letrozole has been researched along with Klinefelter Syndrome in 1 studies
Klinefelter Syndrome: A form of male HYPOGONADISM, characterized by the presence of an extra X CHROMOSOME, small TESTES, seminiferous tubule dysgenesis, elevated levels of GONADOTROPINS, low serum TESTOSTERONE, underdeveloped secondary sex characteristics, and male infertility (INFERTILITY, MALE). Patients tend to have long legs and a slim, tall stature. GYNECOMASTIA is present in many of the patients. The classic form has the karyotype 47,XXY. Several karyotype variants include 48,XXYY; 48,XXXY; 49,XXXXY, and mosaic patterns ( 46,XY/47,XXY; 47,XXY/48,XXXY, etc.).
| Excerpt | Relevance | Reference |
|---|---|---|
| " ISS boys with letrozole-induced hypergonadotropic hyperandrogenism had, after 12 months of therapy, higher INSL3 levels than did placebo treated (0." | 5.12 | Serum insulin-like factor 3 levels during puberty in healthy boys and boys with Klinefelter syndrome. ( Andersson, AM; Bay, K; Dunkel, L; Hero, M; Wikström, AM, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wikström, AM | 1 |
| Bay, K | 1 |
| Hero, M | 1 |
| Andersson, AM | 1 |
| Dunkel, L | 1 |
1 trial available for letrozole and Klinefelter Syndrome
| Article | Year |
|---|---|
Serum insulin-like factor 3 levels during puberty in healthy boys and boys with Klinefelter syndrome.
Topics: Adolescent; Age Determination by Skeleton; Aromatase Inhibitors; Body Height; Child; Dwarfism; Healt | 2006 |