leucamide-a and Influenza--Human

leucamide-a has been researched along with Influenza--Human* in 1 studies

Other Studies

1 other study(ies) available for leucamide-a and Influenza--Human

Article	Year
Synthesis and antiviral activity of conformational analogues of leucamide A. Molecules (Basel, Switzerland), 2012, Dec-07, Volume: 17, Issue:12 In order to study the effect of heterocyclic core conformational state of leucamide A on its anti-influenza virus A activity, five conformational analogues were prepared by replacing the Pro-Leu dipeptide in the molecule with various amino acids. The amino acids used were of 2 to 6 carbons. The results showed that these replacements not only changed the conformational relationship between the 4,2-bisheterocycle tandem pair and the third heterocycle, but also had dramatic effect on its activity against influenza virus A. Topics: Antiviral Agents; Humans; Influenza A virus; Influenza, Human; Molecular Conformation; Molecular Structure; Peptides, Cyclic; Structure-Activity Relationship	2012

Article

Year

Synthesis and antiviral activity of conformational analogues of leucamide A.

Molecules (Basel, Switzerland), 2012, Dec-07, Volume: 17, Issue:12

In order to study the effect of heterocyclic core conformational state of leucamide A on its anti-influenza virus A activity, five conformational analogues were prepared by replacing the Pro-Leu dipeptide in the molecule with various amino acids. The amino acids used were of 2 to 6 carbons. The results showed that these replacements not only changed the conformational relationship between the 4,2-bisheterocycle tandem pair and the third heterocycle, but also had dramatic effect on its activity against influenza virus A.

Topics: Antiviral Agents; Humans; Influenza A virus; Influenza, Human; Molecular Conformation; Molecular Structure; Peptides, Cyclic; Structure-Activity Relationship

2012