Page last updated: 2024-10-30

letrozole and Cancer of Prostate

letrozole has been researched along with Cancer of Prostate in 6 studies

Research Excerpts

ExcerptRelevanceReference
" To test whether the formation of E2 from T by aromatase could lead to estrogen genotoxicity and prostate carcinogenesis we then rats treated with T and 2F-E2 also with letrozole and found that it reduced prostate cancer incidence by about 50%."4.31Hormonal and genotoxic estrogen-androgen carcinogenesis in the NBL rat prostate: A role for aromatase. ( Bosland, MC; Horton, L; Schlicht, MJ; Vega, K, 2023)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's3 (50.00)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Thomas, MP1
Potter, BV1
Bosland, MC1
Vega, K1
Horton, L1
Schlicht, MJ1
Martinez Vila, C1
Fernández-Morales, LA1
Oliveres, H1
Marín, M1
Ribera, P1
Pardo, JC1
Dalmau, E1
Segui, MA1
Masoodi, KZ1
Ramos Garcia, R1
Pascal, LE1
Wang, Y1
Ma, HM1
O'Malley, K1
Eisermann, K1
Shevrin, DH1
Nguyen, HM1
Vessella, RL1
Nelson, JB1
Parikh, RA1
Wang, Z1
Smith, MR1
Kaufman, D1
George, D1
Oh, WK1
Kazanis, M1
Manola, J1
Kantoff, PW1
Antognelli, C1
Del Buono, C1
Baldracchini, F1
Talesa, V1
Cottini, E1
Brancadoro, C1
Zucchi, A1
Mearini, E1

Trials

1 trial available for letrozole and Cancer of Prostate

ArticleYear
Selective aromatase inhibition for patients with androgen-independent prostate carcinoma.
    Cancer, 2002, Nov-01, Volume: 95, Issue:9

    Topics: Aged; Aged, 80 and over; Androgens; Antineoplastic Agents; Aromatase Inhibitors; Enzyme Inhibitors;

2002

Other Studies

5 other studies available for letrozole and Cancer of Prostate

ArticleYear
Discovery and Development of the Aryl O-Sulfamate Pharmacophore for Oncology and Women's Health.
    Journal of medicinal chemistry, 2015, Oct-08, Volume: 58, Issue:19

    Topics: Animals; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Drug Discovery; Endometriosi

2015
Hormonal and genotoxic estrogen-androgen carcinogenesis in the NBL rat prostate: A role for aromatase.
    The Prostate, 2023, Volume: 83, Issue:9

    Topics: Androgens; Animals; Aromatase; Carcinogenesis; DNA Damage; Estradiol; Estrogens; Humans; Letrozole;

2023
Fulvestrant plus LHRH analogues in male with synchronous breast and prostate cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2017, 08-01, Volume: 28, Issue:8

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms, Male; Estradiol; Fulvestrant

2017
5α-reductase inhibition suppresses testosterone-induced initial regrowth of regressed xenograft prostate tumors in animal models.
    Endocrinology, 2013, Volume: 154, Issue:7

    Topics: 5-alpha Reductase Inhibitors; Animals; Azasteroids; Cell Line, Tumor; Cell Proliferation; Dutasterid

2013
Alteration of glyoxalase genes expression in response to testosterone in LNCaP and PC3 human prostate cancer cells.
    Cancer biology & therapy, 2007, Volume: 6, Issue:12

    Topics: Adenocarcinoma; Androgens; Aromatase Inhibitors; Base Sequence; Cell Line, Tumor; Enzyme Induction;

2007