letrozole has been researched along with Inflammation in 14 studies
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of this study was to investigate the effect of LDS on dyslipidemia and hepatic inflammation in rats with letrozole (LET)-induced PCOS and to assess the possible involvement of PCSK9 in these effects." | 8.31 | Low-dose spironolactone combats dyslipidemia and hepatic inflammation by modulating PCSK9 in rat model of polycystic ovarian syndrome. ( Agbana, RD; Ajadi, IO; Areloegbe, SE; Areola, ED; Atuma, CL; Fafure, AA; Olaniyi, KS; Olatunji, LA; Sabinari, IW; Shah, MZUH, 2023) |
| " Consequently, we aimed to investigate the effects of metformin, letrozole, and atorvastatin on inflammation and apoptosis in experimentally induced ovarian and peritoneal endometriosis in rat models." | 8.12 | Effects of metformin, letrozole and atorvastatin on inflammation and apoptosis in experimental peritoneal and ovarian endometriosis in the rat. ( Coskun, G; Efendic, F; Erdem, E; Hayretdag, C; Irkorucu, O; Keles, P; Kuras, S; Pence, HH; Polat, S; Saker, D; Sapmaz, E; Sapmaz, T; Sevgin, K; Tekayev, M; Topkaraoglu, S, 2022) |
| "Altogether, the present study suggests that low-dose spironolactone confers protection against adipose dysfunction in experimental PCOS animals by attenuating inflammation, oxidative stress and cellular apoptosis." | 8.12 | Low-dose spironolactone ameliorates adipose tissue inflammation and apoptosis in letrozole-induced PCOS rat model. ( Areloegbe, SE; Olaniyi, KS; Oyeleke, MB; Peter, MU, 2022) |
| "The aims of the current study were to examine the effects of temporal changes in oxidative stress (OS) and low-grade inflammation in letrozole-treated rats and to correlate these changes with the development of polycystic ovary syndrome (PCOS)-like features." | 7.83 | Role of oxidative stress and low-grade inflammation in letrozole-induced polycystic ovary syndrome in the rat. ( Krishna, A; Pandey, U; Pandey, V; Singh, A; Tripathi, YB, 2016) |
| " First, letrozole was used to induce the PCOS model, 24 h food intake, 24 h body weight changes and the expression of p-STAT3 were determined following leptin or artificial cerebrospinal fluid (aCSF) icv injection in rats." | 7.83 | Central leptin resistance and hypothalamic inflammation are involved in letrozole-induced polycystic ovary syndrome rats. ( Lian, Y; Wang, W; Zhao, F, 2016) |
| " The aim of this study was to investigate the effect of LDS on dyslipidemia and hepatic inflammation in rats with letrozole (LET)-induced PCOS and to assess the possible involvement of PCSK9 in these effects." | 4.31 | Low-dose spironolactone combats dyslipidemia and hepatic inflammation by modulating PCSK9 in rat model of polycystic ovarian syndrome. ( Agbana, RD; Ajadi, IO; Areloegbe, SE; Areola, ED; Atuma, CL; Fafure, AA; Olaniyi, KS; Olatunji, LA; Sabinari, IW; Shah, MZUH, 2023) |
| " Consequently, we aimed to investigate the effects of metformin, letrozole, and atorvastatin on inflammation and apoptosis in experimentally induced ovarian and peritoneal endometriosis in rat models." | 4.12 | Effects of metformin, letrozole and atorvastatin on inflammation and apoptosis in experimental peritoneal and ovarian endometriosis in the rat. ( Coskun, G; Efendic, F; Erdem, E; Hayretdag, C; Irkorucu, O; Keles, P; Kuras, S; Pence, HH; Polat, S; Saker, D; Sapmaz, E; Sapmaz, T; Sevgin, K; Tekayev, M; Topkaraoglu, S, 2022) |
| "Altogether, the present study suggests that low-dose spironolactone confers protection against adipose dysfunction in experimental PCOS animals by attenuating inflammation, oxidative stress and cellular apoptosis." | 4.12 | Low-dose spironolactone ameliorates adipose tissue inflammation and apoptosis in letrozole-induced PCOS rat model. ( Areloegbe, SE; Olaniyi, KS; Oyeleke, MB; Peter, MU, 2022) |
| "The objective of our study was to investigate glycemic, oxidative/antioxidative and inflammatory status in letrozole and estradiol valerate induced polycystic ovarian syndrome (PCOS) models." | 3.83 | Letrozole vs estradiol valerate induced PCOS in rats: glycemic, oxidative and inflammatory status assessment. ( Cucolaş, C; Dăneasă, A; Filip, GA; Lenghel, LM; Olteanu, D; Orăsan, R, 2016) |
| "The aims of the current study were to examine the effects of temporal changes in oxidative stress (OS) and low-grade inflammation in letrozole-treated rats and to correlate these changes with the development of polycystic ovary syndrome (PCOS)-like features." | 3.83 | Role of oxidative stress and low-grade inflammation in letrozole-induced polycystic ovary syndrome in the rat. ( Krishna, A; Pandey, U; Pandey, V; Singh, A; Tripathi, YB, 2016) |
| " First, letrozole was used to induce the PCOS model, 24 h food intake, 24 h body weight changes and the expression of p-STAT3 were determined following leptin or artificial cerebrospinal fluid (aCSF) icv injection in rats." | 3.83 | Central leptin resistance and hypothalamic inflammation are involved in letrozole-induced polycystic ovary syndrome rats. ( Lian, Y; Wang, W; Zhao, F, 2016) |
| "Use of aromatase inhibitors (AIs), exemestane, letrozole and anastrozole, for breast cancer therapy is associated with severe pain symptoms, the underlying mechanism of which is unknown." | 3.80 | Steroidal and non-steroidal third-generation aromatase inhibitors induce pain-like symptoms via TRPA1. ( Benemei, S; Coppi, E; De Logu, F; Di Tommaso, MR; Fusi, C; Geppetti, P; Marone, IM; Materazzi, S; Minocci, D; Moneti, G; Nassini, R; Pieraccini, G; Susini, T; Trevisan, G; Tuccinardi, T, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (57.14) | 24.3611 |
| 2020's | 6 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 1 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| Olaniyi, KS | 4 |
| Areloegbe, SE | 3 |
| Sapmaz, T | 1 |
| Coskun, G | 1 |
| Saker, D | 1 |
| Pence, HH | 1 |
| Keles, P | 1 |
| Hayretdag, C | 1 |
| Kuras, S | 1 |
| Topkaraoglu, S | 1 |
| Erdem, E | 1 |
| Efendic, F | 1 |
| Sevgin, K | 1 |
| Tekayev, M | 1 |
| Polat, S | 1 |
| Sapmaz, E | 1 |
| Irkorucu, O | 1 |
| Peter, MU | 1 |
| Oyeleke, MB | 1 |
| Areola, ED | 1 |
| Sabinari, IW | 1 |
| Fafure, AA | 1 |
| Agbana, RD | 1 |
| Atuma, CL | 1 |
| Shah, MZUH | 1 |
| Ajadi, IO | 1 |
| Olatunji, LA | 1 |
| Zuo, W | 2 |
| Liu, X | 1 |
| Chen, J | 1 |
| Yin, Y | 1 |
| Nie, X | 1 |
| Tang, P | 1 |
| Huang, Y | 1 |
| Yu, Q | 1 |
| Hu, Q | 1 |
| Zhou, J | 1 |
| Tan, Y | 1 |
| Huang, X | 1 |
| Ren, Q | 1 |
| Bashir, AM | 1 |
| Makary, S | 1 |
| Abdo, M | 1 |
| Fekry, E | 1 |
| Choi, HS | 1 |
| Lee, MJ | 1 |
| Choi, SR | 1 |
| Smeester, BA | 1 |
| Beitz, AJ | 1 |
| Lee, JH | 1 |
| Fusi, C | 1 |
| Materazzi, S | 1 |
| Benemei, S | 1 |
| Coppi, E | 1 |
| Trevisan, G | 1 |
| Marone, IM | 1 |
| Minocci, D | 1 |
| De Logu, F | 1 |
| Tuccinardi, T | 1 |
| Di Tommaso, MR | 1 |
| Susini, T | 1 |
| Moneti, G | 1 |
| Pieraccini, G | 1 |
| Geppetti, P | 1 |
| Nassini, R | 1 |
| Zhao, Y | 1 |
| Gong, P | 1 |
| Chen, Y | 1 |
| Nwachukwu, JC | 1 |
| Srinivasan, S | 1 |
| Ko, C | 1 |
| Bagchi, MK | 1 |
| Taylor, RN | 1 |
| Korach, KS | 1 |
| Nettles, KW | 1 |
| Katzenellenbogen, JA | 1 |
| Katzenellenbogen, BS | 1 |
| Dăneasă, A | 1 |
| Cucolaş, C | 1 |
| Lenghel, LM | 1 |
| Olteanu, D | 1 |
| Orăsan, R | 1 |
| Filip, GA | 1 |
| Pandey, V | 1 |
| Singh, A | 2 |
| Krishna, A | 1 |
| Pandey, U | 1 |
| Tripathi, YB | 1 |
| Lian, Y | 1 |
| Zhao, F | 1 |
| Wang, W | 1 |
14 other studies available for letrozole and Inflammation
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
Suppression of PCSK9/NF-kB-dependent pathways by acetate ameliorates cardiac inflammation in a rat model of polycystic ovarian syndrome.
Topics: Acetates; Animals; Cardiovascular Diseases; Disease Models, Animal; Female; Humans; Inflammation; Le | 2022 |
Effects of metformin, letrozole and atorvastatin on inflammation and apoptosis in experimental peritoneal and ovarian endometriosis in the rat.
Topics: Animals; Apoptosis; Atorvastatin; bcl-2-Associated X Protein; Endometriosis; Female; Humans; Inflamm | 2022 |
Low-dose spironolactone ameliorates adipose tissue inflammation and apoptosis in letrozole-induced PCOS rat model.
Topics: Adipose Tissue; Animals; Apoptosis; Female; Humans; Inflammation; Letrozole; Polycystic Ovary Syndro | 2022 |
Low-dose spironolactone combats dyslipidemia and hepatic inflammation by modulating PCSK9 in rat model of polycystic ovarian syndrome.
Topics: Animals; Dyslipidemias; Female; Humans; Inflammation; Letrozole; NLR Family, Pyrin Domain-Containing | 2023 |
Single-cell sequencing provides insights into the landscape of ovary in PCOS and alterations induced by CUMS.
Topics: Animals; Endothelial Cells; Female; Granulosa Cells; Humans; Inflammation; Interferons; Letrozole; P | 2023 |
Butyrate alleviates renal inflammation and fibrosis in a rat model of polycystic ovarian syndrome by suppression of SDF-1.
Topics: Animals; Butyrates; Female; Fibrosis; Humans; Inflammation; Letrozole; Polycystic Ovary Syndrome; Ra | 2023 |
Oxidative stress burden inhibits spermatogenesis in adult male rats: testosterone protective effect.
Topics: Aging; Animals; Biomarkers; Body Weight; Estradiol; Follicle Stimulating Hormone; Grape Seed Extract | 2018 |
Spinal Sigma-1 Receptor-mediated Dephosphorylation of Astrocytic Aromatase Plays a Key Role in Formalin-induced Inflammatory Nociception.
Topics: Animals; Aromatase; Aromatase Inhibitors; Astrocytes; Calcineurin; Formaldehyde; Glial Fibrillary Ac | 2018 |
Steroidal and non-steroidal third-generation aromatase inhibitors induce pain-like symptoms via TRPA1.
Topics: Anastrozole; Androstadienes; Animals; Aromatase Inhibitors; Behavior, Animal; Calcium; Calcium Chann | 2014 |
Dual suppression of estrogenic and inflammatory activities for targeting of endometriosis.
Topics: Animals; Anti-Inflammatory Agents; Cell Survival; Cells, Cultured; Disease Models, Animal; Disease P | 2015 |
Letrozole vs estradiol valerate induced PCOS in rats: glycemic, oxidative and inflammatory status assessment.
Topics: Animals; Antioxidants; Blood Glucose; Blotting, Western; Enzyme-Linked Immunosorbent Assay; Estradio | 2016 |
Role of oxidative stress and low-grade inflammation in letrozole-induced polycystic ovary syndrome in the rat.
Topics: Animals; Aromatase Inhibitors; C-Reactive Protein; Female; Gene Expression Regulation; Inflammation; | 2016 |
Central leptin resistance and hypothalamic inflammation are involved in letrozole-induced polycystic ovary syndrome rats.
Topics: Animals; Body Weight; Eating; Female; Hypothalamus; Inflammation; Leptin; Letrozole; Nitriles; Ovary | 2016 |