Page last updated: 2024-10-30

letrozole and Weight Gain

letrozole has been researched along with Weight Gain in 6 studies

Weight Gain: Increase in BODY WEIGHT over existing weight.

Research Excerpts

ExcerptRelevanceReference
"Children of women with polycystic ovary syndrome who conceived with letrozole (LTZ) or clomiphene (CC) in the PPCOS II study or women with unexplained infertility (AMIGOS study) who conceived with LTZ, CC, or gonadotropin (GN)."7.96Pregnancy registry: three-year follow-up of children conceived from letrozole, clomiphene, or gonadotropins. ( Alvero, R; Baker, V; Barnhart, KT; Casson, P; Cedars, MI; Christman, GM; Coutifaris, C; Coward, RM; Diamond, MP; Dodson, WC; Eisenberg, E; Estes, SJ; Hansen, KR; Huang, H; Krawetz, SA; Kunselman, A; Legro, RS; Robinson, R; Rosen, RM; Santoro, N; Schlaff, WD; Stetter, C; Trussell, JC; Usadi, R; Zhang, H, 2020)
"The present study examines the effect of soy isoflavones on letrozole-induced polycystic ovary syndrome (PCOS) rat model."7.85Soy isoflavones exert beneficial effects on letrozole-induced rat polycystic ovary syndrome (PCOS) model through anti-androgenic mechanism. ( Balaji, B; M, SS; Rajan, RK, 2017)
"We also investigated whether hyperinsulinemia occurs secondary to weight gain and insulin resistance in this model or if it can occur independently."5.46Hyperandrogenemia Induced by Letrozole Treatment of Pubertal Female Mice Results in Hyperinsulinemia Prior to Weight Gain and Insulin Resistance. ( Anvar, AR; Hernández-Carretero, A; Rivera, AJ; Skarra, DV; Thackray, VG, 2017)
"Children of women with polycystic ovary syndrome who conceived with letrozole (LTZ) or clomiphene (CC) in the PPCOS II study or women with unexplained infertility (AMIGOS study) who conceived with LTZ, CC, or gonadotropin (GN)."3.96Pregnancy registry: three-year follow-up of children conceived from letrozole, clomiphene, or gonadotropins. ( Alvero, R; Baker, V; Barnhart, KT; Casson, P; Cedars, MI; Christman, GM; Coutifaris, C; Coward, RM; Diamond, MP; Dodson, WC; Eisenberg, E; Estes, SJ; Hansen, KR; Huang, H; Krawetz, SA; Kunselman, A; Legro, RS; Robinson, R; Rosen, RM; Santoro, N; Schlaff, WD; Stetter, C; Trussell, JC; Usadi, R; Zhang, H, 2020)
" In addition, the minimal weight gain and lack of insulin resistance in adult female mice after letrozole treatment indicates that this model may be useful for investigating the effects of hyperandrogenemia on the hypothalamic-pituitary-gonadal axis and the periphery without the influence of substantial metabolic dysregulation."3.91Letrozole treatment of adult female mice results in a similar reproductive phenotype but distinct changes in metabolism and the gut microbiome compared to pubertal mice. ( Anvar, AR; Ho, BS; Kelley, ST; Sau, L; Skarra, DV; Thackray, VG; Torres, PJ, 2019)
"The present study examines the effect of soy isoflavones on letrozole-induced polycystic ovary syndrome (PCOS) rat model."3.85Soy isoflavones exert beneficial effects on letrozole-induced rat polycystic ovary syndrome (PCOS) model through anti-androgenic mechanism. ( Balaji, B; M, SS; Rajan, RK, 2017)
"We also investigated whether hyperinsulinemia occurs secondary to weight gain and insulin resistance in this model or if it can occur independently."1.46Hyperandrogenemia Induced by Letrozole Treatment of Pubertal Female Mice Results in Hyperinsulinemia Prior to Weight Gain and Insulin Resistance. ( Anvar, AR; Hernández-Carretero, A; Rivera, AJ; Skarra, DV; Thackray, VG, 2017)
"Letrozole was administered to the animals in the second and third groups by daily oral gavage at 0."1.35Effects of letrozole on hippocampal and cortical catecholaminergic neurotransmitter levels, neural cell adhesion molecule expression and spatial learning and memory in female rats. ( Alcin, E; Aydin, M; Nedzvetsky, VS; Sahin, Z; Tuzcu, M; Yilmaz, B, 2008)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's4 (66.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Legro, RS1
Diamond, MP1
Coutifaris, C1
Schlaff, WD1
Alvero, R1
Casson, P1
Christman, GM1
Rosen, RM1
Cedars, MI1
Hansen, KR1
Robinson, R1
Baker, V1
Usadi, R1
Dodson, WC1
Estes, SJ1
Kunselman, A1
Stetter, C1
Barnhart, KT1
Coward, RM1
Trussell, JC1
Krawetz, SA1
Santoro, N1
Huang, H1
Zhang, H1
Eisenberg, E1
Skarra, DV2
Hernández-Carretero, A1
Rivera, AJ1
Anvar, AR2
Thackray, VG2
Torres, PJ1
Ho, BS1
Sau, L1
Kelley, ST1
Spritzer, PM1
Motta, AB1
Sir-Petermann, T1
Diamanti-Kandarakis, E1
Rajan, RK1
M, SS1
Balaji, B1
Aydin, M1
Yilmaz, B1
Alcin, E1
Nedzvetsky, VS1
Sahin, Z1
Tuzcu, M1

Reviews

1 review available for letrozole and Weight Gain

ArticleYear
Novel strategies in the management of polycystic ovary syndrome.
    Minerva endocrinologica, 2015, Volume: 40, Issue:3

    Topics: Adult; Clomiphene; Contraceptives, Oral, Combined; Female; Fertility Agents, Female; Fertilization i

2015

Other Studies

5 other studies available for letrozole and Weight Gain

ArticleYear
Pregnancy registry: three-year follow-up of children conceived from letrozole, clomiphene, or gonadotropins.
    Fertility and sterility, 2020, Volume: 113, Issue:5

    Topics: Adult; Age Factors; Child Behavior; Child Development; Child, Preschool; Clomiphene; Cognition; Fema

2020
Hyperandrogenemia Induced by Letrozole Treatment of Pubertal Female Mice Results in Hyperinsulinemia Prior to Weight Gain and Insulin Resistance.
    Endocrinology, 2017, 09-01, Volume: 158, Issue:9

    Topics: Animals; Eating; Energy Metabolism; Female; Glucose; Hyperandrogenism; Hyperinsulinism; Insulin Resi

2017
Letrozole treatment of adult female mice results in a similar reproductive phenotype but distinct changes in metabolism and the gut microbiome compared to pubertal mice.
    BMC microbiology, 2019, 03-12, Volume: 19, Issue:1

    Topics: Age Factors; Animals; Aromatase Inhibitors; Disease Models, Animal; Female; Gastrointestinal Microbi

2019
Soy isoflavones exert beneficial effects on letrozole-induced rat polycystic ovary syndrome (PCOS) model through anti-androgenic mechanism.
    Pharmaceutical biology, 2017, Volume: 55, Issue:1

    Topics: 17-Hydroxysteroid Dehydrogenases; 3-Hydroxysteroid Dehydrogenases; Androgen Antagonists; Animals; An

2017
Effects of letrozole on hippocampal and cortical catecholaminergic neurotransmitter levels, neural cell adhesion molecule expression and spatial learning and memory in female rats.
    Neuroscience, 2008, Jan-02, Volume: 151, Issue:1

    Topics: Animals; Aromatase Inhibitors; Blotting, Western; Catecholamines; Cerebral Cortex; Chromatography, H

2008