Page last updated: 2024-10-30

letrozole and Infertility, Female

letrozole has been researched along with Infertility, Female in 207 studies

Infertility, Female: Diminished or absent ability of a female to achieve conception.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the efficacy of combination treatment of letrozole and clomiphene citrate (CC) in comparison to that of letrozole alone to induce ovulation in infertile women with polycystic ovary syndrome (PCOS)."9.69A triple-blind, randomized controlled trial, comparing combined letrozole and clomiphene versus only letrozole for ovulation induction in women with polycystic ovarian syndrome. ( Hota, S; Kalidoss, VK; Panda, SR; Sharmila, V, 2023)
"We conducted a prospective randomised controlled trial to explore the efficacy of clomiphene citrate (CC) and Letrozole (LTZ) for improving fecundity in infertile women with minimal to mild endometriosis after operative laparoscopy."9.51Ovulation induction with clomiphene citrate or letrozole following laparoscopy in infertile women with minimal to mild endometriosis: a prospective randomised controlled trial. ( Chen, H; Fu, J; Huang, W; Liu, D; Wang, Q; Yang, S; Zhou, L, 2022)
"To estimate the effect of letrozole and clomiphene citrate in women with infertility and polycystic ovarian syndrome (PCOS)."9.41Letrozole Compared With Clomiphene Citrate for Polycystic Ovarian Syndrome: A Systematic Review and Meta-analysis. ( Geng, Y; Hu, R; Huang, Y; Li, F; Liu, Z; Song, Y; Zhang, M, 2023)
"To compare the efficacy of letrozole and clomiphene citrate (CC) for ovulation induction in infertile women with polycystic ovarian syndrome (PCOS)."9.41Letrozole versus clomiphene citrate for ovulation induction in anovulatory women with polycystic ovarian syndrome: A randomized controlled trial. ( Bansal, S; Goyal, M; Sharma, C; Shekhar, S, 2021)
"To compare the effects of letrozole and human menopausal gonadotropin (HMG) in the treatment of patients with polycystic ovary syndrome (PCOS) resistant to clomiphene citrate (CC)."9.34Letrozole and human menopausal gonadotropin for ovulation induction in clomiphene resistance polycystic ovary syndrome patients: A randomized controlled study. ( Chen, L; Hong, T; Huang, X; Jiang, F; Shi, S; Zhuang, Y, 2020)
" We have designed a multicenter randomized controlled trial (RCT) to evaluate whether personalized or fixed acupuncture increases the likelihood of live births in infertile women with polycystic ovary syndrome (PCOS) compared with letrozole or placebo letrozole."9.34A multicenter randomized trial of personalized acupuncture, fixed acupuncture, letrozole, and placebo letrozole on live birth in infertile women with polycystic ovary syndrome. ( Gao, X; Hu, M; Hu, R; Hu, Z; Huang, S; Lai, M; Li, J; Li, S; Liang, X; Liu, J; Ma, H; Ng, EHY; Qiao, J; Quan, K; Shang, H; Stener-Victorin, E; Wang, C; Wang, X; Wen, Q; Wen, X; Xia, T; Zheng, Y, 2020)
"Fertility preservation (FP) protocols in case of breast cancer (BC) include mature oocyte cryopreservation following letrozole associated controlled ovarian hyperstimulation (Let-COH)."9.30Letrozole-associated controlled ovarian hyperstimulation in breast cancer patients versus conventional controlled ovarian hyperstimulation in infertile patients: assessment of oocyte quality related biomarkers. ( De Maertelaer, V; Dechène, J; Delbaere, A; Demeestere, I; Devreker, F; Gervy, C; Goldrat, O; Gonzalez-Merino, E; Van Den Steen, G, 2019)
"To evaluate whether a combination of letrozole and clomiphene citrate (CC) results in higher ovulation rates than letrozole alone in infertile women with polycystic ovary syndrome (PCOS)."9.30A randomized controlled trial of combination letrozole and clomiphene citrate or letrozole alone for ovulation induction in women with polycystic ovary syndrome. ( Kresowik, JD; Mejia, RB; Summers, KM; Van Voorhis, BJ, 2019)
"The purpose is a comparison of effectiveness of myo-inositol and metformin in infertile women with polycystic ovary syndrome (PCOS) treated with letrozole."9.30The effectiveness of inositol and metformin on infertile polycystic ovary syndrome women with resistant to letrozole. ( Bazarganipour, F; Kutenaee, MA; Pourghasem, S; Taghavi, SA, 2019)
"This is a randomized non-blinded controlled trial study that included 80 infertile females with polycystic ovarian syndrome receiving a standard dose of either clomiphene citrate or letrozole on day 2 of the cycle."9.30Impact of letrozole versus clomiphene citrate on endometrial receptivity in Iraqi women with polycystic ovarian syndrome. ( Al-Aubaidy, H; Al-Obaidi, MT; Al-Saadi, WI; Al-Wasiti, EAR; Ali, ZH, 2019)
"To compare the therapeutic efficacy of clomiphene citrate (CC) and letrozole (LE) on ovulation, pregnancy, and live birth in women with polycystic ovary syndrome (PCOS); and to ensure if LE can replace CC as the first-line therapy for ovulation induction in these women."9.24Comparison of clomiphene citrate and letrozole for ovulation induction in women with polycystic ovary syndrome: a prospective randomized trial. ( Feng, G; Fu, J; Huang, W; Liu, C; Liu, D; Tan, J; Wang, Q; Yang, S, 2017)
"Letrozole appears to improve live birth rates and pregnancy rates in infertile women with anovulatory PCOS, compared to SERMs, when used for ovulation induction, followed by intercourse."9.22Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome. ( Farquhar, C; Franik, S; Kiesel, L; Kremer, JA; Le, QK, 2022)
"To investigate the optimal ovulation induction with the combination of combining letrozole(LE),clomiphene citrate (CC),and human menopausal gonadotropin (HMG) in polycystic ovary syndrome(PCOS) patients resistant to CC or LE."9.22[Optimal Ovulation Induction in Polycystic Ovary Syndrome Resistant to Clomiphene Citrate or Letrozole.] ( Chen, Y; Zhang, D, 2016)
"To examine the efficacy of clomifene citrate, metformin, and pioglitazone versus letrozole, metformin, and pioglitazone among women with polycystic ovary syndrome (PCOS) resistant to clomifene citrate."9.22A randomized controlled trial of clomifene citrate, metformin, and pioglitazone versus letrozole, metformin, and pioglitazone for clomifene-citrate-resistant polycystic ovary syndrome. ( Abdel Moety, G; Al Mohammady, M; El-khayat, W; Hamed, D, 2016)
"To study whether a combination of berberine and letrozole results in higher live births than letrozole alone in infertile women with polycystic ovary syndrome (PCOS)."9.22Randomized controlled trial of letrozole, berberine, or a combination for infertility in the polycystic ovary syndrome. ( Liang, RN; Liu, JP; Ma, HX; Ng, EH; Shao, XG; Wang, YY; Wu, XK; Xue, HY, 2016)
"Clomiphene is the current first-line infertility treatment in women with the polycystic ovary syndrome, but aromatase inhibitors, including letrozole, might result in better pregnancy outcomes."9.19Letrozole versus clomiphene for infertility in the polycystic ovary syndrome. ( Alvero, R; Baker, V; Barnhart, KT; Bates, GW; Brzyski, RG; Casson, P; Christman, GM; Coutifaris, C; Diamond, MP; Eisenberg, E; Haisenleder, DJ; Huang, H; Krawetz, SA; Legro, RS; Lucidi, S; Ohl, D; Santoro, N; Schlaff, WD; Snyder, P; Trussell, JC; Usadi, R; Yan, Q; Zhang, H, 2014)
"The aim of the present study was to investigate the clinical value of low‑dose aspirin in combination with Tiao Jing Cu Yun pills in patients with polycystic ovary syndrome (PCOS) by measuring follicular peripheral blood flow parameters and the clinical efficacy."9.19Effects of combining low‑dose aspirin with a Chinese patent medicine on follicular blood flow and pregnancy outcome. ( Du, B; Jiang, X; Ma, M; Shi, L; Zhang, Q; Zhao, Y; Zhou, L, 2014)
"To investigate the effect of letrozole in decreasing the early-stage ovarian hyperstimulation syndrome (OHSS) occurrence during the luteal phase for patients of OHSS high-risk after oocyte retrieval."9.19[Relationship between letrozole administration during the luteal phase after oocyte retrieval and the early-stage ovarian hyperstimulation syndrome oocurrence]. ( Cui, S; He, Q; Li, H; Xu, J; Zhang, C, 2014)
" In this study, we used a combination of letrozole and clomiphene in patients resistant to both drugs individually, and studied the effects of this combination in ovulation and pregnancy in resistant PCOS patients."9.17Combined letrozole and clomiphene versus letrozole and clomiphene alone in infertile patients with polycystic ovary syndrome. ( Dehghan, M; Ghasemi-Rad, M; Hajishafiha, M; Kiarang, N; Sadegh-Asadi, N; Shayegh, SN, 2013)
"To compare the hormonal-metabolic profiles and reproductive outcomes between women receiving metformin plus letrozole and women undergoing bilateral ovarian drilling in clomiphene citrate (CC)-resistant women with polycystic ovary syndrome (PCOS)."9.17Efficacy of combined metformin-letrozole in comparison with bilateral ovarian drilling in clomiphene-resistant infertile women with polycystic ovarian syndrome. ( Abd Elgafor, I, 2013)
"The objective of this study was to compare the efficacy of letrozole versus clomiphene citrate as an ovulation induction drug in polycystic ovarian syndrome (PCOS) patients of Indian origin."9.16Comparison of efficacy of letrozole and clomiphene citrate in ovulation induction in Indian women with polycystic ovarian syndrome. ( Banerjee Ray, P; Chakraborti, PS; Ray, A, 2012)
"To evaluate pregnancy rates with letrozole and clomiphene citrate (CC) alone for superovulation in an intrauterine insemination program for women with recently surgically treated minimal to mild endometriosis."9.16Randomized comparison of superovulation with letrozole vs. clomiphene citrate in an IUI program for women with recently surgically treated minimal to mild endometriosis. ( Abd Elaal, I; Abu Hashim, H; El Rakhawy, M, 2012)
"To compare the role of an aromatase inhibitor (letrozole) with a GnRH agonist (triptorelin) versus case control on the pregnancy rate and recurrence of symptoms and signs in patients with endometriosis."9.15A comparison of the effect of short-term aromatase inhibitor (letrozole) and GnRH agonist (triptorelin) versus case control on pregnancy rate and symptom and sign recurrence after laparoscopic treatment of endometriosis. ( Alborzi, M; Alborzi, S; Dehbashi, S; Hamedi, B; Omidvar, A, 2011)
"To compare the clinical outcomes of letrozole and laparoscopic ovarian drilling (LOD) in patients with clomiphene-citrate-resistant polycystic ovary syndrome (PCOS)."9.15Reproductive outcome after letrozole versus laparoscopic ovarian drilling for clomiphene-resistant polycystic ovary syndrome. ( Abdellah, MS, 2011)
"The objective of this systematic review was to examine the literature and to compare the effectiveness of letrozole (LE) versus laparoscopic ovarian drilling (LOD) for the induction of ovulation in women with clomiphene citrate (CC)-resistant polycystic ovary syndrome (PCOS)."9.01Letrozole versus laparoscopic ovarian drilling in clomiphene citrate-resistant women with polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials. ( Cheng, G; Hu, S; Wang, Y; Xia, W; Yu, Q; Zhu, C, 2019)
"Letrozole appears to improve live birth and pregnancy rates in subfertile women with anovulatory polycystic ovary syndrome, compared to clomiphene citrate."8.98Aromatase inhibitors (letrozole) for subfertile women with polycystic ovary syndrome. ( Eltrop, SM; Farquhar, C; Franik, S; Kiesel, L; Kremer, JA, 2018)
"The objective of the present systematic review and meta-analysis was to examine the literature and to identify the results of randomized controlled trials (RCTs) comparing the use of letrozole to clomiphene citrate (CC) for ovulation induction in patients with polycystic ovary syndrome (PCOS)."8.91Letrozole versus clomiphene citrate in polycystic ovary syndrome: systematic review and meta-analysis. ( Geber, S; Roque, M; Sampaio, M; Tostes, AC; Valle, M, 2015)
"To evaluate whether extending letrozole (LE) treatment duration could induce ovulation in women with polycystic ovary syndrome (PCOS) who previously failed to ovulate after a 5-day regimen of 5 mg LE daily for at least 1 ovulation induction cycle, defined as "LE resistance"."8.31Extending letrozole treatment duration is effective in inducing ovulation in women with polycystic ovary syndrome and letrozole resistance. ( Fu, Y; Zhu, X, 2023)
"To assess efficacy of adjuvant dexamethasone during letrozole cycles for ovulation induction (OI) in women with letrozole-resistant polycystic ovary syndrome (PCOS)."8.31Ovulation induction with letrozole and dexamethasone in infertile patients with letrozole-resistant polycystic ovary syndrome. ( Babayev, SN; Baumgarten, SC; Neblett, MF; Shenoy, CC, 2023)
" This study was performed to explore the relationship between follicle size, endometrial thickness, and types of ovarian stimulation (Clomiphene citrate/CC vs Letrozole) with biochemical pregnancy rate in women undergone IUI."8.31Association between follicle size, endometrial thickness, and types of ovarian stimulation (Clomiphene citrate and Letrozole) with biochemical pregnancy rate in women undergone intrauterine insemination. ( Krisnadi, SR; Nugrahani, AD; Rachmawati, A; Santoso, SA, 2023)
" Previous studies have shown that administration of letrozole, a non-steroidal aromatase inhibitor for cancer treatment, increased the clinical pregnancy rate in women with endometriosis, but the mechanisms remain to be determined."8.12Letrozole promotes the expression of integrin αvβ3 and HOXA10 in endometrium of endometriosis. ( Li, C; Li, M; Li, R; Wang, L; Zhang, H; Zhang, J, 2022)
"To investigate the efficacy of oral letrozole (LE) starting on day 3 or 5 of the menstrual cycle in patients with polycystic ovary syndrome (PCOS)."8.12Effect of different timing of letrozole initiation on pregnancy outcome in polycystic ovary syndrome. ( Chen, Y; Gao, M; Jin, X; Shi, L; Ye, S; Zhang, Z, 2022)
"We sought to compare the efficacy of the letrozole (LTZ) stair-step protocol with clomiphene citrate (CC) stair-step protocol in the management of 150 mg dose of CC-resistant polycystic ovary syndrome (PCOS) patients."8.02Comparison of the efficacy of letrozole stair-step protocol with clomiphene citrate stair-step protocol in the management of clomiphene citrate-resistant polycystic ovary syndrome patients. ( Oğlak, SC; Sakar, MN, 2021)
"The aim of this study was to compare a combination treatment with CC plus letrozole versus gonadotropins in CC-resistant polycystic ovary syndrome (PCOS) patients with regard to ovulation and clinical pregnancy rate."7.96A comparison between a combination of letrozole and clomiphene citrate versus gonadotropins for ovulation induction in infertile patients with clomiphene citrateresistant polycystic ovary syndrome - a retrospective study. ( Bademkıran, MH; Ege, S; Hançer Çaça, FN; Özçelik, SM; Peker, N; Tahaoğlu, AE, 2020)
"Children of women with polycystic ovary syndrome who conceived with letrozole (LTZ) or clomiphene (CC) in the PPCOS II study or women with unexplained infertility (AMIGOS study) who conceived with LTZ, CC, or gonadotropin (GN)."7.96Pregnancy registry: three-year follow-up of children conceived from letrozole, clomiphene, or gonadotropins. ( Alvero, R; Baker, V; Barnhart, KT; Casson, P; Cedars, MI; Christman, GM; Coutifaris, C; Coward, RM; Diamond, MP; Dodson, WC; Eisenberg, E; Estes, SJ; Hansen, KR; Huang, H; Krawetz, SA; Kunselman, A; Legro, RS; Robinson, R; Rosen, RM; Santoro, N; Schlaff, WD; Stetter, C; Trussell, JC; Usadi, R; Zhang, H, 2020)
"To investigate whether live birth rate (LBR) following frozen-thawed embryo transfer in letrozole-stimulated cycles (L-FET) differs from LBR after artificial-cycle frozen-thawed embryos transfers (AC-FET) in women with polycystic ovary syndrome (PCOS)."7.91Letrozole use during frozen embryo transfer cycles in women with polycystic ovary syndrome. ( Chen, Q; Fan, Y; Kuang, Y; Liu, H; Mao, X; Wang, Y; Xiao, Y; Zhang, J, 2019)
"We compared sonographic findings, fertility results, pregnancy complications and congenital anomalies in two groups of women treated with letrozole and CC."7.88Comparison of the pregnancy outcomes and the incidence of fetal congenital abnormalities in infertile women treated with letrozole and clomiphene citrate. ( Akbari Sene, A; Ashrafi, M; Ghorbani, S, 2018)
"BACKGROUND Women with polycystic ovary syndrome (PCOS) undergoing in vitro fertilization (IVF) are given letrozole before a trigger injection of human chorionic gonadotropin (hCG) to lower estrogen (E2) levels, but can experience ovarian hyperstimulation syndrome (OHSS)."7.88A Retrospective Study of Letrozole Treatment Prior to Human Chorionic Gonadotropin in Women with Polycystic Ovary Syndrome Undergoing In Vitro Fertilization at Risk of Ovarian Hyperstimulation Syndrome. ( Chen, Y; Hao, C; Yang, T; Zhao, J, 2018)
"This retrospective study investigated the efficacy and safety of letrozole for patients with polycystic ovary syndrome (PCOS)."7.88Letrozole for patients with polycystic ovary syndrome: A retrospective study. ( Guang, HJ; Li, F; Shi, J, 2018)
"Variable dose letrozole-FSH protocol can maintain lower peak estradiol levels and reduce estrogen exposure after breast cancer operation and chemotherapy."7.83Twin delivery after IVF-ET with variable dose letrozole-FSH protocol of lower estradiol in a patient previously treated for breast cancer: a case report. ( Diao, H; Hu, GZ; Zhang, CJ; Zhang, Y, 2016)
"To investigate the safety and feasibility of performing two consecutive ovarian stimulation cycles with the use of letrozole protocol for fertility preservation in breast cancer patients."7.79Safety and feasibility of performing two consecutive ovarian stimulation cycles with the use of letrozole-gonadotropin protocol for fertility preservation in breast cancer patients. ( Bedoschi, G; Moy, F; Oktay, K; Turan, V, 2013)
"To determine the effect of intravaginal micronized P on pregnancy rates in clomiphene citrate and letrozole ovulation induction cycles in women with polycystic ovary syndrome (PCOS)."7.76Luteal support with intravaginal progesterone increases clinical pregnancy rates in women with polycystic ovary syndrome using letrozole for ovulation induction. ( Aubuchon, M; Khabbaz, M; Montville, CP; Thomas, MA; Williams, DB, 2010)
"To investigate the effect of two different doses of letrozole in promoting ovulation in infertile women with polycystic ovarian syndrome (PCOS)."7.74[Effect of two different doses of letrozole in promoting ovulation in infertile women with polycystic ovarian syndrome]. ( Li, H; Quan, S; Song, YL; Xing, FQ; Yang, MQ, 2008)
"Letrozole induction of ovulation in clomiphene citrate-resistant women with polycystic ovary syndrome is associated with an ovulation rate of 54."7.73Letrozole induction of ovulation in women with clomiphene citrate-resistant polycystic ovary syndrome may not depend on the period of infertility, the body mass index, or the luteinizing hormone/follicle-stimulating hormone ratio. ( Eldosoky, M; Elnashar, A; Fouad, H; Saeid, N, 2006)
"Letrozole, with lower incidences of LUF, is more effective than clomiphene citrate for the induction of ovulation in IUI cycles."6.80Effects of Letrozole-HMG and Clomiphene-HMG on Incidence of Luteinized Unruptured Follicle Syndrome in Infertile Women Undergoing Induction Ovulation and Intrauterine Insemination: A Randomised Trial. ( Akbari Asbagh, F; Azmoodeh, A; Ghaseminejad, A; Hamzehgardeshi, Z; Pejman Manesh, M, 2015)
" The aim of the study was to evaluate the effectiveness and efficacy of letrozole and clomiphene citrate (CC) combined with human menopausal gonadotropin (HMG) in CC-resistant infertile women with PCOS."6.80Use of letrozole and clomiphene citrate combined with gonadotropins in clomiphene-resistant infertile women with polycystic ovary syndrome: a prospective study. ( Liu, S; Lu, X; Mao, H; Xi, W; Xue, X; Yang, Y, 2015)
"letrozole for 5 treatment cycles (or approximately up to 25 weeks)."6.77The Pregnancy in Polycystic Ovary Syndrome II (PPCOS II) trial: rationale and design of a double-blind randomized trial of clomiphene citrate and letrozole for the treatment of infertility in women with polycystic ovary syndrome. ( Brzyski, RG; Casson, PR; Christman, GM; Coutifaris, C; Diamond, MP; Eisenberg, E; Kunselman, AR; Legro, RS; Santoro, N; Schlaff, WD; Taylor, HS; Zhang, H, 2012)
"Polycystic ovary syndrome is a common disease that is closely related to ovulation dysfunction and 7% of women of childbearing age are afflicted with it."6.77Comparison of the effects of letrozole and clomiphene citrate for ovulation induction in infertile women with polycystic ovary syndrome. ( Nahid, L; Sirous, K, 2012)
" This study aimed to investigate the effect of letrozole and metformin combined with targeted nursing on ovarian function, LH, and FSH in infertile patients with PCOS."5.72The Effects of Letrozole and Metformin Combined with Targeted Nursing Care on Ovarian Function, LH, and FSH in Infertile Patients with Polycystic Ovary Syndrome. ( Jiang, S; Li, R; Sheng, Y; Tang, T; Xu, H, 2022)
"To evaluate the efficacy of combination treatment of letrozole and clomiphene citrate (CC) in comparison to that of letrozole alone to induce ovulation in infertile women with polycystic ovary syndrome (PCOS)."5.69A triple-blind, randomized controlled trial, comparing combined letrozole and clomiphene versus only letrozole for ovulation induction in women with polycystic ovarian syndrome. ( Hota, S; Kalidoss, VK; Panda, SR; Sharmila, V, 2023)
"Retrospective cohort study of 118 breast cancer patients undergoing fertility preservation treatment between 2008 and 2018."5.62Effects of letrozole or tamoxifen coadministered with a standard stimulation protocol on fertility preservation among breast cancer patients. ( Almog, B; Azem, F; Cohen, Y; Fouks, Y; Kalma, Y; Shulman, Y, 2021)
"Letrozole was associated with significantly higher clinical pregnancy (38."5.62Letrozole as first-line drug for ovulation induction in treatment-naïve infertile polycystic ovarian syndrome women. ( Joseph, T; Kamath, MS; Kunjummen, AT; Rebekah, G; Waanbah, BD, 2021)
"Letrozole is a risk factor for worse oocyte morphology."5.56The impact of letrozole administration on oocyte morphology in breast cancer patients undergoing fertility preservation. ( Alves, VR; Bercaire, LMN; Cavagna, F; Cavagna, M; Donadio, NF; Dzik, A; Gebrim, LH; Nahas, EAP; Portela, R; Rocha, AR; Santos, TBB, 2020)
"Clomiphene citrate (CC) and letrozole are ovulatory stimulants that, despite high ovulation rates, achieve low pregnancy rates."5.51The Effect of Clomiphene Citrate and Letrozole in Apoptotic Pathways and Cell Cycle in Human Primary Cumulus Cells and the Protective Effect of Estradiol. ( Aguiar, LPT; Coelho, SS; Del Puerto, HL; Ferreira, MCF; Moraes, LM; Oliveira, GG; Oliveira, RM; Prazeres, PHDM; Silveira, CO; Souza, FHS, 2022)
"To examine the effect of letrozole on oocyte quality and pregnancy outcome in assisted reproductive technology (ART)."5.51The impact of letrozole on oocyte quality in assisted reproductive technology (ART); a randomized double-blind clinical trial. ( Amanpour, S; Bandarian, F; Bandarian, M; Hossein Rashidi, B; Shahrokh Tehraninejad, E, 2022)
"We conducted a prospective randomised controlled trial to explore the efficacy of clomiphene citrate (CC) and Letrozole (LTZ) for improving fecundity in infertile women with minimal to mild endometriosis after operative laparoscopy."5.51Ovulation induction with clomiphene citrate or letrozole following laparoscopy in infertile women with minimal to mild endometriosis: a prospective randomised controlled trial. ( Chen, H; Fu, J; Huang, W; Liu, D; Wang, Q; Yang, S; Zhou, L, 2022)
"Letrozole-treated patients required a significantly lower amount of gonadotropins units (p < 0."5.48Mild ovarian stimulation with letrozole plus fixed dose human menopausal gonadotropin prior to IVF/ICSI for infertile non-obese women with polycystic ovarian syndrome being pre-treated with metformin: a pilot study. ( Cantatore, C; Caringella, AM; Caroppo, E; D'Amato, G; Palini, S; Stanziano, A, 2018)
"To estimate the effect of letrozole and clomiphene citrate in women with infertility and polycystic ovarian syndrome (PCOS)."5.41Letrozole Compared With Clomiphene Citrate for Polycystic Ovarian Syndrome: A Systematic Review and Meta-analysis. ( Geng, Y; Hu, R; Huang, Y; Li, F; Liu, Z; Song, Y; Zhang, M, 2023)
"To compare the efficacy of letrozole and clomiphene citrate (CC) for ovulation induction in infertile women with polycystic ovarian syndrome (PCOS)."5.41Letrozole versus clomiphene citrate for ovulation induction in anovulatory women with polycystic ovarian syndrome: A randomized controlled trial. ( Bansal, S; Goyal, M; Sharma, C; Shekhar, S, 2021)
"Letrozole is a potent, nonsteroidal, aromatase inhibitor, originally used for postmenopausal breast cancer therapy, at present its only registered indication."5.37Use of the aromatase inhibitor letrozole for ovulation induction in women with polycystic ovarian syndrome. ( Casper, RF; Mitwally, MF, 2011)
"To compare the effects of letrozole and human menopausal gonadotropin (HMG) in the treatment of patients with polycystic ovary syndrome (PCOS) resistant to clomiphene citrate (CC)."5.34Letrozole and human menopausal gonadotropin for ovulation induction in clomiphene resistance polycystic ovary syndrome patients: A randomized controlled study. ( Chen, L; Hong, T; Huang, X; Jiang, F; Shi, S; Zhuang, Y, 2020)
" We have designed a multicenter randomized controlled trial (RCT) to evaluate whether personalized or fixed acupuncture increases the likelihood of live births in infertile women with polycystic ovary syndrome (PCOS) compared with letrozole or placebo letrozole."5.34A multicenter randomized trial of personalized acupuncture, fixed acupuncture, letrozole, and placebo letrozole on live birth in infertile women with polycystic ovary syndrome. ( Gao, X; Hu, M; Hu, R; Hu, Z; Huang, S; Lai, M; Li, J; Li, S; Liang, X; Liu, J; Ma, H; Ng, EHY; Qiao, J; Quan, K; Shang, H; Stener-Victorin, E; Wang, C; Wang, X; Wen, Q; Wen, X; Xia, T; Zheng, Y, 2020)
"Fertility preservation (FP) protocols in case of breast cancer (BC) include mature oocyte cryopreservation following letrozole associated controlled ovarian hyperstimulation (Let-COH)."5.30Letrozole-associated controlled ovarian hyperstimulation in breast cancer patients versus conventional controlled ovarian hyperstimulation in infertile patients: assessment of oocyte quality related biomarkers. ( De Maertelaer, V; Dechène, J; Delbaere, A; Demeestere, I; Devreker, F; Gervy, C; Goldrat, O; Gonzalez-Merino, E; Van Den Steen, G, 2019)
"To evaluate whether a combination of letrozole and clomiphene citrate (CC) results in higher ovulation rates than letrozole alone in infertile women with polycystic ovary syndrome (PCOS)."5.30A randomized controlled trial of combination letrozole and clomiphene citrate or letrozole alone for ovulation induction in women with polycystic ovary syndrome. ( Kresowik, JD; Mejia, RB; Summers, KM; Van Voorhis, BJ, 2019)
"The purpose is a comparison of effectiveness of myo-inositol and metformin in infertile women with polycystic ovary syndrome (PCOS) treated with letrozole."5.30The effectiveness of inositol and metformin on infertile polycystic ovary syndrome women with resistant to letrozole. ( Bazarganipour, F; Kutenaee, MA; Pourghasem, S; Taghavi, SA, 2019)
"This is a randomized non-blinded controlled trial study that included 80 infertile females with polycystic ovarian syndrome receiving a standard dose of either clomiphene citrate or letrozole on day 2 of the cycle."5.30Impact of letrozole versus clomiphene citrate on endometrial receptivity in Iraqi women with polycystic ovarian syndrome. ( Al-Aubaidy, H; Al-Obaidi, MT; Al-Saadi, WI; Al-Wasiti, EAR; Ali, ZH, 2019)
"To compare the therapeutic efficacy of clomiphene citrate (CC) and letrozole (LE) on ovulation, pregnancy, and live birth in women with polycystic ovary syndrome (PCOS); and to ensure if LE can replace CC as the first-line therapy for ovulation induction in these women."5.24Comparison of clomiphene citrate and letrozole for ovulation induction in women with polycystic ovary syndrome: a prospective randomized trial. ( Feng, G; Fu, J; Huang, W; Liu, C; Liu, D; Tan, J; Wang, Q; Yang, S, 2017)
" We included randomized controlled trials (RCTs) comparing IUI-OS with gonadotrophins, letrozole and CC among couples with unexplained infertility."5.22Ovarian stimulation strategies for intrauterine insemination in couples with unexplained infertility: a systematic review and individual participant data meta-analysis. ( Cohlen, BJ; D'Hooghe, TM; Danhof, NA; Dankert, T; Diamond, MP; Erdem, M; Legro, RS; Mochtar, MH; Mol, BWJ; Peeraer, K; Showell, M; Thyagaraju, C; van Eekelen, R; van Wely, M; Wang, R; Wessel, JA, 2022)
"Letrozole appears to improve live birth rates and pregnancy rates in infertile women with anovulatory PCOS, compared to SERMs, when used for ovulation induction, followed by intercourse."5.22Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome. ( Farquhar, C; Franik, S; Kiesel, L; Kremer, JA; Le, QK, 2022)
"To investigate the optimal ovulation induction with the combination of combining letrozole(LE),clomiphene citrate (CC),and human menopausal gonadotropin (HMG) in polycystic ovary syndrome(PCOS) patients resistant to CC or LE."5.22[Optimal Ovulation Induction in Polycystic Ovary Syndrome Resistant to Clomiphene Citrate or Letrozole.] ( Chen, Y; Zhang, D, 2016)
"To examine the efficacy of clomifene citrate, metformin, and pioglitazone versus letrozole, metformin, and pioglitazone among women with polycystic ovary syndrome (PCOS) resistant to clomifene citrate."5.22A randomized controlled trial of clomifene citrate, metformin, and pioglitazone versus letrozole, metformin, and pioglitazone for clomifene-citrate-resistant polycystic ovary syndrome. ( Abdel Moety, G; Al Mohammady, M; El-khayat, W; Hamed, D, 2016)
"To study whether a combination of berberine and letrozole results in higher live births than letrozole alone in infertile women with polycystic ovary syndrome (PCOS)."5.22Randomized controlled trial of letrozole, berberine, or a combination for infertility in the polycystic ovary syndrome. ( Liang, RN; Liu, JP; Ma, HX; Ng, EH; Shao, XG; Wang, YY; Wu, XK; Xue, HY, 2016)
"Clomiphene is the current first-line infertility treatment in women with the polycystic ovary syndrome, but aromatase inhibitors, including letrozole, might result in better pregnancy outcomes."5.19Letrozole versus clomiphene for infertility in the polycystic ovary syndrome. ( Alvero, R; Baker, V; Barnhart, KT; Bates, GW; Brzyski, RG; Casson, P; Christman, GM; Coutifaris, C; Diamond, MP; Eisenberg, E; Haisenleder, DJ; Huang, H; Krawetz, SA; Legro, RS; Lucidi, S; Ohl, D; Santoro, N; Schlaff, WD; Snyder, P; Trussell, JC; Usadi, R; Yan, Q; Zhang, H, 2014)
"The aim of the present study was to investigate the clinical value of low‑dose aspirin in combination with Tiao Jing Cu Yun pills in patients with polycystic ovary syndrome (PCOS) by measuring follicular peripheral blood flow parameters and the clinical efficacy."5.19Effects of combining low‑dose aspirin with a Chinese patent medicine on follicular blood flow and pregnancy outcome. ( Du, B; Jiang, X; Ma, M; Shi, L; Zhang, Q; Zhao, Y; Zhou, L, 2014)
"To investigate the effect of letrozole in decreasing the early-stage ovarian hyperstimulation syndrome (OHSS) occurrence during the luteal phase for patients of OHSS high-risk after oocyte retrieval."5.19[Relationship between letrozole administration during the luteal phase after oocyte retrieval and the early-stage ovarian hyperstimulation syndrome oocurrence]. ( Cui, S; He, Q; Li, H; Xu, J; Zhang, C, 2014)
" In this study, we used a combination of letrozole and clomiphene in patients resistant to both drugs individually, and studied the effects of this combination in ovulation and pregnancy in resistant PCOS patients."5.17Combined letrozole and clomiphene versus letrozole and clomiphene alone in infertile patients with polycystic ovary syndrome. ( Dehghan, M; Ghasemi-Rad, M; Hajishafiha, M; Kiarang, N; Sadegh-Asadi, N; Shayegh, SN, 2013)
"To compare the hormonal-metabolic profiles and reproductive outcomes between women receiving metformin plus letrozole and women undergoing bilateral ovarian drilling in clomiphene citrate (CC)-resistant women with polycystic ovary syndrome (PCOS)."5.17Efficacy of combined metformin-letrozole in comparison with bilateral ovarian drilling in clomiphene-resistant infertile women with polycystic ovarian syndrome. ( Abd Elgafor, I, 2013)
"The objective of this study was to compare the efficacy of letrozole versus clomiphene citrate as an ovulation induction drug in polycystic ovarian syndrome (PCOS) patients of Indian origin."5.16Comparison of efficacy of letrozole and clomiphene citrate in ovulation induction in Indian women with polycystic ovarian syndrome. ( Banerjee Ray, P; Chakraborti, PS; Ray, A, 2012)
"To evaluate pregnancy rates with letrozole and clomiphene citrate (CC) alone for superovulation in an intrauterine insemination program for women with recently surgically treated minimal to mild endometriosis."5.16Randomized comparison of superovulation with letrozole vs. clomiphene citrate in an IUI program for women with recently surgically treated minimal to mild endometriosis. ( Abd Elaal, I; Abu Hashim, H; El Rakhawy, M, 2012)
"Letrozole has beneficial effect on endometrium, an action that may improve the implantation and pregnancy rates in women with unexplained infertility."5.16Letrozole versus clomiphene citrate for superovulation in Egyptian women with unexplained infertility: a randomized controlled trial. ( Abdel-Azeem, AA; Ibrahim, MI; Moustafa, RA, 2012)
"To compare the role of an aromatase inhibitor (letrozole) with a GnRH agonist (triptorelin) versus case control on the pregnancy rate and recurrence of symptoms and signs in patients with endometriosis."5.15A comparison of the effect of short-term aromatase inhibitor (letrozole) and GnRH agonist (triptorelin) versus case control on pregnancy rate and symptom and sign recurrence after laparoscopic treatment of endometriosis. ( Alborzi, M; Alborzi, S; Dehbashi, S; Hamedi, B; Omidvar, A, 2011)
"To compare the clinical outcomes of letrozole and laparoscopic ovarian drilling (LOD) in patients with clomiphene-citrate-resistant polycystic ovary syndrome (PCOS)."5.15Reproductive outcome after letrozole versus laparoscopic ovarian drilling for clomiphene-resistant polycystic ovary syndrome. ( Abdellah, MS, 2011)
"The aim of this study was to determine the risks of congenital malformations and pregnancy loss with letrozole compared with clomiphene primarily, and with other fertility drugs and natural conception."5.12Risk of foetal harm with letrozole use in fertility treatment: a systematic review and meta-analysis. ( Achilli, C; Bhide, P; Coomarasamy, A; Legro, RS; Pundir, J; Rombauts, L; Sabatini, L; Teede, H; Thangaratinam, S; Zamora, J, 2021)
"Adding metformin to clomiphene citrate in clomiphene-resistant polycystic ovary syndrome (PCOS) patients increases ovulatory response."5.12Efficacy of combined metformin-letrozole in comparison with metformin-clomiphene citrate in clomiphene-resistant infertile women with polycystic ovarian disease. ( Ansari, Sh; Bagheri, M; Sohrabvand, F, 2006)
"To compare the effectiveness of letrozole and clomiphene citrate (CC) in ovulatory patients with borderline male factor infertility, early stage endometriosis, and unexplained infertility."5.12Letrozole vs. clomiphene citrate in patients with ovulatory infertility. ( Ayoğlu, F; Barut, A; Bayar, U; Kaya, E; Ozcan, O; Tanriverdi, HA, 2006)
"To compare the use of the aromatase inhibitor, letrozole, in conjunction with follicle-stimulating hormone (FSH) injection, and FSH alone for controlled ovarian hyperstimulation (COH) in patients with polycystic ovarian syndrome (PCOS) or ovulatory infertility."5.11Aromatase inhibition reduces the dose of gonadotropin required for controlled ovarian hyperstimulation. ( Casper, RF; Mitwally, MF, 2004)
"Superovulation and IUI with letrozole and CC are associated with similar pregnancy rates, but the miscarriage rate is higher with CC."5.11A randomized trial of letrozole versus clomiphene citrate in women undergoing superovulation. ( Al-Fozan, H; Al-Khadouri, M; Tan, SL; Tulandi, T, 2004)
" With letrozole treatment in the same patients with PCOS, ovulation occurred in 9 of 12 cycles (75%) and pregnancy was achieved in 3 patients (25%)."5.09Use of an aromatase inhibitor for induction of ovulation in patients with an inadequate response to clomiphene citrate. ( Casper, RF; Mitwally, MF, 2001)
"Letrozole is a targeted aromatase inhibitor which has primarily been used in post-menopausal women with breast cancer."5.05A review of the physiology behind letrozole applications in infertility: are current protocols optimal? ( Brown, SE; Rose, BI, 2020)
"In women with PCOS, letrozole improves live birth and clinical pregnancy rates and reduces time-to-pregnancy compared to CC and therefore can be recommended as the preferred first-line treatment for women with PCOS and infertility."5.01First-line ovulation induction for polycystic ovary syndrome: an individual participant data meta-analysis. ( Amer, SA; Bhattacharya, S; Bordewijk, EM; Falbo, A; Federica, G; Gao, J; Homburg, R; Huang, W; Johnson, NP; Kar, S; König, TE; Legro, RS; Li, W; Lord, J; Mol, BW; Moll, E; Morin-Papunen, L; Nazik, H; Norman, RJ; Özmen, Ü; Palomba, S; Sahin, Y; van Wely, M; Vegetti, W; Wang, R; Williams, CD; Wu, X; Zhang, H, 2019)
"The objective of this systematic review was to examine the literature and to compare the effectiveness of letrozole (LE) versus laparoscopic ovarian drilling (LOD) for the induction of ovulation in women with clomiphene citrate (CC)-resistant polycystic ovary syndrome (PCOS)."5.01Letrozole versus laparoscopic ovarian drilling in clomiphene citrate-resistant women with polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials. ( Cheng, G; Hu, S; Wang, Y; Xia, W; Yu, Q; Zhu, C, 2019)
"To estimate the clinical effectiveness, as determined by positive pregnancy test, of letrozole compared with clomiphene citrate for ovarian stimulation in patients with unexplained infertility."5.01Letrozole Compared With Clomiphene Citrate for Unexplained Infertility: A Systematic Review and Meta-analysis. ( Bedrick, BS; Colditz, GA; Eskew, AM; Hardi, A; Jungheim, ES; Stoll, CRT; Tuuli, MG, 2019)
"Letrozole appears to improve live birth and pregnancy rates in subfertile women with anovulatory polycystic ovary syndrome, compared to clomiphene citrate."4.98Aromatase inhibitors (letrozole) for subfertile women with polycystic ovary syndrome. ( Eltrop, SM; Farquhar, C; Franik, S; Kiesel, L; Kremer, JA, 2018)
"Randomised controlled trials comparing eight ovulation induction treatments in women with WHO group II anovulation: clomiphene, letrozole, metformin, clomiphene and metformin combined, tamoxifen, gonadotropins, laparoscopic ovarian drilling, and placebo or no treatment."4.95Treatment strategies for women with WHO group II anovulation: systematic review and network meta-analysis ( Bhattacharya, S; Costello, MF; Johnson, NP; Kim, BV; Legro, RS; Mol, BW; Ng, EH; Norman, RJ; van Wely, M; Wang, R; Zhang, H, 2017)
"The objective of the present systematic review and meta-analysis was to examine the literature and to identify the results of randomized controlled trials (RCTs) comparing the use of letrozole to clomiphene citrate (CC) for ovulation induction in patients with polycystic ovary syndrome (PCOS)."4.91Letrozole versus clomiphene citrate in polycystic ovary syndrome: systematic review and meta-analysis. ( Geber, S; Roque, M; Sampaio, M; Tostes, AC; Valle, M, 2015)
"Letrozole appears to improve live birth and pregnancy rates in subfertile women with anovulatory PCOS, compared to clomiphene citrate."4.90Aromatase inhibitors for subfertile women with polycystic ovary syndrome. ( Farquhar, C; Franik, S; Kremer, JA; Nelen, WL, 2014)
"The objective of this study is to investigate and compare the effectiveness of letrozole and clomiphene citrate for improving fertility outcomes, including pregnancy rate, miscarriage rate, multiple pregnancy rate, and incidence rate of adverse events, number of dominant follicles, endometrial thickness at hCG day and serum E2 on hCG day."4.90Letrozole versus clomiphene citrate for unexplained infertility: a systematic review and meta-analysis. ( Chen, W; Lang, J; Liu, A; Zheng, C, 2014)
" The Pregnancy in PCOS trial II will determine the safety and efficacy of clomiphene citrate compared to letrozole, in achieving live birth in infertile women with PCOS."4.88Reproductive impact of polycystic ovary syndrome. ( Legro, RS; Usadi, RS, 2012)
"Ovulation induction with letrozole is associated with an ovulation rate of 70%-84% and a pregnancy rate of 20%-27% per cycle."4.83A new era in ovulation induction. ( Casper, R; Holzer, H; Tulandi, T, 2006)
"To evaluate whether extending letrozole (LE) treatment duration could induce ovulation in women with polycystic ovary syndrome (PCOS) who previously failed to ovulate after a 5-day regimen of 5 mg LE daily for at least 1 ovulation induction cycle, defined as "LE resistance"."4.31Extending letrozole treatment duration is effective in inducing ovulation in women with polycystic ovary syndrome and letrozole resistance. ( Fu, Y; Zhu, X, 2023)
"To assess efficacy of adjuvant dexamethasone during letrozole cycles for ovulation induction (OI) in women with letrozole-resistant polycystic ovary syndrome (PCOS)."4.31Ovulation induction with letrozole and dexamethasone in infertile patients with letrozole-resistant polycystic ovary syndrome. ( Babayev, SN; Baumgarten, SC; Neblett, MF; Shenoy, CC, 2023)
" This study was performed to explore the relationship between follicle size, endometrial thickness, and types of ovarian stimulation (Clomiphene citrate/CC vs Letrozole) with biochemical pregnancy rate in women undergone IUI."4.31Association between follicle size, endometrial thickness, and types of ovarian stimulation (Clomiphene citrate and Letrozole) with biochemical pregnancy rate in women undergone intrauterine insemination. ( Krisnadi, SR; Nugrahani, AD; Rachmawati, A; Santoso, SA, 2023)
" Previous studies have shown that administration of letrozole, a non-steroidal aromatase inhibitor for cancer treatment, increased the clinical pregnancy rate in women with endometriosis, but the mechanisms remain to be determined."4.12Letrozole promotes the expression of integrin αvβ3 and HOXA10 in endometrium of endometriosis. ( Li, C; Li, M; Li, R; Wang, L; Zhang, H; Zhang, J, 2022)
"The risks of pregnancy, livebirth, multiple gestation, preterm birth, neonatal intensive care unit (NICU) admission and congenital malformations were higher for letrozole compared with clomiphene in participants with polycystic ovarian syndrome (PCOS), though no treatment differences were observed in those with unexplained infertility."4.12Emulating a target trial of the comparative effectiveness of clomiphene citrate and letrozole for ovulation induction. ( Chiu, YH; Hernán, MA; Hernández-Díaz, S; Hsu, J; Rinaudo, P; Yland, JJ, 2022)
"For infertile women with normal menstrual cycle undergoing FET, mildly stimulated cycles with letrozole present a relatively large advantage compared with HRT cycle and natural cycle, with higher live birth pregnancy, indicating that letrozole administration could improve pregnancy outcomes in this population."4.12Comparison of different endometrial preparation protocols on frozen embryo transfer pregnancy outcome in patients with normal ovulation. ( Bai, M; Chen, P; Lou, L; Lv, M; Xiao, Q; Xu, Y; Yu, J; Zhang, Z, 2022)
"To investigate the efficacy of oral letrozole (LE) starting on day 3 or 5 of the menstrual cycle in patients with polycystic ovary syndrome (PCOS)."4.12Effect of different timing of letrozole initiation on pregnancy outcome in polycystic ovary syndrome. ( Chen, Y; Gao, M; Jin, X; Shi, L; Ye, S; Zhang, Z, 2022)
"To evaluate the clinical effect of mild stimulation with letrozole on pregnancy outcomes in ovulatory women undergoing frozen embryo transfer (FET) compared to natural cycle."4.02Frozen Embryo Transfer in Mildly Stimulated Cycle With Letrozole Compared to Natural Cycle in Ovulatory Women: A Large Retrospective Study. ( Cai, R; Chen, Q; Huang, J; Khor, S; Kuang, Y; Li, D; Lu, X; Lyu, Q, 2021)
"We sought to compare the efficacy of the letrozole (LTZ) stair-step protocol with clomiphene citrate (CC) stair-step protocol in the management of 150 mg dose of CC-resistant polycystic ovary syndrome (PCOS) patients."4.02Comparison of the efficacy of letrozole stair-step protocol with clomiphene citrate stair-step protocol in the management of clomiphene citrate-resistant polycystic ovary syndrome patients. ( Oğlak, SC; Sakar, MN, 2021)
"The aim of this study was to compare a combination treatment with CC plus letrozole versus gonadotropins in CC-resistant polycystic ovary syndrome (PCOS) patients with regard to ovulation and clinical pregnancy rate."3.96A comparison between a combination of letrozole and clomiphene citrate versus gonadotropins for ovulation induction in infertile patients with clomiphene citrateresistant polycystic ovary syndrome - a retrospective study. ( Bademkıran, MH; Ege, S; Hançer Çaça, FN; Özçelik, SM; Peker, N; Tahaoğlu, AE, 2020)
"Children of women with polycystic ovary syndrome who conceived with letrozole (LTZ) or clomiphene (CC) in the PPCOS II study or women with unexplained infertility (AMIGOS study) who conceived with LTZ, CC, or gonadotropin (GN)."3.96Pregnancy registry: three-year follow-up of children conceived from letrozole, clomiphene, or gonadotropins. ( Alvero, R; Baker, V; Barnhart, KT; Casson, P; Cedars, MI; Christman, GM; Coutifaris, C; Coward, RM; Diamond, MP; Dodson, WC; Eisenberg, E; Estes, SJ; Hansen, KR; Huang, H; Krawetz, SA; Kunselman, A; Legro, RS; Robinson, R; Rosen, RM; Santoro, N; Schlaff, WD; Stetter, C; Trussell, JC; Usadi, R; Zhang, H, 2020)
" This article reports a case of successful ovulation induction and pregnancy with letrozole combined with HMG."3.96Successful live birth in a woman with resistant ovary syndrome treated with letrozole and HMG: A case report. ( Mu, Z; Song, J; Sun, Z; Yu, Y, 2020)
"To investigate whether live birth rate (LBR) following frozen-thawed embryo transfer in letrozole-stimulated cycles (L-FET) differs from LBR after artificial-cycle frozen-thawed embryos transfers (AC-FET) in women with polycystic ovary syndrome (PCOS)."3.91Letrozole use during frozen embryo transfer cycles in women with polycystic ovary syndrome. ( Chen, Q; Fan, Y; Kuang, Y; Liu, H; Mao, X; Wang, Y; Xiao, Y; Zhang, J, 2019)
" Clinical pregnancy rates were higher among women who received GnRH agonist plus letrozole compared with women who received GnRH agonist only or women without pretreatment (63%, 42%, and 40%, respectively; P<."3.91Effect of GnRH agonist and letrozole treatment in women with recurrent implantation failure. ( Balayla, J; Dahan, MH; Dahan, SY; Shrem, G; Steiner, N; Tan, SL; Tannus, S; Volodarsky-Perel, A, 2019)
"In an IUI program for unexplained or mild male-factor infertility, ovarian stimulation with letrozole may significantly increase live birth rates while controlling multiple pregnancy rates."3.88Ovarian stimulation in infertile women treated with the use of intrauterine insemination: a cohort study from China. ( Huang, S; Li, R; Mol, BWJ; Qiao, J; Wang, H; Wang, R, 2018)
"We compared sonographic findings, fertility results, pregnancy complications and congenital anomalies in two groups of women treated with letrozole and CC."3.88Comparison of the pregnancy outcomes and the incidence of fetal congenital abnormalities in infertile women treated with letrozole and clomiphene citrate. ( Akbari Sene, A; Ashrafi, M; Ghorbani, S, 2018)
"BACKGROUND Women with polycystic ovary syndrome (PCOS) undergoing in vitro fertilization (IVF) are given letrozole before a trigger injection of human chorionic gonadotropin (hCG) to lower estrogen (E2) levels, but can experience ovarian hyperstimulation syndrome (OHSS)."3.88A Retrospective Study of Letrozole Treatment Prior to Human Chorionic Gonadotropin in Women with Polycystic Ovary Syndrome Undergoing In Vitro Fertilization at Risk of Ovarian Hyperstimulation Syndrome. ( Chen, Y; Hao, C; Yang, T; Zhao, J, 2018)
"We conducted a secondary analysis of a multicenter, randomized clinical trial (Pregnancy in Polycystic Ovary Syndrome II, NCT00719186) comparing clomiphene citrate vs letrozole in the treatment of infertility."3.88Association among depression, symptom experience, and quality of life in polycystic ovary syndrome. ( Cedars, MI; Greenwood, EA; Huddleston, HG; Legro, RS; Pasch, LA, 2018)
"This retrospective study investigated the efficacy and safety of letrozole for patients with polycystic ovary syndrome (PCOS)."3.88Letrozole for patients with polycystic ovary syndrome: A retrospective study. ( Guang, HJ; Li, F; Shi, J, 2018)
"To assess the effect of letrozole in combination with low dose gonadotropins for ovulation induction in anovulatory infertility from polycystic ovary syndrome (PCOS) and controlled ovarian stimulation for endometriosis, and unexplained infertility patients."3.85Ovulation induction and controlled ovarian stimulation using letrozole gonadotropin combination: A single center retrospective cohort study. ( Arya, S; Crisp, Z; Dwivedi, AK; Jose, J; Kupesic-Plavsic, S; Mulla, ZD; Noble, LS, 2017)
"Variable dose letrozole-FSH protocol can maintain lower peak estradiol levels and reduce estrogen exposure after breast cancer operation and chemotherapy."3.83Twin delivery after IVF-ET with variable dose letrozole-FSH protocol of lower estradiol in a patient previously treated for breast cancer: a case report. ( Diao, H; Hu, GZ; Zhang, CJ; Zhang, Y, 2016)
"We have previously reported an approach to ovarian stimulation for the purpose of fertility preservation (FP) in women with breast cancer via embryo freezing with the concurrent use of letrozole."3.81Fertility Preservation Success Subsequent to Concurrent Aromatase Inhibitor Treatment and Ovarian Stimulation in Women With Breast Cancer. ( Bedoschi, G; Moy, F; Oktay, K; Pacheco, FS; Turan, V, 2015)
"To investigate the safety and feasibility of performing two consecutive ovarian stimulation cycles with the use of letrozole protocol for fertility preservation in breast cancer patients."3.79Safety and feasibility of performing two consecutive ovarian stimulation cycles with the use of letrozole-gonadotropin protocol for fertility preservation in breast cancer patients. ( Bedoschi, G; Moy, F; Oktay, K; Turan, V, 2013)
"To compare occurrence of pregnancy among obese (body mass index [BMI] ≥30) and nonobese (BMI <30), infertile women undergoing ovulation induction with the aromatase inhibitor letrozole followed by intrauterine insemination (IUI)."3.77Body mass index-associated differences in response to ovulation induction with letrozole. ( Bates, GW; Chapman, VR; Cliver, SP; Cooper, JJ; McKnight, KK; Nodler, JL, 2011)
"To determine the effect of intravaginal micronized P on pregnancy rates in clomiphene citrate and letrozole ovulation induction cycles in women with polycystic ovary syndrome (PCOS)."3.76Luteal support with intravaginal progesterone increases clinical pregnancy rates in women with polycystic ovary syndrome using letrozole for ovulation induction. ( Aubuchon, M; Khabbaz, M; Montville, CP; Thomas, MA; Williams, DB, 2010)
"Pregnancy rates were comparable between the letrozole-FSH co-treatment group and the FSH alone group."3.75Letrozole co-treatment in infertile women 40 years old and older receiving controlled ovarian stimulation and intrauterine insemination. ( Bedaiwy, MA; Casper, R; Claessens, A; Esfandiari, N; Gotleib, L; Mousa, N; Shokry, M, 2009)
"To investigate the effect of two different doses of letrozole in promoting ovulation in infertile women with polycystic ovarian syndrome (PCOS)."3.74[Effect of two different doses of letrozole in promoting ovulation in infertile women with polycystic ovarian syndrome]. ( Li, H; Quan, S; Song, YL; Xing, FQ; Yang, MQ, 2008)
"Letrozole induction of ovulation in clomiphene citrate-resistant women with polycystic ovary syndrome is associated with an ovulation rate of 54."3.73Letrozole induction of ovulation in women with clomiphene citrate-resistant polycystic ovary syndrome may not depend on the period of infertility, the body mass index, or the luteinizing hormone/follicle-stimulating hormone ratio. ( Eldosoky, M; Elnashar, A; Fouad, H; Saeid, N, 2006)
"Insulin resistance has a strong and independent association with depression in PCOS and may serve as a physiologic mediator."2.87Insulin resistance is associated with depression risk in polycystic ovary syndrome. ( Cedars, MI; Eisenberg, E; Greenwood, EA; Huddleston, HG; Legro, RS; Pasch, LA, 2018)
"Letrozole is a powerful endocrine medication that targets and inhibits the aromatase, often known as an aromatase inhibitor (AI)."2.82Letrozole: Pharmacology, toxicity and potential therapeutic effects. ( Chakraborty, R; Dey, A; Gopalakrishnan, AV; K K, V; Mukherjee, AG; Nagarajan, D; P, JP; Renu, K; T, TP; V, A; Vellingiri, B; Wanjari, UR, 2022)
"Letrozole, with lower incidences of LUF, is more effective than clomiphene citrate for the induction of ovulation in IUI cycles."2.80Effects of Letrozole-HMG and Clomiphene-HMG on Incidence of Luteinized Unruptured Follicle Syndrome in Infertile Women Undergoing Induction Ovulation and Intrauterine Insemination: A Randomised Trial. ( Akbari Asbagh, F; Azmoodeh, A; Ghaseminejad, A; Hamzehgardeshi, Z; Pejman Manesh, M, 2015)
" The aim of the study was to evaluate the effectiveness and efficacy of letrozole and clomiphene citrate (CC) combined with human menopausal gonadotropin (HMG) in CC-resistant infertile women with PCOS."2.80Use of letrozole and clomiphene citrate combined with gonadotropins in clomiphene-resistant infertile women with polycystic ovary syndrome: a prospective study. ( Liu, S; Lu, X; Mao, H; Xi, W; Xue, X; Yang, Y, 2015)
"letrozole for 5 treatment cycles (or approximately up to 25 weeks)."2.77The Pregnancy in Polycystic Ovary Syndrome II (PPCOS II) trial: rationale and design of a double-blind randomized trial of clomiphene citrate and letrozole for the treatment of infertility in women with polycystic ovary syndrome. ( Brzyski, RG; Casson, PR; Christman, GM; Coutifaris, C; Diamond, MP; Eisenberg, E; Kunselman, AR; Legro, RS; Santoro, N; Schlaff, WD; Taylor, HS; Zhang, H, 2012)
"Polycystic ovary syndrome is a common disease that is closely related to ovulation dysfunction and 7% of women of childbearing age are afflicted with it."2.77Comparison of the effects of letrozole and clomiphene citrate for ovulation induction in infertile women with polycystic ovary syndrome. ( Nahid, L; Sirous, K, 2012)
"The occurrence of pregnancy, miscarriage and neonatal condition."2.74Pregnancy outcome after ovulation induction with aromatase inhibitors or clomiphene citrate in unexplained infertility. ( Abdelhady, H; Allam, AF; Badawy, A; Shokeir, T, 2009)
" In Group A, an aromatase inhibitor (letrozole, 5 mg/day) was administered along with a fixed dosage (450 IU/day) of recombinant FSH (rFSH), whereas Group B were treated with the same rFSH dosage alone."2.74Use of aromatase inhibitors in poor-responder patients receiving GnRH antagonist protocols. ( Atabekoglu, CS; Olmus, H; Ozmen, B; Sönmezer, M, 2009)
" A total of 179 patients were randomly recruited in this prospective study with 58, 61 and 60 patients in each dosage group respectively."2.73Randomized controlled trial of three doses of letrozole for ovulation induction in patients with unexplained infertility. ( Badawy, A; Fawzy, M; Metwally, M, 2007)
"Letrozole was administered at 5 mg/day from day 3 to day 7 of the IUI cycle."2.72Letrozole versus human menopausal gonadotrophin in women undergoing intrauterine insemination. ( Attar, E; Baysoy, A; Jamal, H; Karatekeli, E; Ozornek, H; Serdaroglu, H, 2006)
"For patients with POR, controlled ovarian stimulation protocols using adjuvant treatment with DHEA, CoQ10 and GH showed better clinical outcomes in terms of achieving pregnancy, and a lower dosage of gonadotrophin required for ovulation induction."2.66Adjuvant treatment strategies in ovarian stimulation for poor responders undergoing IVF: a systematic review and network meta-analysis. ( Chang, HM; Guo, J; Huang, H; Leung, PCK; Sheng, JZ; Shu, J; Zhang, C; Zhang, Y, 2020)
"Letrozole has no beneficial effect on the prevention of mild, moderate, and severe OHSS, individually; Letrozole should not be considered as the first-line treatment for prevention of OHSS."2.66Whether Letrozole could reduce the incidence of early ovary hyperstimulation syndrome after assisted reproductive technology? A systematic review and meta-analysis. ( Huang, X; Li, Y; Xu, B; Yan, Y; Zhao, J, 2020)
"Obesity is also a feature of this syndrome and contributes to associated metabolic abnormalities."2.48Polycystic ovarian syndrome management options. ( Bates, GW; Propst, AM, 2012)
"Polycystic ovarian syndrome is the major cause of anovulation and is generally associated with obesity."2.48Evaluation and treatment of anovulatory and unexplained infertility. ( Bates, GW; Propst, AM, 2012)
"Breast cancer is the most frequent cancer in reproductive age women."2.44Assisted reproduction and breast cancer. ( Atabekoglu, C; Sonmezer, M, 2007)
"Letrozole co-treatment significantly suppressed oestradiol and follicle-stimulating hormone concentrations from stimulation day 5 and onwards, while increasing luteinizing hormone levels on stimulation day 5 and trigger day."1.91Impact of 2.5 mg versus 5 mg letrozole co-treatment in an antagonist protocol for IVF: a retrospective study. ( Lin, J; Wang, B; Wu, F; Zhang, K; Zhu, Q; Zhu, Y, 2023)
" This study aimed to investigate the effect of letrozole and metformin combined with targeted nursing on ovarian function, LH, and FSH in infertile patients with PCOS."1.72The Effects of Letrozole and Metformin Combined with Targeted Nursing Care on Ovarian Function, LH, and FSH in Infertile Patients with Polycystic Ovary Syndrome. ( Jiang, S; Li, R; Sheng, Y; Tang, T; Xu, H, 2022)
"To ask lots of questions and try to find the truth about the medicine-based effectiveness of letrozole (LE) combined with human menopausal gonadotropin (HMG) in the treatment of inability to have children crops patients with endocrine (things that are different from what is usually expected and the effect on ovulation-related chemicals produced by the body)."1.72Efficacy of Letrozole Combined with Urinary Gonadotropin for Ovulation Induction in Endocrine Abnormal Infertility Patients: A Retrospective Single-Center, Case-Control Study. ( Luo, S; Mao, J; Peng, H; Wang, J; Yuan, B, 2022)
"Retrospective cohort study of 118 breast cancer patients undergoing fertility preservation treatment between 2008 and 2018."1.62Effects of letrozole or tamoxifen coadministered with a standard stimulation protocol on fertility preservation among breast cancer patients. ( Almog, B; Azem, F; Cohen, Y; Fouks, Y; Kalma, Y; Shulman, Y, 2021)
"Letrozole was associated with significantly higher clinical pregnancy (38."1.62Letrozole as first-line drug for ovulation induction in treatment-naïve infertile polycystic ovarian syndrome women. ( Joseph, T; Kamath, MS; Kunjummen, AT; Rebekah, G; Waanbah, BD, 2021)
"Letrozole is a risk factor for worse oocyte morphology."1.56The impact of letrozole administration on oocyte morphology in breast cancer patients undergoing fertility preservation. ( Alves, VR; Bercaire, LMN; Cavagna, F; Cavagna, M; Donadio, NF; Dzik, A; Gebrim, LH; Nahas, EAP; Portela, R; Rocha, AR; Santos, TBB, 2020)
"Letrozole-treated patients required a significantly lower amount of gonadotropins units (p < 0."1.48Mild ovarian stimulation with letrozole plus fixed dose human menopausal gonadotropin prior to IVF/ICSI for infertile non-obese women with polycystic ovarian syndrome being pre-treated with metformin: a pilot study. ( Cantatore, C; Caringella, AM; Caroppo, E; D'Amato, G; Palini, S; Stanziano, A, 2018)
"Polycystic ovary syndrome is the most common endocrinopathy among reproductive-aged women in the United States, affecting approximately 7% of female patients."1.43Diagnosis and Treatment of Polycystic Ovary Syndrome. ( Mortada, R; Porter, S; Williams, T, 2016)
"To evaluate the efficacy of minimal stimulation using discretely administered gonadotropin combined with clomiphene citrate (CC) or letrozole (LTZ) for intrauterine insemination (IUI) cycles."1.42Minimal stimulation using gonadotropin combined with clomiphene citrate or letrozole for intrauterine insemination. ( Cho, S; Choi, YS; Chon, SJ; Kim, SH; Lee, BS; Park, JH; Seo, SK; Yun, BH, 2015)
"Treatment with letrozole resulted in a smaller rise in the follicular phase FSH, which was shorter in duration than with CC."1.42A comparison of endometrial thickness following augmentation of ovulation with clomifene citrate or letrozole in women with ovulatory infertility. ( Palihawadana, TS; Seneviratne, HR; Wijesinghe, PS, 2015)
" Demographic and endocrine characteristics, the total number of oocytes retrieved, cancellation rate and clinical pregnancy rate were collected Results: Total dosage of gonadotropins (p=0."1.40The comparision of effect of microdose GnRH-a flare-up, GnRH antagonist/aromatase inhibitor letrozole and GnRH antagonist/clomiphene citrate protocols on IVF outcomes in poor responder patients. ( Bakacak, M; Ficicioglu, C; Kaspar, C; Kizilkale, O; Ozcan Cenksoy, P; Suhha Bostanci, M; Yesiladali, M, 2014)
"Three patients with a diagnosis of breast cancer requiring emergency fertility preservation in the late follicular or luteal phase of the menstrual cycle."1.37Random-start controlled ovarian hyperstimulation for emergency fertility preservation in letrozole cycles. ( Coşkun, U; Oktay, K; Sönmezer, M; Türkçüoğlu, I, 2011)
"Letrozole is a potent, nonsteroidal, aromatase inhibitor, originally used for postmenopausal breast cancer therapy, at present its only registered indication."1.37Use of the aromatase inhibitor letrozole for ovulation induction in women with polycystic ovarian syndrome. ( Casper, RF; Mitwally, MF, 2011)
"Forty-year-old woman with breast cancer seeking fertility preservation before chemotherapy."1.35In vitro maturation of germinal vesicle oocytes recovered after premature luteinizing hormone surge: description of a novel approach to fertility preservation. ( Chian, RC; Demirtas, E; Lostritto, K; Oktay, K; Son, WY; Tan, SL, 2008)
"Letrozole is an effective drug for ovulation induction and superovulation."1.34Limiting access to letrozole--is it justified? ( DeCherney, AH; Tulandi, T, 2007)
"Letrozole was administered per os daily in a dose of 1 mg/kg b."1.34[The role of the ovarian steroid aromatase in pathogenesis of reproductive cycles disorders]. ( Reznikov, OH; Tarasenko, LV, 2007)

Research

Studies (207)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's39 (18.84)29.6817
2010's111 (53.62)24.3611
2020's57 (27.54)2.80

Authors

AuthorsStudies
Li, D1
Khor, S1
Huang, J1
Chen, Q2
Lyu, Q1
Cai, R1
Kuang, Y3
Lu, X2
Asgharnia, M1
Mehrafza, M1
Raoufi, A1
Zare Yousefi, T1
Hosseinzadeh, E1
Samadnia, S1
Zahiri, Z1
Tamimi, A1
Hosseini, A1
Zhang, J2
Wang, L1
Li, C1
Zhang, H8
Li, R5
Li, M1
Yland, JJ1
Chiu, YH1
Rinaudo, P1
Hsu, J1
Hernán, MA1
Hernández-Díaz, S1
Guo, W1
Li, HWR1
Yang, Z1
Zeng, L1
Yang, R1
Qiao, J4
Ng, EHY2
Jiang, S1
Tang, T1
Sheng, Y2
Xu, H1
Silveira, CO1
Oliveira, RM1
Moraes, LM1
Oliveira, GG1
Aguiar, LPT1
Souza, FHS1
Coelho, SS1
Prazeres, PHDM1
Del Puerto, HL1
Ferreira, MCF1
Wessel, JA1
Danhof, NA1
van Eekelen, R1
Diamond, MP6
Legro, RS16
Peeraer, K1
D'Hooghe, TM1
Erdem, M1
Dankert, T1
Cohlen, BJ1
Thyagaraju, C1
Mol, BWJ3
Showell, M1
van Wely, M3
Mochtar, MH1
Wang, R5
Aramesh, S1
Azizi Kutenaee, M1
Najafi, F1
Ghaffari, P1
Taghavi, SA2
Peng, H1
Yuan, B1
Mao, J1
Wang, J1
Luo, S1
Lou, L1
Xu, Y1
Lv, M1
Yu, J1
Xiao, Q1
Chen, P1
Bai, M1
Zhang, Z3
Panda, SR1
Sharmila, V1
Kalidoss, VK1
Hota, S1
Franik, S3
Le, QK1
Kremer, JA3
Kiesel, L2
Farquhar, C3
Mukherjee, AG1
Wanjari, UR1
Nagarajan, D1
K K, V1
V, A1
P, JP1
T, TP1
Chakraborty, R1
Renu, K1
Dey, A1
Vellingiri, B1
Gopalakrishnan, AV1
Zhu, X1
Fu, Y1
Shi, L3
Ye, S2
Gao, M2
Chen, Y4
Jin, X2
Hossein Rashidi, B1
Shahrokh Tehraninejad, E1
Amanpour, S1
Bandarian, F1
Bandarian, M1
Dai, X1
Li, J4
Fu, T1
Long, X1
Li, X1
Weng, R1
Liu, Y2
Zhang, L1
Liu, Z1
Geng, Y1
Huang, Y1
Hu, R2
Li, F2
Song, Y1
Zhang, M1
Akgul, OK1
Guraslan, H1
Panchal, D1
Pandya, T1
Kevlani, V1
Shah, S1
Acharya, S1
Lin, J3
Shen, X1
Zhu, Q2
Akintoye, OO1
Ajibare, AJ1
Oriyomi, IA1
Olofinbiyi, BA1
Yusuf, GO1
Afuye, DC1
Babalola, TK1
Faturoti, OE1
Oludipe, S1
Owoyele, VB1
Neblett, MF1
Baumgarten, SC1
Babayev, SN1
Shenoy, CC1
Xia, TT1
Zeng, KF1
Peng, QM1
Al-Thuwaynee, S1
Swadi, AAJ1
Rachmawati, A1
Krisnadi, SR1
Santoso, SA1
Nugrahani, AD1
Chera-Aree, P1
Tanpong, S1
Thanaboonyawat, I1
Laokirkkiat, P1
Wu, F1
Zhang, K1
Zhu, Y1
Wang, B1
Tshzmachyan, R1
Hambartsoumian, E1
Kaur, J1
Suri, V1
Gainder, S1
Arora, A1
Li, W1
Bordewijk, EM1
Wu, X1
Gao, J1
Morin-Papunen, L1
Homburg, R1
König, TE1
Moll, E1
Kar, S1
Huang, W3
Johnson, NP2
Amer, SA2
Vegetti, W1
Palomba, S1
Falbo, A1
Özmen, Ü1
Nazik, H1
Williams, CD1
Federica, G1
Lord, J1
Sahin, Y1
Bhattacharya, S2
Norman, RJ4
Mol, BW2
Shi, S1
Hong, T1
Jiang, F1
Zhuang, Y1
Chen, L1
Huang, X2
Zhang, Y3
Zhang, C2
Shu, J1
Guo, J1
Chang, HM1
Leung, PCK1
Sheng, JZ1
Huang, H5
Najafi, PZ1
Noghabi, SP1
Afzali, N1
Mohammadzadeh, S1
Huang, S3
Hu, M1
Stener-Victorin, E3
Zheng, Y1
Wen, Q1
Wang, C1
Lai, M2
Gao, X1
Wang, X1
Hu, Z2
Xia, T1
Liu, J1
Wen, X1
Li, S2
Quan, K1
Liang, X1
Shang, H1
Ma, H2
Ege, S1
Bademkıran, MH1
Peker, N1
Tahaoğlu, AE1
Hançer Çaça, FN1
Özçelik, SM1
Bercaire, LMN1
Cavagna, M1
Donadio, NF1
Rocha, AR1
Portela, R1
Alves, VR1
Santos, TBB1
Cavagna, F1
Dzik, A1
Gebrim, LH1
Nahas, EAP1
Coutifaris, C5
Schlaff, WD3
Alvero, R4
Casson, P4
Christman, GM5
Rosen, RM3
Cedars, MI4
Hansen, KR3
Robinson, R1
Baker, V4
Usadi, R4
Dodson, WC1
Estes, SJ1
Kunselman, A1
Stetter, C1
Barnhart, KT2
Coward, RM1
Trussell, JC4
Krawetz, SA4
Santoro, N5
Eisenberg, E6
Mu, Z1
Song, J1
Yu, Y1
Sun, Z1
Rose, BI1
Brown, SE1
Qin, F1
Zhou, Y1
Huan, L1
Gui, W1
Mvondo, MA1
Mzemdem Tsoplfack, FI1
Awounfack, CF1
Njamen, D1
Bansal, S1
Goyal, M1
Sharma, C1
Shekhar, S1
Atwa, KA1
Farrag, MM1
El-Sayed, MM1
Taha, OT1
Elprince, M1
Zhao, J2
Xu, B1
Yan, Y1
Li, Y2
Pundir, J1
Achilli, C1
Bhide, P1
Sabatini, L1
Rombauts, L2
Teede, H2
Coomarasamy, A1
Zamora, J1
Thangaratinam, S1
Amrane, S1
Vitez, SF1
Palmerola, KL1
Lobo, RA1
Shulman, Y1
Almog, B1
Kalma, Y1
Fouks, Y1
Azem, F1
Cohen, Y1
Zeng, MF1
Zhou, X1
Duan, JL1
Zhou, L2
Fu, J2
Liu, D2
Wang, Q2
Chen, H1
Yang, S2
Tsiami, AP1
Goulis, DG1
Sotiriadis, AI1
Kolibianakis, EM1
Zhang, X1
Zheng, A1
Yang, J2
Feng, T1
Hao, Y1
Qian, Y1
Hansda, SR1
Haldar, C1
Yang, AM1
Cui, N1
Sun, YF1
Hao, GM1
Sakar, MN1
Oğlak, SC1
Letourneau, J1
Juarez-Hernandez, F1
Wald, K1
Ribeiro, S1
Wang, A1
McCulloch, CE1
Mok-Lin, E1
Dolezal, M1
Chien, AJ1
Rosen, M1
Collée, J1
Mawet, M1
Tebache, L1
Nisolle, M1
Brichant, G1
Waanbah, BD1
Joseph, T1
Rebekah, G1
Kunjummen, AT1
Kamath, MS3
Tatsumi, T1
Jwa, SC1
Kuwahara, A1
Irahara, M1
Kubota, T1
Saito, H1
Liu, C1
Feng, G1
Tan, J1
Zhang, D1
Smith, J1
Mahran, A1
Fox, P1
Fakis, A1
Siristatidis, C1
Haas, J2
Casper, RF9
Arya, S1
Kupesic-Plavsic, S1
Mulla, ZD1
Dwivedi, AK1
Crisp, Z1
Jose, J1
Noble, LS1
Farquhar, CM1
Liu, E1
Armstrong, S1
Arroll, N1
Lensen, S1
Brown, J1
Hu, S2
Yu, Q2
Wang, Y3
Wang, M1
Xia, W2
Zhu, C2
Wang, H2
Eltrop, SM1
Bassil, R1
Gonen, N1
Meriano, J1
Jurisicova, A1
Greenwood, EA2
Pasch, LA2
Huddleston, HG2
Akbari Sene, A1
Ghorbani, S1
Ashrafi, M1
Yang, T1
Hao, C1
D'Amato, G1
Caringella, AM1
Stanziano, A1
Cantatore, C1
Palini, S1
Caroppo, E1
Rezk, M1
Hamza, H1
El-Shamy, ES1
Yun, J1
Choi, YS3
Lee, I1
Won, YB1
Lee, JH1
Seo, SK3
Cho, S3
Lee, BS3
Yun, BH2
Du, X1
Luo, L1
O'Leary, S1
Guang, HJ1
Shi, J1
Rodriguez-Purata, J1
Lee, J1
Whitehouse, M1
Sandler, B1
Copperman, A1
Mukherjee, T1
Cutler, DA1
Shaw, AK1
Pride, SM1
Bedaiwy, MA3
Cheung, AP1
Teede, HJ1
Misso, ML1
Boyle, JA1
Garad, RM1
McAllister, V1
Downes, L1
Gibson, M1
Hart, RJ1
Moran, L1
Dokras, A1
Laven, J1
Piltonen, T1
Rodgers, RJ1
Thondan, M1
Costello, MF2
Quaas, AM1
Goldrat, O2
Van Den Steen, G1
Gonzalez-Merino, E1
Dechène, J1
Gervy, C2
Delbaere, A2
Devreker, F1
De Maertelaer, V1
Demeestere, I2
Mejia, RB1
Summers, KM1
Kresowik, JD1
Van Voorhis, BJ1
Shao, YH1
Tulandi, T7
Cheng, G1
Eskew, AM1
Bedrick, BS1
Hardi, A1
Stoll, CRT1
Colditz, GA1
Tuuli, MG1
Jungheim, ES1
Pourghasem, S1
Bazarganipour, F1
Kutenaee, MA1
Al-Obaidi, MT1
Ali, ZH1
Al-Saadi, WI1
Al-Wasiti, EAR1
Al-Aubaidy, H1
Liu, H1
Mao, X1
Fan, Y1
Xiao, Y1
Steiner, N1
Shrem, G1
Tannus, S2
Dahan, SY1
Balayla, J1
Volodarsky-Perel, A1
Tan, SL3
Dahan, MH3
Ozdemir, U1
Ozaksit, G1
Cakir Gungor, AN1
Aydogan, M1
Jeon, YE1
Jung, JA1
Kim, HY1
Turan, V2
Bedoschi, G2
Moy, F2
Oktay, K5
Malloch, L1
Rhoton-Vlasak, A1
Ganesh, A2
Chauhan, N1
Das, S1
Chakravarty, B1
Chaudhury, K2
Wang, YQ1
Xu, WM1
Xie, QZ1
Yan, WJ1
Yin, TL1
Cheng, D1
Xiao, ZN1
Hajishafiha, M1
Dehghan, M1
Kiarang, N1
Sadegh-Asadi, N1
Shayegh, SN1
Ghasemi-Rad, M1
Antonson, P1
Matic, M1
Portwood, N1
Kuiper, RV1
Bryzgalova, G1
Gao, H1
Windahl, SH1
Humire, P1
Ohlsson, C1
Berggren, PO1
Gustafsson, JÅ1
Dahlman-Wright, K1
Nelen, WL1
Ozcan Cenksoy, P1
Ficicioglu, C1
Kizilkale, O1
Suhha Bostanci, M1
Bakacak, M1
Yesiladali, M1
Kaspar, C1
Liu, A1
Zheng, C1
Lang, J1
Chen, W1
Chaudhury, S1
Khastgir, G1
Purakaystha, S1
Brzyski, RG2
Yan, Q1
Haisenleder, DJ1
Bates, GW6
Lucidi, S1
Snyder, P1
Ohl, D2
Fauser, BC2
Zhao, Y1
Du, B1
Jiang, X1
Ma, M1
Zhang, Q1
Sharma, S2
Ghosh, S1
Singh, S1
Chakravarty, A1
Rajani, S1
Chakravarty, BN1
Warraich, G1
Vause, TD1
He, Q1
Xu, J1
Cui, S1
Li, H2
Ecklund, LC1
Usadi, RS2
Chon, SJ1
Park, JH1
Kim, SH2
Robinson, RD2
Ager, J2
Seungdamrong, A2
Haisonleder, D1
Barnhart, K2
Jin, Y2
Klement, AH1
Kim, JH1
Kim, SK1
Lee, HJ1
Lee, JR1
Jee, BC1
Suh, CS1
Spritzer, PM1
Motta, AB1
Sir-Petermann, T1
Diamanti-Kandarakis, E1
Cakmak, H1
Rosen, MP1
Pacheco, FS1
Englert, Y1
Palihawadana, TS1
Wijesinghe, PS1
Seneviratne, HR1
Haisenleder, D1
Roque, M1
Tostes, AC1
Valle, M1
Sampaio, M1
Geber, S1
Sharief, M1
Nafee, NR1
Azmoodeh, A1
Pejman Manesh, M1
Akbari Asbagh, F1
Ghaseminejad, A1
Hamzehgardeshi, Z1
El-khayat, W1
Abdel Moety, G1
Al Mohammady, M1
Hamed, D1
Burke, YZ1
Kol, S1
Xi, W1
Liu, S1
Mao, H1
Yang, Y1
Xue, X1
Saha, J1
Akhter, S1
Prasad, I1
Siddiq, S1
Leung, AS1
Birch Petersen, K1
Pedersen, NG1
Pedersen, AT1
Lauritsen, MP1
la Cour Freiesleben, N1
Zhang, CJ1
Hu, GZ1
Diao, H1
Bastu, E1
Buyru, F1
Ozsurmeli, M1
Demiral, I1
Dogan, M1
Yeh, J1
Wu, XK1
Wang, YY1
Liu, JP1
Liang, RN1
Xue, HY1
Ma, HX1
Shao, XG1
Ng, EH3
Williams, T1
Mortada, R1
Porter, S1
Balen, AH1
Morley, LC1
Misso, M1
Franks, S1
Wijeyaratne, CN1
Domingo, J1
Garcia-Velasco, JA1
Wu, W1
Wu, T1
Kim, BV1
Olgan, S1
Humaidan, P1
Partridge, AH1
Badawy, A5
Elnashar, A2
Totongy, M1
Yang, MQ1
Quan, S1
Song, YL1
Xing, FQ1
Chen, ZJ1
Shi, YH1
Gao, Q1
Ma, ZX1
Shokeir, T2
Allam, AF1
Abdelhady, H1
Samani, FG1
Farzadi, L1
Nezami, N1
Tarzamni, MK1
Soleimani, F1
Montville, CP1
Khabbaz, M1
Aubuchon, M1
Williams, DB1
Thomas, MA1
Abu Hashim, H2
Polyzos, NP1
Tzioras, S1
Badawy, AM1
Valachis, A1
Dritsas, C1
Mauri, D1
Ozmen, B1
Sönmezer, M3
Atabekoglu, CS1
Olmus, H1
Aleyamma, TK1
Chandy, A1
George, K2
Alborzi, S2
Hamedi, B1
Omidvar, A1
Dehbashi, S1
Alborzi, M1
Rodriguez-Wallberg, KA1
Türkçüoğlu, I1
Coşkun, U1
Abdellah, MS1
Fouda, UM1
Sayed, AM1
McKnight, KK1
Nodler, JL1
Cooper, JJ1
Chapman, VR1
Cliver, SP1
Banerjee Ray, P1
Ray, A1
Chakraborti, PS1
Mitwally, MF4
Wiser, A1
Shalom-Paz, E1
Reinblatt, SL1
Holzer, H2
El Rakhawy, M1
Abd Elaal, I1
Miller, PB1
Parnell, BA1
Bushnell, G1
Tallman, N1
Forstein, DA1
Higdon, HL1
Kitawaki, J1
Lessey, BA1
Kunselman, AR1
Casson, PR1
Taylor, HS1
Zadehmodares, S1
Niyakan, M1
Sharafy, SA1
Yazdi, MH1
Jahed, F1
Nahid, L1
Sirous, K1
Ibrahim, MI1
Moustafa, RA1
Abdel-Azeem, AA1
Khanna, SC1
Kumar, A1
Joy, SG1
Tanwar, R1
Prasad, S1
Mohsen, IA1
El Din, RE1
Propst, AM2
Abd Elgafor, I1
Mudur, G1
Sharma, DC1
Ahmad, K1
Al-Fozan, H1
Al-Khadouri, M1
Cortínez, A1
De Carvalho, I1
Vantman, D1
Gabler, F1
Iñiguez, G1
Vega, M1
Sohrabvand, F1
Ansari, Sh1
Bagheri, M1
Bayar, U1
Tanriverdi, HA1
Barut, A1
Ayoğlu, F1
Ozcan, O1
Kaya, E1
Casper, R2
Fouad, H1
Eldosoky, M1
Saeid, N1
Martin, J1
Al-Fadhli, R1
Kabli, N1
Forman, R2
Hitkari, J1
Librach, C1
Greenblatt, E1
Verpoest, WM1
Kolibianakis, E1
Papanikolaou, E1
Smitz, J1
Van Steirteghem, A1
Devroey, P1
Baysoy, A1
Serdaroglu, H1
Jamal, H1
Karatekeli, E1
Ozornek, H1
Attar, E1
Barroso, G1
Menocal, G1
Felix, H1
Rojas-Ruiz, JC1
Arslan, M1
Oehninger, S1
Begum, MR1
Quadir, E1
Begum, A1
Begum, RA1
Begum, M1
Mousa, NA1
Esfandiari, N2
DeCherney, AH1
Schoolcraft, WB1
Surrey, ES1
Minjarez, DA1
Stevens, JM1
Gardner, DK1
Kafy, S1
Tarasenko, LV1
Reznikov, OH1
Metwally, M1
Fawzy, M1
Demirtas, E1
Son, WY1
Lostritto, K1
Chian, RC1
Mosbah, A1
Shady, M1
Rowe, T1
Marasinghe, JP1
Chintana, HD1
Amarasinghe, AA1
Atabekoglu, C1
Quintero, RB1
Urban, R1
Belaisch, J1
Shokry, M1
Mousa, N1
Claessens, A1
Gotleib, L1

Clinical Trials (46)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized Trial of Letrozole as an Adjunct to Follicle Stimulating Hormone in Stimulated in Vitro Fertilization Cycles[NCT02912988]Phase 3900 participants (Actual)Interventional2018-03-01Completed
Administration of Single High Dose Letrozole for Ovulation Induction - A Randomized Controlled Trial[NCT02703649]Phase 436 participants (Actual)Interventional2016-03-31Completed
Laparoscopic Ovarian Drilling Versus Letrozole In Clomiphene Citrate Resistant Polycystic Ovary: A Randomized Controlled Trial[NCT03664050]Phase 390 participants (Anticipated)Interventional2018-01-01Recruiting
Efficacy of Combined Letrozole-metformin in Comparison With Letrozole Only in Clomiphene Resistant Infertile Women With Polycystic Ovarian Syndrome[NCT03135301]Phase 380 participants (Anticipated)Interventional2017-06-20Recruiting
Dosage Optimization for Letrozole Treatment in Clomiphene Resistant Patients With Polycystic Ovary Syndrome: A Prospective Interventional Study[NCT01315912]Phase 444 participants (Actual)Interventional2008-01-31Completed
A Multicenter Randomized Trial of Personalized Acupuncture, Fixed Acupuncture, Letrozole and Placebo on Live Birth for Infertility in Women With Polycystic Ovary Syndrome[NCT03625531]Phase 31,100 participants (Anticipated)Interventional2018-08-13Recruiting
Intrauterine Insemination With Letrozole Versus Intrauterine Insemination in Natural Cycle. A Randomised Controlled Trial[NCT03455426]100 participants (Actual)Interventional2018-03-15Completed
Letrozole Versus Laparoscopic Ovarian Drilling for Clomiphene-resistant Women With Polycystic Ovary Syndrome[NCT03009838]Phase 3150 participants (Anticipated)Interventional2017-01-02Recruiting
To Investigate the Effectiveness of Adjuvant Supplements Prior to in Vitro Fertilization Cycles[NCT05471453]90 participants (Anticipated)Interventional2022-03-02Recruiting
Effects of Autologous Intraovarian Platelet Rich Plasma in Women With Poor Ovarian Response[NCT04797377]66 participants (Actual)Interventional2021-03-16Completed
Fertility Preservation Using Tamoxifen and Letrozole in Estrogen Sensitive Tumors Trial[NCT03011684]Phase 3144 participants (Anticipated)Interventional2016-07-21Recruiting
Double Blind Cross-over Randomized Controlled Trial Comparing Letrozole Versus Clomifene Citrate for Ovulation Induction in Women With Polycystic Ovarian Syndrome[NCT00478504]Phase 4159 participants (Actual)Interventional2007-05-31Completed
Follicular Synchronization in Polycystic Ovarian Syndrome Patients Undergoing Intracytoplasmatic Sperm Injection With Letrozole /Antagonist Protocol: A Randomized Controlled Trial[NCT04069117]Phase 4200 participants (Actual)Interventional2019-08-01Completed
A 20 Week Double-Blind Randomized Trial of Clomiphene Citrate and Letrozole for the Treatment of Infertility in Women With Polycystic Ovary Syndrome[NCT00719186]Phase 3750 participants (Actual)Interventional2009-02-28Completed
Graceful Lifestyle Changes Intervention Study for Women With PCOS and Infertility[NCT02630485]240 participants (Anticipated)Interventional2015-12-31Not yet recruiting
Efficiency and Safety Study of Ovarian Stimulation With Letrozole for Fertility Preservation in Breast Cancer Patients[NCT02661932]Phase 465 participants (Actual)Interventional2012-11-30Active, not recruiting
Combined Letrozole and Clomid in Polycystic Ovary Syndrome: a Randomized Control Trial of Combination of Letrozole and Clomiphene Citrate or Letrozole Alone for the Treatment of Infertility in Women With Polycystic Ovary Syndrome[NCT02802865]Phase 470 participants (Actual)Interventional2016-08-31Completed
Hormonal Replacement Therapy Plus Letrozole Incorporation Versus Letrozole Mild Ovarian Stimulation in Endometrial Preparation for Frozen Embryo Transfer: A Randomised Controlled Trial[NCT06181305]Phase 4210 participants (Anticipated)Interventional2023-12-12Not yet recruiting
The Randomized Clinical Trials of Letrozole Administration During Luteal Phase in Patients Who Have the Risk of Ovarian Hyperstimulation Syndrome[NCT02686151]Phase 350 participants (Anticipated)Interventional2023-12-31Not yet recruiting
COmbining Oral Letrozole and Clomiphene for Ovarian Stimulation (COOL-COS) Associated With Corifollitropin Alfa: a Pilot Study[NCT02448459]Phase 140 participants (Actual)Interventional2015-05-31Completed
Evaluation of a Simplified Low-cost and Friendly Controlled Ovarian Stimulation Combining Oral Letrozole and Clomiphene Citrate: a Pilot Study[NCT02288143]Phase 428 participants (Actual)Interventional2015-01-31Completed
Letrozole and Sequential Clomiphene to Improve the Outcome of Embryo Transfer in Polycystic Ovary Syndrome (PCOS) Patients[NCT02775877]100 participants (Anticipated)Interventional2016-05-31Recruiting
Comparison of Tamoxifen and Clomiphene Citrate in Mild Stimulation IVF: a Prospective Cohort Study[NCT02690870]Phase 4210 participants (Anticipated)Interventional2017-01-31Not yet recruiting
Is the Co-administration of Metformine and CC as Compared to Placebo and CC Superior to Induce Ovulation in PCOS Patients With a Confirmed insulin-resistant-a Double Blind Randomized Clinical Trial[NCT02523898]Phase 2388 participants (Anticipated)Interventional2015-11-30Enrolling by invitation
Effect of Acupuncture Pre-treatment Combined With Letrozole on Live Birth in Infertile Women With Polycystic Ovary Syndrome[NCT02491320]Phase 3384 participants (Actual)Interventional2015-08-31Completed
Assessment of Multiple Intrauterine Gestations From Ovarian Stimulation[NCT01044862]Phase 3900 participants (Actual)Interventional2010-06-30Completed
Double Ovarian Stimulation in Cases of Preimplantation Genetic Testing: Comparison of Embryo Quantity and Embryonic Quality Using MitoScore[NCT03291821]136 participants (Actual)Interventional2017-12-01Completed
Safety of Ovarian Stimulation With Letrozole and Gonadotropins in Breast Cancer Patients Undergoing Embryo or Oocyte Cryopreservation: A Prospective Controlled Follow up Study[NCT00504699]120 participants (Actual)Interventional2002-01-31Terminated (stopped due to The PI left the Institution.)
Combined Letrozole-metformin-pioglitazone Versus Combined Clomiphene Citrate-metformin-pioglitazone in Clomiphene Citrate-resistant Women With Polycystic Ovary Syndrome[NCT01909141]Early Phase 1100 participants (Actual)Interventional2013-08-31Completed
Clinical Effect of Follicular Preparation With Testosterone in Poor Ovarian Response: a Randomized Controlled Clinical Trial (TESTOPRIM)[NCT03378713]Phase 363 participants (Actual)Interventional2017-08-07Completed
The Angiotensin-Melatonin Axis in Poor and Hyper Responders for IVF Treatment[NCT05298657]200 participants (Anticipated)Observational [Patient Registry]2022-09-01Not yet recruiting
Extended Letrozole Regimen Versus Clomiphene Citrate for Superovulation in Patients With Unexplained Infertility Undergoing Intrauterine Insemination[NCT01232075]Phase 2214 participants (Actual)Interventional2008-09-30Completed
"Supplementation of the Luteal Phase With Vaginal Progesterone (Crinone 8%) in Women With Polycystic Ovary Syndrome Undergoing Ovulation Induction With Letrozole: A Prospective and Randomized Controlled Trial"[NCT03440359]Phase 2/Phase 352 participants (Actual)Interventional2012-07-06Completed
Phase II Randomized Study of Neoadjuvant Metformin Plus Letrozole vs Placebo Plus Letrozole for ER-positive Postmenopausal Breast Cancer[NCT01589367]Phase 2208 participants (Actual)Interventional2012-05-31Completed
A Scientific & Clinical Review of Minimal Stimulation Protocol Using AROMEK (Letrozole) and Follitrope (Recombinant FSH)Combined With INVOCell(Intravaginal Culturing) - Effectiveness as Low Cost IVF[NCT01058252]30 participants (Anticipated)Observational2021-05-31Recruiting
Evolutive Potential of Embryos Obtained From Oocytes After Luteal Phase Ovarian Stimulation[NCT01645241]15 participants (Actual)Interventional2012-07-31Completed
Clomiphene Citrate Plus HPuFSH Versus Letrozole Plus HPuFSH in Clomid Resistant Infertile PCOS Women[NCT01793038]160 participants (Anticipated)Interventional2013-03-31Recruiting
Letrozole Plus Misoprostol Versus Misoprostol Alone in Induction of Abortion of Anembryonic Pregnancy:[NCT05198050]96 participants (Actual)Interventional2022-04-03Completed
Comparison Between the Role of Follicular Output Rate and Preovulatory Count in the Prediction of Pregnancy in Women With Polycystic Ovarian Syndrome Undergoing Intra Cytoplasmic Sperm Injection (ICSI)[NCT02190006]300 participants (Anticipated)Observational2014-07-31Recruiting
Letrozole and CC Alone in an IUI Program in Women With Surgically Treated Minimal to Mild Endometriosis[NCT01334762]136 participants (Actual)Interventional2007-05-31Completed
A Randomized Controlled Study to Compare the Outcome of Two Protocols Used to Prepare the Endometrium for Frozen Embryo Transfer[NCT04507022]Phase 4112 participants (Actual)Interventional2020-08-12Completed
The Role of Estrogen in Luteinizing Hormone Surge and Ovulation[NCT01999569]Phase 410 participants (Actual)Interventional2007-04-30Completed
Induction of Ovulation With Raloxifene or Clomiphene Citrate in Polycystic Ovarian Syndrome[NCT00427700]Phase 382 participants (Actual)Interventional2008-08-31Completed
Letrozole Versus Combined Metformin and Clomiphene Citrate for Ovulation Induction in Clomiphene-Resistant Women With Polycystic Ovary Syndrome[NCT00911313]250 participants (Actual)Interventional2006-06-30Completed
Letrozole Versus Laparoscopic Ovarian Diathermy for Ovulation Induction in Clomiphene-resistant Women With Polycystic Ovary Syndrome[NCT00956267]260 participants (Actual)Interventional2006-08-31Completed
Use of High Cost Monitoring During Letrozole Ovulation Induction and Effect on Pregnancy Rates - A Pilot Study[NCT01279200]Phase 421 participants (Actual)Interventional2011-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Live Birth

The primary outcome measure is the occurrence of a live birth during the study period. Safety measures will be the number and type of reported adverse events in subjects and offspring. (NCT00719186)
Timeframe: as few as 5 months, up to 16 months

InterventionParticipants (Count of Participants)
Arm A: Clomiphene Citrate72
Arm B: Letrozole103

Number of Ovulations

(NCT00719186)
Timeframe: as few as 5 months, up to 16 months

Interventionovulations (Number)
Arm A: Clomiphene Citrate331
Arm B: Letrozole388

Number of Pregnancy

(NCT00719186)
Timeframe: as few as 5 months, up to 16 months

InterventionParticipants (Count of Participants)
Arm A: Clomiphene Citrate103
Arm B: Letrozole154

Number of Serious Adverse Events

(NCT00719186)
Timeframe: as few as 5 months, up to 16 months

Interventionevents (Number)
Arm A: Clomiphene Citrate13
Arm B: Letrozole22

Neonatal Complication Rate

(NCT00719186)
Timeframe: September 2008 - December 2011

,
Interventionparticipants (Number)
Neonatal jaundiceNeonatal respiratory distress syndromeNeonatal hospitalization >3 daysIntrauterine growth restrictionNeonatal infectinMinor birth defectOther complicationCongenital anomalyNeonatal death
Arm A: Clomiphene Citrate1724120412
Arm B: Letrozole2774521541

Clinical Pregnancy

Clinical Pregnancy: an intrauterine pregnancy with fetal heart motion determined by ultrasonography; No Clinical Pregnancy: no intrauterine pregnancy with fetal heart motion determined by ultrasonography (NCT02802865)
Timeframe: 6-7 weeks after treatment

InterventionParticipants (Count of Participants)
Letrozole1
Letrozole + Clomiphene3

Conception

Conception: a positive serum or urinary test of hCG; No conception: Neither a positive serum or urinary test of hCG (NCT02802865)
Timeframe: 5 weeks after treatment

InterventionParticipants (Count of Participants)
Letrozole3
Letrozole + Clomiphene4

Endometrial Thickness

Thickness of endometrial lining assessed by ultrasound (NCT02802865)
Timeframe: Cycle day 12-14

Interventionmm (Mean)
Letrozole6.2
Letrozole + Clomiphene8.3

Live Birth

Live Birth: delivery of a live infant; No Live Birth: no delivery of a live infant (NCT02802865)
Timeframe: 9-10 months after treatment

InterventionParticipants (Count of Participants)
Letrozole1
Letrozole + Clomiphene3

Multiple Gestation

Multiple Gestation: an intrauterine pregnancy with multiple fetal heart rates determined by ultrasonography; No Multiple Gestation: either no intrauterine pregnancy, or an intrauterine pregnancy with a single fetal heart rate determined by ultrasonography (NCT02802865)
Timeframe: 9-10 months after treatment

InterventionParticipants (Count of Participants)
Letrozole0
Letrozole + Clomiphene0

Number of Developing Follicles

Number of follicles measuring > 10mm on ultrasound (NCT02802865)
Timeframe: Cycle day 12-14

Interventionfollicles (Median)
Letrozole0
Letrozole + Clomiphene1

Number of Participants Achieving Ovulation Measured by Mid-luteal Progesterone Level

Ovulation: mid-luteal progesterone > /=3 ng/mL. No ovulation: mid-luteal progesterone <3ng/mL. (NCT02802865)
Timeframe: 7 days following LH surge or at cycle day 21 if no LH surge was detected

InterventionParticipants (Count of Participants)
Letrozole15
Letrozole + Clomiphene27

Pregnancy Loss

Pregnancy Loss: any pregnancy loss including biochemical pregnancy, ectopic pregnancy, and miscarriage; No Pregnancy Loss: no pregnancy loss including biochemical pregnancy, ectopic pregnancy, or miscarriage. (NCT02802865)
Timeframe: 9-10 months after treatment

InterventionParticipants (Count of Participants)
Letrozole2
Letrozole + Clomiphene1

Size of Largest Developing Follicle

Size of largest follicle on ultrasound (NCT02802865)
Timeframe: Cycle day 12-14

Interventionmm (Median)
Letrozole10
Letrozole + Clomiphene16

Live Birth Rate

(NCT01044862)
Timeframe: Participants were followed for the duration of their treatment and, if pregnant through 6 weeks post-delivery, up to 66 weeks

Interventionparticipants (Number)
Aromatase Inhibitors (AI)56
Clomiphene Citrate (CC)70
Follicle Stimulating Hormone (FSH)97

Multiple Gestation Rate Following Recruitment of Multiple Follicular Development With an AI, as Compared to CC and FSH.

(NCT01044862)
Timeframe: Participants were followed for the duration of their treatment and, if pregnant through 6 weeks post-delivery, up to 66 weeks

Interventionnumber of multiples (Number)
Aromatase Inhibitors (AI)9
Clomiphene Citrate (CC)8
Follicle Stimulating Hormone (FSH)34

Rate of Pregnancy Obtained

(NCT01044862)
Timeframe: Participants were followed for the duration of their treatment and, if pregnant through 6 weeks post-delivery, up to 66 weeks

Interventionparticipants (Number)
Aromatase Inhibitors (AI)85
Clomiphene Citrate (CC)106
Follicle Stimulating Hormone (FSH)140

Time to Pregnancy

(NCT01044862)
Timeframe: Participants were followed for the duration of their treatment and, if pregnant through 6 weeks post-delivery, up to 66 weeks

Interventiondays (Mean)
Aromatase Inhibitors (AI)67.2
Clomiphene Citrate (CC)67.4
Follicle Stimulating Hormone (FSH)62.3

Endometrial Thickness

(NCT01909141)
Timeframe: 3 months

Interventionmm (Mean)
Arm 1:Letrozole-pioglitazone -Metformin Group10.56
Arm 2: Clomiphene Citrate-pioglitazone-metformin9.68

Number of Follicles>18mm.

(NCT01909141)
Timeframe: 3 months

Interventionfollicles (Mean)
Arm 1:Letrozole-pioglitazone -Metformin Group1.44
Arm 2: Clomiphene Citrate-pioglitazone-metformin1.5

Ovulation Rate

(NCT01909141)
Timeframe: 3 months

Interventionpercentage of all cycles (Number)
Arm 1:Letrozole-pioglitazone -Metformin Group93
Arm 2: Clomiphene Citrate-pioglitazone-metformin108

Pregnancy Rate

(NCT01909141)
Timeframe: 3 months

Interventionparticipants (Number)
Arm 1:Letrozole-pioglitazone -Metformin Group28
Arm 2: Clomiphene Citrate-pioglitazone-metformin24

Safety of Pioglitazone as Regards Serum Creatinine

serum creatinine was measured at the end of the study period (after 3 months) in both groups. (NCT01909141)
Timeframe: 3 months

Interventionmg/dL (Mean)
Arm 1:Letrozole-pioglitazone -Metformin Group0.62
Arm 2: Clomiphene Citrate-pioglitazone-metformin0.57

Number of Participants With a Positive LH Test

Urine ovulation tests assessed (NCT01999569)
Timeframe: Cycle days 10-18

InterventionParticipants (Count of Participants)
Control9
Letrozole Treatment Cycle10

Number of Participants With Follicular Development

Ovulation; elevated progesterone (NCT01999569)
Timeframe: Cycle day 12

InterventionParticipants (Count of Participants)
Control10
Letrozole Treatment Cycle10

Number of Participants With Progesterone Level Greater Than 1.5 ng/mL

Serum progesterone ng/mL drawn during cycle days twelve through 22 (NCT01999569)
Timeframe: Cycle days 12-22

InterventionParticipants (Count of Participants)
Control9
Letrozole Treatment Cycle10

Percentage of Participants With Ovulation Detected by Ultrasound

Ovulation detected by ultrasound was defined as the percentage of a participants with ovulation detected by ultrasound, defined as the dominant follicle and its subsequent collapse. If a dominant follicle was not observed by day 21 after menses, the ovulation induction was considered to be a failure. (NCT00427700)
Timeframe: cycle day 14-20

Interventionpercentage of participants (Number)
Clomiphene52.5
Raloxifene40.4

Serum Levels of Progesterone

The level of serum progesterone that indicated ovulation was considered to be 3 ng/mL or greater, on days 8 to 10 after ovulation. (NCT00427700)
Timeframe: 8-10 days after ovulation

Interventionng/mL (Mean)
Clomiphene26.1
Raloxiphene40

Pregnancy Success Rate

Percentage of women in each arm who became pregnant within the study time frame. (NCT01279200)
Timeframe: 3 menstrual/treatment cycles (approximately 28-33 days each)

Interventionpercentage of participants (Number)
Urinary LH Kits75
Midcycle Ultrasound + hCG Injection25

Time to Conception, Measured in Cycles

Cycles means treatment/menstrual cycles, approximately 28-33 days. (NCT01279200)
Timeframe: 3 menstrual/treatment cycles, or upon conception, whichever comes first

Interventionmenstrual cycles (Mean)
Urinary LH Kits1.83
Midcycle Ultrasound + hCG Injection1

Reviews

44 reviews available for letrozole and Infertility, Female

ArticleYear
Live birth after letrozole as an adjunct to follicle-stimulating hormone versus follicle-stimulating hormone alone for ovarian stimulation in in vitro fertilisation cycles-study protocol for a randomised controlled trial.
    Trials, 2022, Apr-01, Volume: 23, Issue:1

    Topics: Drug Therapy, Combination; Female; Fertilization in Vitro; Follicle Stimulating Hormone; Humans; Inf

2022
Ovarian stimulation strategies for intrauterine insemination in couples with unexplained infertility: a systematic review and individual participant data meta-analysis.
    Human reproduction update, 2022, 08-25, Volume: 28, Issue:5

    Topics: Clomiphene; Female; Fertility Agents, Female; Gonadotropins; Humans; Infertility; Infertility, Femal

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2022, 09-27, Volume: 9

    Topics: Abortion, Spontaneous; Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2022
Letrozole: Pharmacology, toxicity and potential therapeutic effects.
    Life sciences, 2022, Dec-01, Volume: 310

    Topics: Aromatase Inhibitors; Breast Neoplasms; Estrogens; Female; Humans; Infertility, Female; Letrozole; N

2022
Letrozole Compared With Clomiphene Citrate for Polycystic Ovarian Syndrome: A Systematic Review and Meta-analysis.
    Obstetrics and gynecology, 2023, 03-01, Volume: 141, Issue:3

    Topics: Clomiphene; Female; Fertility Agents, Female; Humans; Infertility, Female; Letrozole; Live Birth; Ov

2023
First-line ovulation induction for polycystic ovary syndrome: an individual participant data meta-analysis.
    Human reproduction update, 2019, 11-05, Volume: 25, Issue:6

    Topics: Birth Rate; Clomiphene; Female; Fertility Agents, Female; Gonadotropins; Humans; Infertility, Female

2019
Adjuvant treatment strategies in ovarian stimulation for poor responders undergoing IVF: a systematic review and network meta-analysis.
    Human reproduction update, 2020, 02-28, Volume: 26, Issue:2

    Topics: Clomiphene; Combined Modality Therapy; Controlled Clinical Trials as Topic; Drug Resistance; Female;

2020
Adjuvant treatment strategies in ovarian stimulation for poor responders undergoing IVF: a systematic review and network meta-analysis.
    Human reproduction update, 2020, 02-28, Volume: 26, Issue:2

    Topics: Clomiphene; Combined Modality Therapy; Controlled Clinical Trials as Topic; Drug Resistance; Female;

2020
Adjuvant treatment strategies in ovarian stimulation for poor responders undergoing IVF: a systematic review and network meta-analysis.
    Human reproduction update, 2020, 02-28, Volume: 26, Issue:2

    Topics: Clomiphene; Combined Modality Therapy; Controlled Clinical Trials as Topic; Drug Resistance; Female;

2020
Adjuvant treatment strategies in ovarian stimulation for poor responders undergoing IVF: a systematic review and network meta-analysis.
    Human reproduction update, 2020, 02-28, Volume: 26, Issue:2

    Topics: Clomiphene; Combined Modality Therapy; Controlled Clinical Trials as Topic; Drug Resistance; Female;

2020
A review of the physiology behind letrozole applications in infertility: are current protocols optimal?
    Journal of assisted reproduction and genetics, 2020, Volume: 37, Issue:9

    Topics: Androgens; Aromatase Inhibitors; Breast Neoplasms; Estradiol; Female; Follicle Stimulating Hormone;

2020
Comparison of clomiphene and letrozole for superovulation in patients with unexplained infertility undergoing intrauterine insemination: A systematic review and meta-analysis.
    Medicine, 2020, Jul-31, Volume: 99, Issue:31

    Topics: Clomiphene; Female; Fertility Agents, Female; Humans; Infertility, Female; Insemination, Artificial;

2020
Whether Letrozole could reduce the incidence of early ovary hyperstimulation syndrome after assisted reproductive technology? A systematic review and meta-analysis.
    Reproductive health, 2020, Nov-20, Volume: 17, Issue:1

    Topics: Aromatase Inhibitors; Female; Humans; Incidence; Infertility, Female; Letrozole; Ovarian Hyperstimul

2020
Risk of foetal harm with letrozole use in fertility treatment: a systematic review and meta-analysis.
    Human reproduction update, 2021, 04-21, Volume: 27, Issue:3

    Topics: Clomiphene; Female; Fertility Agents, Female; Humans; Infant, Newborn; Infertility, Female; Letrozol

2021
Stimulated cycle versus artificial cycle for frozen embryo transfer in patients with polycystic ovary syndrome: a Meta-analysis.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2021, Volume: 37, Issue:4

    Topics: Abortion, Spontaneous; Aromatase Inhibitors; Cryopreservation; Embryo Implantation; Embryo Transfer;

2021
Higher ovulation rate with letrozole as compared with clomiphene citrate in infertile women with polycystic ovary syndrome: a systematic review and meta-analysis.
    Hormones (Athens, Greece), 2021, Volume: 20, Issue:3

    Topics: Clomiphene; Female; Fertility Agents, Female; Humans; Infertility, Female; Letrozole; Ovulation Indu

2021
Letrozole for Female Infertility.
    Frontiers in endocrinology, 2021, Volume: 12

    Topics: Aromatase Inhibitors; Female; Humans; Infertility, Female; Letrozole; Treatment Outcome

2021
Polycystic ovarian syndrome and infertility: overview and insights of the putative treatments.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2021, Volume: 37, Issue:10

    Topics: Anti-Mullerian Hormone; Bariatric Surgery; Clomiphene; Female; Gonadotropins; Humans; Infertility, F

2021
In vitro fertilization treatments with the use of clomiphene citrate or letrozole.
    Fertility and sterility, 2017, Volume: 108, Issue:4

    Topics: Clomiphene; Drug Therapy, Combination; Female; Fertility Agents, Female; Fertilization in Vitro; Gon

2017
Letrozole versus clomiphene citrate in polycystic ovary syndrome: a meta-analysis of randomized controlled trials.
    Archives of gynecology and obstetrics, 2018, Volume: 297, Issue:5

    Topics: Clomiphene; Female; Fertility Agents, Female; Humans; Infertility, Female; Letrozole; Live Birth; Ov

2018
Aromatase inhibitors (letrozole) for subfertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2018, 05-24, Volume: 5

    Topics: Abortion, Spontaneous; Anastrozole; Aromatase Inhibitors; Birth Rate; Clomiphene; Coitus; Female; Fe

2018
Pharmacology of medications used for ovarian stimulation.
    Best practice & research. Clinical endocrinology & metabolism, 2019, Volume: 33, Issue:1

    Topics: Clomiphene; Female; Fertility Agents, Female; Gonadotropin-Releasing Hormone; Gonadotropins; Humans;

2019
Letrozole and Unexplained Infertility: A Contemporary Meta-analysis.
    Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC, 2019, Volume: 41, Issue:6

    Topics: Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Female; Humans; Infertility, Female; Let

2019
Letrozole versus laparoscopic ovarian drilling in clomiphene citrate-resistant women with polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials.
    Reproductive biology and endocrinology : RB&E, 2019, Feb-06, Volume: 17, Issue:1

    Topics: Aromatase Inhibitors; Birth Rate; Clomiphene; Drug Resistance; Female; Fertility Agents, Female; Hum

2019
Letrozole Compared With Clomiphene Citrate for Unexplained Infertility: A Systematic Review and Meta-analysis.
    Obstetrics and gynecology, 2019, Volume: 133, Issue:3

    Topics: Abortion, Spontaneous; Aromatase Inhibitors; Clomiphene; Estradiol; Female; Fertility Agents, Female

2019
Aromatase inhibitors for subfertile women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2014, Feb-24, Issue:2

    Topics: Anastrozole; Aromatase Inhibitors; Birth Rate; Clomiphene; Coitus; Female; Fertility Agents, Female;

2014
Letrozole versus clomiphene citrate for unexplained infertility: a systematic review and meta-analysis.
    The journal of obstetrics and gynaecology research, 2014, Volume: 40, Issue:5

    Topics: Abortion, Spontaneous; Bias; Clomiphene; Endometrium; Estradiol; Female; Follicle Stimulating Hormon

2014
Endocrine and reproductive effects of polycystic ovarian syndrome.
    Obstetrics and gynecology clinics of North America, 2015, Volume: 42, Issue:1

    Topics: Adult; Clomiphene; Female; Fertility Agents, Female; Fertilization in Vitro; Humans; Infertility, Fe

2015
The use of aromatase inhibitors for ovulation induction.
    Current opinion in obstetrics & gynecology, 2015, Volume: 27, Issue:3

    Topics: Adult; Aromatase Inhibitors; Birth Rate; Clomiphene; Coitus; Female; Humans; Infertility, Female; Le

2015
Novel strategies in the management of polycystic ovary syndrome.
    Minerva endocrinologica, 2015, Volume: 40, Issue:3

    Topics: Adult; Clomiphene; Contraceptives, Oral, Combined; Female; Fertility Agents, Female; Fertilization i

2015
Random-start ovarian stimulation in patients with cancer.
    Current opinion in obstetrics & gynecology, 2015, Volume: 27, Issue:3

    Topics: Adult; Aromatase Inhibitors; Chorionic Gonadotropin; Cryopreservation; Female; Fertility Preservatio

2015
Letrozole versus clomiphene citrate in polycystic ovary syndrome: systematic review and meta-analysis.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2015, Volume: 31, Issue:12

    Topics: Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Female; Humans; Infertility, Female; Let

2015
Treatment strategies for the infertile polycystic ovary syndrome patient.
    Women's health (London, England), 2015, Volume: 11, Issue:6

    Topics: Anovulation; Antineoplastic Agents; Clomiphene; Drug Therapy, Combination; Female; Fertility Agents,

2015
The benefits of other treatments than in vitro fertilization to aid conception in minimal and mild endometriosis.
    Minerva ginecologica, 2016, Volume: 68, Issue:6

    Topics: Clomiphene; Endometriosis; Female; Fertility Agents, Female; Fertilization in Vitro; Humans; Inferti

2016
Mono-ovulation in women with polycystic ovary syndrome: a clinical review on ovulation induction.
    Reproductive biomedicine online, 2016, Volume: 32, Issue:6

    Topics: Adult; Anovulation; Body Weight; Clomiphene; Female; Fertility Agents, Female; Gonadotropins; Humans

2016
The management of anovulatory infertility in women with polycystic ovary syndrome: an analysis of the evidence to support the development of global WHO guidance.
    Human reproduction update, 2016, Volume: 22, Issue:6

    Topics: Anovulation; Aromatase Inhibitors; Clomiphene; Consensus; Female; Fertility Agents, Female; Fertiliz

2016
Oocyte cryopreservation for fertility preservation in women with cancer.
    Current opinion in endocrinology, diabetes, and obesity, 2016, Volume: 23, Issue:6

    Topics: Cryopreservation; Estradiol; Female; Fertility Preservation; Humans; Infertility, Female; Letrozole;

2016
Ovulation induction in polycystic ovary syndrome: Current options.
    Best practice & research. Clinical obstetrics & gynaecology, 2016, Volume: 37

    Topics: Anovulation; Anti-Obesity Agents; Aromatase Inhibitors; Bariatric Surgery; Clomiphene; Diet Therapy;

2016
Treatment strategies for women with WHO group II anovulation: systematic review and network meta-analysis
    BMJ (Clinical research ed.), 2017, 01-31, Volume: 356

    Topics: Anovulation; Clomiphene; Drug Therapy, Combination; Female; Humans; Infertility, Female; Letrozole;

2017
Aromatase inhibitors for female infertility: a systematic review of the literature.
    Reproductive biomedicine online, 2009, Volume: 19, Issue:4

    Topics: Adult; Anastrozole; Aromatase Inhibitors; Clomiphene; Female; Fertilization in Vitro; Gonadotropins;

2009
Fertility preservation in women with breast cancer.
    Clinical obstetrics and gynecology, 2010, Volume: 53, Issue:4

    Topics: Aromatase Inhibitors; Breast Neoplasms; Counseling; Cryopreservation; Embryo, Mammalian; Female; Fer

2010
Reproductive impact of polycystic ovary syndrome.
    Current opinion in endocrinology, diabetes, and obesity, 2012, Volume: 19, Issue:6

    Topics: Abortion, Spontaneous; Clomiphene; Female; Fertilization in Vitro; Humans; Infant, Newborn; Infertil

2012
Polycystic ovarian syndrome management options.
    Obstetrics and gynecology clinics of North America, 2012, Volume: 39, Issue:4

    Topics: Clomiphene; Contraceptives, Oral, Hormonal; Estrogen Antagonists; Exercise; Female; Humans; Infertil

2012
Evaluation and treatment of anovulatory and unexplained infertility.
    Obstetrics and gynecology clinics of North America, 2012, Volume: 39, Issue:4

    Topics: Anovulation; Clomiphene; Diet; Evidence-Based Medicine; Exercise; Female; Fertility Agents, Female;

2012
A new era in ovulation induction.
    Fertility and sterility, 2006, Volume: 85, Issue:2

    Topics: Aromatase Inhibitors; Clomiphene; Drug Therapy, Combination; Female; Fertility Agents, Female; Folli

2006
A new era in ovulation induction.
    Fertility and sterility, 2006, Volume: 85, Issue:2

    Topics: Aromatase Inhibitors; Clomiphene; Drug Therapy, Combination; Female; Fertility Agents, Female; Folli

2006
A new era in ovulation induction.
    Fertility and sterility, 2006, Volume: 85, Issue:2

    Topics: Aromatase Inhibitors; Clomiphene; Drug Therapy, Combination; Female; Fertility Agents, Female; Folli

2006
A new era in ovulation induction.
    Fertility and sterility, 2006, Volume: 85, Issue:2

    Topics: Aromatase Inhibitors; Clomiphene; Drug Therapy, Combination; Female; Fertility Agents, Female; Folli

2006
A new era in ovulation induction.
    Fertility and sterility, 2006, Volume: 85, Issue:2

    Topics: Aromatase Inhibitors; Clomiphene; Drug Therapy, Combination; Female; Fertility Agents, Female; Folli

2006
A new era in ovulation induction.
    Fertility and sterility, 2006, Volume: 85, Issue:2

    Topics: Aromatase Inhibitors; Clomiphene; Drug Therapy, Combination; Female; Fertility Agents, Female; Folli

2006
A new era in ovulation induction.
    Fertility and sterility, 2006, Volume: 85, Issue:2

    Topics: Aromatase Inhibitors; Clomiphene; Drug Therapy, Combination; Female; Fertility Agents, Female; Folli

2006
A new era in ovulation induction.
    Fertility and sterility, 2006, Volume: 85, Issue:2

    Topics: Aromatase Inhibitors; Clomiphene; Drug Therapy, Combination; Female; Fertility Agents, Female; Folli

2006
A new era in ovulation induction.
    Fertility and sterility, 2006, Volume: 85, Issue:2

    Topics: Aromatase Inhibitors; Clomiphene; Drug Therapy, Combination; Female; Fertility Agents, Female; Folli

2006
New advances in ovulation induction.
    Current opinion in obstetrics & gynecology, 2007, Volume: 19, Issue:3

    Topics: Anastrozole; Aromatase Inhibitors; Clomiphene; Estrogen Antagonists; Female; Fertility Agents, Femal

2007
Assisted reproduction and breast cancer.
    Minerva ginecologica, 2007, Volume: 59, Issue:4

    Topics: Algorithms; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cryopreservation; Embr

2007

Trials

77 trials available for letrozole and Infertility, Female

ArticleYear
The efficiency of low-dose letrozole plus clomiphene citrate for ovulation induction in intrauterine insemination cycles: A randomized clinical trial.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2022, Volume: 159, Issue:1

    Topics: Chorionic Gonadotropin; Clomiphene; Female; Fertility Agents, Female; Humans; Infertility, Female; I

2022
Live birth after letrozole as an adjunct to follicle-stimulating hormone versus follicle-stimulating hormone alone for ovarian stimulation in in vitro fertilisation cycles-study protocol for a randomised controlled trial.
    Trials, 2022, Apr-01, Volume: 23, Issue:1

    Topics: Drug Therapy, Combination; Female; Fertilization in Vitro; Follicle Stimulating Hormone; Humans; Inf

2022
The Effect of Clomiphene Citrate and Letrozole in Apoptotic Pathways and Cell Cycle in Human Primary Cumulus Cells and the Protective Effect of Estradiol.
    Reproductive sciences (Thousand Oaks, Calif.), 2022, Volume: 29, Issue:8

    Topics: bcl-2-Associated X Protein; Cell Cycle; Clomiphene; Cumulus Cells; Estradiol; Female; Fertility Agen

2022
Granulocyte colony stimulating factor (GCSF) did not affect the fertility outcomes in women with unexplained infertility after intrauterine insemination: a randomised clinical trial.
    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2022, Volume: 42, Issue:6

    Topics: Abortion, Spontaneous; Clomiphene; Cytokines; Female; Fertility; Granulocyte Colony-Stimulating Fact

2022
A triple-blind, randomized controlled trial, comparing combined letrozole and clomiphene versus only letrozole for ovulation induction in women with polycystic ovarian syndrome.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2023, Volume: 161, Issue:1

    Topics: Clomiphene; Female; Fertility Agents, Female; Humans; Infertility, Female; Letrozole; Ovulation Indu

2023
The impact of letrozole on oocyte quality in assisted reproductive technology (ART); a randomized double-blind clinical trial.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2022, Volume: 38, Issue:12

    Topics: Female; Fertilization in Vitro; Gonadotropins; Humans; Infertility, Female; Letrozole; Oocytes; Ovar

2022
Ovulation induction using sequential letrozole/gonadotrophin in infertile women with PCOS: a randomized controlled trial.
    Reproductive biomedicine online, 2023, Volume: 46, Issue:2

    Topics: Adolescent; Adult; Clomiphene; Female; Fertility Agents, Female; Gonadotropins; Humans; Infertility,

2023
Comparison of Three Ovulation Induction Therapies for Patients With Polycystic Ovary Syndrome and Infertility.
    Journal of clinical pharmacology, 2023, Volume: 63, Issue:12

    Topics: Female; Fertility Agents, Female; Humans; Infertility, Female; Letrozole; Menotropins; Ovulation Ind

2023
Comparing efficacy and safety of stair step protocols for clomiphene citrate and letrozole in ovulation induction for women with polycystic ovary syndrome (PCOS): a randomized controlled clinical trial.
    Journal of medicine and life, 2023, Volume: 16, Issue:5

    Topics: Child; Clomiphene; Female; Fertility Agents, Female; Humans; Infertility, Female; Letrozole; Nitrile

2023
Clomiphene citrate plus letrozole versus clomiphene citrate alone for ovulation induction in infertile women with ovulatory dysfunction: a randomized controlled trial.
    BMC women's health, 2023, Nov-14, Volume: 23, Issue:1

    Topics: Clomiphene; Female; Fertility Agents, Female; Humans; Infertility, Female; Letrozole; Live Birth; Ov

2023
The role of Letrozole (LE) in controlled ovarian stimulation (COS) in patients at high risk to develop ovarian hyper stimulation syndrome (OHSS). A prospective randomized controlled pilot study.
    Journal of gynecology obstetrics and human reproduction, 2020, Volume: 49, Issue:2

    Topics: Adult; Anti-Mullerian Hormone; Aromatase Inhibitors; Female; Fertilization in Vitro; Gonadotropin-Re

2020
Prospective randomized trial comparing efficacy of letrozole step-up protocol with letrozole plus gonadotropins for controlled ovarian stimulation and intrauterine insemination in patients with unexplained infertility.
    Archives of gynecology and obstetrics, 2019, Volume: 300, Issue:6

    Topics: Adult; Aromatase Inhibitors; Female; Gonadotropins; Humans; Infertility, Female; Insemination, Artif

2019
Letrozole and human menopausal gonadotropin for ovulation induction in clomiphene resistance polycystic ovary syndrome patients: A randomized controlled study.
    Medicine, 2020, Volume: 99, Issue:4

    Topics: Abortion, Spontaneous; Adult; Clomiphene; Endometrium; Estradiol; Female; Humans; Infertility, Femal

2020
Comparing the effect of clomiphene citrate and letrozole on ovulation induction in infertile women with polycystic ovary syndrome.
    JPMA. The Journal of the Pakistan Medical Association, 2020, Volume: 70, Issue:2

    Topics: Adult; Aromatase Inhibitors; Clomiphene; Double-Blind Method; Endometrium; Female; Fertility Agents,

2020
A multicenter randomized trial of personalized acupuncture, fixed acupuncture, letrozole, and placebo letrozole on live birth in infertile women with polycystic ovary syndrome.
    Trials, 2020, Mar-04, Volume: 21, Issue:1

    Topics: Abortion, Spontaneous; Acupuncture Therapy; Aromatase Inhibitors; Female; Humans; Infertility, Femal

2020
Letrozole versus clomiphene citrate for ovulation induction in anovulatory women with polycystic ovarian syndrome: A randomized controlled trial.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2021, Volume: 152, Issue:3

    Topics: Adult; Clomiphene; Female; Fertility Agents, Female; Humans; Infertility, Female; Letrozole; Ovulati

2021
Evaluation of the effect of trans-vaginal ovarian needle punctures on women with polycystic ovary syndrome.
    Journal of gynecology obstetrics and human reproduction, 2021, Volume: 50, Issue:5

    Topics: Adult; Aromatase Inhibitors; Clomiphene; Drug Administration Schedule; Drug Resistance; Estrogen Ant

2021
Ovulation induction with clomiphene citrate or letrozole following laparoscopy in infertile women with minimal to mild endometriosis: a prospective randomised controlled trial.
    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2022, Volume: 42, Issue:2

    Topics: Clomiphene; Endometriosis; Female; Fertility Agents, Female; Humans; Infertility, Female; Laparoscop

2022
Concomitant tamoxifen or letrozole for optimal oocyte yield during fertility preservation for breast cancer: the TAmoxifen or Letrozole in Estrogen Sensitive tumors (TALES) randomized clinical trial.
    Journal of assisted reproduction and genetics, 2021, Volume: 38, Issue:9

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cryopreservatio

2021
Comparison of clomiphene citrate and letrozole for ovulation induction in women with polycystic ovary syndrome: a prospective randomized trial.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2017, Volume: 33, Issue:11

    Topics: Adult; Clomiphene; Female; Hormone Antagonists; Humans; Infertility, Female; Letrozole; Nitriles; Ov

2017
[Optimal Ovulation Induction in Polycystic Ovary Syndrome Resistant to Clomiphene Citrate or Letrozole.]
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2016, Volume: 47, Issue:6

    Topics: Clomiphene; Drug Therapy, Combination; Female; Fertility Agents, Female; Humans; Infertility, Female

2016
Double-blind randomized controlled trial of letrozole versus clomiphene citrate in subfertile women with polycystic ovarian syndrome.
    Human reproduction (Oxford, England), 2017, 08-01, Volume: 32, Issue:8

    Topics: Adult; Clomiphene; Double-Blind Method; Female; Fertility Agents, Female; Humans; Infertility, Femal

2017
Intrauterine insemination with ovarian stimulation versus expectant management for unexplained infertility (TUI): a pragmatic, open-label, randomised, controlled, two-centre trial.
    Lancet (London, England), 2018, 02-03, Volume: 391, Issue:10119

    Topics: Administration, Oral; Adult; Clomiphene; Drug Administration Schedule; Female; Fertility Agents, Fem

2018
The VEGF and PEDF levels in the follicular fluid of patients co- treated with LETROZOLE and gonadotropins during the stimulation cycle.
    Reproductive biology and endocrinology : RB&E, 2018, May-29, Volume: 16, Issue:1

    Topics: Adult; Aromatase Inhibitors; Drug Therapy, Combination; Eye Proteins; Female; Follicular Fluid; Gona

2018
Insulin resistance is associated with depression risk in polycystic ovary syndrome.
    Fertility and sterility, 2018, 07-01, Volume: 110, Issue:1

    Topics: Adult; Clomiphene; Depression; Female; Humans; Infertility, Female; Insulin Resistance; Letrozole; P

2018
A randomized controlled trial comparing lifestyle intervention to letrozole for ovulation in women with polycystic ovary syndrome: a study protocol.
    Trials, 2018, Nov-16, Volume: 19, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Diet, Healthy; Exercise; Female; Fertility Agents, Female;

2018
Letrozole-associated controlled ovarian hyperstimulation in breast cancer patients versus conventional controlled ovarian hyperstimulation in infertile patients: assessment of oocyte quality related biomarkers.
    Reproductive biology and endocrinology : RB&E, 2019, Jan-03, Volume: 17, Issue:1

    Topics: Adolescent; Adult; Breast Neoplasms; Cellular Microenvironment; Estradiol; Female; Fertility Preserv

2019
A randomized controlled trial of combination letrozole and clomiphene citrate or letrozole alone for ovulation induction in women with polycystic ovary syndrome.
    Fertility and sterility, 2019, Volume: 111, Issue:3

    Topics: Adolescent; Adult; Age Factors; Biomarkers; Body Mass Index; Clomiphene; Female; Fertility; Fertilit

2019
The effectiveness of inositol and metformin on infertile polycystic ovary syndrome women with resistant to letrozole.
    Archives of gynecology and obstetrics, 2019, Volume: 299, Issue:4

    Topics: Adult; Female; Folic Acid; Humans; Infertility, Female; Inositol; Letrozole; Metformin; Ovulation In

2019
Impact of letrozole versus clomiphene citrate on endometrial receptivity in Iraqi women with polycystic ovarian syndrome.
    Journal of clinical pharmacy and therapeutics, 2019, Volume: 44, Issue:4

    Topics: Adult; Aromatase Inhibitors; Clomiphene; Endometrium; Female; Humans; Infertility, Female; Letrozole

2019
Letrozole usage adjuvant to gonadotropins for ovulation induction for patients with clomiphene citrate failure.
    Archives of gynecology and obstetrics, 2013, Volume: 288, Issue:2

    Topics: Adult; Aromatase Inhibitors; Clomiphene; Drug Therapy, Combination; Endometrium; Estradiol; Female;

2013
Combined letrozole and clomiphene versus letrozole and clomiphene alone in infertile patients with polycystic ovary syndrome.
    Drug design, development and therapy, 2013, Volume: 7

    Topics: Adult; Aromatase Inhibitors; Clomiphene; Drug Therapy, Combination; Female; Fertility Agents, Female

2013
Combined letrozole and clomiphene versus letrozole and clomiphene alone in infertile patients with polycystic ovary syndrome.
    Drug design, development and therapy, 2013, Volume: 7

    Topics: Adult; Aromatase Inhibitors; Clomiphene; Drug Therapy, Combination; Female; Fertility Agents, Female

2013
Combined letrozole and clomiphene versus letrozole and clomiphene alone in infertile patients with polycystic ovary syndrome.
    Drug design, development and therapy, 2013, Volume: 7

    Topics: Adult; Aromatase Inhibitors; Clomiphene; Drug Therapy, Combination; Female; Fertility Agents, Female

2013
Combined letrozole and clomiphene versus letrozole and clomiphene alone in infertile patients with polycystic ovary syndrome.
    Drug design, development and therapy, 2013, Volume: 7

    Topics: Adult; Aromatase Inhibitors; Clomiphene; Drug Therapy, Combination; Female; Fertility Agents, Female

2013
Combined letrozole and clomiphene versus letrozole and clomiphene alone in infertile patients with polycystic ovary syndrome.
    Drug design, development and therapy, 2013, Volume: 7

    Topics: Adult; Aromatase Inhibitors; Clomiphene; Drug Therapy, Combination; Female; Fertility Agents, Female

2013
Combined letrozole and clomiphene versus letrozole and clomiphene alone in infertile patients with polycystic ovary syndrome.
    Drug design, development and therapy, 2013, Volume: 7

    Topics: Adult; Aromatase Inhibitors; Clomiphene; Drug Therapy, Combination; Female; Fertility Agents, Female

2013
Combined letrozole and clomiphene versus letrozole and clomiphene alone in infertile patients with polycystic ovary syndrome.
    Drug design, development and therapy, 2013, Volume: 7

    Topics: Adult; Aromatase Inhibitors; Clomiphene; Drug Therapy, Combination; Female; Fertility Agents, Female

2013
Combined letrozole and clomiphene versus letrozole and clomiphene alone in infertile patients with polycystic ovary syndrome.
    Drug design, development and therapy, 2013, Volume: 7

    Topics: Adult; Aromatase Inhibitors; Clomiphene; Drug Therapy, Combination; Female; Fertility Agents, Female

2013
Combined letrozole and clomiphene versus letrozole and clomiphene alone in infertile patients with polycystic ovary syndrome.
    Drug design, development and therapy, 2013, Volume: 7

    Topics: Adult; Aromatase Inhibitors; Clomiphene; Drug Therapy, Combination; Female; Fertility Agents, Female

2013
An effective alternative to only gonadotrophin for controlled ovarian stimulation in unexplained infertility patients undergoing intra-uterine insemination: a clinical trial.
    Journal of the Indian Medical Association, 2013, Volume: 111, Issue:9

    Topics: Adult; Aromatase Inhibitors; Drug Therapy, Combination; Female; Follicle Stimulating Hormone; Humans

2013
Letrozole versus clomiphene for infertility in the polycystic ovary syndrome.
    The New England journal of medicine, 2014, Jul-10, Volume: 371, Issue:2

    Topics: Adult; Clomiphene; Double-Blind Method; Female; Fertility Agents, Female; Humans; Infertility, Femal

2014
Letrozole versus clomiphene for infertility in the polycystic ovary syndrome.
    The New England journal of medicine, 2014, Jul-10, Volume: 371, Issue:2

    Topics: Adult; Clomiphene; Double-Blind Method; Female; Fertility Agents, Female; Humans; Infertility, Femal

2014
Letrozole versus clomiphene for infertility in the polycystic ovary syndrome.
    The New England journal of medicine, 2014, Jul-10, Volume: 371, Issue:2

    Topics: Adult; Clomiphene; Double-Blind Method; Female; Fertility Agents, Female; Humans; Infertility, Femal

2014
Letrozole versus clomiphene for infertility in the polycystic ovary syndrome.
    The New England journal of medicine, 2014, Jul-10, Volume: 371, Issue:2

    Topics: Adult; Clomiphene; Double-Blind Method; Female; Fertility Agents, Female; Humans; Infertility, Femal

2014
Letrozole versus clomiphene for infertility in the polycystic ovary syndrome.
    The New England journal of medicine, 2014, Jul-10, Volume: 371, Issue:2

    Topics: Adult; Clomiphene; Double-Blind Method; Female; Fertility Agents, Female; Humans; Infertility, Femal

2014
Letrozole versus clomiphene for infertility in the polycystic ovary syndrome.
    The New England journal of medicine, 2014, Jul-10, Volume: 371, Issue:2

    Topics: Adult; Clomiphene; Double-Blind Method; Female; Fertility Agents, Female; Humans; Infertility, Femal

2014
Letrozole versus clomiphene for infertility in the polycystic ovary syndrome.
    The New England journal of medicine, 2014, Jul-10, Volume: 371, Issue:2

    Topics: Adult; Clomiphene; Double-Blind Method; Female; Fertility Agents, Female; Humans; Infertility, Femal

2014
Letrozole versus clomiphene for infertility in the polycystic ovary syndrome.
    The New England journal of medicine, 2014, Jul-10, Volume: 371, Issue:2

    Topics: Adult; Clomiphene; Double-Blind Method; Female; Fertility Agents, Female; Humans; Infertility, Femal

2014
Letrozole versus clomiphene for infertility in the polycystic ovary syndrome.
    The New England journal of medicine, 2014, Jul-10, Volume: 371, Issue:2

    Topics: Adult; Clomiphene; Double-Blind Method; Female; Fertility Agents, Female; Humans; Infertility, Femal

2014
Effects of combining low‑dose aspirin with a Chinese patent medicine on follicular blood flow and pregnancy outcome.
    Molecular medicine reports, 2014, Volume: 10, Issue:5

    Topics: Adult; Aspirin; Drug Therapy, Combination; Drugs, Chinese Herbal; Endometrium; Female; Fertility Age

2014
[Relationship between letrozole administration during the luteal phase after oocyte retrieval and the early-stage ovarian hyperstimulation syndrome oocurrence].
    Zhonghua fu chan ke za zhi, 2014, Volume: 49, Issue:12

    Topics: Aromatase Inhibitors; Estradiol; Female; Fertilization in Vitro; Humans; Infertility, Female; Letroz

2014
Assessment of multiple intrauterine gestations from ovarian stimulation (AMIGOS) trial: baseline characteristics.
    Fertility and sterility, 2015, Volume: 103, Issue:4

    Topics: Adult; Clomiphene; Female; Fertility Agents, Female; Gonadotropins; Humans; Infertility, Female; Let

2015
Letrozole, Gonadotropin, or Clomiphene for Unexplained Infertility.
    The New England journal of medicine, 2015, Sep-24, Volume: 373, Issue:13

    Topics: Adolescent; Adult; Clomiphene; Female; Fertility Agents, Female; Gonadotropins; Humans; Infertility,

2015
Comparison of letrazole and clomiphene citrate in women with polycystic ovaries undergoing ovarian stimulation.
    JPMA. The Journal of the Pakistan Medical Association, 2015, Volume: 65, Issue:11

    Topics: Adult; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Female; Humans; Infertility, Fema

2015
Effects of Letrozole-HMG and Clomiphene-HMG on Incidence of Luteinized Unruptured Follicle Syndrome in Infertile Women Undergoing Induction Ovulation and Intrauterine Insemination: A Randomised Trial.
    Global journal of health science, 2015, Sep-01, Volume: 8, Issue:4

    Topics: Adult; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Female; Follicular Phase; Humans;

2015
A randomized controlled trial of clomifene citrate, metformin, and pioglitazone versus letrozole, metformin, and pioglitazone for clomifene-citrate-resistant polycystic ovary syndrome.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2016, Volume: 132, Issue:2

    Topics: Adult; Clomiphene; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Egypt; Female; F

2016
Use of letrozole and clomiphene citrate combined with gonadotropins in clomiphene-resistant infertile women with polycystic ovary syndrome: a prospective study.
    Drug design, development and therapy, 2015, Volume: 9

    Topics: Adult; Clomiphene; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fertility Ag

2015
A randomized, single-blind, prospective trial comparing three different gonadotropin doses with or without addition of letrozole during ovulation stimulation in patients with poor ovarian response.
    European journal of obstetrics, gynecology, and reproductive biology, 2016, Volume: 203

    Topics: Adolescent; Adult; Dose-Response Relationship, Drug; Drug Therapy, Combination; Embryo Transfer; Fem

2016
Randomized controlled trial of letrozole, berberine, or a combination for infertility in the polycystic ovary syndrome.
    Fertility and sterility, 2016, Sep-01, Volume: 106, Issue:3

    Topics: Administration, Oral; Adult; Berberine; China; Double-Blind Method; Drug Administration Schedule; Dr

2016
Comparison of acupuncture pretreatment followed by letrozole versus letrozole alone on live birth in anovulatory infertile women with polycystic ovary syndrome: a study protocol for a randomised controlled trial.
    BMJ open, 2016, 10-07, Volume: 6, Issue:10

    Topics: Acupuncture Therapy; Adult; Aromatase Inhibitors; Birth Rate; Clinical Protocols; Electroacupuncture

2016
RETRACTED: Clomiphene citrate or aromatase inhibitors for superovulation in women with unexplained infertility undergoing intrauterine insemination: a prospective randomized trial.
    Fertility and sterility, 2009, Volume: 92, Issue:4

    Topics: Adult; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Female; Humans; Infertility, Fema

2009
Pregnancy outcome after ovulation induction with aromatase inhibitors or clomiphene citrate in unexplained infertility.
    Acta obstetricia et gynecologica Scandinavica, 2009, Volume: 88, Issue:2

    Topics: Abortion, Spontaneous; Adult; Anastrozole; Aromatase Inhibitors; Clomiphene; Female; Fertility Agent

2009
Endometrial and follicular development following letrozole intervention in unexplained infertile patients failed to get pregnant with clomiphene citrate.
    Archives of gynecology and obstetrics, 2009, Volume: 280, Issue:2

    Topics: Adult; Aromatase Inhibitors; Clomiphene; Endometrium; Estradiol; Female; Fertility Agents, Female; H

2009
RETRACTED: Letrozole versus combined metformin and clomiphene citrate for ovulation induction in clomiphene-resistant women with polycystic ovary syndrome: a randomized controlled trial.
    Fertility and sterility, 2010, Volume: 94, Issue:4

    Topics: Adult; Algorithms; Clomiphene; Drug Combinations; Drug Resistance; Female; Fertility Agents, Female;

2010
Use of aromatase inhibitors in poor-responder patients receiving GnRH antagonist protocols.
    Reproductive biomedicine online, 2009, Volume: 19, Issue:4

    Topics: Adult; Aromatase Inhibitors; Chorionic Gonadotropin; Female; Follicle Stimulating Hormone; Gonadotro

2009
Aromatase inhibitors in women with clomiphene citrate resistance: a randomized, double-blind, placebo-controlled trial.
    Fertility and sterility, 2010, Volume: 94, Issue:7

    Topics: Adult; Aromatase Inhibitors; Clomiphene; Double-Blind Method; Drug Resistance; Female; Fertility Age

2010
A comparison of the effect of short-term aromatase inhibitor (letrozole) and GnRH agonist (triptorelin) versus case control on pregnancy rate and symptom and sign recurrence after laparoscopic treatment of endometriosis.
    Archives of gynecology and obstetrics, 2011, Volume: 284, Issue:1

    Topics: Adult; Aromatase Inhibitors; Endometriosis; Female; Gonadotropin-Releasing Hormone; Humans; Infertil

2011
Reproductive outcome after letrozole versus laparoscopic ovarian drilling for clomiphene-resistant polycystic ovary syndrome.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2011, Volume: 113, Issue:3

    Topics: Adult; Anovulation; Aromatase Inhibitors; Clomiphene; Drug Administration Schedule; Drug Resistance;

2011
Extended letrozole regimen versus clomiphene citrate for superovulation in patients with unexplained infertility undergoing intrauterine insemination: a randomized controlled trial.
    Reproductive biology and endocrinology : RB&E, 2011, Jun-21, Volume: 9

    Topics: Adult; Aromatase Inhibitors; Clomiphene; Female; Humans; Infertility, Female; Insemination; Letrozol

2011
Extended letrozole regimen versus clomiphene citrate for superovulation in patients with unexplained infertility undergoing intrauterine insemination: a randomized controlled trial.
    Reproductive biology and endocrinology : RB&E, 2011, Jun-21, Volume: 9

    Topics: Adult; Aromatase Inhibitors; Clomiphene; Female; Humans; Infertility, Female; Insemination; Letrozol

2011
Extended letrozole regimen versus clomiphene citrate for superovulation in patients with unexplained infertility undergoing intrauterine insemination: a randomized controlled trial.
    Reproductive biology and endocrinology : RB&E, 2011, Jun-21, Volume: 9

    Topics: Adult; Aromatase Inhibitors; Clomiphene; Female; Humans; Infertility, Female; Insemination; Letrozol

2011
Extended letrozole regimen versus clomiphene citrate for superovulation in patients with unexplained infertility undergoing intrauterine insemination: a randomized controlled trial.
    Reproductive biology and endocrinology : RB&E, 2011, Jun-21, Volume: 9

    Topics: Adult; Aromatase Inhibitors; Clomiphene; Female; Humans; Infertility, Female; Insemination; Letrozol

2011
Comparison of efficacy of letrozole and clomiphene citrate in ovulation induction in Indian women with polycystic ovarian syndrome.
    Archives of gynecology and obstetrics, 2012, Volume: 285, Issue:3

    Topics: Adult; Chorionic Gonadotropin; Clomiphene; Endometrium; Estradiol; Female; Fertility Agents, Female;

2012
Randomized comparison of superovulation with letrozole vs. clomiphene citrate in an IUI program for women with recently surgically treated minimal to mild endometriosis.
    Acta obstetricia et gynecologica Scandinavica, 2012, Volume: 91, Issue:3

    Topics: Adult; Aromatase Inhibitors; Clomiphene; Drug Administration Schedule; Endometriosis; Female; Fertil

2012
The Pregnancy in Polycystic Ovary Syndrome II (PPCOS II) trial: rationale and design of a double-blind randomized trial of clomiphene citrate and letrozole for the treatment of infertility in women with polycystic ovary syndrome.
    Contemporary clinical trials, 2012, Volume: 33, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Agents; Chi-Square Distribution; Clomiphene; Double-Blind Method;

2012
Comparison of treatment outcomes of infertile women by clomiphene citrate and letrozole with gonadotropins underwent intrauterine insemination.
    Acta medica Iranica, 2012, Volume: 50, Issue:1

    Topics: Adult; Clomiphene; Female; Fertility; Fertility Agents, Female; Gonadotropins; Humans; Infertility,

2012
Comparison of the effects of letrozole and clomiphene citrate for ovulation induction in infertile women with polycystic ovary syndrome.
    Minerva ginecologica, 2012, Volume: 64, Issue:3

    Topics: Adult; Clomiphene; Female; Fertility Agents, Female; Humans; Infertility, Female; Letrozole; Nitrile

2012
Letrozole versus clomiphene citrate for superovulation in Egyptian women with unexplained infertility: a randomized controlled trial.
    Archives of gynecology and obstetrics, 2012, Volume: 286, Issue:6

    Topics: Adult; Chi-Square Distribution; Chorionic Gonadotropin; Clomiphene; Egypt; Endometrium; Endosonograp

2012
Is letrozole superior to clomiphene for ovarian stimulation prior to intrauterine insemination?
    Archives of gynecology and obstetrics, 2013, Volume: 287, Issue:3

    Topics: Adult; Clomiphene; Female; Fertility Agents, Female; Humans; Infertility, Female; Insemination, Arti

2013
Minimal stimulation protocol using letrozole versus microdose flare up GnRH agonist protocol in women with poor ovarian response undergoing ICSI.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2013, Volume: 29, Issue:2

    Topics: Adult; Aromatase Inhibitors; Drug Resistance; Egypt; Estradiol; Female; Fertility Agents, Female; Fe

2013
Efficacy of combined metformin-letrozole in comparison with bilateral ovarian drilling in clomiphene-resistant infertile women with polycystic ovarian syndrome.
    Archives of gynecology and obstetrics, 2013, Volume: 288, Issue:1

    Topics: Adult; Aromatase Inhibitors; Blood Glucose; Clomiphene; Drug Therapy, Combination; Female; Fertility

2013
Aromatase inhibition reduces the dose of gonadotropin required for controlled ovarian hyperstimulation.
    Journal of the Society for Gynecologic Investigation, 2004, Volume: 11, Issue:6

    Topics: Adult; Aromatase Inhibitors; Female; Follicle Stimulating Hormone; Humans; Infertility, Female; Letr

2004
A randomized trial of letrozole versus clomiphene citrate in women undergoing superovulation.
    Fertility and sterility, 2004, Volume: 82, Issue:6

    Topics: Abortion, Spontaneous; Adult; Aromatase Inhibitors; Clomiphene; Endometrium; Female; Fertility Agent

2004
Efficacy of combined metformin-letrozole in comparison with metformin-clomiphene citrate in clomiphene-resistant infertile women with polycystic ovarian disease.
    Human reproduction (Oxford, England), 2006, Volume: 21, Issue:6

    Topics: Adult; Aromatase Inhibitors; Clomiphene; Drug Resistance; Drug Therapy, Combination; Endometrium; Fe

2006
Letrozole vs. clomiphene citrate in patients with ovulatory infertility.
    Fertility and sterility, 2006, Volume: 85, Issue:4

    Topics: Administration, Oral; Adult; Anovulation; Clomiphene; Endometriosis; Female; Fertility Agents, Femal

2006
Aromatase inhibitors in ovarian stimulation for IVF/ICSI: a pilot study.
    Reproductive biomedicine online, 2006, Volume: 13, Issue:2

    Topics: Adult; Aromatase Inhibitors; Drug Therapy, Combination; Female; Fertilization in Vitro; Follicle Sti

2006
Letrozole versus human menopausal gonadotrophin in women undergoing intrauterine insemination.
    Reproductive biomedicine online, 2006, Volume: 13, Issue:2

    Topics: Adult; Aromatase Inhibitors; Endometrium; Female; Follicular Phase; Humans; Infertility, Female; Ins

2006
Comparison of the efficacy of the aromatase inhibitor letrozole and clomiphene citrate as adjuvants to recombinant follicle-stimulating hormone in controlled ovarian hyperstimulation: a prospective, randomized, blinded clinical trial.
    Fertility and sterility, 2006, Volume: 86, Issue:5

    Topics: Adult; Aromatase Inhibitors; Chemotherapy, Adjuvant; Clomiphene; Drug Combinations; Female; Fertilit

2006
Role of aromatase inhibitor in ovulation induction in patients with poor response to clomiphene citrate.
    The journal of obstetrics and gynaecology research, 2006, Volume: 32, Issue:5

    Topics: Adult; Aromatase Inhibitors; Clomiphene; Female; Humans; Infertility, Female; Letrozole; Nitriles; O

2006
Follicular phase dynamics with combined aromatase inhibitor and follicle stimulating hormone treatment.
    The Journal of clinical endocrinology and metabolism, 2007, Volume: 92, Issue:3

    Topics: Adult; Aromatase Inhibitors; Dose-Response Relationship, Drug; Drug Therapy, Combination; Endometriu

2007
Management of poor responders: can outcomes be improved with a novel gonadotropin-releasing hormone antagonist/letrozole protocol?
    Fertility and sterility, 2008, Volume: 89, Issue:1

    Topics: Adult; Aromatase Inhibitors; Chorionic Gonadotropin; Dose-Response Relationship, Drug; Drug Administ

2008
Randomized controlled trial of three doses of letrozole for ovulation induction in patients with unexplained infertility.
    Reproductive biomedicine online, 2007, Volume: 14, Issue:5

    Topics: Adult; Aromatase Inhibitors; Female; Humans; Infertility, Female; Letrozole; Nitriles; Ovulation Ind

2007
RETRACTED: Anastrozole or letrozole for ovulation induction in clomiphene-resistant women with polycystic ovarian syndrome: a prospective randomized trial.
    Fertility and sterility, 2008, Volume: 89, Issue:5

    Topics: Abortion, Spontaneous; Adult; Anastrozole; Aromatase Inhibitors; Clomiphene; Drug Resistance; Endome

2008
A comparison of letrozole to gonadotropins for ovulation induction in subjects with advanced maternal age: a retrospective pilot study.
    Fertility and sterility, 2008, Volume: 90, Issue:4

    Topics: Adult; Aromatase Inhibitors; Female; Gonadotropins; Humans; Infertility, Female; Letrozole; Middle A

2008
Use of an aromatase inhibitor for induction of ovulation in patients with an inadequate response to clomiphene citrate.
    Fertility and sterility, 2001, Volume: 75, Issue:2

    Topics: Anovulation; Aromatase Inhibitors; Chorionic Gonadotropin; Endometrium; Enzyme Inhibitors; Estradiol

2001

Other Studies

87 other studies available for letrozole and Infertility, Female

ArticleYear
Frozen Embryo Transfer in Mildly Stimulated Cycle With Letrozole Compared to Natural Cycle in Ovulatory Women: A Large Retrospective Study.
    Frontiers in endocrinology, 2021, Volume: 12

    Topics: Adult; Aromatase Inhibitors; Cryopreservation; Embryo Transfer; Female; Humans; Infertility, Female;

2021
Letrozole promotes the expression of integrin αvβ3 and HOXA10 in endometrium of endometriosis.
    Systems biology in reproductive medicine, 2022, Volume: 68, Issue:2

    Topics: Animals; Embryo Implantation; Endometriosis; Endometrium; Female; Homeobox A10 Proteins; Humans; Inf

2022
Emulating a target trial of the comparative effectiveness of clomiphene citrate and letrozole for ovulation induction.
    Human reproduction (Oxford, England), 2022, 04-01, Volume: 37, Issue:4

    Topics: Adolescent; Adult; Child; Clomiphene; Female; Fertility Agents, Female; Humans; Infant, Newborn; Inf

2022
The Effects of Letrozole and Metformin Combined with Targeted Nursing Care on Ovarian Function, LH, and FSH in Infertile Patients with Polycystic Ovary Syndrome.
    Journal of healthcare engineering, 2022, Volume: 2022

    Topics: Female; Follicle Stimulating Hormone; Humans; Infertility, Female; Letrozole; Metformin; Polycystic

2022
Efficacy of Letrozole Combined with Urinary Gonadotropin for Ovulation Induction in Endocrine Abnormal Infertility Patients: A Retrospective Single-Center, Case-Control Study.
    Computational and mathematical methods in medicine, 2022, Volume: 2022

    Topics: Case-Control Studies; Child; Female; Gonadotropins; Humans; Infertility, Female; Letrozole; Menotrop

2022
Comparison of different endometrial preparation protocols on frozen embryo transfer pregnancy outcome in patients with normal ovulation.
    Reproductive biomedicine online, 2022, Volume: 45, Issue:6

    Topics: Cryopreservation; Embryo Transfer; Female; Humans; Infertility, Female; Letrozole; Live Birth; Ovula

2022
Extending letrozole treatment duration is effective in inducing ovulation in women with polycystic ovary syndrome and letrozole resistance.
    Fertility and sterility, 2023, Volume: 119, Issue:1

    Topics: Clomiphene; Duration of Therapy; Female; Fertility Agents, Female; Humans; Infertility, Female; Letr

2023
Effect of different timing of letrozole initiation on pregnancy outcome in polycystic ovary syndrome.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Clomiphene; Female; Fertility Agents, Female; Humans; Infertility, Female; Letrozole; Nitriles; Poly

2022
Effect of different timing of letrozole initiation on pregnancy outcome in polycystic ovary syndrome.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Clomiphene; Female; Fertility Agents, Female; Humans; Infertility, Female; Letrozole; Nitriles; Poly

2022
Effect of different timing of letrozole initiation on pregnancy outcome in polycystic ovary syndrome.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Clomiphene; Female; Fertility Agents, Female; Humans; Infertility, Female; Letrozole; Nitriles; Poly

2022
Effect of different timing of letrozole initiation on pregnancy outcome in polycystic ovary syndrome.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Clomiphene; Female; Fertility Agents, Female; Humans; Infertility, Female; Letrozole; Nitriles; Poly

2022
Ovarian Response can be Predicted in Women with PCOS who have Ovulation Induction with Letrozole.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2023, Volume: 33, Issue:2

    Topics: Cohort Studies; Female; Fertility Agents, Female; Follicle Stimulating Hormone; Humans; Infertility,

2023
Development and evaluation of novel krill oil-based clomiphene microemulsion as a therapeutic strategy for PCOS treatment.
    Drug delivery and translational research, 2023, Volume: 13, Issue:9

    Topics: Animals; Clomiphene; Euphausiacea; Female; Humans; Infertility, Female; Insulin Resistance; Letrozol

2023
Letrozole cotreatment improves the follicular output rate in high-body-mass-index women with polycystic ovary syndrome undergoing IVF treatment.
    Frontiers in endocrinology, 2023, Volume: 14

    Topics: Body Mass Index; Female; Fertilization in Vitro; Humans; Infertility, Female; Letrozole; Polycystic

2023
Synergistic action of carvedilol and clomiphene in mitigating the behavioral phenotypes of letrozole-model of PCOS rats by modulating the NRF2/NFKB pathway.
    Life sciences, 2023, Jul-01, Volume: 324

    Topics: Acetylcholine; Animals; Carvedilol; Catalase; Clomiphene; Esterases; Female; Fertility Agents, Femal

2023
Ovulation induction with letrozole and dexamethasone in infertile patients with letrozole-resistant polycystic ovary syndrome.
    Journal of assisted reproduction and genetics, 2023, Volume: 40, Issue:6

    Topics: Clomiphene; Dexamethasone; Female; Fertility Agents, Female; Humans; Infertility, Female; Letrozole;

2023
Association between follicle size, endometrial thickness, and types of ovarian stimulation (Clomiphene citrate and Letrozole) with biochemical pregnancy rate in women undergone intrauterine insemination.
    BMC research notes, 2023, Oct-24, Volume: 16, Issue:1

    Topics: Case-Control Studies; Clomiphene; Female; Fertility Agents, Female; Humans; Infertility, Female; Ins

2023
Impact of 2.5 mg versus 5 mg letrozole co-treatment in an antagonist protocol for IVF: a retrospective study.
    Frontiers in endocrinology, 2023, Volume: 14

    Topics: China; Female; Fertilization in Vitro; Gonadotropin-Releasing Hormone; Humans; Infant, Newborn; Infe

2023
A comparison between a combination of letrozole and clomiphene citrate versus gonadotropins for ovulation induction in infertile patients with clomiphene citrateresistant polycystic ovary syndrome - a retrospective study.
    Ginekologia polska, 2020, Volume: 91, Issue:4

    Topics: Adult; Clomiphene; Dose-Response Relationship, Drug; Female; Fertility Agents, Female; Gonadotropins

2020
The impact of letrozole administration on oocyte morphology in breast cancer patients undergoing fertility preservation.
    JBRA assisted reproduction, 2020, 07-14, Volume: 24, Issue:3

    Topics: Adult; Antineoplastic Agents; Breast Neoplasms; Cell Shape; Cryopreservation; Female; Fertility Pres

2020
Pregnancy registry: three-year follow-up of children conceived from letrozole, clomiphene, or gonadotropins.
    Fertility and sterility, 2020, Volume: 113, Issue:5

    Topics: Adult; Age Factors; Child Behavior; Child Development; Child, Preschool; Clomiphene; Cognition; Fema

2020
Successful live birth in a woman with resistant ovary syndrome treated with letrozole and HMG: A case report.
    Medicine, 2020, Volume: 99, Issue:20

    Topics: Adult; Aromatase Inhibitors; Drug Therapy, Combination; Female; Gonadotropins; Humans; Infertility,

2020
The leaf aqueous extract of Myrianthus arboreus P. Beauv. (Cecropiaceae) improved letrozole-induced polycystic ovarian syndrome associated conditions and infertility in female Wistar rats.
    BMC complementary medicine and therapies, 2020, Sep-11, Volume: 20, Issue:1

    Topics: Animals; Cameroon; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Infertility, Fe

2020
Do lipid parameters change during clomiphene citrate or letrozole therapy in women being treated for infertility? A pilot study.
    European journal of obstetrics, gynecology, and reproductive biology, 2021, Volume: 257

    Topics: Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Female; Humans; Infertility; Infertility

2021
Effects of letrozole or tamoxifen coadministered with a standard stimulation protocol on fertility preservation among breast cancer patients.
    Journal of assisted reproduction and genetics, 2021, Volume: 38, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Fertili

2021
Application of Pulsed Rhythmic Drug Administration to Ovulation Induction Therapy in PCOS Patients with Clomiphene-Resistance: a Retrospective Research.
    Reproductive sciences (Thousand Oaks, Calif.), 2021, Volume: 28, Issue:11

    Topics: Adult; Aromatase Inhibitors; Clomiphene; Drug Administration Routes; Drug Resistance; Female; Fertil

2021
Uterine anomalies in cell proliferation, energy homeostasis and oxidative stress in PCOS hamsters, M. auratus: Therapeutic potentials of melatonin.
    Life sciences, 2021, Sep-15, Volume: 281

    Topics: Animals; Aromatase Inhibitors; Blood Glucose; Cell Proliferation; Cricetinae; Disease Models, Animal

2021
Comparison of the efficacy of letrozole stair-step protocol with clomiphene citrate stair-step protocol in the management of clomiphene citrate-resistant polycystic ovary syndrome patients.
    The journal of obstetrics and gynaecology research, 2021, Volume: 47, Issue:11

    Topics: Clomiphene; Female; Fertility Agents, Female; Humans; Infertility, Female; Letrozole; Ovulation Indu

2021
Letrozole as first-line drug for ovulation induction in treatment-naïve infertile polycystic ovarian syndrome women.
    The journal of obstetrics and gynaecology research, 2021, Volume: 47, Issue:10

    Topics: Cohort Studies; Female; Fertility Agents, Female; Humans; Infertility, Female; Letrozole; Ovulation;

2021
Pregnancy and neonatal outcomes following letrozole use in frozen-thawed single embryo transfer cycles.
    Human reproduction (Oxford, England), 2017, 06-01, Volume: 32, Issue:6

    Topics: Abortion, Spontaneous; Aromatase Inhibitors; Blastocyst; Cohort Studies; Cryopreservation; Female; F

2017
Re: Clomiphene citrate and letrozole to reduce follicle-stimulating hormone consumption during ovarian stimulation: systematic review and meta-analysis. T. N. Bechtejew, M. N. Nadai, C. O. Nastri and W. P. Martins. Ultrasound Obstet Gynecol 2017; 50: 315-
    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 2017, Volume: 50, Issue:3

    Topics: Clomiphene; Follicle Stimulating Hormone; Humans; Infertility, Female; Letrozole; Nitriles; Ovulatio

2017
Ovulation induction and controlled ovarian stimulation using letrozole gonadotropin combination: A single center retrospective cohort study.
    European journal of obstetrics, gynecology, and reproductive biology, 2017, Volume: 218

    Topics: Adult; Drug Therapy, Combination; Endometriosis; Female; Fertility Agents, Female; Follicle Stimulat

2017
Ovarian stimulation in infertile women treated with the use of intrauterine insemination: a cohort study from China.
    Fertility and sterility, 2018, Volume: 109, Issue:5

    Topics: Adult; China; Cohort Studies; Female; Humans; Infertility, Female; Insemination, Artificial; Letrozo

2018
Comparison of the pregnancy outcomes and the incidence of fetal congenital abnormalities in infertile women treated with letrozole and clomiphene citrate.
    The journal of obstetrics and gynaecology research, 2018, Volume: 44, Issue:6

    Topics: Abnormalities, Drug-Induced; Adult; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fema

2018
A Retrospective Study of Letrozole Treatment Prior to Human Chorionic Gonadotropin in Women with Polycystic Ovary Syndrome Undergoing In Vitro Fertilization at Risk of Ovarian Hyperstimulation Syndrome.
    Medical science monitor : international medical journal of experimental and clinical research, 2018, Jun-20, Volume: 24

    Topics: Adult; China; Chorionic Gonadotropin; Embryo Transfer; Female; Fertilization in Vitro; Humans; Infer

2018
Association among depression, symptom experience, and quality of life in polycystic ovary syndrome.
    American journal of obstetrics and gynecology, 2018, Volume: 219, Issue:3

    Topics: Adult; Aromatase Inhibitors; Case-Control Studies; Clomiphene; Depression; Female; Fertility Agents,

2018
Mild ovarian stimulation with letrozole plus fixed dose human menopausal gonadotropin prior to IVF/ICSI for infertile non-obese women with polycystic ovarian syndrome being pre-treated with metformin: a pilot study.
    Reproductive biology and endocrinology : RB&E, 2018, Sep-14, Volume: 16, Issue:1

    Topics: Adult; Female; Gonadotropins; Humans; Infertility, Female; Letrozole; Metformin; Nitriles; Oocyte Re

2018
Luteal support with vaginal dydrogesterone increases pregnancy rate in patients with clomifene resistant polycystic ovary syndrome receiving letrozole for ovulation induction.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2019, Volume: 35, Issue:3

    Topics: Administration, Intravaginal; Adult; Clomiphene; Dydrogesterone; Female; Fertility Agents, Female; H

2019
Comparison of congenital malformations among babies born after administration of letrozole or clomiphene citrate for infertility treatment in a Korean cohort.
    Reproductive toxicology (Elmsford, N.Y.), 2018, Volume: 82

    Topics: Adult; Aromatase Inhibitors; Asian People; Clomiphene; Cohort Studies; Congenital Abnormalities; Fem

2018
Ovulation induction and intrauterine insemination in infertile women with polycystic ovary syndrome: A comparison of drugs.
    European journal of obstetrics, gynecology, and reproductive biology, 2018, Volume: 231

    Topics: Adult; Birth Rate; Clomiphene; Female; Fertility Agents, Female; Humans; Infertility, Female; Insemi

2018
Letrozole for patients with polycystic ovary syndrome: A retrospective study.
    Medicine, 2018, Volume: 97, Issue:44

    Topics: Adult; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Female; Humans; Infertility, Fema

2018
Comparision of Letrozole with Timed Intercourse Versus Clomiphene Citrate with Intrauterine Insemination in Patients with Unexplained Infertility.
    The Journal of reproductive medicine, 2016, Volume: 61, Issue:9-10

    Topics: Adult; Clomiphene; Coitus; Endometrium; Female; Fertility Agents, Female; Humans; Infertility, Femal

2016
Translation and implementation of the Australian-led PCOS guideline: clinical summary and translation resources from the International Evidence-based Guideline for the Assessment and Management of Polycystic Ovary Syndrome.
    The Medical journal of Australia, 2018, 10-01, Volume: 209, Issue:S7

    Topics: Adolescent; Adult; Clomiphene; Disease Management; Evidence-Based Medicine; Female; Humans; Infertil

2018
Letrozole use during frozen embryo transfer cycles in women with polycystic ovary syndrome.
    Fertility and sterility, 2019, Volume: 112, Issue:2

    Topics: Adult; Blastocyst; Cryopreservation; Embryo Transfer; Female; Fertilization in Vitro; Freezing; Horm

2019
Effect of GnRH agonist and letrozole treatment in women with recurrent implantation failure.
    Fertility and sterility, 2019, Volume: 112, Issue:1

    Topics: Adult; Aromatase Inhibitors; Drug Therapy, Combination; Embryo Implantation; Embryo Transfer; Female

2019
Predictive factors for pregnancy during the first four intrauterine insemination cycles using gonadotropin.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2013, Volume: 29, Issue:9

    Topics: Adult; Clomiphene; Female; Fertility Agents, Female; Gonadotropins; Humans; Infertility, Female; Ins

2013
Safety and feasibility of performing two consecutive ovarian stimulation cycles with the use of letrozole-gonadotropin protocol for fertility preservation in breast cancer patients.
    Fertility and sterility, 2013, Volume: 100, Issue:6

    Topics: Adult; Breast Neoplasms; Cohort Studies; Comorbidity; Drug Therapy, Combination; Drug-Related Side E

2013
An assessment of current clinical attitudes toward letrozole use in reproductive endocrinology practices.
    Fertility and sterility, 2013, Volume: 100, Issue:6

    Topics: Aromatase Inhibitors; Attitude of Health Personnel; Attitude to Health; Comorbidity; Drug-Related Si

2013
Endometrial receptivity markers in infertile women stimulated with letrozole compared with clomiphene citrate and natural cycles.
    Systems biology in reproductive medicine, 2014, Volume: 60, Issue:2

    Topics: Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Female; Humans; Infertility, Female; Inf

2014
[Luteal letrozole administration decreases serum estrogen level but not the risk of ovarian hyperstimulation syndrome].
    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2013, Dec-18, Volume: 45, Issue:6

    Topics: Adult; Aromatase Inhibitors; Embryo Transfer; Estrogens; Female; Fertilization in Vitro; Humans; Inf

2013
aP2-Cre-mediated inactivation of estrogen receptor alpha causes hydrometra.
    PloS one, 2014, Volume: 9, Issue:1

    Topics: Animals; Estradiol; Estrogen Receptor alpha; Estrous Cycle; Fatty Acid-Binding Proteins; Female; Gen

2014
The comparision of effect of microdose GnRH-a flare-up, GnRH antagonist/aromatase inhibitor letrozole and GnRH antagonist/clomiphene citrate protocols on IVF outcomes in poor responder patients.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2014, Volume: 30, Issue:7

    Topics: Adult; Aromatase Inhibitors; Clomiphene; Estradiol; Female; Gonadotropin-Releasing Hormone; Humans;

2014
Reproductive endocrinology: revisiting ovulation induction in PCOS.
    Nature reviews. Endocrinology, 2014, Volume: 10, Issue:12

    Topics: Anovulation; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Female; Humans; Infertility

2014
Congenital malformations among babies born following letrozole or clomiphene for infertility treatment.
    PloS one, 2014, Volume: 9, Issue:10

    Topics: Birth Weight; Child; Child, Preschool; Clomiphene; Congenital Abnormalities; Female; Fertility Agent

2014
First reported case of sextuplets conceived via letrozole for ovulation induction.
    Fertility and sterility, 2015, Volume: 103, Issue:2

    Topics: Adult; Aromatase Inhibitors; Female; Humans; Infertility, Female; Letrozole; Multiple Birth Offsprin

2015
Minimal stimulation using gonadotropin combined with clomiphene citrate or letrozole for intrauterine insemination.
    Yonsei medical journal, 2015, Volume: 56, Issue:2

    Topics: Adult; Aromatase Inhibitors; Clomiphene; Drug Administration Schedule; Drug Combinations; Female; Fe

2015
In defense of publishing baseline data from clinical trials.
    Fertility and sterility, 2015, Volume: 103, Issue:4

    Topics: Clomiphene; Female; Fertility Agents, Female; Gonadotropins; Humans; Infertility, Female; Letrozole;

2015
Efficacy of random-start controlled ovarian stimulation in cancer patients.
    Journal of Korean medical science, 2015, Volume: 30, Issue:3

    Topics: Cryopreservation; Estradiol; Female; Fertility Preservation; Fertilization in Vitro; Humans; Inferti

2015
Fertility Preservation Success Subsequent to Concurrent Aromatase Inhibitor Treatment and Ovarian Stimulation in Women With Breast Cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Aug-01, Volume: 33, Issue:22

    Topics: Adult; Aromatase Inhibitors; Breast Neoplasms; Cryopreservation; Embryo, Mammalian; Female; Fertilit

2015
Fertility Preservation Success Subsequent to Concurrent Aromatase Inhibitor Treatment and Ovarian Stimulation in Women With Breast Cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Aug-01, Volume: 33, Issue:22

    Topics: Adult; Aromatase Inhibitors; Breast Neoplasms; Cryopreservation; Embryo, Mammalian; Female; Fertilit

2015
Fertility Preservation Success Subsequent to Concurrent Aromatase Inhibitor Treatment and Ovarian Stimulation in Women With Breast Cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Aug-01, Volume: 33, Issue:22

    Topics: Adult; Aromatase Inhibitors; Breast Neoplasms; Cryopreservation; Embryo, Mammalian; Female; Fertilit

2015
Fertility Preservation Success Subsequent to Concurrent Aromatase Inhibitor Treatment and Ovarian Stimulation in Women With Breast Cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Aug-01, Volume: 33, Issue:22

    Topics: Adult; Aromatase Inhibitors; Breast Neoplasms; Cryopreservation; Embryo, Mammalian; Female; Fertilit

2015
Progesterone levels in letrozole associated controlled ovarian stimulation for fertility preservation in breast cancer patients.
    Human reproduction (Oxford, England), 2015, Volume: 30, Issue:9

    Topics: Adult; Aromatase Inhibitors; Breast Neoplasms; Estradiol; Female; Fertility Preservation; Fertilizat

2015
A comparison of endometrial thickness following augmentation of ovulation with clomifene citrate or letrozole in women with ovulatory infertility.
    The Ceylon medical journal, 2015, Volume: 60, Issue:2

    Topics: Adult; Clomiphene; Endometrium; Female; Fertility Agents, Female; Follicle Stimulating Hormone; Huma

2015
Comparison of Success of Clomiphene citrate and Letrozole in Ovulation Induction.
    Mymensingh medical journal : MMJ, 2016, Volume: 25, Issue:1

    Topics: Adult; Bangladesh; Clomiphene; Female; Fertility Agents, Female; Humans; Infertility, Female; Letroz

2016
Twin delivery after IVF-ET with variable dose letrozole-FSH protocol of lower estradiol in a patient previously treated for breast cancer: a case report.
    European journal of gynaecological oncology, 2016, Volume: 37, Issue:2

    Topics: Adenocarcinoma, Mucinous; Adult; Aromatase Inhibitors; Breast Neoplasms; Embryo Transfer; Estradiol;

2016
Diagnosis and Treatment of Polycystic Ovary Syndrome.
    American family physician, 2016, Jul-15, Volume: 94, Issue:2

    Topics: Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Female; Humans; Hyperandrogenism; Hypogl

2016
GnRH antagonist and letrozole co-treatment in diminished ovarian reserve patients: a proof-of-concept study.
    Reproductive biology, 2017, Volume: 17, Issue:1

    Topics: Adult; Aromatase Inhibitors; Drug Therapy, Combination; Estradiol; Female; Fertility Agents, Female;

2017
Fertility preservation: a vital survivorship issue for young women with breast cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Jun-01, Volume: 26, Issue:16

    Topics: Adult; Breast Neoplasms; Chemotherapy, Adjuvant; Enzyme Inhibitors; Female; Follicle Stimulating Hor

2008
[Effect of two different doses of letrozole in promoting ovulation in infertile women with polycystic ovarian syndrome].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2008, Volume: 28, Issue:11

    Topics: Adult; Aromatase Inhibitors; Female; Fertility Agents, Female; Humans; Infertility, Female; Insemina

2008
[Clinical analysis of assistant treatment proposals for infertile women with polycystic ovary syndrome].
    Zhonghua fu chan ke za zhi, 2008, Volume: 43, Issue:8

    Topics: Adult; Clomiphene; Embryo Transfer; Female; Fertilization in Vitro; Humans; Infertility, Female; Let

2008
Luteal support with intravaginal progesterone increases clinical pregnancy rates in women with polycystic ovary syndrome using letrozole for ovulation induction.
    Fertility and sterility, 2010, Volume: 94, Issue:2

    Topics: Administration, Intravaginal; Adult; Aromatase Inhibitors; Clomiphene; Female; Humans; Infertility,

2010
Luteal support with intravaginal progesterone increases clinical pregnancy rates in women with polycystic ovary syndrome using letrozole for ovulation induction.
    Fertility and sterility, 2010, Volume: 94, Issue:2

    Topics: Administration, Intravaginal; Adult; Aromatase Inhibitors; Clomiphene; Female; Humans; Infertility,

2010
Luteal support with intravaginal progesterone increases clinical pregnancy rates in women with polycystic ovary syndrome using letrozole for ovulation induction.
    Fertility and sterility, 2010, Volume: 94, Issue:2

    Topics: Administration, Intravaginal; Adult; Aromatase Inhibitors; Clomiphene; Female; Humans; Infertility,

2010
Luteal support with intravaginal progesterone increases clinical pregnancy rates in women with polycystic ovary syndrome using letrozole for ovulation induction.
    Fertility and sterility, 2010, Volume: 94, Issue:2

    Topics: Administration, Intravaginal; Adult; Aromatase Inhibitors; Clomiphene; Female; Humans; Infertility,

2010
Random-start controlled ovarian hyperstimulation for emergency fertility preservation in letrozole cycles.
    Fertility and sterility, 2011, Volume: 95, Issue:6

    Topics: Adult; Aromatase Inhibitors; Breast Neoplasms; Carcinoma; Cryopreservation; Drug Administration Sche

2011
Random-start controlled ovarian hyperstimulation for emergency fertility preservation in letrozole cycles.
    Fertility and sterility, 2011, Volume: 95, Issue:6

    Topics: Adult; Aromatase Inhibitors; Breast Neoplasms; Carcinoma; Cryopreservation; Drug Administration Sche

2011
Random-start controlled ovarian hyperstimulation for emergency fertility preservation in letrozole cycles.
    Fertility and sterility, 2011, Volume: 95, Issue:6

    Topics: Adult; Aromatase Inhibitors; Breast Neoplasms; Carcinoma; Cryopreservation; Drug Administration Sche

2011
Random-start controlled ovarian hyperstimulation for emergency fertility preservation in letrozole cycles.
    Fertility and sterility, 2011, Volume: 95, Issue:6

    Topics: Adult; Aromatase Inhibitors; Breast Neoplasms; Carcinoma; Cryopreservation; Drug Administration Sche

2011
Letrozole or clomiphene citrate as first line for anovulatory infertility: a debate.
    Reproductive biology and endocrinology : RB&E, 2011, Jun-21, Volume: 9

    Topics: Anovulation; Aromatase Inhibitors; Clomiphene; Drug Resistance; Female; Fertility Agents, Female; Hu

2011
Letrozole or clomiphene citrate as first line for anovulatory infertility: a debate.
    Reproductive biology and endocrinology : RB&E, 2011, Jun-21, Volume: 9

    Topics: Anovulation; Aromatase Inhibitors; Clomiphene; Drug Resistance; Female; Fertility Agents, Female; Hu

2011
Letrozole or clomiphene citrate as first line for anovulatory infertility: a debate.
    Reproductive biology and endocrinology : RB&E, 2011, Jun-21, Volume: 9

    Topics: Anovulation; Aromatase Inhibitors; Clomiphene; Drug Resistance; Female; Fertility Agents, Female; Hu

2011
Letrozole or clomiphene citrate as first line for anovulatory infertility: a debate.
    Reproductive biology and endocrinology : RB&E, 2011, Jun-21, Volume: 9

    Topics: Anovulation; Aromatase Inhibitors; Clomiphene; Drug Resistance; Female; Fertility Agents, Female; Hu

2011
Body mass index-associated differences in response to ovulation induction with letrozole.
    Fertility and sterility, 2011, Volume: 96, Issue:5

    Topics: Adult; Alabama; Aromatase Inhibitors; Body Mass Index; Chi-Square Distribution; Female; Fertility Ag

2011
Use of the aromatase inhibitor letrozole for ovulation induction in women with polycystic ovarian syndrome.
    Clinical obstetrics and gynecology, 2011, Volume: 54, Issue:4

    Topics: Anovulation; Aromatase Inhibitors; Clomiphene; Congenital Abnormalities; Female; Fertility Agents, F

2011
Drugs for ovulation induction.
    The Medical letter on drugs and therapeutics, 2011, Oct-31, Volume: 53, Issue:1376

    Topics: Clomiphene; Female; Fertility Agents, Female; Humans; Infertility, Female; Insemination, Artificial;

2011
Controlled ovarian hyperstimulation in women with polycystic ovarian syndrome with or without intrauterine insemination.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2012, Volume: 28, Issue:7

    Topics: Adult; Aromatase Inhibitors; Clomiphene; Cohort Studies; Female; Fertility Agents, Female; Gonadotro

2012
Endometrial receptivity defects during IVF cycles with and without letrozole.
    Human reproduction (Oxford, England), 2012, Volume: 27, Issue:3

    Topics: Adult; Aromatase Inhibitors; Birth Rate; Embryo Implantation; Endometrium; Female; Fertilization in

2012
Aromatase inhibition reduces gonadotrophin dose required for controlled ovarian stimulation in women with unexplained infertility.
    Human reproduction (Oxford, England), 2003, Volume: 18, Issue:8

    Topics: Adult; Aromatase Inhibitors; Clomiphene; Enzyme Inhibitors; Estradiol; Female; Fertility Agents, Fem

2003
Doctors in India prescribe unapproved fertility drug.
    BMJ (Clinical research ed.), 2003, Oct-04, Volume: 327, Issue:7418

    Topics: Drug Approval; Drug Labeling; Female; Fertility Agents, Female; Humans; India; Infertility, Female;

2003
Indian firm caught marketing anticancer drug for fertility.
    Lancet (London, England), 2003, Oct-04, Volume: 362, Issue:9390

    Topics: Antineoplastic Agents; Aromatase Inhibitors; Drug Approval; Drug Industry; Enzyme Inhibitors; Female

2003
Indian drug firm accused of illegal marketing of letrozole.
    The Lancet. Oncology, 2003, Volume: 4, Issue:11

    Topics: Drug Approval; Female; Fertility Agents, Female; Humans; India; Infertility, Female; Legislation, Dr

2003
Hormonal profile and endometrial morphology in letrozole-controlled ovarian hyperstimulation in ovulatory infertile patients.
    Fertility and sterility, 2005, Volume: 83, Issue:1

    Topics: Adult; Aromatase Inhibitors; Endometrium; Estradiol; Female; Humans; Infertility, Female; Letrozole;

2005
Letrozole induction of ovulation in women with clomiphene citrate-resistant polycystic ovary syndrome may not depend on the period of infertility, the body mass index, or the luteinizing hormone/follicle-stimulating hormone ratio.
    Fertility and sterility, 2006, Volume: 85, Issue:2

    Topics: Adult; Aromatase Inhibitors; Body Mass Index; Clomiphene; Drug Resistance; Female; Fertility Agents,

2006
Congenital malformations among 911 newborns conceived after infertility treatment with letrozole or clomiphene citrate.
    Fertility and sterility, 2006, Volume: 85, Issue:6

    Topics: Adult; Aromatase Inhibitors; Canada; Clomiphene; Comorbidity; Congenital Abnormalities; Female; Fert

2006
Limiting access to letrozole--is it justified?
    Fertility and sterility, 2007, Volume: 88, Issue:4

    Topics: Aromatase Inhibitors; Female; Heart Defects, Congenital; Humans; Infant, Newborn; Infertility, Femal

2007
[The role of the ovarian steroid aromatase in pathogenesis of reproductive cycles disorders].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2007, Volume: 53, Issue:1

    Topics: Administration, Oral; Anestrus; Animals; Aromatase; Aromatase Inhibitors; Body Weight; Estrous Cycle

2007
In vitro maturation of germinal vesicle oocytes recovered after premature luteinizing hormone surge: description of a novel approach to fertility preservation.
    Fertility and sterility, 2008, Volume: 89, Issue:1

    Topics: Adult; Antineoplastic Agents; Breast Neoplasms; Cell Culture Techniques; Cryopreservation; Drug Admi

2008
Clomiphene citrate: an old favourite lives on.
    Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC, 2007, Volume: 29, Issue:8

    Topics: Anovulation; Clomiphene; Female; Fertility Agents, Female; Humans; Infertility, Female; Letrozole; N

2007
Role of aromatase inhibitor in patients with poor response to clomiphene citrate needs further evaluation.
    The journal of obstetrics and gynaecology research, 2007, Volume: 33, Issue:5

    Topics: Aromatase Inhibitors; Clomiphene; Female; Humans; Infertility, Female; Letrozole; Nitriles; Ovulatio

2007
Controlling for the EFFECTS related to the underlying pathology of infertility.
    Fertility and sterility, 2008, Volume: 89, Issue:5

    Topics: Aromatase Inhibitors; Brain; Clomiphene; Estrogen Antagonists; Estrogens; Female; Humans; Infertilit

2008
Letrozole co-treatment in infertile women 40 years old and older receiving controlled ovarian stimulation and intrauterine insemination.
    Fertility and sterility, 2009, Volume: 91, Issue:6

    Topics: Adult; Aromatase Inhibitors; Case-Control Studies; Drug Therapy, Combination; Endometriosis; Female;

2009