Page last updated: 2024-10-30

letrozole and Uterine Neoplasms

letrozole has been researched along with Uterine Neoplasms in 20 studies

Uterine Neoplasms: Tumors or cancer of the UTERUS.

Research Excerpts

ExcerptRelevanceReference
" Here we report a case of lobular breast cancer metastasizing to a leiomyoma in a patient using letrozole."7.77Lobular carcinoma of the breast metastasizing to leiomyoma in a patient under letrozole treatment. ( Aydinli, K; Basgul, AY; Calay, Z; Dünder, I; Güdücü, N; Işçi, H, 2011)
"Letrozole was found to be well tolerated."6.79Phase 2 trial of aromatase inhibition with letrozole in patients with uterine leiomyosarcomas expressing estrogen and/or progesterone receptors. ( Butrynski, JE; Demetri, GD; Feng, Y; George, S; Harmon, D; Krasner, C; Manola, J; Morgan, JA; Nucci, MR; Penson, RT; Quek, R; Ramaiya, N; Wagner, AJ, 2014)
"Uterine leiomyomas are the most common benign tumours of the female genital tract, often necessitating hysterectomy."6.73Treatment of symptomatic uterine leiomyoma with letrozole. ( Celik, H; Gurates, B; Kilic, G; Kumru, S; Parmaksiz, C; Simsek, M, 2008)
"Slow disease progression after a poor response to adriamycin and hormone receptor positivity led to the start of letrozole."5.91Long-term effect of letrozole on metastatic uterine smooth muscle tumors of uncertain malignant potential: A case report. ( Hayashi, T; Kato, S; Kido, H; Naito, T; Praben, P; Takagi, T; Terao, Y, 2023)
"Condensation letrozole in combination with cabergoline in the management of uterine fibroids."5.24Comparing the effect of aromatase inhibitor (letrozole) + cabergoline (Dostinex) and letrozole alone on uterine myoma regression,a randomized clinical trial. ( Gharabaghi, PM; Mobasseri, M; Ouladsahebmadarek, E; Rahmani, V; Sayyah-Melli, M, 2017)
" Here we report a case of lobular breast cancer metastasizing to a leiomyoma in a patient using letrozole."3.77Lobular carcinoma of the breast metastasizing to leiomyoma in a patient under letrozole treatment. ( Aydinli, K; Basgul, AY; Calay, Z; Dünder, I; Güdücü, N; Işçi, H, 2011)
"Letrozole was found to be well tolerated."2.79Phase 2 trial of aromatase inhibition with letrozole in patients with uterine leiomyosarcomas expressing estrogen and/or progesterone receptors. ( Butrynski, JE; Demetri, GD; Feng, Y; George, S; Harmon, D; Krasner, C; Manola, J; Morgan, JA; Nucci, MR; Penson, RT; Quek, R; Ramaiya, N; Wagner, AJ, 2014)
"The quality of the myometrial scar, defined by ultrasound evaluation, was similar in the two study groups both at one-week (p=0."2.79Preoperative treatment with letrozole in patients undergoing laparoscopic myomectomy of large uterine myomas: a prospective non-randomized study. ( Ferrero, S; Leone Roberti Maggiore, U; Scala, C; Venturini, PL, 2014)
"Uterine leiomyomas are the most common benign tumours of the female genital tract, often necessitating hysterectomy."2.73Treatment of symptomatic uterine leiomyoma with letrozole. ( Celik, H; Gurates, B; Kilic, G; Kumru, S; Parmaksiz, C; Simsek, M, 2008)
"Uterine fibroids, also called uterine leiomyomas or myomas, are the most common benign tumours in women of reproductive age."2.49Aromatase inhibitors for uterine fibroids. ( Lu, D; Navaratnam, K; Shi, G; Song, H, 2013)
"Slow disease progression after a poor response to adriamycin and hormone receptor positivity led to the start of letrozole."1.91Long-term effect of letrozole on metastatic uterine smooth muscle tumors of uncertain malignant potential: A case report. ( Hayashi, T; Kato, S; Kido, H; Naito, T; Praben, P; Takagi, T; Terao, Y, 2023)
"Intra- and postoperative complications, postoperative pain, and patient satisfaction were similar in the four study groups."1.42Three-month treatment with triptorelin, letrozole and ulipristal acetate before hysteroscopic resection of uterine myomas: prospective comparative pilot study. ( Bizzarri, N; Ferrero, S; Ghirardi, V; Remorgida, V; Venturini, PL, 2015)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (35.00)29.6817
2010's12 (60.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Praben, P1
Kido, H1
Terao, Y1
Takagi, T1
Hayashi, T1
Naito, T1
Kato, S1
Martin-Romano, P1
Jurado, M1
Idoate, MA1
Arbea, L1
Hernandez-Lizoain, JL1
Cano, D1
Paramo, JA1
Martin-Algarra, S1
Duhan, N1
Madaan, S1
Sen, J1
Song, H1
Lu, D1
Navaratnam, K1
Shi, G1
George, S2
Feng, Y1
Manola, J1
Nucci, MR2
Butrynski, JE1
Morgan, JA1
Ramaiya, N1
Quek, R1
Penson, RT1
Wagner, AJ1
Harmon, D1
Demetri, GD1
Krasner, C1
Serrano, C1
Tirumani, SH1
Raut, CP1
Leone Roberti Maggiore, U1
Scala, C1
Venturini, PL3
Ferrero, S3
Bizzarri, N1
Ghirardi, V1
Remorgida, V2
Sayyah-Melli, M1
Mobasseri, M1
Gharabaghi, PM1
Ouladsahebmadarek, E1
Rahmani, V1
Gurates, B1
Parmaksiz, C1
Kilic, G1
Celik, H1
Kumru, S1
Simsek, M1
Parsanezhad, ME1
Azmoon, M1
Alborzi, S1
Rajaeefard, A1
Zarei, A1
Kazerooni, T1
Frank, V1
Schmidt, EH1
Işçi, H1
Güdücü, N1
Basgul, AY1
Aydinli, K1
Calay, Z1
Dünder, I1
Komeda, S1
Furukawa, N1
Kasai, T1
Washida, A1
Kobayashi, H1
Pink, D1
Lindner, T1
Mrozek, A1
Kretzschmar, A1
Thuss-Patience, PC1
Dörken, B1
Reichardt, P1
Bréchot, JM1
Kamboucher, M1
Brauner, M1
Destable, MD1
Duperron, F1
Morère, JF1
Biri, A1
Korucuoglu, U1
Zumrutbas, N1
Tiras, B1
Guner, H1
Thiery-Vuillemin, A1
Chaigneau, L1
Meaux-Ruault, N1
Villanueva, C1
N'guyen, T1
Maurina, T1
Stein, U1
Lorgis, V1
Demarchi, M1
Pivot, X1
Bershteĭn, LM1
Maksimov, SIa1
Gershfel'd, ED1
Gamaiunova, VB1
Tsyrlina, EV1
Meshkova, IE1
Kovalenko, IG1
Larionov, AA1
Kovalevskiĭ, AIu1
Vasil'ev, DA1
Mor, G1
Eliza, M1
Song, J1
Wiita, B1
Chen, S1
Naftolin, F1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Influence of the Aromatase Inhibitor Anastrozole and GnRH Analog Goserelin Acetate as Preoperative Treatment of Vaginal Surgical Treatment of Uterine Leiomyoma: Analysis of Intra and Immediate/Late Postoperative Patterns[NCT01280045]5 participants (Actual)Interventional2011-01-31Terminated (stopped due to No grant was received then we stopped the recruitment)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for letrozole and Uterine Neoplasms

ArticleYear
Aromatase inhibitors for uterine fibroids.
    The Cochrane database of systematic reviews, 2013, Oct-23, Issue:10

    Topics: Antineoplastic Agents; Aromatase Inhibitors; Female; Hot Flashes; Humans; Leiomyoma; Letrozole; Nitr

2013
Aromatase inhibitors for uterine fibroids.
    The Cochrane database of systematic reviews, 2013, Oct-23, Issue:10

    Topics: Antineoplastic Agents; Aromatase Inhibitors; Female; Hot Flashes; Humans; Leiomyoma; Letrozole; Nitr

2013

Trials

5 trials available for letrozole and Uterine Neoplasms

ArticleYear
Phase 2 trial of aromatase inhibition with letrozole in patients with uterine leiomyosarcomas expressing estrogen and/or progesterone receptors.
    Cancer, 2014, Mar-01, Volume: 120, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Aromatase Inhibitors; Disease-Free Survival; Drug Administration

2014
Phase 2 trial of aromatase inhibition with letrozole in patients with uterine leiomyosarcomas expressing estrogen and/or progesterone receptors.
    Cancer, 2014, Mar-01, Volume: 120, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Aromatase Inhibitors; Disease-Free Survival; Drug Administration

2014
Preoperative treatment with letrozole in patients undergoing laparoscopic myomectomy of large uterine myomas: a prospective non-randomized study.
    European journal of obstetrics, gynecology, and reproductive biology, 2014, Volume: 181

    Topics: Adult; Antineoplastic Agents; Blood Loss, Surgical; Chemotherapy, Adjuvant; Cicatrix; Contraceptives

2014
Preoperative treatment with letrozole in patients undergoing laparoscopic myomectomy of large uterine myomas: a prospective non-randomized study.
    European journal of obstetrics, gynecology, and reproductive biology, 2014, Volume: 181

    Topics: Adult; Antineoplastic Agents; Blood Loss, Surgical; Chemotherapy, Adjuvant; Cicatrix; Contraceptives

2014
Comparing the effect of aromatase inhibitor (letrozole) + cabergoline (Dostinex) and letrozole alone on uterine myoma regression,a randomized clinical trial.
    European journal of obstetrics, gynecology, and reproductive biology, 2017, Volume: 210

    Topics: Adult; Antineoplastic Agents; Aromatase Inhibitors; Cabergoline; Drug Therapy, Combination; Ergoline

2017
Comparing the effect of aromatase inhibitor (letrozole) + cabergoline (Dostinex) and letrozole alone on uterine myoma regression,a randomized clinical trial.
    European journal of obstetrics, gynecology, and reproductive biology, 2017, Volume: 210

    Topics: Adult; Antineoplastic Agents; Aromatase Inhibitors; Cabergoline; Drug Therapy, Combination; Ergoline

2017
Treatment of symptomatic uterine leiomyoma with letrozole.
    Reproductive biomedicine online, 2008, Volume: 17, Issue:4

    Topics: Adult; Antineoplastic Agents; Aromatase Inhibitors; Bone and Bones; Bone Density; Female; Follicle S

2008
Treatment of symptomatic uterine leiomyoma with letrozole.
    Reproductive biomedicine online, 2008, Volume: 17, Issue:4

    Topics: Adult; Antineoplastic Agents; Aromatase Inhibitors; Bone and Bones; Bone Density; Female; Follicle S

2008
A randomized, controlled clinical trial comparing the effects of aromatase inhibitor (letrozole) and gonadotropin-releasing hormone agonist (triptorelin) on uterine leiomyoma volume and hormonal status.
    Fertility and sterility, 2010, Volume: 93, Issue:1

    Topics: Adult; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Estradiol; Female; Follicle Stimulatin

2010
A randomized, controlled clinical trial comparing the effects of aromatase inhibitor (letrozole) and gonadotropin-releasing hormone agonist (triptorelin) on uterine leiomyoma volume and hormonal status.
    Fertility and sterility, 2010, Volume: 93, Issue:1

    Topics: Adult; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Estradiol; Female; Follicle Stimulatin

2010

Other Studies

14 other studies available for letrozole and Uterine Neoplasms

ArticleYear
Long-term effect of letrozole on metastatic uterine smooth muscle tumors of uncertain malignant potential: A case report.
    The journal of obstetrics and gynaecology research, 2023, Volume: 49, Issue:11

    Topics: Disease Progression; Doxorubicin; Female; Humans; Letrozole; Lung Neoplasms; Middle Aged; Smooth Mus

2023
Long-term effect of letrozole on metastatic uterine smooth muscle tumors of uncertain malignant potential: A case report.
    The journal of obstetrics and gynaecology research, 2023, Volume: 49, Issue:11

    Topics: Disease Progression; Doxorubicin; Female; Humans; Letrozole; Lung Neoplasms; Middle Aged; Smooth Mus

2023
Durable complete remission with aromatase inhibitor therapy in a patient with metastatic uterine carcinosarcoma with poor performance status and coagulation disorders: a case report.
    Journal of medical case reports, 2017, Apr-19, Volume: 11, Issue:1

    Topics: Aromatase Inhibitors; Blood Coagulation Disorders; Bone Neoplasms; Carcinosarcoma; Female; Humans; L

2017
Durable complete remission with aromatase inhibitor therapy in a patient with metastatic uterine carcinosarcoma with poor performance status and coagulation disorders: a case report.
    Journal of medical case reports, 2017, Apr-19, Volume: 11, Issue:1

    Topics: Aromatase Inhibitors; Blood Coagulation Disorders; Bone Neoplasms; Carcinosarcoma; Female; Humans; L

2017
Role of the aromatase inhibitor letrozole in the management of uterine leiomyomas in premenopausal women.
    European journal of obstetrics, gynecology, and reproductive biology, 2013, Volume: 171, Issue:2

    Topics: Adult; Aromatase Inhibitors; Female; Humans; Leiomyoma; Letrozole; Middle Aged; Nitriles; Premenopau

2013
Role of the aromatase inhibitor letrozole in the management of uterine leiomyomas in premenopausal women.
    European journal of obstetrics, gynecology, and reproductive biology, 2013, Volume: 171, Issue:2

    Topics: Adult; Aromatase Inhibitors; Female; Humans; Leiomyoma; Letrozole; Middle Aged; Nitriles; Premenopau

2013
Hormone dependency in metastatic low-grade leiomyosarcoma following uterine smooth muscle tumour of uncertain malignant potential.
    BMJ case reports, 2014, Mar-27, Volume: 2014

    Topics: Adult; Aromatase Inhibitors; Estrogen Replacement Therapy; Estrogens; Female; Humans; Hysterectomy;

2014
Hormone dependency in metastatic low-grade leiomyosarcoma following uterine smooth muscle tumour of uncertain malignant potential.
    BMJ case reports, 2014, Mar-27, Volume: 2014

    Topics: Adult; Aromatase Inhibitors; Estrogen Replacement Therapy; Estrogens; Female; Humans; Hysterectomy;

2014
Three-month treatment with triptorelin, letrozole and ulipristal acetate before hysteroscopic resection of uterine myomas: prospective comparative pilot study.
    European journal of obstetrics, gynecology, and reproductive biology, 2015, Volume: 192

    Topics: Adult; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Attitude of Health Personnel; Contrace

2015
Three-month treatment with triptorelin, letrozole and ulipristal acetate before hysteroscopic resection of uterine myomas: prospective comparative pilot study.
    European journal of obstetrics, gynecology, and reproductive biology, 2015, Volume: 192

    Topics: Adult; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Attitude of Health Personnel; Contrace

2015
Letrozole monotherapy in the treatment of uterine myomas.
    Fertility and sterility, 2010, May-01, Volume: 93, Issue:7

    Topics: Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Fema

2010
Letrozole monotherapy in the treatment of uterine myomas.
    Fertility and sterility, 2010, May-01, Volume: 93, Issue:7

    Topics: Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Fema

2010
Lobular carcinoma of the breast metastasizing to leiomyoma in a patient under letrozole treatment.
    European journal of gynaecological oncology, 2011, Volume: 32, Issue:5

    Topics: Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Lobular; Female; Humans; Leiomyoma; Letrozole; Mi

2011
Lobular carcinoma of the breast metastasizing to leiomyoma in a patient under letrozole treatment.
    European journal of gynaecological oncology, 2011, Volume: 32, Issue:5

    Topics: Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Lobular; Female; Humans; Leiomyoma; Letrozole; Mi

2011
Uterine metastasis of lobular breast cancer during adjuvant letrozole therapy.
    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2013, Volume: 33, Issue:1

    Topics: Antigens, Tumor-Associated, Carbohydrate; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Lobula

2013
Uterine metastasis of lobular breast cancer during adjuvant letrozole therapy.
    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2013, Volume: 33, Issue:1

    Topics: Antigens, Tumor-Associated, Carbohydrate; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Lobula

2013
Harm or benefit of hormonal treatment in metastatic low-grade endometrial stromal sarcoma: single center experience with 10 cases and review of the literature.
    Gynecologic oncology, 2006, Volume: 101, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Endometrial Stromal Tumors; Estrogen Replacement Thera

2006
Harm or benefit of hormonal treatment in metastatic low-grade endometrial stromal sarcoma: single center experience with 10 cases and review of the literature.
    Gynecologic oncology, 2006, Volume: 101, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Endometrial Stromal Tumors; Estrogen Replacement Thera

2006
[Pulmonary metastases from endometrial stromal sarcoma may benefit from hormone therapy].
    Revue des maladies respiratoires, 2007, Volume: 24, Issue:1

    Topics: Aromatase Inhibitors; Endometrial Neoplasms; Female; Humans; Letrozole; Lung Neoplasms; Middle Aged;

2007
[Pulmonary metastases from endometrial stromal sarcoma may benefit from hormone therapy].
    Revue des maladies respiratoires, 2007, Volume: 24, Issue:1

    Topics: Aromatase Inhibitors; Endometrial Neoplasms; Female; Humans; Letrozole; Lung Neoplasms; Middle Aged;

2007
Intravenous leiomyomatosis treated with aromatase inhibitor therapy.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2008, Volume: 101, Issue:3

    Topics: Adult; Angiography; Aromatase Inhibitors; Female; Humans; Leiomyomatosis; Letrozole; Nitriles; Treat

2008
Intravenous leiomyomatosis treated with aromatase inhibitor therapy.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2008, Volume: 101, Issue:3

    Topics: Adult; Angiography; Aromatase Inhibitors; Female; Humans; Leiomyomatosis; Letrozole; Nitriles; Treat

2008
Anticancer therapy in patients with porphyrias: evidence today.
    Expert opinion on drug safety, 2008, Volume: 7, Issue:2

    Topics: Anastrozole; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Docetaxel; Epoetin Alfa;

2008
Anticancer therapy in patients with porphyrias: evidence today.
    Expert opinion on drug safety, 2008, Volume: 7, Issue:2

    Topics: Anastrozole; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Docetaxel; Epoetin Alfa;

2008
[Neoadjuvant use of the aromatase inhibitor letrozole in uterine cancer: endocrine and clinical effects].
    Voprosy onkologii, 2001, Volume: 47, Issue:5

    Topics: Antineoplastic Agents; Aromatase Inhibitors; Blood Glucose; Chemotherapy, Adjuvant; Enzyme Inhibitor

2001
[Neoadjuvant use of the aromatase inhibitor letrozole in uterine cancer: endocrine and clinical effects].
    Voprosy onkologii, 2001, Volume: 47, Issue:5

    Topics: Antineoplastic Agents; Aromatase Inhibitors; Blood Glucose; Chemotherapy, Adjuvant; Enzyme Inhibitor

2001
17alpha-methyl testosterone is a competitive inhibitor of aromatase activity in Jar choriocarcinoma cells and macrophage-like THP-1 cells in culture.
    The Journal of steroid biochemistry and molecular biology, 2001, Volume: 79, Issue:1-5

    Topics: Aromatase; Aromatase Inhibitors; Binding, Competitive; Cell Line; Choriocarcinoma; Dose-Response Rel

2001
17alpha-methyl testosterone is a competitive inhibitor of aromatase activity in Jar choriocarcinoma cells and macrophage-like THP-1 cells in culture.
    The Journal of steroid biochemistry and molecular biology, 2001, Volume: 79, Issue:1-5

    Topics: Aromatase; Aromatase Inhibitors; Binding, Competitive; Cell Line; Choriocarcinoma; Dose-Response Rel

2001
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