letrozole has been researched along with Delayed Puberty in 21 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " In contrast, in the testosterone-plus-letrozole-treated group, the concentration decreased during letrozole treatment, indicating improved insulin sensitivity." | 5.10 | The role of sex steroids in the regulation of insulin sensitivity and serum lipid concentrations during male puberty: a prospective study with a P450-aromatase inhibitor. ( Dunkel, L; Saukkonen, T; Wickman, S, 2002) |
| "In terms of HRQoL, the main impact of delayed puberty was dissatisfaction with physical appearance." | 3.11 | Health-related quality of life in boys with constitutional delay of growth and puberty. ( Hero, M; Huopio, H; Kariola, L; Kosola, S; Miettinen, PJ; Raivio, T; Sintonen, H; Tenhola, S; Toppari, J; Varimo, T; Voutilainen, R, 2022) |
| "Letrozole was superior to placebo [mean difference (MD) 4." | 2.82 | Efficacy and Safety of Letrozole in the Management of Constitutional Delay in Growth and Puberty: A Systematic Review and Meta-analysis ( Dutta, D; Sharma, M; Singla, R; Surana, V, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 11 (52.38) | 29.6817 |
| 2010's | 5 (23.81) | 24.3611 |
| 2020's | 5 (23.81) | 2.80 |
| Authors | Studies |
|---|---|
| Dutta, D | 1 |
| Singla, R | 1 |
| Surana, V | 1 |
| Sharma, M | 1 |
| Huttunen, H | 1 |
| Varimo, T | 6 |
| Huopio, H | 5 |
| Voutilainen, R | 5 |
| Tenhola, S | 5 |
| Miettinen, PJ | 6 |
| Raivio, T | 7 |
| Hero, M | 9 |
| Kariola, L | 3 |
| Kosola, S | 2 |
| Toppari, J | 4 |
| Sintonen, H | 2 |
| Rohani, F | 1 |
| Asadi, R | 1 |
| Mirboluk, AA | 1 |
| Soheilipour, F | 1 |
| Kohva, E | 1 |
| Vaaralahti, K | 3 |
| Viinamäki, J | 1 |
| Backman, JT | 1 |
| Wang, Y | 1 |
| Dattani, MT | 1 |
| Toiviainen-Salo, S | 2 |
| Hämäläinen, E | 1 |
| Pulkkinen, MA | 1 |
| Lääperi, M | 1 |
| Tarkkanen, A | 1 |
| Wickman, S | 9 |
| Mäkitie, O | 1 |
| Dunkel, L | 9 |
| Salehpour, S | 1 |
| Alipour, P | 1 |
| Razzaghy-Azar, M | 1 |
| Ardeshirpour, L | 1 |
| Shamshiri, A | 1 |
| Monfared, MF | 1 |
| Gharib, A | 1 |
| Jänne, OA | 1 |
| Hanhijärvi, R | 1 |
| Siimes, MA | 1 |
| Stanhope, R | 1 |
| Sipilä, I | 1 |
| Ankarberg-Lindgren, C | 1 |
| Norjavaara, E | 1 |
| Cianfarani, S | 1 |
| Hagenäs, L | 1 |
| Saukkonen, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Constitutional Delay of Growth and Puberty: Towards Evidence-based Treatment[NCT01797718] | Phase 2/Phase 3 | 35 participants (Actual) | Interventional | 2013-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for letrozole and Delayed Puberty
| Article | Year |
|---|---|
Efficacy and Safety of Letrozole in the Management of Constitutional Delay in Growth and Puberty: A Systematic Review and Meta-analysis
Topics: Body Height; Child; Growth Disorders; Humans; Letrozole; Luteinizing Hormone; Puberty; Puberty, Dela | 2022 |
15 trials available for letrozole and Delayed Puberty
| Article | Year |
|---|---|
Serum testosterone and oestradiol predict the growth response during puberty promoting treatment.
Topics: Body Height; Child; Estradiol; Humans; Letrozole; Male; Puberty; Puberty, Delayed; Testosterone | 2022 |
Health-related quality of life in boys with constitutional delay of growth and puberty.
Topics: Adolescent; Child; Humans; Letrozole; Male; Puberty; Puberty, Delayed; Quality of Life; Testosterone | 2022 |
Health-related quality of life in boys with constitutional delay of growth and puberty.
Topics: Adolescent; Child; Humans; Letrozole; Male; Puberty; Puberty, Delayed; Quality of Life; Testosterone | 2022 |
Health-related quality of life in boys with constitutional delay of growth and puberty.
Topics: Adolescent; Child; Humans; Letrozole; Male; Puberty; Puberty, Delayed; Quality of Life; Testosterone | 2022 |
Health-related quality of life in boys with constitutional delay of growth and puberty.
Topics: Adolescent; Child; Humans; Letrozole; Male; Puberty; Puberty, Delayed; Quality of Life; Testosterone | 2022 |
Anti-Müllerian hormone and letrozole levels in boys with constitutional delay of growth and puberty treated with letrozole or testosterone.
Topics: Adolescent; Anti-Mullerian Hormone; Biomarkers; Child; Female; Finland; Growth Disorders; Humans; Hy | 2020 |
Circulating miR-30b levels increase during male puberty.
Topics: Adolescent; Drug Therapy, Combination; Gonads; Growth Disorders; Hormone Replacement Therapy; Humans | 2021 |
Letrozole versus testosterone for promotion of endogenous puberty in boys with constitutional delay of growth and puberty: a randomised controlled phase 3 trial.
Topics: Adolescent; Androgens; Aromatase Inhibitors; Biomarkers; Drug Administration Schedule; Hormones; Hum | 2019 |
Vertebral morphology in aromatase inhibitor-treated males with idiopathic short stature or constitutional delay of puberty.
Topics: Adolescent; Aromatase Inhibitors; Child; Growth Disorders; Humans; Letrozole; Magnetic Resonance Ima | 2010 |
A double-blind, placebo-controlled comparison of letrozole to oxandrolone effects upon growth and puberty of children with constitutional delay of puberty and idiopathic short stature.
Topics: Adolescent; Androgens; Aromatase Inhibitors; Body Height; Bone Density; Cholesterol; Double-Blind Me | 2010 |
Novel treatment of short stature with aromatase inhibitors.
Topics: Adolescent; Aromatase Inhibitors; Body Height; Bone Density; Bone Development; Enzyme Inhibitors; Es | 2003 |
Serum androgen bioactivity in adolescence: a longitudinal study of boys with constitutional delay of puberty.
Topics: Adolescent; Androgens; Drug Therapy, Combination; Enzyme Inhibitors; Humans; Letrozole; Longitudinal | 2004 |
Pubertal upregulation of erythropoiesis in boys is determined primarily by androgen.
Topics: Adolescent; Androgens; Aromatase Inhibitors; Child; Double-Blind Method; Drug Therapy, Combination; | 2005 |
Treatment with the aromatase inhibitor letrozole during adolescence increases near-final height in boys with constitutional delay of puberty.
Topics: Adolescent; Aromatase Inhibitors; Body Height; Estradiol; Follicle Stimulating Hormone; Humans; Letr | 2006 |
A specific aromatase inhibitor and potential increase in adult height in boys with delayed puberty: a randomised controlled trial.
Topics: Adolescent; Aromatase Inhibitors; Body Height; Double-Blind Method; Drug Therapy, Combination; Human | 2001 |
Treatment of delayed male puberty: efficacy of aromatase inhibition.
Topics: Adolescent; Aromatase Inhibitors; Body Height; Bone Density; Bone Development; Double-Blind Method; | 2001 |
The role of sex steroids in the regulation of insulin sensitivity and serum lipid concentrations during male puberty: a prospective study with a P450-aromatase inhibitor.
Topics: Adolescent; Aromatase Inhibitors; Body Composition; Body Height; Body Weight; Double-Blind Method; E | 2002 |
Novel treatment of delayed male puberty with aromatase inhibitors.
Topics: Adolescent; Analysis of Variance; Aromatase Inhibitors; Biomarkers; Body Height; Bone Density; Bone | 2002 |
5 other studies available for letrozole and Delayed Puberty
| Article | Year |
|---|---|
Letrozole Effect on Final Height of Patients with Constitutional Delay of Growth and Puberty.
Topics: Adolescent; Aromatase Inhibitors; Body Height; Case-Control Studies; Follow-Up Studies; Growth Disor | 2019 |
Letrozole: a new treatment for delayed puberty in boys?
Topics: Humans; Letrozole; Male; Puberty, Delayed; Sexual Maturation; Testosterone | 2019 |
Use of a specific aromatase inhibitor in delayed puberty.
Topics: Adolescent; Aromatase Inhibitors; Estradiol; Humans; Letrozole; Male; Nitriles; Puberty, Delayed; Te | 2001 |
Role of hormones in puberty.
Topics: Body Height; Child; Enzyme Inhibitors; Female; Gonadal Steroid Hormones; Growth; Humans; Letrozole; | 2001 |
[Growth rate can be manipulated. Estrogen production in pubertal boys can be blocked by an aromatase inhibitor].
Topics: Age Determination by Skeleton; Aromatase Inhibitors; Body Height; Child; Controlled Clinical Trials | 2002 |