Page last updated: 2024-10-30

letrozole and Sterility, Male

letrozole has been researched along with Sterility, Male in 19 studies

Research Excerpts

ExcerptRelevanceReference
"To study the feasibility of a randomized controlled trial (RCT) comparing intrauterine insemination (IUI) with and without letrozole in couples with unexplained or mild male factor infertility STUDY DESIGN: We performed a randomized pilot study including 100 couples with unexplained or mild male factor infertility in the Reproductive Medicine Centre of Peking University Third Hospital in China."9.41Intrauterine insemination (IUI) with or without letrozole for unexplained or mild male factor infertility: A randomized pilot study. ( Huang, S; Li, N; Li, R; Luo, L; Mol, BWJ; Norman, RJ; Qiao, J; Wang, H; Wang, L; Wang, R; Yan, H, 2021)
"To study the feasibility of a randomized controlled trial (RCT) comparing intrauterine insemination (IUI) with and without letrozole in couples with unexplained or mild male factor infertility STUDY DESIGN: We performed a randomized pilot study including 100 couples with unexplained or mild male factor infertility in the Reproductive Medicine Centre of Peking University Third Hospital in China."5.41Intrauterine insemination (IUI) with or without letrozole for unexplained or mild male factor infertility: A randomized pilot study. ( Huang, S; Li, N; Li, R; Luo, L; Mol, BWJ; Norman, RJ; Qiao, J; Wang, H; Wang, L; Wang, R; Yan, H, 2021)
" A total of 750 infertile women with polycystic ovary syndrome (PCOS) were randomly assigned to up to receive five cycles of letrozole or clomiphene citrate."5.20Impact of Male and Female Weight, Smoking, and Intercourse Frequency on Live Birth in Women With Polycystic Ovary Syndrome. ( Allshouse, AA; Alvero, R; Casson, PR; Christman, GM; Coutifaris, C; Diamond, MP; Eisenberg, E; Krawetz, SA; Legro, RS; Polotsky, AJ; Santoro, N; Schlaff, WD; Trussell, JC; Zhang, H, 2015)
"In normo-ovulatory women undergoing TDI, OS with CC or letrozole resulted in similar live birth and twin pregnancy rates."3.85Clomiphene Citrate versus Letrozole for Ovarian Stimulation in Therapeutic Donor Sperm Insemination. ( Antaki, R; Bouet, PE; El Hachem, H; Kadoch, IJ; Lapensée, L; Sylvestre, C, 2017)
"Pregnancy rates were comparable between the letrozole-FSH co-treatment group and the FSH alone group."3.75Letrozole co-treatment in infertile women 40 years old and older receiving controlled ovarian stimulation and intrauterine insemination. ( Bedaiwy, MA; Casper, R; Claessens, A; Esfandiari, N; Gotleib, L; Mousa, N; Shokry, M, 2009)
"Letrozole treatment can effectively increase spontaneous pregnancies by improving sperm parameters and sperm chromatin integrity in men with iOAT and T:E2 ratio ≤ 10."2.94Effect of Letrozole on sperm parameters, chromatin status and ROS level in idiopathic Oligo/Astheno/Teratozoospermia. ( Bahmanpour, S; Kooshesh, L; Nasr-Esfahani, MH; Zeighami, S, 2020)
"AIs may be effective in the treatment of male infertility."2.82Efficacy and safety of letrozole or anastrozole in the treatment of male infertility with low testosterone-estradiol ratio: A meta-analysis and systematic review. ( Guo, B; Li, JJ; Liu, JG; Ma, YL; Zhao, YT, 2022)
"For decades, AIs have been used to treat male infertility empirically."2.72Clinical application of aromatase inhibitors to treat male infertility. ( Li, P; Li, Z; Yang, C, 2021)
"Letrozole is a highly effective nonsteroidal aromatase inhibitor that has been used to treat male subfertility in several case series with promising results."2.49Big enough for an aromatase inhibitor? How adiposity affects male fertility. ( Polotsky, AJ; Stephens, SM, 2013)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (15.79)29.6817
2010's12 (63.16)24.3611
2020's4 (21.05)2.80

Authors

AuthorsStudies
Yang, C1
Li, P1
Li, Z1
Guo, B1
Li, JJ1
Ma, YL1
Zhao, YT1
Liu, JG1
Peivandi, S1
Jafarpour, H1
Abbaspour, M1
Ebadi, A1
Kooshesh, L1
Bahmanpour, S1
Zeighami, S1
Nasr-Esfahani, MH1
Huang, S1
Wang, R1
Yan, H1
Li, N1
Wang, H1
Luo, L1
Wang, L1
Norman, RJ1
Li, R1
Qiao, J1
Mol, BWJ1
Ali, EA1
Zhandi, M1
Towhidi, A1
Zaghari, M1
Ansari, M1
Najafi, M1
Deldar, H1
Adeldust, H1
Farzinpour, A1
Farshad, A1
Rostamzadeh, J1
Lopez-Bejar, M1
Shuling, L1
Sie Kuei, ML1
Saffari, SE1
Jiayun, Z1
Yeun, TT1
Leng, JPW1
Viardot-Foucault, V1
Nadarajah, S1
Chan, JKY1
Hao, TH1
Stephens, SM1
Polotsky, AJ2
Zhao, D1
Pan, L1
Zhang, F1
Pan, F1
Ma, J1
Zhang, X1
Liu, Y1
Ganesh, A1
Chauhan, N1
Das, S1
Chakravarty, B1
Chaudhury, K1
Luco, SM1
Agbo, C1
Behr, B1
Dahan, MH1
Allshouse, AA1
Casson, PR1
Coutifaris, C1
Diamond, MP1
Christman, GM1
Schlaff, WD1
Alvero, R1
Trussell, JC1
Krawetz, SA1
Santoro, N1
Eisenberg, E1
Zhang, H1
Legro, RS1
El Hachem, H1
Antaki, R1
Sylvestre, C1
Kadoch, IJ1
Lapensée, L1
Bouet, PE1
Saylam, B1
Efesoy, O1
Cayan, S1
Gregoriou, O1
Bakas, P1
Grigoriadis, C1
Creatsa, M1
Hassiakos, D1
Creatsas, G1
Bedaiwy, MA2
Forman, R1
Mousa, NA1
Al Inany, HG1
Casper, RF1
Verpoest, WM1
Kolibianakis, E1
Papanikolaou, E1
Smitz, J1
Van Steirteghem, A1
Devroey, P1
Shokry, M1
Mousa, N1
Claessens, A1
Esfandiari, N1
Gotleib, L1
Casper, R1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Scientific & Clinical Review of Minimal Stimulation Protocol Using AROMEK (Letrozole) and Follitrope (Recombinant FSH)Combined With INVOCell(Intravaginal Culturing) - Effectiveness as Low Cost IVF[NCT01058252]30 participants (Anticipated)Observational2021-05-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for letrozole and Sterility, Male

ArticleYear
Clinical application of aromatase inhibitors to treat male infertility.
    Human reproduction update, 2021, 12-21, Volume: 28, Issue:1

    Topics: Anastrozole; Aromatase; Aromatase Inhibitors; Humans; Infertility, Male; Letrozole; Male; Semen Anal

2021
Efficacy and safety of letrozole or anastrozole in the treatment of male infertility with low testosterone-estradiol ratio: A meta-analysis and systematic review.
    Andrology, 2022, Volume: 10, Issue:5

    Topics: Anastrozole; Estradiol; Female; Follicle Stimulating Hormone; Humans; Infertility, Male; Letrozole;

2022
Big enough for an aromatase inhibitor? How adiposity affects male fertility.
    Seminars in reproductive medicine, 2013, Volume: 31, Issue:4

    Topics: Adiposity; Aromatase Inhibitors; Evidence-Based Medicine; Humans; Infertility, Male; Letrozole; Male

2013
The evaluation of pre and post processing semen analysis parameters at the time of intrauterine insemination in couples diagnosed with male factor infertility and pregnancy rates based on stimulation agent. A retrospective cohort study.
    European journal of obstetrics, gynecology, and reproductive biology, 2014, Volume: 179

    Topics: Adult; Aromatase Inhibitors; Female; Humans; Infertility, Male; Insemination, Artificial, Homologous

2014

Trials

8 trials available for letrozole and Sterility, Male

ArticleYear
Effect of letrozole on spermogram parameters and hormonal profile in infertile men: A clinical trial study.
    Endocrine regulations, 2019, Oct-01, Volume: 53, Issue:4

    Topics: Adult; Aromatase Inhibitors; Estradiol; Humans; Infertility, Male; Iran; Letrozole; Male; Middle Age

2019
Effect of Letrozole on sperm parameters, chromatin status and ROS level in idiopathic Oligo/Astheno/Teratozoospermia.
    Reproductive biology and endocrinology : RB&E, 2020, May-13, Volume: 18, Issue:1

    Topics: Adult; Asthenozoospermia; Chromatin; DNA Fragmentation; Humans; Infertility, Male; Letrozole; Longit

2020
Intrauterine insemination (IUI) with or without letrozole for unexplained or mild male factor infertility: A randomized pilot study.
    European journal of obstetrics, gynecology, and reproductive biology, 2021, Volume: 262

    Topics: China; Female; Humans; Infertility; Infertility, Male; Insemination; Insemination, Artificial; Letro

2021
Impact of Male and Female Weight, Smoking, and Intercourse Frequency on Live Birth in Women With Polycystic Ovary Syndrome.
    The Journal of clinical endocrinology and metabolism, 2015, Volume: 100, Issue:6

    Topics: Adolescent; Adult; Body Mass Index; Body Weight; Clomiphene; Coitus; Female; Fertility Agents, Femal

2015
The effect of aromatase inhibitor letrozole on body mass index, serum hormones, and sperm parameters in infertile men.
    Fertility and sterility, 2011, Volume: 95, Issue:2

    Topics: Adult; Aromatase Inhibitors; Body Mass Index; Estradiol; Hormones; Humans; Infertility, Male; Letroz

2011
Changes in hormonal profile and seminal parameters with use of aromatase inhibitors in management of infertile men with low testosterone to estradiol ratios.
    Fertility and sterility, 2012, Volume: 98, Issue:1

    Topics: Adult; Anastrozole; Aromatase Inhibitors; Estradiol; Hormones; Humans; Infertility, Male; Letrozole;

2012
Cost-effectiveness of aromatase inhibitor co-treatment for controlled ovarian stimulation.
    Human reproduction (Oxford, England), 2006, Volume: 21, Issue:11

    Topics: Aromatase Inhibitors; Cost-Benefit Analysis; Costs and Cost Analysis; Endometrium; Female; Follicle

2006
Aromatase inhibitors in ovarian stimulation for IVF/ICSI: a pilot study.
    Reproductive biomedicine online, 2006, Volume: 13, Issue:2

    Topics: Adult; Aromatase Inhibitors; Drug Therapy, Combination; Female; Fertilization in Vitro; Follicle Sti

2006

Other Studies

7 other studies available for letrozole and Sterility, Male

ArticleYear
Letrozole, an aromatase inhibitor, reduces post-peak age-related regression of rooster reproductive performance.
    Animal reproduction science, 2017, Volume: 183

    Topics: Aging; Animals; Chickens; Infertility, Male; Insemination, Artificial; Letrozole; Lipid Peroxidation

2017
Increased sperm cell production in ageing roosters by an oral treatment with an aromatase inhibitor and a natural herbal extract designed for improving fertility.
    Reproduction in domestic animals = Zuchthygiene, 2017, Volume: 52 Suppl 4

    Topics: Administration, Oral; Aging; Animals; Aromatase Inhibitors; Chickens; Epididymis; Infertility, Male;

2017
Do men with normal testosterone-oestradiol ratios benefit from letrozole for the treatment of male infertility?
    Reproductive biomedicine online, 2019, Volume: 38, Issue:1

    Topics: Adult; Aromatase Inhibitors; Estradiol; Humans; Infertility, Male; Letrozole; Male; Middle Aged; Oli

2019
Successful use of aromatase inhibitor letrozole in NOA with an elevated FSH level: a case report.
    Andrologia, 2014, Volume: 46, Issue:4

    Topics: Adult; Aromatase Inhibitors; Follicle Stimulating Hormone; Humans; Infertility, Male; Letrozole; Mal

2014
Endometrial receptivity markers in infertile women stimulated with letrozole compared with clomiphene citrate and natural cycles.
    Systems biology in reproductive medicine, 2014, Volume: 60, Issue:2

    Topics: Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Female; Humans; Infertility, Female; Inf

2014
Clomiphene Citrate versus Letrozole for Ovarian Stimulation in Therapeutic Donor Sperm Insemination.
    Gynecologic and obstetric investigation, 2017, Volume: 82, Issue:5

    Topics: Adult; Aromatase Inhibitors; Canada; Clomiphene; Female; Fertility Agents, Female; Humans; Infertili

2017
Letrozole co-treatment in infertile women 40 years old and older receiving controlled ovarian stimulation and intrauterine insemination.
    Fertility and sterility, 2009, Volume: 91, Issue:6

    Topics: Adult; Aromatase Inhibitors; Case-Control Studies; Drug Therapy, Combination; Endometriosis; Female;

2009