leucine has been researched along with Angiogenesis, Pathologic in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (40.00) | 29.6817 |
| 2010's | 7 (46.67) | 24.3611 |
| 2020's | 2 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Hossain, MZ; Mohammed Alabsi, A; Mohd Bakri, M; Ramanathan, A; Syed Abdul Rahman, SN; Yahya, F | 1 |
| Chang, X; Duan, T; He, Q; Li, H; Wang, K; Yao, J | 1 |
| Ahmadieh, H; Hafezi-Moghadam, A; Ishibashi, T; Ishikawa, K; Kanavi, MR; Koga, T; Nakama, T; Nakao, S; Ohba, M; Okuno, T; Penninger, JM; Saeki, K; Sasaki, F; Sonoda, KH; Yokomizo, T; Yoshida, S | 1 |
| Chen, XQ; Li, L; Ma, C; Wang, RF; Yan, P; Yin, L; Zhao, Q | 1 |
| Adapala, RK; Cappelli, HC; Chilian, WM; Dudley, AC; Ghosh, K; Ingber, DE; Keshamouni, V; Klagsbrun, M; Meszaros, JG; Paruchuri, S; Thodeti, CK; Thoppil, RJ | 1 |
| Adapala, RK; Cappelli, HC; Dudley, AC; Gary Meszaros, J; Kondeti, V; Paruchuri, S; Thodeti, CK; Thoppil, RJ | 1 |
| Birrane, G; Cooke, VG; Eikesdal, HP; Kalluri, R; Kieran, M; Maeshima, Y; Sugimoto, H | 1 |
| Ito, S; Miyahara, R; Nagai, S; Takahashi, R; Takenaka, K; Tanaka, F; Wada, H | 1 |
| Dalrymple, SA; Elie, BT; Gocheva, V; Holsinger, LJ; Joyce, JA; Shree, T | 1 |
| Gullbo, J; Larsson, R; Nygren, P; Wickström, M | 1 |
| Cheng, YN; Cui, SX; Gao, JJ; Gao, ZH; Qu, XJ; Tang, W; Xu, WF; Xue, X | 1 |
| Aozuka, Y; Koizumi, K; Saiki, I; Saitoh, Y; Sakurai, H; Ueda, Y | 1 |
| Klibanov, AL; Lu, E; Modzelewski, RA; Villanueva, FS; Wagner, WR; Weller, GE; Wong, MK | 1 |
| Fan, H; Ge, R; Jois, S; Kini, RM; Subramanian, V; Sulochana, KN; Sun, F | 1 |
| Carmona, AK; Juliano, L; Juliano, MA; Monteiro, HP; Oliveira, V; Paschoalin, T; Rodrigues, EG; Travassos, LR | 1 |
2 review(s) available for leucine and Angiogenesis, Pathologic
| Article | Year |
|---|---|
Aminopeptidase N (CD13) as a target for cancer chemotherapy.
Topics: CD13 Antigens; Cell Proliferation; Clinical Trials as Topic; Glycine; Humans; Hydroxamic Acids; Leucine; Neoplasm Invasiveness; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Prognosis; Protease Inhibitors | 2011 |
LYP, a bestatin dimethylaminoethyl ester, inhibited cancer angiogenesis both in vitro and in vivo.
Topics: Angiogenesis Inhibitors; Animals; CD13 Antigens; Cell Membrane; Endothelium, Vascular; Esters; Fibroblast Growth Factor 2; Humans; Leucine; Mice; Neoplasm Transplantation; Neoplasms; Neovascularization, Pathologic; Transforming Growth Factor alpha; Umbilical Veins; Vascular Endothelial Growth Factor A | 2011 |
13 other study(ies) available for leucine and Angiogenesis, Pathologic
| Article | Year |
|---|---|
Combination Treatment of TRPV4 Agonist with Cisplatin Promotes Vessel Normalization in an Animal Model of Oral Squamous Cell Carcinoma.
Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cisplatin; Disease Models, Animal; Head and Neck Neoplasms; Leucine; Mouth Neoplasms; Neovascularization, Pathologic; Nitroquinolines; Oxides; Rats; Rats, Sprague-Dawley; Receptor, TIE-2; Squamous Cell Carcinoma of Head and Neck; Sulfonamides; TRPV Cation Channels | 2022 |
Exosome enriched leucine-rich alpha-2-glycoprotein-1 and extracellular matrix protein 1 proteins induce abnormal placental angiogenesis in pregnant mice.
Topics: Animals; Diabetes, Gestational; Endothelial Cells; Exosomes; Extracellular Matrix Proteins; Female; Glycoproteins; Humans; Leucine; Mice; Neovascularization, Pathologic; Placenta; Pregnancy | 2023 |
Leukotriene B4 promotes neovascularization and macrophage recruitment in murine wet-type AMD models.
Topics: Animals; Benzopyrans; Carboxylic Acids; Choroidal Neovascularization; Disease Models, Animal; Eye; Eye Injuries; Hydroxyurea; Indoles; Lasers; Leucine; Leukotriene B4; Macrophages; Macular Degeneration; Male; Mice; Mice, Knockout; Neovascularization, Pathologic; Receptors, Leukotriene B4; Signal Transduction | 2018 |
Validation study of ¹³¹I-RRL: assessment of biodistribution, SPECT imaging and radiation dosimetry in mice.
Topics: Animals; Arginine; Humans; Leucine; Melanoma, Experimental; Mice; Molecular Probes; Neovascularization, Pathologic; Peptides; Radiation Dosage; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 2013 |
Activation of mechanosensitive ion channel TRPV4 normalizes tumor vasculature and improves cancer therapy.
Topics: Animals; Calcium Signaling; Carcinoma, Lewis Lung; Cell Line, Tumor; Cell Proliferation; Cisplatin; Endothelium, Vascular; Gene Expression Regulation, Neoplastic; Humans; Leucine; Mice; Neovascularization, Pathologic; Sulfonamides; TRPV Cation Channels; Vascular Endothelial Growth Factor A | 2016 |
TRPV4 channel activation selectively inhibits tumor endothelial cell proliferation.
Topics: Animals; Antineoplastic Agents; Cell Proliferation; Endothelial Cells; Leucine; MAP Kinase Signaling System; Mice; Neoplasms; Neovascularization, Pathologic; Sulfonamides; TRPV Cation Channels; Up-Regulation | 2015 |
Identification of amino acids essential for the antiangiogenic activity of tumstatin and its use in combination antitumor activity.
Topics: Amino Acid Substitution; Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Autoantigens; Bevacizumab; Carcinoma, Renal Cell; Cell Proliferation; Cells, Cultured; Collagen Type IV; Endothelial Cells; Humans; Integrin alphaVbeta3; Kidney Neoplasms; Leucine; Mice; Mice, Inbred C57BL; Mutagenesis, Site-Directed; Neoplasm Transplantation; Neovascularization, Pathologic; Protein Conformation; Valine; Xenograft Model Antitumor Assays | 2008 |
Stromal aminopeptidase N expression: correlation with angiogenesis in non-small-cell lung cancer.
Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; CD13 Antigens; Chemotherapy, Adjuvant; Female; Fibroblasts; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Leucine; Lung Neoplasms; Lymph Node Excision; Male; Microvessels; Middle Aged; Neovascularization, Pathologic; Pneumonectomy; Retrospective Studies; Time Factors; Treatment Outcome | 2009 |
Identification and pre-clinical testing of a reversible cathepsin protease inhibitor reveals anti-tumor efficacy in a pancreatic cancer model.
Topics: Animals; Antineoplastic Agents; Apoptosis; Biological Availability; Cathepsins; Cell Proliferation; Cyclopropanes; Disease Models, Animal; Drug Design; Drug Evaluation, Preclinical; Humans; Hydrocarbons, Fluorinated; Leucine; Mice; Neoplasm Invasiveness; Neovascularization, Pathologic; Pancreatic Neoplasms; Protease Inhibitors; Sulfones; Tumor Burden | 2010 |
Anti-tumor angiogenesis effect of aminopeptidase inhibitor bestatin against B16-BL6 melanoma cells orthotopically implanted into syngeneic mice.
Topics: Animals; Endothelial Cells; Female; Leucine; Melanoma; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Neovascularization, Pathologic; Protease Inhibitors; Skin Neoplasms; Transplantation, Heterologous; Umbilical Veins | 2004 |
Ultrasonic imaging of tumor angiogenesis using contrast microbubbles targeted via the tumor-binding peptide arginine-arginine-leucine.
Topics: Animals; Arginine; Carcinoma, Squamous Cell; Echocardiography; Endothelium, Vascular; Fluorescein; Humans; Leucine; Male; Mice; Mice, Inbred C3H; Mice, Nude; Microbubbles; Myocardium; Neoplasm Transplantation; Neovascularization, Pathologic; NIH 3T3 Cells; Oligopeptides; Prostatic Neoplasms; Transplantation, Heterologous | 2005 |
Peptides derived from human decorin leucine-rich repeat 5 inhibit angiogenesis.
Topics: Actins; Amino Acid Sequence; Angiogenesis Inhibitors; Animals; Apoptosis; Blotting, Western; Caspases; Cell Adhesion; Cell Movement; Cell Proliferation; Cells, Cultured; Circular Dichroism; Collagen; Decorin; Dose-Response Relationship, Drug; Drug Combinations; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Extracellular Matrix Proteins; Fibroblast Growth Factor 2; Fibronectins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; Humans; Immunoprecipitation; Kinetics; Laminin; Leucine; Molecular Sequence Data; Neovascularization, Pathologic; Peptides; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Proteoglycans; Recombinant Proteins; Sequence Homology, Amino Acid; Umbilical Veins; Vascular Endothelial Growth Factor A | 2005 |
Characterization of thimet oligopeptidase and neurolysin activities in B16F10-Nex2 tumor cells and their involvement in angiogenesis and tumor growth.
Topics: Angiogenic Proteins; Animals; Antineoplastic Agents; Bradykinin; Cell Extracts; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Cloning, Molecular; Coculture Techniques; Collagen; Culture Media, Conditioned; Dipeptides; Dose-Response Relationship, Drug; Drug Combinations; Endothelial Cells; Female; Hydrolysis; Laminin; Leucine; Melanoma, Experimental; Metalloendopeptidases; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; Neurotensin; Nitric Oxide; Nitric Oxide Donors; Oligopeptides; Peptides; Phenanthrolines; Protease Inhibitors; Proteoglycans; S-Nitroso-N-Acetylpenicillamine; Substrate Specificity | 2007 |