letrozole has been researched along with Cell Transformation, Neoplastic in 2 studies
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Estrogen is a risk factor of breast cancer." | 1.39 | Aromatase overexpression induces malignant changes in estrogen receptor α negative MCF-10A cells. ( Gildea, JJ; Wang, J; Yue, W, 2013) |
| "About two-thirds of human breast carcinomas contain detectable levels of aromatase, the enzyme which converts androgens to oestrogens." | 1.29 | An in vivo model of intratumoural aromatase using aromatase-transfected MCF7 human breast cancer cells. ( Ashworth, A; Detre, S; Dowsett, M; Lee, K; Macaulay, VM; Nicholls, JE, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, J | 1 |
| Gildea, JJ | 1 |
| Yue, W | 1 |
| Lee, K | 1 |
| Macaulay, VM | 1 |
| Nicholls, JE | 1 |
| Detre, S | 1 |
| Ashworth, A | 1 |
| Dowsett, M | 1 |
2 other studies available for letrozole and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Aromatase overexpression induces malignant changes in estrogen receptor α negative MCF-10A cells.
Topics: Androstenedione; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Biomarkers, Tumor | 2013 |
An in vivo model of intratumoural aromatase using aromatase-transfected MCF7 human breast cancer cells.
Topics: Animals; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Cell Division; Ce | 1995 |