Page last updated: 2024-09-03

lestaurtinib and Prostatic Neoplasms

lestaurtinib has been researched along with Prostatic Neoplasms in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's6 (66.67)29.6817
2010's2 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Attwood, K; Azabdaftari, G; Ben-Salem, S; Cortes, E; Dehm, SM; DePriest, AD; Heemers, HV; Hu, Q; Jamieson, C; Klein, E; Kumari, S; Liu, S; Magi-Galluzzi, C; Mohler, JL; Mudduluru, G; Pop, E; Senapati, D; Shah, RB; Sharifi, N; Su, Y; Venkadakrishnan, VB1
Bologna, M; Dolo, V; Festuccia, C; Ficorella, C; Gravina, GL; Millimaggi, D; Muzi, P; Ricevuto, E; Vicentini, C1
Eberlin, A; Erlenkamp, G; Jung, M; Köhler, J; Metzger, E; Rumpf, T; Schüle, R; Sippl, W; Slynko, I1
Beckhardt, S1
Bologna, M; Dolo, V; Festuccia, C; Gravina, GL; Millimaggi, D; Muzi, P; Ricevuto, E; Speca, S; Vicentini, C1
Bologna, M; Festuccia, C; Gravina, GL; Muzi, P; Pomante, R; Ricevuto, E; Ventura, L; Vicentini, C1
Carducci, MA; Collins, C; Denmeade, SR; Eisenberger, MA; Isaacs, JT; Partin, AW; Pili, R; Sinibaldi, VJ; Walczak, JS1
Angeles, T; Dionne, CA; George, DJ; Isaacs, JT; Jani, J; Lamb, J; Murakata, C1
Dalrymple, SL; Denmeade, SR; Dionne, CA; Isaacs, JT; Lamb, JC; Miknyoczki, S; Weeraratna, AT1

Other Studies

9 other study(ies) available for lestaurtinib and Prostatic Neoplasms

ArticleYear
Protein Kinase N1 control of androgen-responsive serum response factor action provides rationale for novel prostate cancer treatment strategy.
    Oncogene, 2019, Volume: 38, Issue:23

    Topics: Androgens; Animals; Carbazoles; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Progression; Furans; Humans; Male; Mice; Mice, Nude; Neoplasm Transplantation; Prostatic Neoplasms; Protein Kinase C; Sequence Analysis, RNA; Serum Response Factor; Transcription Factors

2019
Her2 crosstalks with TrkA in a subset of prostate cancer cells: rationale for a guided dual treatment.
    The Prostate, 2009, Mar-01, Volume: 69, Issue:4

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Carbazoles; Cell Line, Tumor; Cell Proliferation; Drug Therapy, Combination; Furans; Male; Mice; Nerve Growth Factor; Prostatic Neoplasms; Receptor Cross-Talk; Receptor, ErbB-2; Receptor, trkA; Receptors, Androgen; Xenograft Model Antitumor Assays

2009
Lestaurtinib inhibits histone phosphorylation and androgen-dependent gene expression in prostate cancer cells.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: Androgens; Carbazoles; Cell Line, Tumor; Cells, Cultured; Enzyme Inhibitors; Furans; Gene Expression; Histones; Humans; Male; Phosphorylation; Prostatic Neoplasms; Protein Kinase C; Receptors, Androgen

2012
Re: growth factor receptor tyrosine kinase inhibitors; clinical development and potential for prostate cancer therapy.
    The Journal of urology, 2004, Volume: 172, Issue:4 Pt 1

    Topics: Carbazoles; Clinical Trials, Phase II as Topic; Enzyme Inhibitors; Furans; Humans; Indoles; Male; Prodrugs; Prostatic Neoplasms; Protein-Tyrosine Kinases

2004
Tyrosine kinase inhibitor CEP-701 blocks the NTRK1/NGF receptor and limits the invasive capability of prostate cancer cells in vitro.
    International journal of oncology, 2007, Volume: 30, Issue:1

    Topics: Brain-Derived Neurotrophic Factor; Carbazoles; Cell Line, Tumor; Enzyme Inhibitors; Furans; Humans; Indoles; Male; Neoplasm Invasiveness; Nerve Growth Factors; Prostatic Neoplasms; Protein-Tyrosine Kinases; Receptor, trkA; Receptors, Androgen

2007
In vitro and in vivo effects of bicalutamide on the expression of TrkA and P75 neurotrophin receptors in prostate carcinoma.
    The Prostate, 2007, Sep-01, Volume: 67, Issue:12

    Topics: Adult; Aged; Androgen Antagonists; Anilides; Antineoplastic Agents; Blotting, Western; Carbazoles; Carcinoma; Cell Line, Tumor; Cohort Studies; Dihydrotestosterone; Furans; Humans; Immunohistochemistry; Indoles; Male; Middle Aged; Neoadjuvant Therapy; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; Protein Kinase Inhibitors; Receptor, Nerve Growth Factor; Receptor, trkA; Receptor, trkC; Tosyl Compounds

2007
Preclinical and clinical studies with the multi-kinase inhibitor CEP-701 as treatment for prostate cancer demonstrate the inadequacy of PSA response as a primary endpoint.
    Cancer biology & therapy, 2007, Volume: 6, Issue:9

    Topics: 3T3 Cells; Aged; Aged, 80 and over; Animals; Carbazoles; Cell Line, Tumor; Drug Screening Assays, Antitumor; Furans; Humans; Indoles; Male; Mice; Mice, Nude; Middle Aged; Neoplasm Metastasis; Neoplasm Transplantation; Prostate-Specific Antigen; Prostatic Neoplasms; Protein Kinase Inhibitors

2007
Sustained in vivo regression of Dunning H rat prostate cancers treated with combinations of androgen ablation and Trk tyrosine kinase inhibitors, CEP-751 (KT-6587) or CEP-701 (KT-5555).
    Cancer research, 1999, May-15, Volume: 59, Issue:10

    Topics: Adenocarcinoma; Administration, Oral; Androgens; Animals; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Carbazoles; Combined Modality Therapy; Drug Screening Assays, Antitumor; Drug Synergism; Furans; Indoles; Injections, Subcutaneous; Leuprolide; Male; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Orchiectomy; Prostatic Neoplasms; Proto-Oncogene Proteins; Rats; Receptor Protein-Tyrosine Kinases; Receptor, trkA; Receptors, Nerve Growth Factor

1999
Pan-trk inhibition decreases metastasis and enhances host survival in experimental models as a result of its selective induction of apoptosis of prostate cancer cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:8

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Apoptosis; Carbazoles; Cell Division; Cell Line; Disease Models, Animal; Furans; Humans; Indoles; Male; Mice; Mice, Nude; Neoplasm Metastasis; Prostate-Specific Antigen; Prostatic Neoplasms; Rats; Receptor, trkA; Survival Analysis; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2001