leucine and Anemia, Diamond-Blackfan

leucine has been researched along with Anemia, Diamond-Blackfan in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's6 (75.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Alhushki, W; Atsidaftos, E; Bernstein, J; Farrar, JE; Glader, B; Gruner, B; Hartung, H; Knoll, C; Lababidi, ML; Lipton, JM; Loew, T; Muir, E; Nalepa, G; Narla, A; Panigrahi, AR; Rogers, ZR; Sieff, CA; Vlachos, A; Walkovich, K1
Chakraborty, A; Kenmochi, N; Uechi, T; Yadav, GV1
Ear, J; Lin, S; Morimoto, K; Yang, Z; Zhang, B; Zhang, Y1
Abayasekara, N; Berliner, N; Ebert, BL; Hurst, SN; Khanna-Gupta, A; Look, AT; Narla, A; Payne, EM; Raiser, DM1
Berliner, N; Ebert, BL; Khanna-Gupta, A; Levine, M; Look, AT; Narla, A; Paw, BH; Payne, EM; Sun, H; Virgilio, M1
Bryder, D; Debnath, S; Flygare, J; Jaako, P; Karlsson, S; Olsson, K1
Boultwood, J; Pellagatti, A; Vuppusetty, C; Wainscoat, JS; Yip, BH1
Adam, T; Cmejla, R; Cmejlova, J; Hak, J; Pospisilova, D1

Reviews

1 review(s) available for leucine and Anemia, Diamond-Blackfan

ArticleYear
Activation of the mTOR pathway by the amino acid (L)-leucine in the 5q- syndrome and other ribosomopathies.
    Advances in biological regulation, 2013, Volume: 53, Issue:1

    Topics: Anemia, Diamond-Blackfan; Anemia, Macrocytic; Animals; Chromosome Deletion; Chromosomes, Human, Pair 5; Erythroblasts; Gene Expression Regulation; Haploinsufficiency; Humans; Leucine; Protein Biosynthesis; Ribosomal Proteins; Ribosomes; Signal Transduction; TOR Serine-Threonine Kinases

2013

Trials

1 trial(s) available for leucine and Anemia, Diamond-Blackfan

ArticleYear
L-leucine improves anemia and growth in patients with transfusion-dependent Diamond-Blackfan anemia: Results from a multicenter pilot phase I/II study from the Diamond-Blackfan Anemia Registry.
    Pediatric blood & cancer, 2020, Volume: 67, Issue:12

    Topics: Adolescent; Adult; Anemia, Diamond-Blackfan; Blood Transfusion; Child; Child, Preschool; Combined Modality Therapy; Feasibility Studies; Female; Follow-Up Studies; Humans; Leucine; Male; Middle Aged; Pilot Projects; Prognosis; Young Adult

2020

Other Studies

6 other study(ies) available for leucine and Anemia, Diamond-Blackfan

ArticleYear
Ribosomal protein deficiency causes Tp53-independent erythropoiesis failure in zebrafish.
    The international journal of biochemistry & cell biology, 2014, Volume: 49

    Topics: Anemia, Diamond-Blackfan; Animals; Arginine; Embryo, Nonmammalian; Erythrocyte Count; Erythroid Cells; Erythropoiesis; Gene Expression Regulation, Developmental; Gene Knockdown Techniques; Humans; Leucine; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Proteins; Ribosomes; Sirolimus; Tumor Suppressor Protein p53; Zebrafish; Zebrafish Proteins

2014
Defects of protein production in erythroid cells revealed in a zebrafish Diamond-Blackfan anemia model for mutation in RPS19.
    Cell death & disease, 2014, Jul-24, Volume: 5

    Topics: Anemia, Diamond-Blackfan; Animals; Disease Models, Animal; Erythroid Cells; Humans; Leucine; Mutation; Ribosomal Proteins; Zebrafish; Zebrafish Proteins

2014
L-Leucine improves the anaemia in models of Diamond Blackfan anaemia and the 5q- syndrome in a TP53-independent way.
    British journal of haematology, 2014, Volume: 167, Issue:4

    Topics: Anemia, Diamond-Blackfan; Anemia, Macrocytic; Animals; Chromosome Deletion; Chromosomes, Human, Pair 5; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; Humans; Leucine; Ribosomal Proteins; Tumor Suppressor Protein p53; Zebrafish Proteins

2014
L-Leucine improves the anemia and developmental defects associated with Diamond-Blackfan anemia and del(5q) MDS by activating the mTOR pathway.
    Blood, 2012, Sep-13, Volume: 120, Issue:11

    Topics: Anemia, Diamond-Blackfan; Anemia, Macrocytic; Animals; Animals, Genetically Modified; Cells, Cultured; Chromosome Deletion; Chromosomes, Human, Pair 5; Disease Models, Animal; Embryo, Nonmammalian; Embryonic Development; Hematinics; Hematopoiesis; Hematopoietic Stem Cells; Humans; Leucine; Myelodysplastic Syndromes; Ribosomal Proteins; RNA, Small Interfering; Signal Transduction; TOR Serine-Threonine Kinases; Up-Regulation; Zebrafish; Zebrafish Proteins

2012
Dietary L-leucine improves the anemia in a mouse model for Diamond-Blackfan anemia.
    Blood, 2012, Sep-13, Volume: 120, Issue:11

    Topics: Anemia, Diamond-Blackfan; Animals; Bone Marrow Cells; Dietary Supplements; Disease Models, Animal; Down-Regulation; Erythrocyte Count; Gene Knockdown Techniques; Hematinics; Hematopoiesis; Hematopoietic Stem Cells; Hemoglobins; Leucine; Mice; Mice, Transgenic; Molecular Targeted Therapy; Ribosomal Proteins; RNA Interference; RNA, Messenger; RNA, Small Interfering; Tumor Suppressor Protein p53; Up-Regulation

2012
Successful treatment of a Diamond-Blackfan anemia patient with amino acid leucine.
    Haematologica, 2007, Volume: 92, Issue:5

    Topics: Amino Acids, Essential; Anemia, Diamond-Blackfan; Child; Female; Humans; Leucine; Treatment Outcome

2007