letrozole has been researched along with Carcinoma, Intraepithelial in 4 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " Further studies are needed to determine the feasibility of selecting an effective AI dosing schedule with better tolerability." | 6.82 | Double-Blind, Randomized Trial of Alternative Letrozole Dosing Regimens in Postmenopausal Women with Increased Breast Cancer Risk. ( Boughey, JC; Chow, HH; Frank, D; Hsu, CH; Lang, JE; Ley, M; López, AM; Perloff, M; Pruthi, S; Taverna, JA, 2016) |
| "Primary tumor material was retrospectively collected from 88 patients who participated in a randomized clinical trial comparing the AI letrozole to the anti-estrogen tamoxifen for first-line treatment of advanced breast cancer." | 5.14 | In situ aromatase expression in primary tumor is associated with estrogen receptor expression but is not predictive of response to endocrine therapy in advanced breast cancer. ( Ejlertsen, B; Evans, DB; Henriksen, KL; Lykkesfeldt, AE; Mouridsen, HT; Møller, S; Rasmussen, BB; Sasano, H, 2009) |
| " Further studies are needed to determine the feasibility of selecting an effective AI dosing schedule with better tolerability." | 2.82 | Double-Blind, Randomized Trial of Alternative Letrozole Dosing Regimens in Postmenopausal Women with Increased Breast Cancer Risk. ( Boughey, JC; Chow, HH; Frank, D; Hsu, CH; Lang, JE; Ley, M; López, AM; Perloff, M; Pruthi, S; Taverna, JA, 2016) |
| "Use of a breast cancer cell line (MCF-7) provided biologic confirmation of the role of aromatization in cell proliferation." | 1.30 | Macrophages, estrogen and the microenvironment of breast cancer. ( Berstein, LM; Diano, S; Eliza, M; Gutierrez, L; Harada, N; Lysiak, J; Mor, G; Naftolin, F; Santen, RJ; Wang, J; Yue, W, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Youngwirth, LM | 1 |
| Boughey, JC | 2 |
| Hwang, ES | 1 |
| López, AM | 1 |
| Pruthi, S | 1 |
| Perloff, M | 1 |
| Hsu, CH | 1 |
| Lang, JE | 1 |
| Ley, M | 1 |
| Frank, D | 1 |
| Taverna, JA | 1 |
| Chow, HH | 1 |
| Lykkesfeldt, AE | 1 |
| Henriksen, KL | 1 |
| Rasmussen, BB | 1 |
| Sasano, H | 1 |
| Evans, DB | 1 |
| Møller, S | 1 |
| Ejlertsen, B | 1 |
| Mouridsen, HT | 1 |
| Mor, G | 1 |
| Yue, W | 1 |
| Santen, RJ | 1 |
| Gutierrez, L | 1 |
| Eliza, M | 1 |
| Berstein, LM | 1 |
| Harada, N | 1 |
| Wang, J | 1 |
| Lysiak, J | 1 |
| Diano, S | 1 |
| Naftolin, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase I Dose-Finding Trial of Letrozole in Postmenopausal Women at High Risk for Breast Cancer[NCT01077453] | Phase 1 | 112 participants (Actual) | Interventional | 2010-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for letrozole and Carcinoma, Intraepithelial
| Article | Year |
|---|---|
Double-Blind, Randomized Trial of Alternative Letrozole Dosing Regimens in Postmenopausal Women with Increased Breast Cancer Risk.
Topics: Antineoplastic Agents; Breast Neoplasms; Carcinoma in Situ; Carcinoma, Lobular; Double-Blind Method; | 2016 |
In situ aromatase expression in primary tumor is associated with estrogen receptor expression but is not predictive of response to endocrine therapy in advanced breast cancer.
Topics: Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Carcinoma in Sit | 2009 |
2 other studies available for letrozole and Carcinoma, Intraepithelial
| Article | Year |
|---|---|
Surgery versus monitoring and endocrine therapy for low-risk DCIS: The COMET Trial.
Topics: Adult; Aged; Aromatase Inhibitors; Breast Neoplasms; Carcinoma in Situ; Carcinoma, Ductal, Breast; C | 2017 |
Macrophages, estrogen and the microenvironment of breast cancer.
Topics: Antineoplastic Agents; Aromatase; Breast; Breast Neoplasms; Carcinoma in Situ; Cell Division; Cell L | 1998 |