letrozole has been researched along with Body Weight in 32 studies
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Interestingly, naringenin supplementation significantly reduced body weight, ameliorated hormone levels, improved insulin resistance, and mitigated pathological changes in ovarian tissue, up-regulated the expression of PGC-1ɑ, SIRT1, occludin and claudin-1 in colon." | 8.12 | Naringenin regulates gut microbiota and SIRT1/ PGC-1ɑ signaling pathway in rats with letrozole-induced polycystic ovary syndrome. ( An, T; Bao, XL; Gao, L; Han, BS; Hu, YY; Jiang, GJ; Lian, J; Lv, BH; Wang, TY; Wu, YX; Yang, XY, 2022) |
| "BACKGROUND The aim of this study was to explore whether letrozole and high-fat diets (HFD) can induce obese insulin-resistant polycystic ovary syndrome (PCOS) with all reproductive and metabolic phenotypes in a rat model." | 7.96 | Letrozole Rat Model Mimics Human Polycystic Ovarian Syndrome and Changes in Insulin Signal Pathways. ( Dun, J; Huang, L; Huang, M; Ji, F; Lin, Q; Lin, Y; Xu, J; Yang, J; You, X; Zhang, J, 2020) |
| " The study investigated the effects of quercetin in a letrozole induced rat model of polycystic ovarian syndrome, which displayed both clinical and metabolic features as in PCOS women." | 7.88 | Therapeutic potentials of Quercetin in management of polycystic ovarian syndrome using Letrozole induced rat model: a histological and a biochemical study. ( Abid, A; Afsar, T; Almajwal, A; Jahan, S; Khalid, S; Razak, S; Shaheen, G, 2018) |
| "Here we hypothesized that exercise in dihydrotestosterone (DHT) or letrozole (LET)-induced polycystic ovary syndrome mouse models improves impaired insulin and glucose metabolism, adipose tissue morphology, and expression of genes related to adipogenesis, lipid metabolism, Notch pathway and browning in inguinal and mesenteric fat." | 7.85 | Exercise differentially affects metabolic functions and white adipose tissue in female letrozole- and dihydrotestosterone-induced mouse models of polycystic ovary syndrome. ( Benrick, A; Carlström, M; Cushman, SW; Fornes, R; Hu, M; Ivarsson, N; Maciel, GAR; Maliqueo, M; Marcondes, RR; Stener-Victorin, E; Stenkula, KG, 2017) |
| " The study was undertaken to investigate the possible protective and ameliorating effects of GABA in Letrozole induced PCOS model in rats by targeting insulin resistance." | 7.85 | Protective effects of GABA against metabolic and reproductive disturbances in letrozole induced polycystic ovarian syndrome in rats. ( Afsar, T; Almajwal, A; Jahan, S; Pirzada, M; Rauf, N; Razak, S; Ullah, A; Ullah, H, 2017) |
| " Polycystic ovary syndrome was induced by letrozole administration, and animals presented with obesity, sex hormone disorder, no ovulation, large cystic follicles, and increasing fasting insulin (FINS) and leptin levels." | 7.85 | Effects of Exercise Intervention on Preventing Letrozole-Exposed Rats From Polycystic Ovary Syndrome. ( Cao, SF; Hu, WL; Jiang, LY; Wu, MM, 2017) |
| " First, letrozole was used to induce the PCOS model, 24 h food intake, 24 h body weight changes and the expression of p-STAT3 were determined following leptin or artificial cerebrospinal fluid (aCSF) icv injection in rats." | 7.83 | Central leptin resistance and hypothalamic inflammation are involved in letrozole-induced polycystic ovary syndrome rats. ( Lian, Y; Wang, W; Zhao, F, 2016) |
| "A rat model of PCOS-IR was established using a high-fat diet (49 d) combined with letrozole (1 mg/kg·d, for 28 d)." | 5.62 | Effects of total flavonoids from Eucommia ulmoides Oliv. leaves on polycystic ovary syndrome with insulin resistance model rats induced by letrozole combined with a high-fat diet. ( Li, CX; Li, M; Miao, MS; Peng, MF; Ren, Z; Song, YG; Tian, S, 2021) |
| "Polycystic ovary syndrome is one of the most common causes of female infertility, affecting 5-10% of the population." | 5.51 | Ocimum kilimandscharicum L. restores ovarian functions in letrozole - induced Polycystic Ovary Syndrome (PCOS) in rats: Comparison with metformin. ( AbdelMaksoud, S; El-Bahy, AA; Handoussa, H; Khaled, N; Radwan, R, 2019) |
| " A total of 750 infertile women with polycystic ovary syndrome (PCOS) were randomly assigned to up to receive five cycles of letrozole or clomiphene citrate." | 5.20 | Impact of Male and Female Weight, Smoking, and Intercourse Frequency on Live Birth in Women With Polycystic Ovary Syndrome. ( Allshouse, AA; Alvero, R; Casson, PR; Christman, GM; Coutifaris, C; Diamond, MP; Eisenberg, E; Krawetz, SA; Legro, RS; Polotsky, AJ; Santoro, N; Schlaff, WD; Trussell, JC; Zhang, H, 2015) |
| " Age, body weight (WT), AST, ALT, total bilirubin, serum creatinine (CRE), and genotype of CYP2A6 were studied as covariates." | 5.15 | Population pharmacokinetic analysis of letrozole in Japanese postmenopausal women. ( Horie, T; Shitara, Y; Tanii, H, 2011) |
| " In contrast, in the testosterone-plus-letrozole-treated group, the concentration decreased during letrozole treatment, indicating improved insulin sensitivity." | 5.10 | The role of sex steroids in the regulation of insulin sensitivity and serum lipid concentrations during male puberty: a prospective study with a P450-aromatase inhibitor. ( Dunkel, L; Saukkonen, T; Wickman, S, 2002) |
| " Interestingly, naringenin supplementation significantly reduced body weight, ameliorated hormone levels, improved insulin resistance, and mitigated pathological changes in ovarian tissue, up-regulated the expression of PGC-1ɑ, SIRT1, occludin and claudin-1 in colon." | 4.12 | Naringenin regulates gut microbiota and SIRT1/ PGC-1ɑ signaling pathway in rats with letrozole-induced polycystic ovary syndrome. ( An, T; Bao, XL; Gao, L; Han, BS; Hu, YY; Jiang, GJ; Lian, J; Lv, BH; Wang, TY; Wu, YX; Yang, XY, 2022) |
| " To that end, we have established a Swiss albino mouse model of PCOS based on 3 weeks of daily treatment with letrozole (50 μg/day; intraperitoneal) and dehydroepiandrosterone (DHEA, 6 mg/100 g body weight; subcutaneous) in 5-week-old female mice fed on normal or high-fat diet (HFD)." | 4.12 | Distinctions in PCOS Induced by Letrozole Vs Dehydroepiandrosterone With High-fat Diet in Mouse Model. ( Adiga, SK; Bakkum-Gamez, J; Chang, AY; DeStephano, C; Kalthur, G; Kalthur, SG; Kannan, N; Kundapur, SD; Mutalik, S; Nayak, G; Panchanan, G; Poojary, PS; Rao, A; Sherman, M; Zhao, Y, 2022) |
| "Letrozole-treated rats showed successful induction of PCOS, confirmed by histopathology and significantly increased body weight, testosterone, insulin, AMH, and MDA, and decreased SOD." | 4.12 | Fenofibrate ameliorates letrozole-induced polycystic ovary in rats via modulation of PPARα and TNFα/CD95 pathway. ( El-Hussieny, M; Morsy, MA; Nair, AB; Refaie, MMM; Venugopala, KN; Zenhom, NM, 2022) |
| "BACKGROUND The aim of this study was to explore whether letrozole and high-fat diets (HFD) can induce obese insulin-resistant polycystic ovary syndrome (PCOS) with all reproductive and metabolic phenotypes in a rat model." | 3.96 | Letrozole Rat Model Mimics Human Polycystic Ovarian Syndrome and Changes in Insulin Signal Pathways. ( Dun, J; Huang, L; Huang, M; Ji, F; Lin, Q; Lin, Y; Xu, J; Yang, J; You, X; Zhang, J, 2020) |
| " The study investigated the effects of quercetin in a letrozole induced rat model of polycystic ovarian syndrome, which displayed both clinical and metabolic features as in PCOS women." | 3.88 | Therapeutic potentials of Quercetin in management of polycystic ovarian syndrome using Letrozole induced rat model: a histological and a biochemical study. ( Abid, A; Afsar, T; Almajwal, A; Jahan, S; Khalid, S; Razak, S; Shaheen, G, 2018) |
| "To evaluate the effect of metformin and pioglitazone on leutinizing hormone and follicle stimulating hormone receptor mRNA expression, hyperandrogenism and insulin resistance in high fat diet induced and letrozole induced PCOS in rats." | 3.88 | Insulin Sensitizers Modulate GnRH Receptor Expression in PCOS Rats. ( Patel, R; Shah, G, 2018) |
| "Here we hypothesized that exercise in dihydrotestosterone (DHT) or letrozole (LET)-induced polycystic ovary syndrome mouse models improves impaired insulin and glucose metabolism, adipose tissue morphology, and expression of genes related to adipogenesis, lipid metabolism, Notch pathway and browning in inguinal and mesenteric fat." | 3.85 | Exercise differentially affects metabolic functions and white adipose tissue in female letrozole- and dihydrotestosterone-induced mouse models of polycystic ovary syndrome. ( Benrick, A; Carlström, M; Cushman, SW; Fornes, R; Hu, M; Ivarsson, N; Maciel, GAR; Maliqueo, M; Marcondes, RR; Stener-Victorin, E; Stenkula, KG, 2017) |
| " The study was undertaken to investigate the possible protective and ameliorating effects of GABA in Letrozole induced PCOS model in rats by targeting insulin resistance." | 3.85 | Protective effects of GABA against metabolic and reproductive disturbances in letrozole induced polycystic ovarian syndrome in rats. ( Afsar, T; Almajwal, A; Jahan, S; Pirzada, M; Rauf, N; Razak, S; Ullah, A; Ullah, H, 2017) |
| " Polycystic ovary syndrome was induced by letrozole administration, and animals presented with obesity, sex hormone disorder, no ovulation, large cystic follicles, and increasing fasting insulin (FINS) and leptin levels." | 3.85 | Effects of Exercise Intervention on Preventing Letrozole-Exposed Rats From Polycystic Ovary Syndrome. ( Cao, SF; Hu, WL; Jiang, LY; Wu, MM, 2017) |
| " First, letrozole was used to induce the PCOS model, 24 h food intake, 24 h body weight changes and the expression of p-STAT3 were determined following leptin or artificial cerebrospinal fluid (aCSF) icv injection in rats." | 3.83 | Central leptin resistance and hypothalamic inflammation are involved in letrozole-induced polycystic ovary syndrome rats. ( Lian, Y; Wang, W; Zhao, F, 2016) |
| "A rat model of PCOS-IR was established using a high-fat diet (49 d) combined with letrozole (1 mg/kg·d, for 28 d)." | 1.62 | Effects of total flavonoids from Eucommia ulmoides Oliv. leaves on polycystic ovary syndrome with insulin resistance model rats induced by letrozole combined with a high-fat diet. ( Li, CX; Li, M; Miao, MS; Peng, MF; Ren, Z; Song, YG; Tian, S, 2021) |
| " Following plasma letrozole dosage at the end of the experiment (day 73), only rats with at least 90 ng/ml of letrozole were considered significantly exposed to letrozole (OVX + high LTZ group), whereas treated animals with less than 90 ng/ml were pooled in the OVX + low LTZ group." | 1.62 | A new clinically-relevant rat model of letrozole-induced chronic nociceptive disorders. ( Amode, R; Balayssac, D; Collin, A; Eschalier, A; Guillet, C; Pereira, B; Richard, D; Vein, J; Wittrant, Y, 2021) |
| " The present study evaluated the effect of testosterone itself and combined with letrozole, an aromatase inhibitor, on bone mineral density of male rats." | 1.51 | The effect of testosterone itself and in combination with letrozole on bone mineral density in male rats. ( Kasaee, SR; Ranjbar Omrani, GH; Sadeghian, F; Saki, F; Talezadeh, P, 2019) |
| "Polycystic ovary syndrome is one of the most common causes of female infertility, affecting 5-10% of the population." | 1.51 | Ocimum kilimandscharicum L. restores ovarian functions in letrozole - induced Polycystic Ovary Syndrome (PCOS) in rats: Comparison with metformin. ( AbdelMaksoud, S; El-Bahy, AA; Handoussa, H; Khaled, N; Radwan, R, 2019) |
| "Flutamide treatment in LET females reversed elevated T levels and restored ovarian expression of Cyp17a1 (critical for androgen synthesis) to normal levels." | 1.48 | Antiandrogen Treatment Ameliorates Reproductive and Metabolic Phenotypes in the Letrozole-Induced Mouse Model of PCOS. ( Malik, S; Mellon, PL; Ryan, GE, 2018) |
| "In letrozole - treated animals in comparison with untreated animals, increased plasmatic triacylglycerol concentrations (P<0." | 1.35 | Preventive effects of letrozole in the model of premenopausal mammary carcinogenesis. ( Fetisovova, Z; Kajo, K; Kubatka, P; Nosalova, G; Sadlonova, V, 2008) |
| "All letrozole rats were anovulatory and developed polycystic ovaries with structural changes strikingly similar to those in human PCOS." | 1.34 | A new rat model exhibiting both ovarian and metabolic characteristics of polycystic ovary syndrome. ( Cajander, S; Holmäng, A; Lönn, M; Lystig, T; Mannerås, L; Seleskovic, Z; Stener-Victorin, E, 2007) |
| "Letrozole was administered per os daily in a dose of 1 mg/kg b." | 1.34 | [The role of the ovarian steroid aromatase in pathogenesis of reproductive cycles disorders]. ( Reznikov, OH; Tarasenko, LV, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (25.00) | 29.6817 |
| 2010's | 18 (56.25) | 24.3611 |
| 2020's | 6 (18.75) | 2.80 |
| Authors | Studies |
|---|---|
| Farag, AM | 1 |
| Ali, KA | 1 |
| El-Debss, TM | 1 |
| Mayhoub, AS | 1 |
| Amr, AG | 1 |
| Abdel-Hafez, NA | 1 |
| Abdulla, MM | 1 |
| Wu, YX | 1 |
| Yang, XY | 1 |
| Han, BS | 1 |
| Hu, YY | 1 |
| An, T | 1 |
| Lv, BH | 1 |
| Lian, J | 1 |
| Wang, TY | 1 |
| Bao, XL | 1 |
| Gao, L | 1 |
| Jiang, GJ | 1 |
| Poojary, PS | 1 |
| Nayak, G | 1 |
| Panchanan, G | 1 |
| Rao, A | 1 |
| Kundapur, SD | 1 |
| Kalthur, SG | 1 |
| Mutalik, S | 1 |
| Adiga, SK | 1 |
| Zhao, Y | 1 |
| Bakkum-Gamez, J | 1 |
| Chang, AY | 1 |
| DeStephano, C | 1 |
| Sherman, M | 1 |
| Kannan, N | 1 |
| Kalthur, G | 1 |
| Morsy, MA | 1 |
| El-Hussieny, M | 1 |
| Zenhom, NM | 1 |
| Nair, AB | 1 |
| Venugopala, KN | 1 |
| Refaie, MMM | 1 |
| Xu, J | 1 |
| Dun, J | 1 |
| Yang, J | 1 |
| Zhang, J | 1 |
| Lin, Q | 1 |
| Huang, M | 1 |
| Ji, F | 1 |
| Huang, L | 1 |
| You, X | 1 |
| Lin, Y | 1 |
| Peng, MF | 1 |
| Tian, S | 1 |
| Song, YG | 1 |
| Li, CX | 1 |
| Miao, MS | 1 |
| Ren, Z | 1 |
| Li, M | 1 |
| Collin, A | 1 |
| Vein, J | 1 |
| Wittrant, Y | 1 |
| Pereira, B | 1 |
| Amode, R | 1 |
| Guillet, C | 1 |
| Richard, D | 1 |
| Eschalier, A | 1 |
| Balayssac, D | 1 |
| Marcondes, RR | 1 |
| Maliqueo, M | 1 |
| Fornes, R | 1 |
| Benrick, A | 1 |
| Hu, M | 1 |
| Ivarsson, N | 1 |
| Carlström, M | 1 |
| Cushman, SW | 1 |
| Stenkula, KG | 1 |
| Maciel, GAR | 1 |
| Stener-Victorin, E | 3 |
| Ullah, A | 1 |
| Jahan, S | 2 |
| Razak, S | 2 |
| Pirzada, M | 1 |
| Ullah, H | 1 |
| Almajwal, A | 2 |
| Rauf, N | 1 |
| Afsar, T | 2 |
| Makary, S | 1 |
| Abdo, M | 1 |
| Fekry, E | 1 |
| Ryan, GE | 1 |
| Malik, S | 1 |
| Mellon, PL | 1 |
| Abid, A | 1 |
| Khalid, S | 1 |
| Shaheen, G | 1 |
| Patel, R | 1 |
| Shah, G | 1 |
| Saki, F | 1 |
| Kasaee, SR | 1 |
| Sadeghian, F | 1 |
| Talezadeh, P | 1 |
| Ranjbar Omrani, GH | 1 |
| Ragy, MM | 1 |
| Abdel-Hamid, HA | 1 |
| Toni, NDM | 1 |
| Khaled, N | 1 |
| El-Bahy, AA | 1 |
| Radwan, R | 1 |
| Handoussa, H | 1 |
| AbdelMaksoud, S | 1 |
| Pouliot, L | 1 |
| Schneider, M | 1 |
| DeCristofaro, M | 1 |
| Samadfam, R | 1 |
| Smith, SY | 1 |
| Beckman, DA | 1 |
| Polotsky, AJ | 1 |
| Allshouse, AA | 1 |
| Casson, PR | 1 |
| Coutifaris, C | 1 |
| Diamond, MP | 1 |
| Christman, GM | 1 |
| Schlaff, WD | 1 |
| Alvero, R | 1 |
| Trussell, JC | 1 |
| Krawetz, SA | 1 |
| Santoro, N | 1 |
| Eisenberg, E | 1 |
| Zhang, H | 1 |
| Legro, RS | 1 |
| Birch Petersen, K | 1 |
| Pedersen, NG | 1 |
| Pedersen, AT | 1 |
| Lauritsen, MP | 1 |
| la Cour Freiesleben, N | 1 |
| Lian, Y | 1 |
| Zhao, F | 1 |
| Wang, W | 1 |
| Cao, SF | 1 |
| Hu, WL | 1 |
| Wu, MM | 1 |
| Jiang, LY | 1 |
| Gerardin, DC | 1 |
| Piffer, RC | 1 |
| Garcia, PC | 1 |
| Moreira, EG | 1 |
| Pereira, OC | 1 |
| Aberdeen, GW | 1 |
| Baschat, AA | 1 |
| Harman, CR | 1 |
| Weiner, CP | 1 |
| Langenberg, PW | 1 |
| Pepe, GJ | 1 |
| Albrecht, ED | 1 |
| Tanii, H | 1 |
| Shitara, Y | 1 |
| Horie, T | 1 |
| Ortega, I | 1 |
| Sokalska, A | 1 |
| Villanueva, JA | 1 |
| Cress, AB | 1 |
| Wong, DH | 1 |
| Stanley, SD | 1 |
| Duleba, AJ | 1 |
| Eshet, R | 1 |
| Maor, G | 1 |
| Ben Ari, T | 1 |
| Ben Eliezer, M | 1 |
| Gat-Yablonski, G | 1 |
| Phillip, M | 1 |
| Gasser, JA | 1 |
| Green, JR | 1 |
| Shen, V | 1 |
| Ingold, P | 1 |
| Rebmann, A | 1 |
| Bhatnagar, AS | 1 |
| Evans, DB | 1 |
| Santos, FC | 1 |
| Falleiros-Júnior, LR | 1 |
| Corradi, LS | 1 |
| Vilamaior, PS | 1 |
| Taboga, SR | 1 |
| Mannerås, L | 1 |
| Cajander, S | 1 |
| Holmäng, A | 1 |
| Seleskovic, Z | 1 |
| Lystig, T | 1 |
| Lönn, M | 1 |
| Tarasenko, LV | 1 |
| Reznikov, OH | 1 |
| Kubatka, P | 1 |
| Sadlonova, V | 1 |
| Kajo, K | 1 |
| Nosalova, G | 1 |
| Fetisovova, Z | 1 |
| Wickman, S | 1 |
| Saukkonen, T | 1 |
| Dunkel, L | 1 |
2 reviews available for letrozole and Body Weight
| Article | Year |
|---|---|
Pathophysiological changes in experimental polycystic ovary syndrome in female albino rats: Using either hemin or L-arginine.
Topics: Animals; Arginine; Aromatase Inhibitors; Body Weight; Female; Gasotransmitters; Hemin; Humans; Letro | 2019 |
Mono-ovulation in women with polycystic ovary syndrome: a clinical review on ovulation induction.
Topics: Adult; Anovulation; Body Weight; Clomiphene; Female; Fertility Agents, Female; Gonadotropins; Humans | 2016 |
3 trials available for letrozole and Body Weight
| Article | Year |
|---|---|
Impact of Male and Female Weight, Smoking, and Intercourse Frequency on Live Birth in Women With Polycystic Ovary Syndrome.
Topics: Adolescent; Adult; Body Mass Index; Body Weight; Clomiphene; Coitus; Female; Fertility Agents, Femal | 2015 |
Population pharmacokinetic analysis of letrozole in Japanese postmenopausal women.
Topics: Aged; Antineoplastic Agents; Aromatase Inhibitors; Aryl Hydrocarbon Hydroxylases; Asian People; Bili | 2011 |
The role of sex steroids in the regulation of insulin sensitivity and serum lipid concentrations during male puberty: a prospective study with a P450-aromatase inhibitor.
Topics: Adolescent; Aromatase Inhibitors; Body Composition; Body Height; Body Weight; Double-Blind Method; E | 2002 |
27 other studies available for letrozole and Body Weight
| Article | Year |
|---|---|
Design, synthesis and structure-activity relationship study of novel pyrazole-based heterocycles as potential antitumor agents.
Topics: Animals; Antineoplastic Agents; Body Weight; Cell Line, Tumor; Cell Proliferation; Cyclization; Dose | 2010 |
Naringenin regulates gut microbiota and SIRT1/ PGC-1ɑ signaling pathway in rats with letrozole-induced polycystic ovary syndrome.
Topics: Animals; Body Weight; Claudin-1; Female; Flavanones; Gastrointestinal Microbiome; Hormones; Humans; | 2022 |
Distinctions in PCOS Induced by Letrozole Vs Dehydroepiandrosterone With High-fat Diet in Mouse Model.
Topics: Animals; Body Weight; Dehydroepiandrosterone; Diet, High-Fat; Disease Models, Animal; Female; Humans | 2022 |
Fenofibrate ameliorates letrozole-induced polycystic ovary in rats via modulation of PPARα and TNFα/CD95 pathway.
Topics: Animals; Anti-Mullerian Hormone; Body Weight; Disease Models, Animal; Female; Fenofibrate; Humans; I | 2022 |
Letrozole Rat Model Mimics Human Polycystic Ovarian Syndrome and Changes in Insulin Signal Pathways.
Topics: Animals; Body Weight; Diet, High-Fat; Disease Models, Animal; Estrous Cycle; Female; Insulin; Insuli | 2020 |
Effects of total flavonoids from Eucommia ulmoides Oliv. leaves on polycystic ovary syndrome with insulin resistance model rats induced by letrozole combined with a high-fat diet.
Topics: Animals; Body Weight; Diet, High-Fat; Disease Models, Animal; Eucommiaceae; Female; Flavonoids; Gona | 2021 |
A new clinically-relevant rat model of letrozole-induced chronic nociceptive disorders.
Topics: Animals; Aromatase Inhibitors; Body Weight; Chronic Disease; Disease Models, Animal; Female; Ganglia | 2021 |
Exercise differentially affects metabolic functions and white adipose tissue in female letrozole- and dihydrotestosterone-induced mouse models of polycystic ovary syndrome.
Topics: Adipocytes; Adipogenesis; Adipose Tissue, White; Animals; Body Composition; Body Weight; Cell Size; | 2017 |
Protective effects of GABA against metabolic and reproductive disturbances in letrozole induced polycystic ovarian syndrome in rats.
Topics: Androgen Antagonists; Animals; Blood Glucose; Body Weight; Catalase; Estradiol; Female; gamma-Aminob | 2017 |
Oxidative stress burden inhibits spermatogenesis in adult male rats: testosterone protective effect.
Topics: Aging; Animals; Biomarkers; Body Weight; Estradiol; Follicle Stimulating Hormone; Grape Seed Extract | 2018 |
Antiandrogen Treatment Ameliorates Reproductive and Metabolic Phenotypes in the Letrozole-Induced Mouse Model of PCOS.
Topics: Adipocytes; Androgen Antagonists; Animals; Aromatase Inhibitors; Body Weight; Disease Models, Animal | 2018 |
Therapeutic potentials of Quercetin in management of polycystic ovarian syndrome using Letrozole induced rat model: a histological and a biochemical study.
Topics: Animals; Antioxidants; Biomarkers; Biopsy; Body Weight; Disease Management; Disease Models, Animal; | 2018 |
Insulin Sensitizers Modulate GnRH Receptor Expression in PCOS Rats.
Topics: Animals; Body Weight; Carboxymethylcellulose Sodium; Diet, High-Fat; Female; Glucose Tolerance Test; | 2018 |
The effect of testosterone itself and in combination with letrozole on bone mineral density in male rats.
Topics: Absorptiometry, Photon; Animals; Biomarkers; Body Weight; Bone Density; Femur; Letrozole; Lumbar Ver | 2019 |
Ocimum kilimandscharicum L. restores ovarian functions in letrozole - induced Polycystic Ovary Syndrome (PCOS) in rats: Comparison with metformin.
Topics: Aged; Animals; Antioxidants; Aromatase Inhibitors; Blood Glucose; Body Weight; Chromatography, High | 2019 |
Assessment of a nonsteroidal aromatase inhibitor, letrozole, in juvenile rats.
Topics: Animals; Aromatase Inhibitors; Behavior, Animal; Body Weight; Bone Development; Dose-Response Relati | 2013 |
Central leptin resistance and hypothalamic inflammation are involved in letrozole-induced polycystic ovary syndrome rats.
Topics: Animals; Body Weight; Eating; Female; Hypothalamus; Inflammation; Leptin; Letrozole; Nitriles; Ovary | 2016 |
Effects of Exercise Intervention on Preventing Letrozole-Exposed Rats From Polycystic Ovary Syndrome.
Topics: Animals; Aromatase Inhibitors; Body Weight; Disease Models, Animal; Female; Follicle Stimulating Hor | 2017 |
Effects of maternal exposure to an aromatase inhibitor on sexual behaviour and neurochemical and endocrine aspects of adult male rat.
Topics: Animals; Aromatase Inhibitors; Biogenic Monoamines; Body Weight; Brain Chemistry; Endocrine System; | 2008 |
Uterine and fetal blood flow indexes and fetal growth assessment after chronic estrogen suppression in the second half of baboon pregnancy.
Topics: Animals; Aromatase Inhibitors; Blood Pressure; Body Weight; Estradiol; Estrogens; Female; Fetal Deve | 2010 |
Letrozole increases ovarian growth and Cyp17a1 gene expression in the rat ovary.
Topics: Animals; Aromatase Inhibitors; Bacterial Proteins; Body Weight; Cell Proliferation; Cells, Cultured; | 2013 |
The aromatase inhibitor letrozole increases epiphyseal growth plate height and tibial length in peripubertal male mice.
Topics: Animals; Aromatase; Aromatase Inhibitors; Body Weight; Collagen; Collagen Type II; Collagen Type X; | 2004 |
A single intravenous administration of zoledronic acid prevents the bone loss and mechanical compromise induced by aromatase inhibition in rats.
Topics: Animals; Aromatase Inhibitors; Biomechanical Phenomena; Body Weight; Bone and Bones; Bone Density; B | 2006 |
Experimental endocrine therapies promote epithelial cytodifferentiation and ciliogenesis in the gerbil female prostate.
Topics: Animals; Body Weight; Cell Differentiation; Cilia; Epithelial Cells; Female; Gerbillinae; Gonadal St | 2007 |
A new rat model exhibiting both ovarian and metabolic characteristics of polycystic ovary syndrome.
Topics: Adipocytes; Androgens; Animals; Aromatase Inhibitors; Body Composition; Body Weight; Dihydrotestoste | 2007 |
[The role of the ovarian steroid aromatase in pathogenesis of reproductive cycles disorders].
Topics: Administration, Oral; Anestrus; Animals; Aromatase; Aromatase Inhibitors; Body Weight; Estrous Cycle | 2007 |
Preventive effects of letrozole in the model of premenopausal mammary carcinogenesis.
Topics: Animals; Anticarcinogenic Agents; Body Weight; Drug Screening Assays, Antitumor; Female; Letrozole; | 2008 |