letrozole has been researched along with Ache in 10 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the efficacy and the tolerability of letrozole combined with oral contraceptives versus oral contraceptives alone in treating endometriosis-related pain." | 9.41 | Letrozole combined with oral contraceptives versus oral contraceptives alone in the treatment of endometriosis-related pain symptoms: a pilot study. ( Luan, X; Wang, Y; Zhao, Y, 2021) |
| "17, a placebo-controlled trial of letrozole following 5 years of tamoxifen in postmenopausal women with early stage breast cancer." | 9.12 | Clinical outcomes of ethnic minority women in MA.17: a trial of letrozole after 5 years of tamoxifen in postmenopausal women with early stage breast cancer. ( Goss, PE; Ingle, JN; Moy, B; Pater, JL; Shepherd, LE; Tu, D; Whelan, TJ, 2006) |
| "We examined 12 consecutive non-metastatic breast cancer patients who reported severe musculoskeletal pain under a third generation AI; 11 were on letrozole and 1 on exemestane." | 7.74 | Debilitating musculoskeletal pain and stiffness with letrozole and exemestane: associated tenosynovial changes on magnetic resonance imaging. ( Amant, F; Berteloot, P; Christiaens, MR; De Smet, L; Leunen, K; Morales, L; Neven, P; Pans, S; Paridaens, R; Smeets, A; Timmerman, D; Van den Bogaert, W; Van Limbergen, E; Vergote, I; Verhaeghe, J; Weltens, C; Westhovens, R; Wildiers, H, 2007) |
| "Endocrine treatments of breast cancer patients antagonize estrogen and may lead to consequences of estrogen deprivation including menopausal symptoms." | 6.71 | Acute effects of tamoxifen and third-generation aromatase inhibitors on menopausal symptoms of breast cancer patients. ( Ameye, L; Carbonez, A; Christiaens, MR; Morales, L; Neven, P; Paridaens, R; Timmerman, D; Van Huffel, S; Van Limbergen, E; Vergote, I, 2004) |
| "To compare the efficacy and the tolerability of letrozole combined with oral contraceptives versus oral contraceptives alone in treating endometriosis-related pain." | 5.41 | Letrozole combined with oral contraceptives versus oral contraceptives alone in the treatment of endometriosis-related pain symptoms: a pilot study. ( Luan, X; Wang, Y; Zhao, Y, 2021) |
| "17, a placebo-controlled trial of letrozole following 5 years of tamoxifen in postmenopausal women with early stage breast cancer." | 5.12 | Clinical outcomes of ethnic minority women in MA.17: a trial of letrozole after 5 years of tamoxifen in postmenopausal women with early stage breast cancer. ( Goss, PE; Ingle, JN; Moy, B; Pater, JL; Shepherd, LE; Tu, D; Whelan, TJ, 2006) |
| "Use of aromatase inhibitors (AIs), exemestane, letrozole and anastrozole, for breast cancer therapy is associated with severe pain symptoms, the underlying mechanism of which is unknown." | 3.80 | Steroidal and non-steroidal third-generation aromatase inhibitors induce pain-like symptoms via TRPA1. ( Benemei, S; Coppi, E; De Logu, F; Di Tommaso, MR; Fusi, C; Geppetti, P; Marone, IM; Materazzi, S; Minocci, D; Moneti, G; Nassini, R; Pieraccini, G; Susini, T; Trevisan, G; Tuccinardi, T, 2014) |
| "Two premenopausal patients with bladder endometriosis were treated with letrozole (2." | 3.77 | Aromatase inhibitors in the treatment of bladder endometriosis. ( Biscaldi, E; Ferrero, S; Luigi Venturini, P; Remorgida, V, 2011) |
| "We examined 12 consecutive non-metastatic breast cancer patients who reported severe musculoskeletal pain under a third generation AI; 11 were on letrozole and 1 on exemestane." | 3.74 | Debilitating musculoskeletal pain and stiffness with letrozole and exemestane: associated tenosynovial changes on magnetic resonance imaging. ( Amant, F; Berteloot, P; Christiaens, MR; De Smet, L; Leunen, K; Morales, L; Neven, P; Pans, S; Paridaens, R; Smeets, A; Timmerman, D; Van den Bogaert, W; Van Limbergen, E; Vergote, I; Verhaeghe, J; Weltens, C; Westhovens, R; Wildiers, H, 2007) |
| "Endocrine treatments of breast cancer patients antagonize estrogen and may lead to consequences of estrogen deprivation including menopausal symptoms." | 2.71 | Acute effects of tamoxifen and third-generation aromatase inhibitors on menopausal symptoms of breast cancer patients. ( Ameye, L; Carbonez, A; Christiaens, MR; Morales, L; Neven, P; Paridaens, R; Timmerman, D; Van Huffel, S; Van Limbergen, E; Vergote, I, 2004) |
| "Here, we examined tumor-induced mechanical hyperalgesia and cold allodynia, and changes in Glial fibrillary acid protein (GFAP) and aromatase expression in murine models of painful and non-painful bone cancer." | 1.42 | Colocalization of aromatase in spinal cord astrocytes: differences in expression and relationship to mechanical and thermal hyperalgesia in murine models of a painful and a non-painful bone tumor. ( Beitz, AJ; Lee, JH; Michlitsch, KS; O'Brien, EE; Smeester, BA, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, Y | 1 |
| Luan, X | 1 |
| Wang, Y | 1 |
| Fusi, C | 1 |
| Materazzi, S | 1 |
| Benemei, S | 1 |
| Coppi, E | 1 |
| Trevisan, G | 1 |
| Marone, IM | 1 |
| Minocci, D | 1 |
| De Logu, F | 1 |
| Tuccinardi, T | 1 |
| Di Tommaso, MR | 1 |
| Susini, T | 1 |
| Moneti, G | 1 |
| Pieraccini, G | 1 |
| Geppetti, P | 1 |
| Nassini, R | 1 |
| O'Brien, EE | 1 |
| Smeester, BA | 1 |
| Michlitsch, KS | 1 |
| Lee, JH | 1 |
| Beitz, AJ | 1 |
| Schaeffer, V | 1 |
| Meyer, L | 1 |
| Patte-Mensah, C | 1 |
| Eckert, A | 1 |
| Mensah-Nyagan, AG | 1 |
| Ferrero, S | 1 |
| Biscaldi, E | 1 |
| Luigi Venturini, P | 1 |
| Remorgida, V | 1 |
| Moradi-Azani, M | 1 |
| Ahmadiani, A | 1 |
| Amini, H | 1 |
| Morales, L | 2 |
| Neven, P | 2 |
| Timmerman, D | 2 |
| Christiaens, MR | 2 |
| Vergote, I | 2 |
| Van Limbergen, E | 2 |
| Carbonez, A | 1 |
| Van Huffel, S | 1 |
| Ameye, L | 1 |
| Paridaens, R | 2 |
| Whelan, TJ | 2 |
| Goss, PE | 2 |
| Ingle, JN | 2 |
| Pater, JL | 2 |
| Tu, D | 2 |
| Pritchard, K | 1 |
| Liu, S | 1 |
| Shepherd, LE | 2 |
| Palmer, M | 1 |
| Robert, NJ | 1 |
| Martino, S | 1 |
| Muss, HB | 1 |
| Moy, B | 1 |
| Pans, S | 1 |
| Westhovens, R | 1 |
| Verhaeghe, J | 1 |
| Wildiers, H | 1 |
| Leunen, K | 1 |
| Amant, F | 1 |
| Berteloot, P | 1 |
| Smeets, A | 1 |
| Weltens, C | 1 |
| Van den Bogaert, W | 1 |
| De Smet, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase III Randomized Double Blind Study of Letrozole Versus Placebo in Women With Primary Breast Cancer Completing Five or More Years of Adjuvant Tamoxifen[NCT00003140] | Phase 3 | 5,187 participants (Actual) | Interventional | 1998-08-24 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for letrozole and Ache
| Article | Year |
|---|---|
Letrozole combined with oral contraceptives versus oral contraceptives alone in the treatment of endometriosis-related pain symptoms: a pilot study.
Topics: Adult; Aromatase Inhibitors; Contraceptives, Oral, Hormonal; Desogestrel; Drug Therapy, Combination; | 2021 |
Acute effects of tamoxifen and third-generation aromatase inhibitors on menopausal symptoms of breast cancer patients.
Topics: Anastrozole; Aromatase Inhibitors; Belgium; Body Mass Index; Breast Neoplasms; Data Interpretation, | 2004 |
Assessment of quality of life in MA.17: a randomized, placebo-controlled trial of letrozole after 5 years of tamoxifen in postmenopausal women.
Topics: Administration, Oral; Aged; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; | 2005 |
Clinical outcomes of ethnic minority women in MA.17: a trial of letrozole after 5 years of tamoxifen in postmenopausal women with early stage breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherap | 2006 |
6 other studies available for letrozole and Ache
| Article | Year |
|---|---|
Steroidal and non-steroidal third-generation aromatase inhibitors induce pain-like symptoms via TRPA1.
Topics: Anastrozole; Androstadienes; Animals; Aromatase Inhibitors; Behavior, Animal; Calcium; Calcium Chann | 2014 |
Colocalization of aromatase in spinal cord astrocytes: differences in expression and relationship to mechanical and thermal hyperalgesia in murine models of a painful and a non-painful bone tumor.
Topics: Analysis of Variance; Animals; Antineoplastic Agents; Aromatase; Bone Neoplasms; Cell Line, Tumor; D | 2015 |
Sciatic nerve injury induces apoptosis of dorsal root ganglion satellite glial cells and selectively modifies neurosteroidogenesis in sensory neurons.
Topics: Animals; Apoptosis; Aromatase; Aromatase Inhibitors; Cell Survival; Estradiol; Ganglia, Spinal; Letr | 2010 |
Aromatase inhibitors in the treatment of bladder endometriosis.
Topics: Adult; Aromatase Inhibitors; Calcium; Cholecalciferol; Cystectomy; Drug Therapy, Combination; Endome | 2011 |
Increase in formalin-induced tonic pain by 5alpha-reductase and aromatase inhibition in female rats.
Topics: 5-alpha Reductase Inhibitors; Analgesics, Opioid; Animals; Aromatase Inhibitors; Drug Synergism; Fem | 2011 |
Debilitating musculoskeletal pain and stiffness with letrozole and exemestane: associated tenosynovial changes on magnetic resonance imaging.
Topics: Aged; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Carpal Tunnel Syndrome; Female; Humans | 2007 |