Page last updated: 2024-10-30

letrozole and Allodynia

letrozole has been researched along with Allodynia in 3 studies

Research Excerpts

ExcerptRelevanceReference
"The decrease in mechanical hyperalgesia in OVX females was mirrored by significant decreases in spinal astrocyte activity in laminae I-II, III-IV, V-VI and X and aromatase expression in laminae V-VI and X in the dorsal horn of tumor-bearing animals."1.43The relationship of bone-tumor-induced spinal cord astrocyte activation and aromatase expression to mechanical hyperalgesia and cold hypersensitivity in intact female and ovariectomized mice. ( Beitz, AJ; Lee, JH; Michlitsch, KS; O'Brien, EE; Smeester, BA, 2016)
" Repeated injection of 5mg/kg letrozole in male rats produced mechanical, but not thermal, hypersensitivity that extinguished when drug dosing was stopped."1.43Aromatase inhibitors augment nociceptive behaviors in rats and enhance the excitability of sensory neurons. ( Duarte, DB; Flockhart, DA; Robarge, JD; Shariati, B; Vasko, MR; Wang, R, 2016)
"Here, we examined tumor-induced mechanical hyperalgesia and cold allodynia, and changes in Glial fibrillary acid protein (GFAP) and aromatase expression in murine models of painful and non-painful bone cancer."1.42Colocalization of aromatase in spinal cord astrocytes: differences in expression and relationship to mechanical and thermal hyperalgesia in murine models of a painful and a non-painful bone tumor. ( Beitz, AJ; Lee, JH; Michlitsch, KS; O'Brien, EE; Smeester, BA, 2015)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
O'Brien, EE2
Smeester, BA2
Michlitsch, KS2
Lee, JH2
Beitz, AJ2
Robarge, JD1
Duarte, DB1
Shariati, B1
Wang, R1
Flockhart, DA1
Vasko, MR1

Other Studies

3 other studies available for letrozole and Allodynia

ArticleYear
Colocalization of aromatase in spinal cord astrocytes: differences in expression and relationship to mechanical and thermal hyperalgesia in murine models of a painful and a non-painful bone tumor.
    Neuroscience, 2015, Aug-20, Volume: 301

    Topics: Analysis of Variance; Animals; Antineoplastic Agents; Aromatase; Bone Neoplasms; Cell Line, Tumor; D

2015
The relationship of bone-tumor-induced spinal cord astrocyte activation and aromatase expression to mechanical hyperalgesia and cold hypersensitivity in intact female and ovariectomized mice.
    Neuroscience, 2016, Jun-02, Volume: 324

    Topics: Animals; Aromatase; Aromatase Inhibitors; Astrocytes; Bone Neoplasms; Cancer Pain; Cold Temperature;

2016
Aromatase inhibitors augment nociceptive behaviors in rats and enhance the excitability of sensory neurons.
    Experimental neurology, 2016, Volume: 281

    Topics: Adenosine Triphosphate; Androstadienes; Animals; Aromatase Inhibitors; Calcitonin Gene-Related Pepti

2016