usui, S; Yamamoto, H; Yoshida, S1
Pavelić, J; Pavelić, K; Zgradić, I1
Byerley, LO; Heber, D; Rajfer, J; Steiner, B; Swerdloff, RS; Tayek, JA1
Hartley-Asp, B; Kruse, E1
Hirokawa, I; Ichikawa, T; Ishihara, Y1

Reviews

2 review(s) available for leucine and Cancer of Prostate

ArticleYear
Dual contribution of the mTOR pathway and of the metabolism of amino acids in prostate cancer.
    Cellular oncology (Dordrecht), 2022, Volume: 45, Issue:5

    Topics: Amino Acids; Arginine; Carbohydrates; Glutamine; Humans; Leucine; Lipids; Male; Proline; Prostatic Neoplasms; Sarcosine; Serine; TOR Serine-Threonine Kinases

2022
ELAC2/HPC2 polymorphisms, prostate-specific antigen levels, and prostate cancer.
    Journal of the National Cancer Institute, 2003, Jun-04, Volume: 95, Issue:11

    Topics: Aged; Alanine; Case-Control Studies; Genetic Predisposition to Disease; Heterozygote; Homozygote; Humans; Leucine; Linear Models; Logistic Models; Male; Middle Aged; Neoplasm Proteins; Odds Ratio; Polymorphism, Genetic; Prostate-Specific Antigen; Prostatic Neoplasms; Research Design; Risk Assessment; Risk Factors; Serine; Threonine

2003

Trials

1 trial(s) available for leucine and Cancer of Prostate

ArticleYear
The V89L polymorphism in the 5alpha-reductase type 2 gene and risk of prostate cancer.
    Cancer research, 1999, Dec-01, Volume: 59, Issue:23

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Anticarcinogenic Agents; Aspirin; beta Carotene; Boston; Double-Blind Method; Heart Diseases; Humans; Isoenzymes; Leucine; Male; Middle Aged; Neoplasms; Polymorphism, Genetic; Prostatic Neoplasms; Risk Factors; Valine; White People

1999

Other Studies

35 other study(ies) available for leucine and Cancer of Prostate

ArticleYear
A Selective and Slowly Reversible Inhibitor of l-Type Amino Acid Transporter 1 (LAT1) Potentiates Antiproliferative Drug Efficacy in Cancer Cells.
    Journal of medicinal chemistry, 2016, 06-23, Volume: 59, Issue:12

    Topics: Animals; Antineoplastic Agents; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Imidazoles; Large Neutral Amino Acid-Transporter 1; Male; MCF-7 Cells; Mice; Molecular Structure; Prostatic Neoplasms; Pyridines; Structure-Activity Relationship

2016
Loss of LCMT1 and biased protein phosphatase 2A heterotrimerization drive prostate cancer progression and therapy resistance.
    Nature communications, 2023, 08-29, Volume: 14, Issue:1

    Topics: Androgen Antagonists; Humans; Leucine; Male; Methyltransferases; Prostate; Prostatic Neoplasms; Protein Phosphatase 2

2023
Synthesis of bilocularin A carbamate derivatives and their evaluation as leucine transport inhibitors in prostate cancer cells.
    Phytochemistry, 2020, Volume: 179

    Topics: Australia; Carbamates; Humans; Leucine; Male; Molecular Structure; Prostatic Neoplasms; Sesquiterpenes

2020
Celastrofurans A-G: Dihydro-β-agarofurans from the Australian Rainforest Vine Celastrus subspicata and Their Inhibitory Effect on Leucine Transport in Prostate Cancer Cells.
    Journal of natural products, 2017, 06-23, Volume: 80, Issue:6

    Topics: Amino Acid Transport Systems; Australia; Celastrus; Crystallography, X-Ray; Humans; Leucine; Male; Molecular Structure; Plant Leaves; Prostatic Neoplasms; Rainforest; Sesquiterpenes

2017
The interaction between androgen receptor and semenogelin I: a synthetic LxxLL peptide antagonist inhibits the growth of prostate cancer cells.
    British journal of cancer, 2018, 02-06, Volume: 118, Issue:3

    Topics: Alanine; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chlorides; Dihydrotestosterone; Humans; Leucine; Male; Mutation; Peptides; Prostatic Neoplasms; Receptors, Androgen; Seminal Vesicle Secretory Proteins; Transcription, Genetic; Zinc Compounds

2018
Dileucine-like motifs in the C-terminal tail of connexin32 control its endocytosis and assembly into gap junctions.
    Journal of cell science, 2018, 03-02, Volume: 131, Issue:5

    Topics: Amino Acid Motifs; Cell Line, Tumor; Cell Polarity; Clathrin; Connexins; Endocytosis; Epithelial Cells; Gap Junction beta-1 Protein; Gap Junctions; Humans; Leucine; Male; Pancreatic Neoplasms; Prostatic Neoplasms

2018
piRNA-DQ722010 contributes to prostate hyperplasia of the male offspring mice after the maternal exposed to microcystin-leucine arginine.
    The Prostate, 2019, Volume: 79, Issue:7

    Topics: Animals; Arginine; Argonaute Proteins; Bacterial Toxins; Cell Line, Tumor; Cyanobacteria Toxins; Disease Models, Animal; Drinking Water; Epithelial Cells; Female; Fresh Water; Hyperplasia; Leucine; Male; Marine Toxins; Maternal Exposure; Mice; Mice, Inbred BALB C; Microarray Analysis; Microcystins; Phosphatidylinositol 3-Kinases; Pregnancy; Prostate; Prostatic Neoplasms; Protein Isoforms; Proto-Oncogene Proteins c-akt; RNA, Small Interfering; Signal Transduction; Water Pollution

2019
EGF-activated PI3K/Akt signalling coordinates leucine uptake by regulating LAT3 expression in prostate cancer.
    Cell communication and signaling : CCS, 2019, 07-25, Volume: 17, Issue:1

    Topics: Amino Acid Transport Systems, Basic; Biological Transport; Cell Proliferation; Epidermal Growth Factor; Gene Expression Regulation, Neoplastic; Humans; Leucine; Male; PC-3 Cells; Phosphatidylinositol 3-Kinases; Phosphoproteins; Prostatic Neoplasms; Protein Transport; Proto-Oncogene Proteins c-akt; Signal Transduction

2019
Androgens upregulate Cdc25C protein by inhibiting its proteasomal and lysosomal degradation pathways.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Androgens; cdc25 Phosphatases; Cell Cycle Proteins; Cell Line, Tumor; Dihydrotestosterone; Humans; Leucine; Leupeptins; Lysosomes; Male; Prostatic Neoplasms; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Receptors, Androgen; Transcriptome; Up-Regulation

2013
Targeting amino acid transport in metastatic castration-resistant prostate cancer: effects on cell cycle, cell growth, and tumor development.
    Journal of the National Cancer Institute, 2013, Oct-02, Volume: 105, Issue:19

    Topics: Activating Transcription Factor 4; Amino Acid Transport Systems, Basic; Amino Acids; Animals; Antineoplastic Agents, Hormonal; Biological Transport; Cell Cycle; Computer Simulation; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Leucine; Luminescent Measurements; Male; Mechanistic Target of Rapamycin Complex 1; Mice; Multiprotein Complexes; Neoadjuvant Therapy; Neoplasms, Hormone-Dependent; Orchiectomy; Prostatic Neoplasms; Protein Array Analysis; Receptors, Androgen; Signal Transduction; TOR Serine-Threonine Kinases; Up-Regulation; Xenograft Model Antitumor Assays

2013
Metastatic castration-resistant prostate cancer hungers for leucine.
    Journal of the National Cancer Institute, 2013, Oct-02, Volume: 105, Issue:19

    Topics: Activating Transcription Factor 4; Amino Acid Transport Systems, Basic; Amino Acids; Animals; Antineoplastic Agents, Hormonal; Humans; Leucine; Male; Neoadjuvant Therapy; Prostatic Neoplasms; Receptors, Androgen

2013
Monoterpene glycoside ESK246 from Pittosporum targets LAT3 amino acid transport and prostate cancer cell growth.
    ACS chemical biology, 2014, Jun-20, Volume: 9, Issue:6

    Topics: Amino Acid Transport Systems, Basic; Animals; Antineoplastic Agents; Apoptosis; Biological Transport; Blotting, Western; Cell Proliferation; Female; Glycosides; Humans; Large Neutral Amino Acid-Transporter 1; Leucine; Male; Mechanistic Target of Rapamycin Complex 1; Monoterpenes; Multiprotein Complexes; Oocytes; Prostatic Neoplasms; Rosales; TOR Serine-Threonine Kinases; Tumor Cells, Cultured; Xenopus laevis

2014
Ubenimex inhibits cell proliferation, migration and invasion by inhibiting the expression of APN and inducing autophagic cell death in prostate cancer cells.
    Oncology reports, 2016, Volume: 35, Issue:4

    Topics: Animals; Antineoplastic Agents; Autophagy; CD13 Antigens; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; Leucine; Male; Mice; Mice, Nude; Neoplasm Invasiveness; Prostatic Neoplasms; Xenograft Model Antitumor Assays

2016
Inhibition of prostate cancer bone metastasis by synthetic TF antigen mimic/galectin-3 inhibitor lactulose-L-leucine.
    Neoplasia (New York, N.Y.), 2012, Volume: 14, Issue:1

    Topics: Animals; Antigens, Tumor-Associated, Carbohydrate; Antineoplastic Agents; Biomimetic Materials; Bone Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Galectin 3; Humans; Lactulose; Leucine; Male; Mice; Mice, SCID; Prostatic Neoplasms; Xenograft Model Antitumor Assays

2012
New lytic peptides based on the D,L-amphipathic helix motif preferentially kill tumor cells compared to normal cells.
    Biochemistry, 2003, Aug-12, Volume: 42, Issue:31

    Topics: Anti-Infective Agents; Antimicrobial Cationic Peptides; Cell Death; Cell Membrane; Fluoresceins; Hemolysis; Humans; Leucine; Lysine; Male; Melanoma, Experimental; Membrane Lipids; Microscopy, Confocal; Mitomycin; Phosphatidylserines; Prostatic Neoplasms; Protein Conformation; Rhodamines; Skin; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Structure-Activity Relationship; Surface Plasmon Resonance; Tumor Cells, Cultured

2003
Association of HPC2/ELAC2 polymorphisms with risk of prostate cancer in a population-based study.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2003, Volume: 12, Issue:9

    Topics: Adenocarcinoma; Adult; Alleles; Case-Control Studies; Gene Frequency; Genetic Variation; Homozygote; Humans; Leucine; Male; Middle Aged; Mutation, Missense; Neoplasm Proteins; Neoplasm Staging; Polymorphism, Genetic; Prostatic Neoplasms; Risk Factors; White People

2003
HPC2/ELAC2 gene variants associated with incident prostate cancer.
    Journal of human genetics, 2003, Volume: 48, Issue:12

    Topics: Age Factors; Alleles; Genetic Predisposition to Disease; Genetic Variation; Genotype; Heterozygote; Homozygote; Humans; Leucine; Logistic Models; Male; Neoplasm Proteins; Prostate; Prostatic Neoplasms; Risk; Serine; Threonine

2003
Recognition and accommodation at the androgen receptor coactivator binding interface.
    PLoS biology, 2004, Volume: 2, Issue:9

    Topics: Amino Acid Motifs; Amino Acid Sequence; Carrier Proteins; Crystallography, X-Ray; Cytoskeletal Proteins; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; Kinetics; Leucine; LIM Domain Proteins; Male; Molecular Sequence Data; Nerve Tissue Proteins; Nuclear Receptor Coactivator 2; Nuclear Receptor Coactivators; Oncogene Proteins; Peptide Library; Peptides; Prostatic Neoplasms; Protein Binding; Protein Conformation; Protein Structure, Secondary; Receptors, Androgen; Receptors, Estrogen; Receptors, Glucocorticoid; Sequence Homology, Amino Acid; Surface Plasmon Resonance; Thyroid Hormone Receptors beta; Time Factors; Transcription Factors

2004
The molecular mechanisms of coactivator utilization in ligand-dependent transactivation by the androgen receptor.
    The Journal of biological chemistry, 2005, Mar-04, Volume: 280, Issue:9

    Topics: Amino Acid Motifs; Amino Acid Sequence; Cells, Cultured; Crystallography, X-Ray; Drug Design; Electrons; Gene Library; Genes, Reporter; Glutathione Transferase; HeLa Cells; Humans; Kinetics; Leucine; Ligands; Luciferases; Male; Models, Molecular; Molecular Sequence Data; Peptides; Prostatic Neoplasms; Protein Binding; Protein Structure, Tertiary; Receptors, Androgen; Transcriptional Activation; Transfection

2005
Ultrasonic imaging of tumor angiogenesis using contrast microbubbles targeted via the tumor-binding peptide arginine-arginine-leucine.
    Cancer research, 2005, Jan-15, Volume: 65, Issue:2

    Topics: Animals; Arginine; Carcinoma, Squamous Cell; Echocardiography; Endothelium, Vascular; Fluorescein; Humans; Leucine; Male; Mice; Mice, Inbred C3H; Mice, Nude; Microbubbles; Myocardium; Neoplasm Transplantation; Neovascularization, Pathologic; NIH 3T3 Cells; Oligopeptides; Prostatic Neoplasms; Transplantation, Heterologous

2005
Mechanical entrapment is insufficient and intercellular adhesion is essential for metastatic cell arrest in distant organs.
    Neoplasia (New York, N.Y.), 2005, Volume: 7, Issue:5

    Topics: Animals; Antibodies; Antibodies, Monoclonal; Bone Neoplasms; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Citrus; Female; Galectin 3; Humans; Leucine; Lung Neoplasms; Male; Mice; Mice, Inbred ICR; Mice, SCID; Neoplasm Metastasis; Neoplasm Transplantation; Pectins; Prostatic Neoplasms

2005
The 5alpha-reductase type II A49T and V89L high-activity allelic variants are more common in men with prostate cancer compared with the general population.
    European urology, 2005, Volume: 48, Issue:4

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Aged; Alanine; Alleles; Arginine; Biomarkers, Tumor; Case-Control Studies; Dihydrotestosterone; Disease Progression; Follow-Up Studies; Genetic Predisposition to Disease; Genotype; Glutamine; Humans; Leucine; Luteinizing Hormone; Male; Middle Aged; Point Mutation; Polymorphism, Genetic; Prostatic Hyperplasia; Prostatic Neoplasms; Receptors, Androgen; Risk Factors; Sex Hormone-Binding Globulin; Sweden; Terminal Repeat Sequences; Testosterone; Threonine; Valine

2005
Inhibition of tumor growth and elimination of multiple metastases in human prostate and breast xenografts by systemic inoculation of a host defense-like lytic peptide.
    Cancer research, 2006, May-15, Volume: 66, Issue:10

    Topics: Adenocarcinoma; Amino Acid Sequence; Animals; Breast Neoplasms; Cell Growth Processes; Cell Line, Tumor; Female; Humans; Leucine; Lung Neoplasms; Lysine; Male; Membrane Potentials; Mice; Mice, SCID; Neoplasm Metastasis; Peptides; Phosphatidylserines; Prostate-Specific Antigen; Prostatic Neoplasms; Xenograft Model Antitumor Assays

2006
Uncoupling of hormone-dependence from chaperone-dependence in the L701H mutation of the androgen receptor.
    Molecular and cellular endocrinology, 2007, Mar-30, Volume: 268, Issue:1-2

    Topics: Androgens; Cell Line, Tumor; Histidine; HSP90 Heat-Shock Proteins; Humans; Leucine; Ligands; Male; Mutant Proteins; Mutation; Prostatic Neoplasms; Protein Structure, Tertiary; Receptors, Androgen; Saccharomyces cerevisiae Proteins; Transcriptional Activation; Yeasts

2007
Genetic and functional analysis of CHEK2 (CHK2) variants in multiethnic cohorts.
    International journal of cancer, 2007, Dec-15, Volume: 121, Issue:12

    Topics: Adult; Age of Onset; Aged; Asian People; Black or African American; Breast Neoplasms; Case-Control Studies; Checkpoint Kinase 2; DNA Mutational Analysis; DNA, Complementary; Female; Gene Frequency; Genetic Predisposition to Disease; Germ-Line Mutation; Hawaii; Hispanic or Latino; Histidine; Humans; Isoleucine; Leucine; Male; Middle Aged; Mutation; Mutation, Missense; Predictive Value of Tests; Proline; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Risk Assessment; Risk Factors; Threonine; Tyrosine; United States; White People

2007
Effect of isoquinolinesulfonamides on heat shock gene expression during heating at 41 degrees C in human carcinoma cell lines.
    Biochemical and biophysical research communications, 1994, Mar-15, Volume: 199, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Blotting, Northern; Breast Neoplasms; Cyclic AMP-Dependent Protein Kinases; Female; Gene Expression Regulation, Neoplastic; Heat-Shock Proteins; Hot Temperature; Humans; Isoquinolines; Kinetics; Leucine; Male; Piperazines; Prostatic Neoplasms; Protein Kinase C; RNA, Messenger; Sulfonamides; Tumor Cells, Cultured

1994
Androgen receptor gene mutations in human prostate cancer.
    The Journal of steroid biochemistry and molecular biology, 1993, Volume: 46, Issue:6

    Topics: Adenocarcinoma; Alanine; Amino Acid Sequence; Base Sequence; DNA Primers; DNA-Binding Proteins; DNA, Neoplasm; Exons; Genetic Variation; Histidine; Humans; Leucine; Male; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Prostatic Neoplasms; Receptors, Androgen; Threonine

1993
Hydrolysis of the neuropeptide N-acetylaspartylglutamate (NAAG) by cloned human glutamate carboxypeptidase II.
    Brain research, 1998, Jun-08, Volume: 795, Issue:1-2

    Topics: Animals; Antigens, Surface; Binding, Competitive; Carboxypeptidases; Chelating Agents; Cloning, Molecular; Cobalt; Coumarins; Dipeptides; Edetic Acid; Folic Acid; Glutamate Carboxypeptidase II; Histamine H1 Antagonists; Humans; Hydrolysis; Isocoumarins; Kinetics; Leucine; Male; Neuropeptides; Pepstatins; Phenanthrolines; Prostatic Neoplasms; Protease Inhibitors; Rats; Serine Proteinase Inhibitors; Substrate Specificity; Synaptic Transmission; Tumor Cells, Cultured

1998
Prostate carcinoma cell death resulting from inhibition of proteasome activity is independent of functional Bcl-2 and p53.
    Oncogene, 1998, Dec-03, Volume: 17, Issue:22

    Topics: Aldehydes; Apoptosis Regulatory Proteins; beta Catenin; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Cell Death; Cytoskeletal Proteins; DNA-Binding Proteins; Dose-Response Relationship, Drug; Humans; I-kappa B Proteins; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Leucine; Male; Mitogen-Activated Protein Kinases; NF-kappa B; NF-KappaB Inhibitor alpha; Peptide Hydrolases; Peptides; Prostatic Neoplasms; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-jun; Signal Transduction; Trans-Activators; Transcription Factor RelA; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Ubiquitins

1998
V89L polymorphism of type-2, 5-alpha reductase enzyme gene predicts prostate cancer presence and progression.
    Urology, 2001, Volume: 57, Issue:1

    Topics: Aged; Alleles; Cholestenone 5 alpha-Reductase; Disease Progression; Follow-Up Studies; Genetic Markers; Humans; Leucine; Male; Middle Aged; Neoplasm Proteins; Neoplasm Recurrence, Local; Odds Ratio; Oxidoreductases; Phenotype; Polymorphism, Genetic; Prostatic Neoplasms; Valine

2001
Aminopeptidase N regulated by zinc in human prostate participates in tumor cell invasion.
    International journal of cancer, 2001, Apr-01, Volume: 92, Issue:1

    Topics: Amino Acid Sequence; CD13 Antigens; Copper; Dose-Response Relationship, Drug; Edetic Acid; Egtazic Acid; Enzyme Inhibitors; Epithelium; Humans; Immunohistochemistry; Leucine; Male; Neoplasm Invasiveness; Peptide Fragments; Phenanthrolines; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Substrate Specificity; Tumor Cells, Cultured; Zinc

2001
Presence of oestrogen receptors on target cells and antiproliferative activity of estramustine phosphate: positive correlation for human tumours in vitro.
    Journal of cancer research and clinical oncology, 1991, Volume: 117, Issue:3

    Topics: Cell Division; Cytosol; DNA, Neoplasm; Dose-Response Relationship, Drug; Estramustine; Female; Humans; Kidney Neoplasms; Leucine; Male; Prostatic Neoplasms; Protein Biosynthesis; Receptors, Estrogen; RNA, Neoplasm; Thymidine; Tumor Cells, Cultured; Uridine; Uterine Cervical Neoplasms; Uterine Neoplasms

1991
Nutritional and metabolic effects of gonadotropin-releasing hormone agonist treatment for prostate cancer.
    Metabolism: clinical and experimental, 1990, Volume: 39, Issue:12

    Topics: Aged; Body Composition; Buserelin; Energy Metabolism; Gonadotropin-Releasing Hormone; Hormones; Humans; Leucine; Male; Nutritional Physiological Phenomena; Prostatic Neoplasms

1990
The effect of estramustine, nor-nitrogen mustard and tauromustine on macromolecular labelling in the human prostatic tumour cell line 1013L.
    Pharmacology & toxicology, 1989, Volume: 64, Issue:1

    Topics: Affinity Labels; Biological Transport; Cell Survival; DNA, Neoplasm; Estramustine; Humans; Leucine; Macromolecular Substances; Male; Nitrogen Mustard Compounds; Nitrosourea Compounds; Nucleotides; Prostatic Neoplasms; RNA, Neoplasm; Taurine; Tumor Cells, Cultured

1989
[Clinical studies of bestatin on genitourinary cancer].
    The Japanese journal of antibiotics, 1985, Volume: 38, Issue:1

    Topics: Adjuvants, Immunologic; Aged; Antibiotics, Antineoplastic; Female; Humans; Kidney Neoplasms; Leucine; Male; Middle Aged; Penile Neoplasms; Prostatic Neoplasms; Ureteral Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms

1985