Page last updated: 2024-10-30

letrozole and Fibrous Dysplasia, Polyostotic

letrozole has been researched along with Fibrous Dysplasia, Polyostotic in 7 studies

Fibrous Dysplasia, Polyostotic: FIBROUS DYSPLASIA OF BONE affecting several bones. When melanotic pigmentation (CAFE-AU-LAIT SPOTS) and multiple endocrine hyperfunction are additionally associated it is referred to as Albright syndrome.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the efficacy and safety of the third-generation aromatase inhibitor letrozole in the treatment of McCune-Albright syndrome (MAS) girls with peripheral precocious puberty."7.96[Efficacy and safety of letrozole in treatment of McCune-Albright syndrome girls with peripheral precocious puberty]. ( Dong, Z; Lu, W; Wang, J; Wang, W; Wang, X; Xie, Y, 2020)
"Girls with McCune-Albright syndrome (MAS) and related disorders have gonadotropin-independent precocious puberty due to estrogen secretion from ovarian cysts."6.73Letrozole treatment of precocious puberty in girls with the McCune-Albright syndrome: a pilot study. ( Calis, K; Collins, MT; Feuillan, P; Hill, S; Robey, PG; Shawker, T, 2007)
"Letrozole treatment was highly effective at decreasing the rate of skeletal maturation, with a decline in change in bone age over change in chronological age (ΔBA/ΔCA) from 1."5.43Long-term outcomes of letrozole treatment for precocious puberty in girls with McCune-Albright syndrome. ( Boyce, AM; Brillante, BA; Collins, MT; Estrada, A; Gafni, RI; Guthrie, LC, 2016)
"To evaluate the efficacy and safety of the third-generation aromatase inhibitor letrozole in the treatment of McCune-Albright syndrome (MAS) girls with peripheral precocious puberty."3.96[Efficacy and safety of letrozole in treatment of McCune-Albright syndrome girls with peripheral precocious puberty]. ( Dong, Z; Lu, W; Wang, J; Wang, W; Wang, X; Xie, Y, 2020)
"Girls with McCune-Albright syndrome (MAS) and related disorders have gonadotropin-independent precocious puberty due to estrogen secretion from ovarian cysts."2.73Letrozole treatment of precocious puberty in girls with the McCune-Albright syndrome: a pilot study. ( Calis, K; Collins, MT; Feuillan, P; Hill, S; Robey, PG; Shawker, T, 2007)
"McCune-Albright syndrome (MAS) is a rare disease defined by the triad of fibrous dysplasia (FD), café au lait spots, and peripheral precocious puberty (PP)."1.43Clinical and endocrine characteristics and genetic analysis of Korean children with McCune-Albright syndrome: a retrospective cohort study. ( Cho, EK; Cho, SY; Jin, DK; Ki, CS; Kim, J; Lee, JE; Yang, A, 2016)
"Letrozole treatment was highly effective at decreasing the rate of skeletal maturation, with a decline in change in bone age over change in chronological age (ΔBA/ΔCA) from 1."1.43Long-term outcomes of letrozole treatment for precocious puberty in girls with McCune-Albright syndrome. ( Boyce, AM; Brillante, BA; Collins, MT; Estrada, A; Gafni, RI; Guthrie, LC, 2016)
"McCune-Albright syndrome is a rare syndrome, classically defined as the triad of precocious puberty, fibrous dysplasia of bone, and café au lait lesions."1.38Diagnosis and management of precocious puberty in atypical presentations of McCune-Albright syndrome: a case series review. ( Bercaw-Pratt, JL; Dietrich, JE; Karaviti, L; Moorjani, TP; Santos, XM, 2012)
"McCune-Albright syndrome (MAS) is a triad of gonadotropin-independent precocious puberty (GIPP), café-au-lait spots (CALS) and fibrous dysplasia (FD) of bone."1.36McCune-Albright syndrome (MAS): early and extensive bone fibrous dysplasia involvement and "mistaken identity" oophorectomy. ( Gucev, Z; Jancevska, A; Krstevska-Konstantinova, M; Pop-Jordanova, N; Tasic, V, 2010)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's5 (71.43)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Lu, W1
Wang, X1
Wang, J1
Xie, Y1
Dong, Z1
Wang, W1
Neyman, A1
Eugster, EA1
Cho, EK1
Kim, J1
Yang, A1
Ki, CS1
Lee, JE1
Cho, SY1
Jin, DK1
Estrada, A1
Boyce, AM1
Brillante, BA1
Guthrie, LC1
Gafni, RI1
Collins, MT2
Gucev, Z1
Tasic, V1
Jancevska, A1
Krstevska-Konstantinova, M1
Pop-Jordanova, N1
Bercaw-Pratt, JL1
Moorjani, TP1
Santos, XM1
Karaviti, L1
Dietrich, JE1
Feuillan, P1
Calis, K1
Hill, S1
Shawker, T1
Robey, PG1

Trials

1 trial available for letrozole and Fibrous Dysplasia, Polyostotic

ArticleYear
Letrozole treatment of precocious puberty in girls with the McCune-Albright syndrome: a pilot study.
    The Journal of clinical endocrinology and metabolism, 2007, Volume: 92, Issue:6

    Topics: Antineoplastic Agents; Biomarkers; Bone and Bones; Child; Child, Preschool; Female; Fibrous Dysplasi

2007

Other Studies

6 other studies available for letrozole and Fibrous Dysplasia, Polyostotic

ArticleYear
[Efficacy and safety of letrozole in treatment of McCune-Albright syndrome girls with peripheral precocious puberty].
    Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2020, 05-25, Volume: 49, Issue:3

    Topics: Aromatase Inhibitors; Child; China; Female; Fibrous Dysplasia, Polyostotic; Humans; Letrozole; Puber

2020
Treatment of Girls and Boys with McCune-Albright Syndrome with Precocious Puberty - Update 2017.
    Pediatric endocrinology reviews : PER, 2017, Volume: 15, Issue:2

    Topics: Aromatase Inhibitors; Female; Fibrous Dysplasia, Polyostotic; Humans; Letrozole; Male; Puberty, Prec

2017
Clinical and endocrine characteristics and genetic analysis of Korean children with McCune-Albright syndrome: a retrospective cohort study.
    Orphanet journal of rare diseases, 2016, 08-09, Volume: 11, Issue:1

    Topics: Acromegaly; Adolescent; Cafe-au-Lait Spots; Child; Child, Preschool; Chromogranins; Female; Fibrous

2016
Long-term outcomes of letrozole treatment for precocious puberty in girls with McCune-Albright syndrome.
    European journal of endocrinology, 2016, Volume: 175, Issue:5

    Topics: Aromatase Inhibitors; Body Height; Child; Child, Preschool; Cohort Studies; Drug Administration Sche

2016
McCune-Albright syndrome (MAS): early and extensive bone fibrous dysplasia involvement and "mistaken identity" oophorectomy.
    Journal of pediatric endocrinology & metabolism : JPEM, 2010, Volume: 23, Issue:8

    Topics: Aromatase Inhibitors; Child, Preschool; Female; Fibrous Dysplasia, Polyostotic; Follicle Stimulating

2010
Diagnosis and management of precocious puberty in atypical presentations of McCune-Albright syndrome: a case series review.
    Journal of pediatric and adolescent gynecology, 2012, Volume: 25, Issue:1

    Topics: Aromatase Inhibitors; Child, Preschool; Diagnosis, Differential; Female; Fibrous Dysplasia, Polyosto

2012