Page last updated: 2024-10-30

letrozole and Ache

letrozole has been researched along with Ache in 10 studies

Research Excerpts

ExcerptRelevanceReference
"To compare the efficacy and the tolerability of letrozole combined with oral contraceptives versus oral contraceptives alone in treating endometriosis-related pain."9.41Letrozole combined with oral contraceptives versus oral contraceptives alone in the treatment of endometriosis-related pain symptoms: a pilot study. ( Luan, X; Wang, Y; Zhao, Y, 2021)
"17, a placebo-controlled trial of letrozole following 5 years of tamoxifen in postmenopausal women with early stage breast cancer."9.12Clinical outcomes of ethnic minority women in MA.17: a trial of letrozole after 5 years of tamoxifen in postmenopausal women with early stage breast cancer. ( Goss, PE; Ingle, JN; Moy, B; Pater, JL; Shepherd, LE; Tu, D; Whelan, TJ, 2006)
"We examined 12 consecutive non-metastatic breast cancer patients who reported severe musculoskeletal pain under a third generation AI; 11 were on letrozole and 1 on exemestane."7.74Debilitating musculoskeletal pain and stiffness with letrozole and exemestane: associated tenosynovial changes on magnetic resonance imaging. ( Amant, F; Berteloot, P; Christiaens, MR; De Smet, L; Leunen, K; Morales, L; Neven, P; Pans, S; Paridaens, R; Smeets, A; Timmerman, D; Van den Bogaert, W; Van Limbergen, E; Vergote, I; Verhaeghe, J; Weltens, C; Westhovens, R; Wildiers, H, 2007)
"Endocrine treatments of breast cancer patients antagonize estrogen and may lead to consequences of estrogen deprivation including menopausal symptoms."6.71Acute effects of tamoxifen and third-generation aromatase inhibitors on menopausal symptoms of breast cancer patients. ( Ameye, L; Carbonez, A; Christiaens, MR; Morales, L; Neven, P; Paridaens, R; Timmerman, D; Van Huffel, S; Van Limbergen, E; Vergote, I, 2004)
"To compare the efficacy and the tolerability of letrozole combined with oral contraceptives versus oral contraceptives alone in treating endometriosis-related pain."5.41Letrozole combined with oral contraceptives versus oral contraceptives alone in the treatment of endometriosis-related pain symptoms: a pilot study. ( Luan, X; Wang, Y; Zhao, Y, 2021)
"17, a placebo-controlled trial of letrozole following 5 years of tamoxifen in postmenopausal women with early stage breast cancer."5.12Clinical outcomes of ethnic minority women in MA.17: a trial of letrozole after 5 years of tamoxifen in postmenopausal women with early stage breast cancer. ( Goss, PE; Ingle, JN; Moy, B; Pater, JL; Shepherd, LE; Tu, D; Whelan, TJ, 2006)
"Use of aromatase inhibitors (AIs), exemestane, letrozole and anastrozole, for breast cancer therapy is associated with severe pain symptoms, the underlying mechanism of which is unknown."3.80Steroidal and non-steroidal third-generation aromatase inhibitors induce pain-like symptoms via TRPA1. ( Benemei, S; Coppi, E; De Logu, F; Di Tommaso, MR; Fusi, C; Geppetti, P; Marone, IM; Materazzi, S; Minocci, D; Moneti, G; Nassini, R; Pieraccini, G; Susini, T; Trevisan, G; Tuccinardi, T, 2014)
"Two premenopausal patients with bladder endometriosis were treated with letrozole (2."3.77Aromatase inhibitors in the treatment of bladder endometriosis. ( Biscaldi, E; Ferrero, S; Luigi Venturini, P; Remorgida, V, 2011)
"We examined 12 consecutive non-metastatic breast cancer patients who reported severe musculoskeletal pain under a third generation AI; 11 were on letrozole and 1 on exemestane."3.74Debilitating musculoskeletal pain and stiffness with letrozole and exemestane: associated tenosynovial changes on magnetic resonance imaging. ( Amant, F; Berteloot, P; Christiaens, MR; De Smet, L; Leunen, K; Morales, L; Neven, P; Pans, S; Paridaens, R; Smeets, A; Timmerman, D; Van den Bogaert, W; Van Limbergen, E; Vergote, I; Verhaeghe, J; Weltens, C; Westhovens, R; Wildiers, H, 2007)
"Endocrine treatments of breast cancer patients antagonize estrogen and may lead to consequences of estrogen deprivation including menopausal symptoms."2.71Acute effects of tamoxifen and third-generation aromatase inhibitors on menopausal symptoms of breast cancer patients. ( Ameye, L; Carbonez, A; Christiaens, MR; Morales, L; Neven, P; Paridaens, R; Timmerman, D; Van Huffel, S; Van Limbergen, E; Vergote, I, 2004)
"Here, we examined tumor-induced mechanical hyperalgesia and cold allodynia, and changes in Glial fibrillary acid protein (GFAP) and aromatase expression in murine models of painful and non-painful bone cancer."1.42Colocalization of aromatase in spinal cord astrocytes: differences in expression and relationship to mechanical and thermal hyperalgesia in murine models of a painful and a non-painful bone tumor. ( Beitz, AJ; Lee, JH; Michlitsch, KS; O'Brien, EE; Smeester, BA, 2015)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (40.00)29.6817
2010's5 (50.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Zhao, Y1
Luan, X1
Wang, Y1
Fusi, C1
Materazzi, S1
Benemei, S1
Coppi, E1
Trevisan, G1
Marone, IM1
Minocci, D1
De Logu, F1
Tuccinardi, T1
Di Tommaso, MR1
Susini, T1
Moneti, G1
Pieraccini, G1
Geppetti, P1
Nassini, R1
O'Brien, EE1
Smeester, BA1
Michlitsch, KS1
Lee, JH1
Beitz, AJ1
Schaeffer, V1
Meyer, L1
Patte-Mensah, C1
Eckert, A1
Mensah-Nyagan, AG1
Ferrero, S1
Biscaldi, E1
Luigi Venturini, P1
Remorgida, V1
Moradi-Azani, M1
Ahmadiani, A1
Amini, H1
Morales, L2
Neven, P2
Timmerman, D2
Christiaens, MR2
Vergote, I2
Van Limbergen, E2
Carbonez, A1
Van Huffel, S1
Ameye, L1
Paridaens, R2
Whelan, TJ2
Goss, PE2
Ingle, JN2
Pater, JL2
Tu, D2
Pritchard, K1
Liu, S1
Shepherd, LE2
Palmer, M1
Robert, NJ1
Martino, S1
Muss, HB1
Moy, B1
Pans, S1
Westhovens, R1
Verhaeghe, J1
Wildiers, H1
Leunen, K1
Amant, F1
Berteloot, P1
Smeets, A1
Weltens, C1
Van den Bogaert, W1
De Smet, L1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase III Randomized Double Blind Study of Letrozole Versus Placebo in Women With Primary Breast Cancer Completing Five or More Years of Adjuvant Tamoxifen[NCT00003140]Phase 35,187 participants (Actual)Interventional1998-08-24Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

4 trials available for letrozole and Ache

ArticleYear
Letrozole combined with oral contraceptives versus oral contraceptives alone in the treatment of endometriosis-related pain symptoms: a pilot study.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2021, Volume: 37, Issue:1

    Topics: Adult; Aromatase Inhibitors; Contraceptives, Oral, Hormonal; Desogestrel; Drug Therapy, Combination;

2021
Acute effects of tamoxifen and third-generation aromatase inhibitors on menopausal symptoms of breast cancer patients.
    Anti-cancer drugs, 2004, Volume: 15, Issue:8

    Topics: Anastrozole; Aromatase Inhibitors; Belgium; Body Mass Index; Breast Neoplasms; Data Interpretation,

2004
Assessment of quality of life in MA.17: a randomized, placebo-controlled trial of letrozole after 5 years of tamoxifen in postmenopausal women.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Oct-01, Volume: 23, Issue:28

    Topics: Administration, Oral; Aged; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms;

2005
Clinical outcomes of ethnic minority women in MA.17: a trial of letrozole after 5 years of tamoxifen in postmenopausal women with early stage breast cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2006, Volume: 17, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherap

2006

Other Studies

6 other studies available for letrozole and Ache

ArticleYear
Steroidal and non-steroidal third-generation aromatase inhibitors induce pain-like symptoms via TRPA1.
    Nature communications, 2014, Dec-08, Volume: 5

    Topics: Anastrozole; Androstadienes; Animals; Aromatase Inhibitors; Behavior, Animal; Calcium; Calcium Chann

2014
Colocalization of aromatase in spinal cord astrocytes: differences in expression and relationship to mechanical and thermal hyperalgesia in murine models of a painful and a non-painful bone tumor.
    Neuroscience, 2015, Aug-20, Volume: 301

    Topics: Analysis of Variance; Animals; Antineoplastic Agents; Aromatase; Bone Neoplasms; Cell Line, Tumor; D

2015
Sciatic nerve injury induces apoptosis of dorsal root ganglion satellite glial cells and selectively modifies neurosteroidogenesis in sensory neurons.
    Glia, 2010, Jan-15, Volume: 58, Issue:2

    Topics: Animals; Apoptosis; Aromatase; Aromatase Inhibitors; Cell Survival; Estradiol; Ganglia, Spinal; Letr

2010
Aromatase inhibitors in the treatment of bladder endometriosis.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2011, Volume: 27, Issue:5

    Topics: Adult; Aromatase Inhibitors; Calcium; Cholecalciferol; Cystectomy; Drug Therapy, Combination; Endome

2011
Increase in formalin-induced tonic pain by 5alpha-reductase and aromatase inhibition in female rats.
    Pharmacology, biochemistry, and behavior, 2011, Volume: 98, Issue:1

    Topics: 5-alpha Reductase Inhibitors; Analgesics, Opioid; Animals; Aromatase Inhibitors; Drug Synergism; Fem

2011
Debilitating musculoskeletal pain and stiffness with letrozole and exemestane: associated tenosynovial changes on magnetic resonance imaging.
    Breast cancer research and treatment, 2007, Volume: 104, Issue:1

    Topics: Aged; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Carpal Tunnel Syndrome; Female; Humans

2007