letrozole has been researched along with Fibroid in 12 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here we report a case of lobular breast cancer metastasizing to a leiomyoma in a patient using letrozole." | 7.77 | Lobular carcinoma of the breast metastasizing to leiomyoma in a patient under letrozole treatment. ( Aydinli, K; Basgul, AY; Calay, Z; Dünder, I; Güdücü, N; Işçi, H, 2011) |
| "The objective was to determine the direct effect of letrozole on the proliferation and apoptosis of cultured leiomyoma cells co-treated with prostaglandin E(2) (PGE(2))." | 7.74 | Effects of letrozole on proliferation and apoptosis in cultured leiomyoma cells treated with prostaglandin E(2). ( Han, M; Kim, JM; Kim, JY; Lee, KS; Park, JE, 2008) |
| "Uterine leiomyomas are the most common benign tumours of the female genital tract, often necessitating hysterectomy." | 6.73 | Treatment of symptomatic uterine leiomyoma with letrozole. ( Celik, H; Gurates, B; Kilic, G; Kumru, S; Parmaksiz, C; Simsek, M, 2008) |
| " EPIGALLOCATECHIN GALLATE (EGCG) FOR TREATMENT OF UNEXPLAINED INFERTILITY ASSOCIATED WITH UTERINE FIBROIDS (PRE-FRIEND TRIAL): EARLY SAFETY ASSESSMENT." | 5.69 | Assessing the Hepatic Safety of Epigallocatechin Gallate (EGCG) in Reproductive-Aged Women. ( Al-Hendy, A; Christman, GM; Flaminia, A; Flores, VA; González, F; Huang, H; Johnson, JJ; Segars, J; Siblini, H; Singh, B; Taylor, HS; Zhang, H, 2023) |
| "Condensation letrozole in combination with cabergoline in the management of uterine fibroids." | 5.24 | Comparing the effect of aromatase inhibitor (letrozole) + cabergoline (Dostinex) and letrozole alone on uterine myoma regression,a randomized clinical trial. ( Gharabaghi, PM; Mobasseri, M; Ouladsahebmadarek, E; Rahmani, V; Sayyah-Melli, M, 2017) |
| "This was a preliminary study to determine the effect of aromatase inhibitors in preventing the flare induced by GnRH agonist (GnRH-a) in women with endometriosis (n = 9) or leiomyomata (n = 4) who were given letrozole on the first 5 days of the GnRH-a therapy." | 5.14 | Aromatase inhibitors prevent the estrogen rise associated with the flare effect of gonadotropins in patients treated with GnRH agonists. ( Bedaiwy, MA; Casper, RF; Mousa, NA, 2009) |
| " Here we report a case of lobular breast cancer metastasizing to a leiomyoma in a patient using letrozole." | 3.77 | Lobular carcinoma of the breast metastasizing to leiomyoma in a patient under letrozole treatment. ( Aydinli, K; Basgul, AY; Calay, Z; Dünder, I; Güdücü, N; Işçi, H, 2011) |
| "The objective was to determine the direct effect of letrozole on the proliferation and apoptosis of cultured leiomyoma cells co-treated with prostaglandin E(2) (PGE(2))." | 3.74 | Effects of letrozole on proliferation and apoptosis in cultured leiomyoma cells treated with prostaglandin E(2). ( Han, M; Kim, JM; Kim, JY; Lee, KS; Park, JE, 2008) |
| "The quality of the myometrial scar, defined by ultrasound evaluation, was similar in the two study groups both at one-week (p=0." | 2.79 | Preoperative treatment with letrozole in patients undergoing laparoscopic myomectomy of large uterine myomas: a prospective non-randomized study. ( Ferrero, S; Leone Roberti Maggiore, U; Scala, C; Venturini, PL, 2014) |
| "Uterine leiomyomas are the most common benign tumours of the female genital tract, often necessitating hysterectomy." | 2.73 | Treatment of symptomatic uterine leiomyoma with letrozole. ( Celik, H; Gurates, B; Kilic, G; Kumru, S; Parmaksiz, C; Simsek, M, 2008) |
| "Uterine fibroids, also called uterine leiomyomas or myomas, are the most common benign tumours in women of reproductive age." | 2.49 | Aromatase inhibitors for uterine fibroids. ( Lu, D; Navaratnam, K; Shi, G; Song, H, 2013) |
| "Intra- and postoperative complications, postoperative pain, and patient satisfaction were similar in the four study groups." | 1.42 | Three-month treatment with triptorelin, letrozole and ulipristal acetate before hysteroscopic resection of uterine myomas: prospective comparative pilot study. ( Bizzarri, N; Ferrero, S; Ghirardi, V; Remorgida, V; Venturini, PL, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 8 (66.67) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Siblini, H | 1 |
| Al-Hendy, A | 1 |
| Segars, J | 1 |
| González, F | 1 |
| Taylor, HS | 1 |
| Singh, B | 1 |
| Flaminia, A | 1 |
| Flores, VA | 1 |
| Christman, GM | 1 |
| Huang, H | 1 |
| Johnson, JJ | 1 |
| Zhang, H | 1 |
| Duhan, N | 1 |
| Madaan, S | 1 |
| Sen, J | 1 |
| Song, H | 1 |
| Lu, D | 1 |
| Navaratnam, K | 1 |
| Shi, G | 1 |
| Leone Roberti Maggiore, U | 1 |
| Scala, C | 1 |
| Venturini, PL | 3 |
| Ferrero, S | 3 |
| Bizzarri, N | 1 |
| Ghirardi, V | 1 |
| Remorgida, V | 2 |
| Sayyah-Melli, M | 1 |
| Mobasseri, M | 1 |
| Gharabaghi, PM | 1 |
| Ouladsahebmadarek, E | 1 |
| Rahmani, V | 1 |
| Gurates, B | 1 |
| Parmaksiz, C | 1 |
| Kilic, G | 1 |
| Celik, H | 1 |
| Kumru, S | 1 |
| Simsek, M | 1 |
| Bedaiwy, MA | 1 |
| Mousa, NA | 1 |
| Casper, RF | 1 |
| Parsanezhad, ME | 1 |
| Azmoon, M | 1 |
| Alborzi, S | 1 |
| Rajaeefard, A | 1 |
| Zarei, A | 1 |
| Kazerooni, T | 1 |
| Frank, V | 1 |
| Schmidt, EH | 1 |
| Işçi, H | 1 |
| Güdücü, N | 1 |
| Basgul, AY | 1 |
| Aydinli, K | 1 |
| Calay, Z | 1 |
| Dünder, I | 1 |
| Han, M | 1 |
| Kim, JY | 1 |
| Park, JE | 1 |
| Kim, JM | 1 |
| Lee, KS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Influence of the Aromatase Inhibitor Anastrozole and GnRH Analog Goserelin Acetate as Preoperative Treatment of Vaginal Surgical Treatment of Uterine Leiomyoma: Analysis of Intra and Immediate/Late Postoperative Patterns[NCT01280045] | 5 participants (Actual) | Interventional | 2011-01-31 | Terminated (stopped due to No grant was received then we stopped the recruitment) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for letrozole and Fibroid
| Article | Year |
|---|---|
Aromatase inhibitors for uterine fibroids.
Topics: Antineoplastic Agents; Aromatase Inhibitors; Female; Hot Flashes; Humans; Leiomyoma; Letrozole; Nitr | 2013 |
6 trials available for letrozole and Fibroid
| Article | Year |
|---|---|
Assessing the Hepatic Safety of Epigallocatechin Gallate (EGCG) in Reproductive-Aged Women.
Topics: Adult; Catechin; Clomiphene; Female; Folic Acid; Humans; Infertility; Leiomyoma; Letrozole; Liver; P | 2023 |
Preoperative treatment with letrozole in patients undergoing laparoscopic myomectomy of large uterine myomas: a prospective non-randomized study.
Topics: Adult; Antineoplastic Agents; Blood Loss, Surgical; Chemotherapy, Adjuvant; Cicatrix; Contraceptives | 2014 |
Comparing the effect of aromatase inhibitor (letrozole) + cabergoline (Dostinex) and letrozole alone on uterine myoma regression,a randomized clinical trial.
Topics: Adult; Antineoplastic Agents; Aromatase Inhibitors; Cabergoline; Drug Therapy, Combination; Ergoline | 2017 |
Treatment of symptomatic uterine leiomyoma with letrozole.
Topics: Adult; Antineoplastic Agents; Aromatase Inhibitors; Bone and Bones; Bone Density; Female; Follicle S | 2008 |
Aromatase inhibitors prevent the estrogen rise associated with the flare effect of gonadotropins in patients treated with GnRH agonists.
Topics: Adult; Aromatase Inhibitors; Endometriosis; Estrogens; Female; Follicle Stimulating Hormone; Gonadot | 2009 |
A randomized, controlled clinical trial comparing the effects of aromatase inhibitor (letrozole) and gonadotropin-releasing hormone agonist (triptorelin) on uterine leiomyoma volume and hormonal status.
Topics: Adult; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Estradiol; Female; Follicle Stimulatin | 2010 |
5 other studies available for letrozole and Fibroid
| Article | Year |
|---|---|
Role of the aromatase inhibitor letrozole in the management of uterine leiomyomas in premenopausal women.
Topics: Adult; Aromatase Inhibitors; Female; Humans; Leiomyoma; Letrozole; Middle Aged; Nitriles; Premenopau | 2013 |
Three-month treatment with triptorelin, letrozole and ulipristal acetate before hysteroscopic resection of uterine myomas: prospective comparative pilot study.
Topics: Adult; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Attitude of Health Personnel; Contrace | 2015 |
Letrozole monotherapy in the treatment of uterine myomas.
Topics: Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Fema | 2010 |
Lobular carcinoma of the breast metastasizing to leiomyoma in a patient under letrozole treatment.
Topics: Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Lobular; Female; Humans; Leiomyoma; Letrozole; Mi | 2011 |
Effects of letrozole on proliferation and apoptosis in cultured leiomyoma cells treated with prostaglandin E(2).
Topics: Apoptosis; Aromatase Inhibitors; Cell Proliferation; Cells, Cultured; Dinoprostone; Enzyme Activator | 2008 |