Page last updated: 2024-10-30

letrozole and Genetic Predisposition

letrozole has been researched along with Genetic Predisposition in 3 studies

Research Excerpts

ExcerptRelevanceReference
"Women with previous unilateral breast cancer or prior prophylactic oophorectomy are more likely to enter a medical prevention trial."6.77Uptake of a randomized breast cancer prevention trial comparing letrozole to placebo in BRCA1/2 mutations carriers: the LIBER trial. ( Baudry, K; Berthet, P; Bignon, YJ; Chabbert-Buffet, N; Chiesa, J; Clough, KB; Delaloge, S; Delnatte, C; Dreyfus, H; Dugast, C; Fricker, JP; Gesta, P; Gladieff, L; Lasset, C; Lemonnier, J; Lesur, A; Lortholary, A; Martin, AL; Mijonnet, S; Nogues, C; Prieur, F; Pujol, P; Roca, L; Tennevet, I; This, P; Vennin, P, 2012)
"Women with previous unilateral breast cancer or prior prophylactic oophorectomy are more likely to enter a medical prevention trial."2.77Uptake of a randomized breast cancer prevention trial comparing letrozole to placebo in BRCA1/2 mutations carriers: the LIBER trial. ( Baudry, K; Berthet, P; Bignon, YJ; Chabbert-Buffet, N; Chiesa, J; Clough, KB; Delaloge, S; Delnatte, C; Dreyfus, H; Dugast, C; Fricker, JP; Gesta, P; Gladieff, L; Lasset, C; Lemonnier, J; Lesur, A; Lortholary, A; Martin, AL; Mijonnet, S; Nogues, C; Prieur, F; Pujol, P; Roca, L; Tennevet, I; This, P; Vennin, P, 2012)
"Melasma is an acquired disorder of pigmentation that presents with asymptomatic symmetric darkening of the face."1.46Melasma treatment: A novel approach using a topical agent that contains an anti-estrogen and a vascular endothelial growth factor inhibitor. ( Cohen, PR, 2017)
"Neoadjuvant therapy in breast cancer has emerged as an important setting for the development of targeted drugs."1.37Neoadjuvant chemotherapy and targeted therapies: a promising strategy. ( de Azambuja, E; Metzger-Filho, O, 2011)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cohen, PR1
Metzger-Filho, O1
de Azambuja, E1
Pujol, P1
Lasset, C1
Berthet, P1
Dugast, C1
Delaloge, S1
Fricker, JP1
Tennevet, I1
Chabbert-Buffet, N1
This, P1
Baudry, K1
Lemonnier, J1
Roca, L1
Mijonnet, S1
Gesta, P1
Chiesa, J1
Dreyfus, H1
Vennin, P1
Delnatte, C1
Bignon, YJ1
Lortholary, A1
Prieur, F1
Gladieff, L1
Lesur, A1
Clough, KB1
Nogues, C1
Martin, AL1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prevention of Breast Cancer by Letrozole in Post-menopausal Women Carrying a BRCA1/BRCA2 Mutation[NCT00673335]Phase 3170 participants (Actual)Interventional2008-05-31Active, not recruiting
Genetic Predisposition to Breast and Ovarian Cancer: Prospective Study of BRCAx Gene Mutation[NCT03667417]5,000 participants (Anticipated)Observational1999-10-15Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for letrozole and Genetic Predisposition

ArticleYear
Uptake of a randomized breast cancer prevention trial comparing letrozole to placebo in BRCA1/2 mutations carriers: the LIBER trial.
    Familial cancer, 2012, Volume: 11, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; BRCA1 Protein; BRCA2 Protein; Breast Neoplasms; Double-Blind Met

2012
Uptake of a randomized breast cancer prevention trial comparing letrozole to placebo in BRCA1/2 mutations carriers: the LIBER trial.
    Familial cancer, 2012, Volume: 11, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; BRCA1 Protein; BRCA2 Protein; Breast Neoplasms; Double-Blind Met

2012
Uptake of a randomized breast cancer prevention trial comparing letrozole to placebo in BRCA1/2 mutations carriers: the LIBER trial.
    Familial cancer, 2012, Volume: 11, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; BRCA1 Protein; BRCA2 Protein; Breast Neoplasms; Double-Blind Met

2012
Uptake of a randomized breast cancer prevention trial comparing letrozole to placebo in BRCA1/2 mutations carriers: the LIBER trial.
    Familial cancer, 2012, Volume: 11, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; BRCA1 Protein; BRCA2 Protein; Breast Neoplasms; Double-Blind Met

2012

Other Studies

2 other studies available for letrozole and Genetic Predisposition

ArticleYear
Melasma treatment: A novel approach using a topical agent that contains an anti-estrogen and a vascular endothelial growth factor inhibitor.
    Medical hypotheses, 2017, Volume: 101

    Topics: Administration, Topical; Anastrozole; Androstadienes; Aromatase Inhibitors; Estrogens; Female; Genet

2017
Neoadjuvant chemotherapy and targeted therapies: a promising strategy.
    Journal of the National Cancer Institute. Monographs, 2011, Volume: 2011, Issue:43

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor

2011