leucine and Bone Loss, Osteoclastic

leucine has been researched along with Bone Loss, Osteoclastic in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19909 (36.00)18.7374
1990's9 (36.00)18.2507
2000's5 (20.00)29.6817
2010's2 (8.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abrahamson, M; Grubb, A; Kasprzykowski, F; Kassem, A; Lerner, UH; Lindholm, C; Strålberg, F1
Dziegiel, MH; Henriksen, K; Karsdal, MA; Kocijancic, D; Leeming, DJ; Neutzsky-Wulff, AV; Sørensen, MG1
Hayashi, M; Inomata, M; Ishibashi, H; Kawashima, S; Koshihara, Y; Saido, TC; Tsubuki, S; Yamamoto, S1
Bar-Shavit, Z; Fallon, MD; Imbimbo, C; Kahn, AJ; Malone, JD; Teitelbaum, SL1
Kahn, AJ; Malone, JD; Teitelbaum, SL1
Debari, K; Rifkin, BR; Sasaki, T; Udagawa, N1
Kakegawa, H; Katunuma, N; Kawata, T; Ohba, Y; Sumitani, K; Tagami, K1
Lee, DB; Murray, EJ; Murray, SS; Tram, KK1
Hayama, T; Kobori, T; Kondo, K; Ohba, Y; Sigeizumi, S; Sugimoto, K; Sumitani, K; Tagami, K; Tsuji, T; Woo, JT; Yamaguchi, K1
Everts, V1
Beertsen, W; Delaissé, JM; Everts, V; Korper, W1
Fujimori, K; Inui, T; Ishibashi, O; Kokubo, T; Nakajima, M; Origane, Y1
Beertsen, W; Docherty, AJ; Everts, V; Heera, S; Jansen, DC; Korper, W; Lammerse, I; Steinfort, J1
Ahern, R; Connor, JR; Dodds, RA; Drake, FH; Gowen, M; Holmes, S; Hwang, SM; James, IE; Lark, MW; Rieman, D; Thompson, SD; Veber, DF1
Inui, T; Ishibashi, O; Kokubo, T; Kumegawa, M; Kurokawa, T; Mori, Y1
Goto, T; Maeda, H; Tanaka, T1
Ikemoto, M; Kano, M; Katunuma, N; Kishi, K; Kitano, T; Nikawa, T; Shizuka, F; Towatari, T; Watanabe, C; Yoshimoto, M1
Shimizu, H1
Beertsen, W; Everts, V; Schröder, R1
Green, OC; Stern, PH; Stewart, PJ1
Krieger, NS; Stathopoulos, VM; Stern, PH1
Horton, JE; Mergenhagen, SE; Oppenheim, JJ1
Chu, LL; Cohn, DV; Hamilton, JW; Kimmel, JR; Macgregor, RR1
Holtrop, ME; Raisz, LG; Simmons, HA1
Bingham, P; Owen, M1

Reviews

2 review(s) available for leucine and Bone Loss, Osteoclastic

ArticleYear
Glucocorticoids and bone resorption.
    Advances in experimental medicine and biology, 1984, Volume: 171

    Topics: Animals; Bone Resorption; Cell Differentiation; Cells, Cultured; Glucocorticoids; Humans; Hydrocortisone; Leucine; Macrophages; Osteoclasts; Uridine

1984
A role for cell-mediated immunity in the pathogenesis of periodontal disease.
    Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Erste Abteilung Originale. Reihe A: Medizinische Mikrobiologie und Parasitologie, 1974, Volume: 227, Issue:1-4

    Topics: Animals; Antigens; Antigens, Bacterial; B-Lymphocytes; Bone Resorption; Carbon Radioisotopes; Cells, Cultured; Cytotoxicity Tests, Immunologic; Dental Plaque; Gingiva; Humans; Immunity, Cellular; Lectins; Leucine; Lymphocyte Activation; Lymphokines; Models, Biological; Periodontal Diseases; Rats; T-Lymphocytes; Veillonella

1974

Other Studies

23 other study(ies) available for leucine and Bone Loss, Osteoclastic

ArticleYear
Inhibition of lipopolysaccharide-induced osteoclast formation and bone resorption in vitro and in vivo by cysteine proteinase inhibitors.
    Journal of leukocyte biology, 2017, Volume: 101, Issue:5

    Topics: Animals; Bone Density Conservation Agents; Bone Marrow Cells; Bone Resorption; Cathepsin K; Cystatin C; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Immunologic; Gene Expression Regulation; Interleukin-6; Leucine; Lipopolysaccharides; Macrophages; Mice; NFATC Transcription Factors; Oligopeptides; Oncostatin M; Osteoclasts; Primary Cell Culture; Proto-Oncogene Proteins c-fos; RANK Ligand; Signal Transduction; Tartrate-Resistant Acid Phosphatase; Tumor Necrosis Factor-alpha

2017
Alterations in osteoclast function and phenotype induced by different inhibitors of bone resorption--implications for osteoclast quality.
    BMC musculoskeletal disorders, 2010, Jun-01, Volume: 11

    Topics: Animals; Bone Density Conservation Agents; Bone Resorption; Cattle; Cell Culture Techniques; Cell Differentiation; Cells, Cultured; Diphosphonates; Enzyme Inhibitors; Humans; Ibandronic Acid; Leucine; Macrolides; Macrophage Colony-Stimulating Factor; Monocytes; Osteoclasts; Phenotype; Protease Inhibitors; RANK Ligand

2010
Involvement of calpain in osteoclastic bone resorption.
    Journal of biochemistry, 2005, Volume: 137, Issue:3

    Topics: Actins; Aged; Bone and Bones; Bone Resorption; Calpain; Cells, Cultured; Dipeptides; Humans; Leucine; Osteoclasts; Recombinant Fusion Proteins; Talin

2005
Glucocorticoid enhancement of bone resorption by rat peritoneal macrophages in vitro.
    Endocrinology, 1981, Volume: 108, Issue:3

    Topics: Animals; Ascitic Fluid; Bone and Bones; Bone Resorption; Glucocorticoids; Hydrocortisone; In Vitro Techniques; Leucine; Macrophages; Rats; Uridine

1981
An ultrastructural evaluation of the effects of cysteine-proteinase inhibitors on osteoclastic resorptive functions.
    Calcified tissue international, 1995, Volume: 56, Issue:6

    Topics: Animals; Animals, Newborn; Bone Resorption; Cathepsins; Cells, Cultured; Collagen; Cysteine Proteinase Inhibitors; Dentin; Diazomethane; Leucine; Mice; Microscopy, Electron, Scanning; Osteoclasts; Tooth Demineralization

1995
Secretion and processing mechanisms of procathepsin L in bone resorption.
    FEBS letters, 1995, Aug-14, Volume: 370, Issue:1-2

    Topics: Animals; Blotting, Western; Bone and Bones; Bone Resorption; Calcitriol; Calcium; Cathepsin L; Cathepsins; Cells, Cultured; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dipeptides; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Enzyme Precursors; Humans; Leucine; Male; Parathyroid Hormone; Peptide Fragments; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Teriparatide; Tumor Necrosis Factor-alpha

1995
PTH-induced osteoblast contraction is mediated by cysteine proteases.
    Kidney international, 1993, Volume: 43, Issue:3

    Topics: Animals; Bone Resorption; Calpain; Cell Line; Cyclic AMP; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Leucine; Mice; Osteoblasts; Parathyroid Hormone

1993
Suppressive effect of N-(benzyloxycarbonyl)-L-phenylalanyl-L-tyrosinal on bone resorption in vitro and in vivo.
    European journal of pharmacology, 1996, Apr-04, Volume: 300, Issue:1-2

    Topics: Animals; Bone and Bones; Bone Resorption; Cathepsin L; Cathepsins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dipeptides; Endopeptidases; Female; Humans; Leucine; Mice; Ovariectomy; Rats; Rats, Sprague-Dawley

1996
Is cathepsin K truly involved in bone resorption?
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1998, Volume: 13, Issue:2

    Topics: Bone Resorption; Cathepsin K; Cathepsins; Cysteine Proteinase Inhibitors; Dipeptides; Humans; Ketones; Leucine; Osteoclasts

1998
Cysteine proteinases and matrix metalloproteinases play distinct roles in the subosteoclastic resorption zone.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1998, Volume: 13, Issue:9

    Topics: Amides; Amino Acids, Branched-Chain; Animals; Bone Matrix; Bone Resorption; Cells, Cultured; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dipeptides; Hydrogen-Ion Concentration; Leucine; Metalloendopeptidases; Mice; Morpholines; Osteoclasts; Protease Inhibitors; Skull; Time Factors

1998
Matrix metalloproteinases and lysosomal cysteine proteases in osteoclasts contribute to bone resorption through distinct modes of action.
    Biochemical and biophysical research communications, 1999, Apr-29, Volume: 258, Issue:1

    Topics: Animals; Base Sequence; Bone Resorption; Cysteine Endopeptidases; DNA Primers; Leucine; Lysosomes; Metalloendopeptidases; Osteoblasts; Phenylalanine; Protease Inhibitors; Rabbits; Reverse Transcriptase Polymerase Chain Reaction; Thiophenes

1999
Functional heterogeneity of osteoclasts: matrix metalloproteinases participate in osteoclastic resorption of calvarial bone but not in resorption of long bone.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1999, Volume: 13, Issue:10

    Topics: Amides; Animals; Bone Resorption; Cathepsins; Cattle; Collagen; Extracellular Matrix; Immunohistochemistry; In Vitro Techniques; Leucine; Metalloendopeptidases; Mice; Morpholines; Osteoclasts; Protease Inhibitors; Rabbits

1999
Human osteoclast cathepsin K is processed intracellularly prior to attachment and bone resorption.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2001, Volume: 16, Issue:3

    Topics: Biochemistry; Bone and Bones; Bone Resorption; Cathepsin K; Cathepsins; Cell Adhesion; Cysteine Proteinase Inhibitors; Giant Cell Tumor of Bone; Humans; Hydrogen-Ion Concentration; Kidney; Leucine; Linear Models; Oligopeptides; Osteoclasts; Pepstatins; Phenylmethylsulfonyl Fluoride; Protease Inhibitors; Protein Processing, Post-Translational; Substrate Specificity; Tumor Cells, Cultured

2001
Quantification of the expression levels of lysosomal cysteine proteinases in purified human osteoclastic cells by competitive RT-PCR.
    Calcified tissue international, 2001, Volume: 68, Issue:2

    Topics: Acid Phosphatase; Adult; Bone Marrow Cells; Bone Resorption; Calcitonin; Cathepsin K; Cathepsins; Cysteine Endopeptidases; DNA Primers; Dose-Response Relationship, Drug; Female; Fluorescent Antibody Technique, Indirect; Gene Expression; Giant Cell Tumor of Bone; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Isoenzymes; Leucine; Osteoblasts; Osteoclasts; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tartrate-Resistant Acid Phosphatase; Tumor Cells, Cultured

2001
A selective inhibitor of matrix metalloproteinases inhibits the migration of isolated osteoclasts by increasing the life span of podosomes.
    Journal of bone and mineral metabolism, 2002, Volume: 20, Issue:2

    Topics: Actins; Animals; Bone Resorption; Cell Movement; Cells, Cultured; Cysteine Proteinase Inhibitors; Glycine; Hydroxamic Acids; Leucine; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Molecular Structure; Osteoclasts; Protease Inhibitors; Rabbits

2002
A cysteine protease inhibitor prevents suspension-induced declines in bone weight and strength in rats.
    Journal of physiological anthropology and applied human science, 2002, Volume: 21, Issue:1

    Topics: Animals; Bone and Bones; Bone Resorption; Calcium; Cathepsin K; Cathepsins; Collagenases; Cysteine Proteinase Inhibitors; Etidronic Acid; Femur; Hydroxyproline; Leucine; Male; Organ Size; Rats; Rats, Wistar; Weightlessness

2002
Different resorption modes on living and devitalized bones by isolated osteoclasts in vitro. The effects of TIMP, E-64, and TGF-alpha.
    Dentistry in Japan, 1990, Volume: 27, Issue:1

    Topics: Animals; Bone Resorption; Cysteine Proteinase Inhibitors; Disease Models, Animal; Female; Glycoproteins; Indomethacin; Leucine; Metalloendopeptidases; Mice; Microscopy, Electron, Scanning; Osteoclasts; Prostaglandins; Rabbits; Tissue Inhibitor of Metalloproteinases; Transforming Growth Factor alpha

1990
Effects of the proteinase inhibitors leupeptin and E-64 on osteoclastic bone resorption.
    Calcified tissue international, 1988, Volume: 43, Issue:3

    Topics: Animals; Bone Resorption; Cells, Cultured; Leucine; Leupeptins; Mice; Oligopeptides; Osteoclasts; Protease Inhibitors

1988
Cyclosporine A inhibits calcemic hormone-induced bone resorption in vitro.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1986, Volume: 1, Issue:3

    Topics: Animals; Bone and Bones; Bone Resorption; Calcitriol; Culture Techniques; Cyclosporins; Dinoprostone; DNA; Leucine; Lymphokines; Parathyroid Hormone; Protein Biosynthesis; Rats; Rats, Inbred Strains; Thymidine

1986
Does amrinone inhibition of stimulated bone resorption involve Na+-Ca++ exchange?
    Circulation, 1986, Volume: 73, Issue:3 Pt 2

    Topics: Aminopyridines; Amrinone; Animals; Bone Resorption; Calcium; Cardiotonic Agents; Cycloheximide; Dactinomycin; Hydroxyurea; In Vitro Techniques; Ion Exchange; Leucine; Mice; Parathyroid Hormone; Rats; Rats, Inbred Strains; Sodium; Thymidine; Uridine

1986
Calcemic fraction-A: biosynthetic peptide precursor of parathyroid hormone.
    Proceedings of the National Academy of Sciences of the United States of America, 1972, Volume: 69, Issue:6

    Topics: Acrylamides; Amino Acids; Animals; Antibody Specificity; Bone Resorption; Calcium; Cattle; Chemical Phenomena; Chemistry; Chromatography; Chromatography, Gel; Electrophoresis; Immune Sera; Isotope Labeling; Kinetics; Leucine; Lysine; Molecular Weight; Parathyroid Glands; Parathyroid Hormone; Peptide Biosynthesis; Peptides; Sodium Dodecyl Sulfate; Time Factors; Tritium

1972
Inhibition of bone resorption by colchicine in organ culture.
    Endocrinology, 1973, Volume: 92, Issue:2

    Topics: Animals; Bone and Bones; Bone Resorption; Calcitonin; Calcium; Calcium Isotopes; Colchicine; Fetus; Leucine; Parathyroid Hormone; Radius; Rats; Thymidine; Time Factors; Tritium; Ulna; Uridine; Vitamin D

1973
Effects of PTE on bone cell metabolism in vivo.
    Calcified tissue research, 1968

    Topics: Animals; Bone Resorption; Femur; Glucosamine; Leucine; Osteoblasts; Osteocytes; Parathyroid Glands; Rabbits; RNA; Tissue Extracts; Tritium; Uridine

1968