Page last updated: 2024-10-30

letrozole and Hyperplasia

letrozole has been researched along with Hyperplasia in 4 studies

Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.

Research Excerpts

ExcerptRelevanceReference
"Use of a breast cancer cell line (MCF-7) provided biologic confirmation of the role of aromatization in cell proliferation."1.30Macrophages, estrogen and the microenvironment of breast cancer. ( Berstein, LM; Diano, S; Eliza, M; Gutierrez, L; Harada, N; Lysiak, J; Mor, G; Naftolin, F; Santen, RJ; Wang, J; Yue, W, 1998)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Luthra, R1
Kirma, N3
Jones, J1
Tekmal, RR3
Mor, G1
Yue, W1
Santen, RJ1
Gutierrez, L1
Eliza, M1
Berstein, LM1
Harada, N1
Wang, J1
Lysiak, J1
Diano, S1
Naftolin, F1
Gill, K1
Fowler, K1
Mandava, U1

Other Studies

4 other studies available for letrozole and Hyperplasia

ArticleYear
Use of letrozole as a chemopreventive agent in aromatase overexpressing transgenic mice.
    The Journal of steroid biochemistry and molecular biology, 2003, Volume: 86, Issue:3-5

    Topics: Animals; Anticarcinogenic Agents; Aromatase; Aromatase Inhibitors; Birth Weight; Female; Hyperplasia

2003
Macrophages, estrogen and the microenvironment of breast cancer.
    The Journal of steroid biochemistry and molecular biology, 1998, Volume: 67, Issue:5-6

    Topics: Antineoplastic Agents; Aromatase; Breast; Breast Neoplasms; Carcinoma in Situ; Cell Division; Cell L

1998
Aromatase overexpression and breast hyperplasia, an in vivo model--continued overexpression of aromatase is sufficient to maintain hyperplasia without circulating estrogens, and aromatase inhibitors abrogate these preneoplastic changes in mammary glands.
    Endocrine-related cancer, 1999, Volume: 6, Issue:2

    Topics: Animals; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors

1999
Aromatase overexpression transgenic mice model: cell type specific expression and use of letrozole to abrogate mammary hyperplasia without affecting normal physiology.
    The Journal of steroid biochemistry and molecular biology, 2001, Volume: 79, Issue:1-5

    Topics: Animals; Aromatase; Aromatase Inhibitors; Enzyme Inhibitors; Epithelial Cells; Estradiol; Estrogens;

2001