letrozole has been researched along with Carcinogenesis in 3 studies
Carcinogenesis: The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the effects of letrozole (Ltz) in carcinogen+estrogen-induced endometrial hyperplasia." | 7.83 | Effect of letrozole in carcinogen-plus-estrogen-induced endometrial hyperplasia in mice. ( Cândido, EB; Carneiro, MM; Carvalho-Macedo, AC; Lara, AC; Rocha, AL; Silva-Filho, AL; Vidigal, PV, 2016) |
| " To test whether the formation of E2 from T by aromatase could lead to estrogen genotoxicity and prostate carcinogenesis we then rats treated with T and 2F-E2 also with letrozole and found that it reduced prostate cancer incidence by about 50%." | 4.31 | Hormonal and genotoxic estrogen-androgen carcinogenesis in the NBL rat prostate: A role for aromatase. ( Bosland, MC; Horton, L; Schlicht, MJ; Vega, K, 2023) |
| "To evaluate the effects of letrozole (Ltz) in carcinogen+estrogen-induced endometrial hyperplasia." | 3.83 | Effect of letrozole in carcinogen-plus-estrogen-induced endometrial hyperplasia in mice. ( Cândido, EB; Carneiro, MM; Carvalho-Macedo, AC; Lara, AC; Rocha, AL; Silva-Filho, AL; Vidigal, PV, 2016) |
| "The etiology of ovarian epithelial cancer is poorly understood, mainly due to the lack of an appropriate experimental model for studying the onset and progression of this disease." | 1.40 | Dysregulated estrogen receptor signaling in the hypothalamic-pituitary-ovarian axis leads to ovarian epithelial tumorigenesis in mice. ( Bagchi, IC; Bagchi, MK; Haschek, WM; Kannan, A; Laws, MJ; Pawar, S, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Bosland, MC | 1 |
| Vega, K | 1 |
| Horton, L | 1 |
| Schlicht, MJ | 1 |
| Laws, MJ | 1 |
| Kannan, A | 1 |
| Pawar, S | 1 |
| Haschek, WM | 1 |
| Bagchi, MK | 1 |
| Bagchi, IC | 1 |
| Lara, AC | 1 |
| Cândido, EB | 1 |
| Vidigal, PV | 1 |
| Rocha, AL | 1 |
| Carvalho-Macedo, AC | 1 |
| Carneiro, MM | 1 |
| Silva-Filho, AL | 1 |
3 other studies available for letrozole and Carcinogenesis
| Article | Year |
|---|---|
Hormonal and genotoxic estrogen-androgen carcinogenesis in the NBL rat prostate: A role for aromatase.
Topics: Androgens; Animals; Aromatase; Carcinogenesis; DNA Damage; Estradiol; Estrogens; Humans; Letrozole; | 2023 |
Dysregulated estrogen receptor signaling in the hypothalamic-pituitary-ovarian axis leads to ovarian epithelial tumorigenesis in mice.
Topics: Animals; Carcinogenesis; Carcinoma, Ovarian Epithelial; Estrogen Receptor alpha; Estrogens; Female; | 2014 |
Effect of letrozole in carcinogen-plus-estrogen-induced endometrial hyperplasia in mice.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Carcinogenesis; Endo | 2016 |