leucine has been researched along with Cachexia in 42 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 7 (16.67) | 18.7374 |
1990's | 7 (16.67) | 18.2507 |
2000's | 6 (14.29) | 29.6817 |
2010's | 17 (40.48) | 24.3611 |
2020's | 5 (11.90) | 2.80 |
Authors | Studies |
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Busanello, ENB; Castelucci, BG; Chiocchetti, GME; Consonni, SR; de Oliveira, ALR; de Sousa, LM; Gomes-Marcondes, MCC; Marques, AC; Oroy, L; Salgado, CM; Suarez, PS; Vercesi, AE; Viana, LR; Vieira, AS; Vieira, WF | 1 |
Beaudry, AG; Law, ML | 1 |
Alves, TC; Bork, U; Chavakis, T; Distler, M; Funk, AM; Jonas, S; Kahlert, C; Komorek, F; Meisterfeld, R; Menschikowski, M; Mirtschink, P; Seifert, AM; Seifert, L; Tritchkova, G; von Bechtolsheim, F; von Renesse, J; Weitz, J | 1 |
Argilès, J; Faber, J; Laviano, A; Meijerink, J; Plas, RLC; Poland, M; van Dijk, M; van Helvoort, A; van Norren, K; Witkamp, RF | 1 |
Ballmer, PE; Gaeumann, S; Gisi, D; Imoberdorf, R; Meffert, PJ; Pless, M; Ruehlin, M; Schmocker, M; Storck, LJ | 1 |
Dos Santos, GS; Gomes-Marcondes, MCC; Manhe, BS; Miyaguti, NADS; Oliveira, SCP; Stanisic, D; Tasic, L | 1 |
Cruz, B; Gomes-Marcondes, MCC; Oliveira, A | 1 |
Amagai, T; Haji, S; Kitagawa, M | 1 |
Antoun, S; Raynard, B | 1 |
de Oliveira, SCP; Gomes-Marcondes, MCC; Miyaguti, NADS | 1 |
Cruz, B; Gomes-Marcondes, MCC; Oliveira, A; Ventrucci, G | 1 |
Gomes-Marcondes, MCC; Miyaguti, NADS; Oliveira, SCP | 1 |
Gomes-Marcondes, MC; Gonçalves, EM; Salomão, EM | 1 |
Chevalier, S; Winter, A | 1 |
Boschero, AC; Bosqueiro, JR; Rafacho, A; Violato, NM | 1 |
Aereas, MA; Ferreira Ramos, LA; Gomes-Marcondes, MC; Salomão, EM; Tomasin, R; Toneto, AT | 1 |
Canevarolo, R; Gomes-Marcondes, MC; Lubaczeuski, C; Luiz, AC; Soares, RF; Viana, LR; Zeri, AC | 1 |
Argilés, JM; Arts, K; Faber, J; Gorselink, M; Jansen, H; Kegler, D; Laviano, A; Luiking, Y; van der Beek, EM; van Helvoort, A; van Norren, K | 1 |
Gomes-Marcondes, MC; Salomão, EM; Silva, GO; Toneto, AT | 1 |
Argilès, JM; Deutz, NE; Gorselink, M; Haagsman, HP; Kegler, D; Laviano, A; Luiking, YC; Peters, SJ; van Bergenhenegouwen, J; van Helvoort, A; van Norren, K | 1 |
Bird, SP; Keogh, JW; MacLeod, RD; Rogers, ES; Stewart, J | 1 |
Breen, L; Phillips, SM | 1 |
Gomes-Marcondes, MC; Salomão, EM | 1 |
Cooper, JC; Cury, L; Gomes-Marcondes, MC; Toledo, MT; Ventrucci, G | 1 |
Gomes-Marcondes, MC; Mello, MA; Ventrucci, G | 2 |
Eley, HL; Russell, ST; Tisdale, MJ | 1 |
Edwards, RH; Emery, PW; Halliday, D; Rennie, MJ; Souhami, RL | 1 |
Waterhouse, C | 1 |
Butterfield, GE; Harrison, D; Hoffman, AR; Lieberman, SA | 1 |
Argilés, JM; Carbó, N; Costelli, P; García-Martínez, C; Llovera, M; López-Soriano, FJ | 1 |
Bistrian, BR; Ling, PR; Schwartz, JH | 1 |
Calder, AG; de Souza, G; Griffin, GE; Kurpad, AV; Macallan, DC; McNurlan, MA; Shetty, PS | 1 |
Areas, MA; Cury, L; Gomes-Marcondes, MC; Honma, HN | 1 |
Drake, JL; Smith, HJ; Tisdale, MJ; Whitehouse, AS | 1 |
Douglas, RG; Humberstone, DA; Koea, J; Shaw, JH | 1 |
O'Keefe, SJ; Ogden, J; Ramjee, G; Rund, J | 1 |
Bistrian, BR; Blackburn, GL; Hunter, DC; Weintraub, M | 1 |
Bistrian, BR; Blackburn, GL; Hehir, DJ; Martin, R; Moldawer, LL; Tayek, JA | 1 |
Gold, J | 1 |
Gorschboth, CM; Inculet, RI; Leskiw, M; Maher, M; Norton, JA; Peacock, JL; Stein, TP | 1 |
Lazo, PA | 1 |
3 review(s) available for leucine and Cachexia
Article | Year |
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Leucine Supplementation in Cancer Cachexia: Mechanisms and a Review of the Pre-Clinical Literature.
Topics: Cachexia; Diet; Dietary Supplements; Humans; Leucine; Muscle, Skeletal; Neoplasms | 2022 |
Do patients with advanced cancer have any potential for protein anabolism in response to amino acid therapy?
Topics: Amino Acids; Amino Acids, Branched-Chain; Anabolic Agents; Cachexia; Dietary Proteins; Dietary Supplements; Humans; Inflammation; Leucine; Muscular Atrophy; Neoplasms; Proteins | 2014 |
Nutrient interaction for optimal protein anabolism in resistance exercise.
Topics: Cachexia; Dietary Proteins; Humans; Hypertrophy; Leucine; Muscle Proteins; Muscular Atrophy; Protein Biosynthesis; Resistance Training | 2012 |
5 trial(s) available for leucine and Cachexia
Article | Year |
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Effect of a leucine-rich supplement in combination with nutrition and physical exercise in advanced cancer patients: A randomized controlled intervention trial.
Topics: Adult; Aged; Aged, 80 and over; Cachexia; Combined Modality Therapy; Dietary Supplements; Exercise; Exercise Test; Exercise Therapy; Fatigue; Female; Hand Strength; Humans; Leucine; Male; Middle Aged; Neoplasms; Nutrition Therapy; Nutritional Status; Patient Compliance; Physical Functional Performance; Quality of Life; Treatment Outcome | 2020 |
A randomised feasibility study of EPA and Cox-2 inhibitor (Celebrex) versus EPA, Cox-2 inhibitor (Celebrex), resistance training followed by ingestion of essential amino acids high in leucine in NSCLC cachectic patients--ACCeRT study.
Topics: Adult; Amino Acids, Essential; Cachexia; Carcinoma, Non-Small-Cell Lung; Celecoxib; Combined Modality Therapy; Cyclooxygenase 2 Inhibitors; Dietary Supplements; Eicosapentaenoic Acid; Feasibility Studies; Female; Humans; Leucine; Lung Neoplasms; Male; Middle Aged; New Zealand; Patient Satisfaction; Prospective Studies; Pyrazoles; Resistance Training; Sulfonamides | 2011 |
Anabolic effects of recombinant insulin-like growth factor-I in cachectic patients with the acquired immunodeficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anthropometry; Body Mass Index; Cachexia; Carrier Proteins; CD4 Antigens; Dose-Response Relationship, Drug; Energy Metabolism; Glycine; Growth Hormone; Humans; Insulin-Like Growth Factor Binding Protein 2; Insulin-Like Growth Factor Binding Proteins; Insulin-Like Growth Factor I; Leucine; Lymphocytes; Male; Middle Aged; Nitrogen; Recombinant Proteins; Time Factors; Tumor Necrosis Factor-alpha | 1994 |
Branched chain amino acids as the protein component of parenteral nutrition in cancer cachexia.
Topics: Abdominal Neoplasms; Adenocarcinoma; Amino Acids; Amino Acids, Branched-Chain; Cachexia; Humans; Leucine; Parenteral Nutrition, Total; Prospective Studies; Proteins; Random Allocation; Tyrosine | 1989 |
Improved protein kinetics and albumin synthesis by branched chain amino acid-enriched total parenteral nutrition in cancer cachexia. A prospective randomized crossover trial.
Topics: Abdominal Neoplasms; Adenocarcinoma; Adult; Aged; Albumins; Amino Acids; Amino Acids, Branched-Chain; Cachexia; Clinical Trials as Topic; Energy Intake; Female; Humans; Kinetics; Leucine; Male; Middle Aged; Nitrogen; Nutritional Requirements; Parenteral Nutrition, Total; Proteins; Random Allocation | 1986 |
34 other study(ies) available for leucine and Cachexia
Article | Year |
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Leucine-Rich Diet Improved Muscle Function in Cachectic Walker 256 Tumour-Bearing Wistar Rats.
Topics: Animals; Cachexia; Dietary Supplements; Forkhead Box Protein O1; Humans; Inflammation; Leucine; Muscle Proteins; Muscular Atrophy; Neoplasms; Proteolysis; Quality of Life; Rats; Tripartite Motif Proteins; Ubiquitin-Protein Ligases | 2021 |
Tumour catabolism independent of malnutrition and inflammation in upper GI cancer patients revealed by longitudinal metabolomics.
Topics: 3-Hydroxybutyric Acid; Cachexia; Gastrointestinal Neoplasms; Humans; Inflammation; Leucine; Malnutrition; Metabolomics; Pancreatic Neoplasms | 2023 |
A Diet Rich in Fish Oil and Leucine Ameliorates Hypercalcemia in Tumour-Induced Cachectic Mice.
Topics: Animals; Cachexia; Calcium; Diet; Dinoprostone; Disease Models, Animal; Fish Oils; Hypercalcemia; Leucine; Male; Mice; Muscle, Skeletal; Neoplasms; Parathyroid Hormone-Related Protein | 2019 |
Serum and Muscle
Topics: Amino Acids; Animals; Cachexia; Diet; Dietary Supplements; Energy Metabolism; Female; Lactates; Leucine; Lipid Metabolism; Male; Maternal Nutritional Physiological Phenomena; Maternal-Fetal Exchange; Metabolome; Muscle, Skeletal; Neoplasms; Pregnancy; Proton Magnetic Resonance Spectroscopy; Rats, Wistar | 2020 |
L-leucine dietary supplementation modulates muscle protein degradation and increases pro-inflammatory cytokines in tumour-bearing rats.
Topics: Animals; Body Composition; Cachexia; Carcinoma 256, Walker; Cytokines; Diet; Dietary Supplements; Inflammation; Interleukin-4; Interleukin-6; Leucine; Muscle, Skeletal; Protein Biosynthesis; Proteins; Quality of Life; Rats; Rats, Wistar | 2017 |
High Serum Essential Amino Acids as a Predictor of Skeletal Muscle Depletion in Patients With Cachexia and Advanced Gastrointestinal Cancers.
Topics: Aged; Amino Acids, Essential; Antineoplastic Agents; Biomarkers; C-Reactive Protein; Cachexia; Disease Progression; Female; Gastrointestinal Neoplasms; Humans; Isoleucine; Japan; Leucine; Male; Medical Records; Neoplasm Staging; Psoas Muscles; Retrospective Studies; Risk; Sarcopenia; Tomography, X-Ray Computed; Up-Regulation | 2017 |
Muscle protein anabolism in advanced cancer patients: response to protein and amino acids support, and to physical activity.
Topics: Animals; Antineoplastic Agents; Cachexia; Combined Modality Therapy; Dietary Proteins; Dietary Supplements; Disease Models, Animal; Exercise; Exercise Therapy; Humans; Leucine; Muscle Proteins; Muscle, Skeletal; Neoplasm Staging; Neoplasms; Physical Conditioning, Animal; Postoperative Complications; Protein Biosynthesis | 2018 |
Maternal nutritional supplementation with fish oil and/or leucine improves hepatic function and antioxidant defenses, and minimizes cachexia indexes in Walker-256 tumor-bearing rats offspring.
Topics: Alkaline Phosphatase; Animal Nutritional Physiological Phenomena; Animals; Antioxidants; Cachexia; Diet; Dietary Supplements; Fatty Acids, Omega-3; Female; Fish Oils; Leucine; Liver; Male; Malondialdehyde; Maternal Nutritional Physiological Phenomena; Oxidative Stress; Pregnancy; Protein Biosynthesis; Rats, Wistar; Superoxide Dismutase; Transaminases | 2018 |
A leucine-rich diet modulates the mTOR cell signalling pathway in the gastrocnemius muscle under different Walker-256 tumour growth conditions.
Topics: Animals; Cachexia; Carcinoma 256, Walker; Dietary Supplements; Female; Leucine; Muscle Proteins; Muscle, Skeletal; Proteolysis; Rats; Rats, Wistar; Signal Transduction; TOR Serine-Threonine Kinases | 2019 |
Maternal Leucine-Rich Diet Minimises Muscle Mass Loss in Tumour-bearing Adult Rat Offspring by Improving the Balance of Muscle Protein Synthesis and Degradation.
Topics: Animals; Body Weight; Cachexia; Diet; Eating; Female; Leucine; Male; Mothers; Muscle Proteins; Muscle, Skeletal; Muscles; Neoplasms; Organ Size; Pregnancy; Proteolysis; Rats; Rats, Wistar | 2019 |
Leucine modulates the effect of Walker factor, a proteolysis-inducing factor-like protein from Walker tumours, on gene expression and cellular activity in C2C12 myotubes.
Topics: Alkaline Phosphatase; Animals; Cachexia; Carcinoma 256, Walker; Cathepsin B; Cell Survival; Chymotrypsin; Gene Expression; Leucine; Male; Muscle Fibers, Skeletal; Proteasome Endopeptidase Complex; Protein Biosynthesis; Proteoglycans; Proteolysis; Rats; Rats, Wistar | 2013 |
Higher insulin sensitivity and impaired insulin secretion in cachetic solid ehrlich tumour-bearing mice.
Topics: Animals; Arginine; Cachexia; Carcinoma, Ehrlich Tumor; Glucose; Humans; Insulin; Leucine; Male; Mice | 2014 |
Nutritional leucine supplementation attenuates cardiac failure in tumour-bearing cachectic animals.
Topics: Animals; Apoptosis; Biomarkers; Body Weight; Cachexia; Dietary Supplements; Disease Models, Animal; Electrocardiography; Heart Failure; Leucine; Male; Neoplasms; Nutrition Therapy; Rats | 2016 |
Leucine-rich diet alters the
Topics: Animals; Cachexia; Cell Line, Tumor; Diet; Female; Leucine; Metabolome; Neoplasm Transplantation; Neoplasms; Rats, Wistar; Tumor Burden | 2016 |
Dietary supplementation with a specific combination of high protein, leucine, and fish oil improves muscle function and daily activity in tumour-bearing cachectic mice.
Topics: Adenocarcinoma; Animals; Body Weight; Cachexia; Colonic Neoplasms; Dietary Supplements; Drug Combinations; Fish Oils; Food, Formulated; Leucine; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Motor Activity; Muscle, Skeletal; Proteins | 2009 |
Physical exercise and a leucine-rich diet modulate the muscle protein metabolism in Walker tumor-bearing rats.
Topics: Animals; Body Composition; Body Weight; Cachexia; Carcinoma 256, Walker; Diet; Leucine; Male; Motor Activity; Muscle Proteins; Muscle, Skeletal; Myosin Heavy Chains; Neoplasm Transplantation; Proteasome Endopeptidase Complex; Rats; Rats, Wistar; Swimming; Tumor Burden | 2010 |
Dose-dependent effects of leucine supplementation on preservation of muscle mass in cancer cachectic mice.
Topics: Amino Acids; Animals; Cachexia; Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; Leucine; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Muscle Proteins; Muscles; Neoplasm Transplantation; Neoplasms | 2011 |
Light aerobic physical exercise in combination with leucine and/or glutamine-rich diet can improve the body composition and muscle protein metabolism in young tumor-bearing rats.
Topics: Animals; Cachexia; Carcinoma 256, Walker; Dietary Supplements; Exercise Therapy; Glutamine; Leucine; Male; Neoplasm Transplantation; Physical Conditioning, Animal; Rats; Rats, Wistar; Tumor Burden; Weight Gain | 2012 |
A leucine-supplemented diet improved protein content of skeletal muscle in young tumor-bearing rats.
Topics: Animals; Body Composition; Body Weight; Cachexia; Carcinoma 256, Walker; Dietary Supplements; Leucine; Male; Muscle Proteins; Muscle, Skeletal; Rats; Rats, Wistar | 2003 |
Leucine-rich diet alters the eukaryotic translation initiation factors expression in skeletal muscle of tumour-bearing rats.
Topics: Animals; Cachexia; Carcinoma 256, Walker; Dietary Supplements; Disease Models, Animal; Eukaryotic Initiation Factors; Insulin; Leucine; Muscle, Skeletal; Protein Biosynthesis; Random Allocation; Rats; Rats, Wistar; Reference Values | 2007 |
Effect of branched-chain amino acids on muscle atrophy in cancer cachexia.
Topics: Adaptor Proteins, Signal Transducing; Amino Acids, Branched-Chain; Animals; Cachexia; Carrier Proteins; Cell Cycle Proteins; Cells, Cultured; Eukaryotic Initiation Factor-4E; Eukaryotic Initiation Factor-4G; Eukaryotic Initiation Factors; Leucine; Mice; Mice, Inbred Strains; Muscular Atrophy; Myoblasts; Neoplasms; Phosphoproteins; Phosphorylation; Protein Kinases; Proteoglycans; Time Factors; Valine | 2007 |
Protein synthesis in muscle measured in vivo in cachectic patients with cancer.
Topics: Aged; Cachexia; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Humans; Kidney Neoplasms; Leucine; Lung Neoplasms; Male; Middle Aged; Muscle Proteins; Neoplasms; Protein Biosynthesis; Wilms Tumor | 1984 |
Oxidation and metabolic interconversion in malignant cachexia.
Topics: Amino Acids; Cachexia; Energy Metabolism; Fatty Acids; Gluconeogenesis; Glucose; Humans; Leucine; Neoplasms; Oxidation-Reduction; Proteins | 1981 |
Enhanced leucine oxidation in rats bearing an ascites hepatoma (Yoshida AH-130) and its reversal by clenbuterol.
Topics: Animals; Cachexia; Carbon Dioxide; Clenbuterol; Leucine; Liver Neoplasms, Experimental; Male; Muscles; Organ Size; Rats; Rats, Wistar | 1995 |
Mechanisms of host wasting induced by administration of cytokines in rats.
Topics: Animals; Body Weight; Cachexia; Energy Metabolism; Fasting; Leucine; Liver; Male; Muscle Proteins; Nitrogen; Proteins; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 1997 |
Whole body protein metabolism in human pulmonary tuberculosis and undernutrition: evidence for anabolic block in tuberculosis.
Topics: Adolescent; Adult; Aged; Anthropometry; Cachexia; Cytokines; Deficiency Diseases; Energy Metabolism; Female; Humans; Keto Acids; Leucine; Male; Middle Aged; Oxidation-Reduction; Proteins; Tuberculosis, Pulmonary | 1998 |
Effect of Walker 256 tumor growth on intestinal absorption of leucine, methionine and glucose in newly weaned and mature rats.
Topics: Animals; Cachexia; Carcinoma 256, Walker; Cell Division; Glucose; Intestinal Absorption; Leucine; Methionine; Rats; Time Factors | 1998 |
Effect of a leucine-supplemented diet on body composition changes in pregnant rats bearing Walker 256 tumor.
Topics: Animals; Body Composition; Body Weight; Cachexia; Carcinoma 256, Walker; Collagen; Dietary Supplements; Female; Fetal Weight; Leucine; Muscle, Skeletal; Nitrogen; Pregnancy; Rats; Rats, Wistar; Statistics, Nonparametric | 2001 |
Mechanism of attenuation of skeletal muscle protein catabolism in cancer cachexia by eicosapentaenoic acid.
Topics: Adenocarcinoma; Adenosine Triphosphate; Animals; Cachexia; Calcium; Colonic Neoplasms; Cysteine Proteinase Inhibitors; Eicosapentaenoic Acid; Female; Leucine; Lysosomes; Mice; Muscle Proteins; Muscle, Skeletal; Peptide Hydrolases | 2001 |
Leucine kinetics in patients with benign disease, non-weight-losing cancer, and cancer cachexia: studies at the whole-body and tissue level and the response to nutritional support.
Topics: Adult; Aged; Aged, 80 and over; Cachexia; Clinical Protocols; Fat Emulsions, Intravenous; Female; Humans; Hydrocortisone; Insulin; Intraoperative Period; Kinetics; Leucine; Male; Middle Aged; Muscles; Neoplasms; Proteins; Weight Loss | 1991 |
Contribution of elevated protein turnover and anorexia to cachexia in patients with hepatocellular carcinoma.
Topics: Adolescent; Adult; Aged; Amino Acids; Anorexia; Blood Proteins; Cachexia; Carcinoma, Hepatocellular; Feeding and Eating Disorders; Female; Humans; Leucine; Liver; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Oxidation-Reduction; Protein Biosynthesis; Proteins | 1990 |
Re: Altered leucine metabolism in noncachectic sarcoma patients.
Topics: Cachexia; Humans; Leucine; Sarcoma | 1988 |
Altered leucine metabolism in noncachectic sarcoma patients.
Topics: Adult; Aged; Cachexia; Energy Metabolism; Female; Humans; Kinetics; Leucine; Male; Middle Aged; Oxidation-Reduction; Proteins; Sarcoma | 1987 |
Tumour-host metabolic interaction and cachexia.
Topics: Amino Acids; Cachexia; Cell Division; Humans; Leucine; Models, Biological; Neoplasm Proteins; Neoplasms | 1985 |