letrozole has been researched along with Puberty, Precocious in 11 studies
Puberty, Precocious: Development of SEXUAL MATURATION in boys and girls at a chronological age that is 2.5 standard deviations below the mean age at onset of PUBERTY in the population. This early maturation of the hypothalamic-pituitary-gonadal axis results in sexual precocity, elevated serum levels of GONADOTROPINS and GONADAL STEROID HORMONES such as ESTRADIOL and TESTOSTERONE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the efficacy and safety of the third-generation aromatase inhibitor letrozole in the treatment of McCune-Albright syndrome (MAS) girls with peripheral precocious puberty." | 7.96 | [Efficacy and safety of letrozole in treatment of McCune-Albright syndrome girls with peripheral precocious puberty]. ( Dong, Z; Lu, W; Wang, J; Wang, W; Wang, X; Xie, Y, 2020) |
| "To assess the efficacy of letrozole in treatment of children with congenital adrenal hyperplasia (CAH) due to steroid 21-hydroxylase deficiency (21-OHD)." | 7.96 | [Efficacy of letrozole in treatment of children with congenital adrenal hyperplasia due to steroid 21-hydroxylase deficiency]. ( Li, G; Ma, X; Wang, F; Wang, Q; Wang, Z; Zhang, S, 2020) |
| "Girls with McCune-Albright syndrome (MAS) and related disorders have gonadotropin-independent precocious puberty due to estrogen secretion from ovarian cysts." | 6.73 | Letrozole treatment of precocious puberty in girls with the McCune-Albright syndrome: a pilot study. ( Calis, K; Collins, MT; Feuillan, P; Hill, S; Robey, PG; Shawker, T, 2007) |
| "Letrozole treatment was highly effective at decreasing the rate of skeletal maturation, with a decline in change in bone age over change in chronological age (ΔBA/ΔCA) from 1." | 5.43 | Long-term outcomes of letrozole treatment for precocious puberty in girls with McCune-Albright syndrome. ( Boyce, AM; Brillante, BA; Collins, MT; Estrada, A; Gafni, RI; Guthrie, LC, 2016) |
| "To evaluate the efficacy and safety of the third-generation aromatase inhibitor letrozole in the treatment of McCune-Albright syndrome (MAS) girls with peripheral precocious puberty." | 3.96 | [Efficacy and safety of letrozole in treatment of McCune-Albright syndrome girls with peripheral precocious puberty]. ( Dong, Z; Lu, W; Wang, J; Wang, W; Wang, X; Xie, Y, 2020) |
| "To assess the efficacy of letrozole in treatment of children with congenital adrenal hyperplasia (CAH) due to steroid 21-hydroxylase deficiency (21-OHD)." | 3.96 | [Efficacy of letrozole in treatment of children with congenital adrenal hyperplasia due to steroid 21-hydroxylase deficiency]. ( Li, G; Ma, X; Wang, F; Wang, Q; Wang, Z; Zhang, S, 2020) |
| "The letrozole treatment group received oral letrozole [2." | 2.79 | [Clinical efficacy of letrozole in boys with idiopathic central precocious puberty]. ( Zhang, Q; Zhao, X, 2014) |
| "Girls with McCune-Albright syndrome (MAS) and related disorders have gonadotropin-independent precocious puberty due to estrogen secretion from ovarian cysts." | 2.73 | Letrozole treatment of precocious puberty in girls with the McCune-Albright syndrome: a pilot study. ( Calis, K; Collins, MT; Feuillan, P; Hill, S; Robey, PG; Shawker, T, 2007) |
| "McCune-Albright syndrome (MAS) is a rare disease defined by the triad of fibrous dysplasia (FD), café au lait spots, and peripheral precocious puberty (PP)." | 1.43 | Clinical and endocrine characteristics and genetic analysis of Korean children with McCune-Albright syndrome: a retrospective cohort study. ( Cho, EK; Cho, SY; Jin, DK; Ki, CS; Kim, J; Lee, JE; Yang, A, 2016) |
| "Letrozole treatment was highly effective at decreasing the rate of skeletal maturation, with a decline in change in bone age over change in chronological age (ΔBA/ΔCA) from 1." | 1.43 | Long-term outcomes of letrozole treatment for precocious puberty in girls with McCune-Albright syndrome. ( Boyce, AM; Brillante, BA; Collins, MT; Estrada, A; Gafni, RI; Guthrie, LC, 2016) |
| "McCune-Albright syndrome is a rare syndrome, classically defined as the triad of precocious puberty, fibrous dysplasia of bone, and café au lait lesions." | 1.38 | Diagnosis and management of precocious puberty in atypical presentations of McCune-Albright syndrome: a case series review. ( Bercaw-Pratt, JL; Dietrich, JE; Karaviti, L; Moorjani, TP; Santos, XM, 2012) |
| "McCune-Albright syndrome (MAS) is a triad of gonadotropin-independent precocious puberty (GIPP), café-au-lait spots (CALS) and fibrous dysplasia (FD) of bone." | 1.36 | McCune-Albright syndrome (MAS): early and extensive bone fibrous dysplasia involvement and "mistaken identity" oophorectomy. ( Gucev, Z; Jancevska, A; Krstevska-Konstantinova, M; Pop-Jordanova, N; Tasic, V, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 7 (63.64) | 24.3611 |
| 2020's | 3 (27.27) | 2.80 |
| Authors | Studies |
|---|---|
| Yuan, X | 1 |
| Chen, R | 1 |
| Zhang, Y | 1 |
| Yang, X | 1 |
| Lin, X | 1 |
| Lu, W | 1 |
| Wang, X | 1 |
| Wang, J | 1 |
| Xie, Y | 1 |
| Dong, Z | 1 |
| Wang, W | 1 |
| Wang, Q | 1 |
| Zhang, S | 1 |
| Ma, X | 1 |
| Li, G | 1 |
| Wang, Z | 1 |
| Wang, F | 1 |
| Neyman, A | 1 |
| Eugster, EA | 2 |
| Zhao, X | 1 |
| Zhang, Q | 1 |
| Cho, EK | 1 |
| Kim, J | 1 |
| Yang, A | 1 |
| Ki, CS | 1 |
| Lee, JE | 1 |
| Cho, SY | 1 |
| Jin, DK | 1 |
| Estrada, A | 1 |
| Boyce, AM | 1 |
| Brillante, BA | 1 |
| Guthrie, LC | 1 |
| Gafni, RI | 1 |
| Collins, MT | 2 |
| Lenz, AM | 1 |
| Shulman, D | 1 |
| Rahhal, S | 1 |
| Fuqua, JS | 1 |
| Pescovitz, OH | 1 |
| Lewis, KA | 1 |
| Gucev, Z | 1 |
| Tasic, V | 1 |
| Jancevska, A | 1 |
| Krstevska-Konstantinova, M | 1 |
| Pop-Jordanova, N | 1 |
| Bercaw-Pratt, JL | 1 |
| Moorjani, TP | 1 |
| Santos, XM | 1 |
| Karaviti, L | 1 |
| Dietrich, JE | 1 |
| Feuillan, P | 1 |
| Calis, K | 1 |
| Hill, S | 1 |
| Shawker, T | 1 |
| Robey, PG | 1 |
2 trials available for letrozole and Puberty, Precocious
| Article | Year |
|---|---|
[Clinical efficacy of letrozole in boys with idiopathic central precocious puberty].
Topics: Adolescent; Aromatase Inhibitors; Body Height; Bone Development; Gonadal Steroid Hormones; Humans; L | 2014 |
Letrozole treatment of precocious puberty in girls with the McCune-Albright syndrome: a pilot study.
Topics: Antineoplastic Agents; Biomarkers; Bone and Bones; Child; Child, Preschool; Female; Fibrous Dysplasi | 2007 |
9 other studies available for letrozole and Puberty, Precocious
| Article | Year |
|---|---|
Long-Term Treatment With Letrozole in a Boy With Familial Male-Limited Precocious Puberty.
Topics: Adult; Child; Child, Preschool; Humans; Letrozole; Male; Puberty, Precocious; Spironolactone; Tripto | 2022 |
[Efficacy and safety of letrozole in treatment of McCune-Albright syndrome girls with peripheral precocious puberty].
Topics: Aromatase Inhibitors; Child; China; Female; Fibrous Dysplasia, Polyostotic; Humans; Letrozole; Puber | 2020 |
[Efficacy of letrozole in treatment of children with congenital adrenal hyperplasia due to steroid 21-hydroxylase deficiency].
Topics: Adrenal Hyperplasia, Congenital; Body Height; Child; Child, Preschool; Female; Humans; Letrozole; Ma | 2020 |
Treatment of Girls and Boys with McCune-Albright Syndrome with Precocious Puberty - Update 2017.
Topics: Aromatase Inhibitors; Female; Fibrous Dysplasia, Polyostotic; Humans; Letrozole; Male; Puberty, Prec | 2017 |
Clinical and endocrine characteristics and genetic analysis of Korean children with McCune-Albright syndrome: a retrospective cohort study.
Topics: Acromegaly; Adolescent; Cafe-au-Lait Spots; Child; Child, Preschool; Chromogranins; Female; Fibrous | 2016 |
Long-term outcomes of letrozole treatment for precocious puberty in girls with McCune-Albright syndrome.
Topics: Aromatase Inhibitors; Body Height; Child; Child, Preschool; Cohort Studies; Drug Administration Sche | 2016 |
Bicalutamide and third-generation aromatase inhibitors in testotoxicosis.
Topics: Anastrozole; Androgen Antagonists; Anilides; Aromatase Inhibitors; Child, Preschool; Humans; Letrozo | 2010 |
McCune-Albright syndrome (MAS): early and extensive bone fibrous dysplasia involvement and "mistaken identity" oophorectomy.
Topics: Aromatase Inhibitors; Child, Preschool; Female; Fibrous Dysplasia, Polyostotic; Follicle Stimulating | 2010 |
Diagnosis and management of precocious puberty in atypical presentations of McCune-Albright syndrome: a case series review.
Topics: Aromatase Inhibitors; Child, Preschool; Diagnosis, Differential; Female; Fibrous Dysplasia, Polyosto | 2012 |