Page last updated: 2024-09-03

lestaurtinib and Acute Lymphoid Leukemia

lestaurtinib has been researched along with Acute Lymphoid Leukemia in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's1 (20.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Borowitz, MJ; Brown, PA; Carroll, AJ; Carroll, WL; Devidas, M; Dreyer, ZE; Gore, L; Heerema, NA; Hilden, JM; Hunger, SP; Kairalla, JA; Loh, ML; Raetz, EA; Salzer, WL; Small, D; Wang, C; Winick, NJ1
Breen, M; Richards, KL; Seiser, EL; Small, GW; Suter, SE; Thomas, R1
Brown, P; Campana, D; Downing, J; Levis, M; Shurtleff, S; Small, D1
Zhang, GS1
Brown, P; Griesemer, M; Levis, M; McIntyre, E; Small, D1

Trials

1 trial(s) available for lestaurtinib and Acute Lymphoid Leukemia

ArticleYear
FLT3 inhibitor lestaurtinib plus chemotherapy for newly diagnosed KMT2A-rearranged infant acute lymphoblastic leukemia: Children's Oncology Group trial AALL0631.
    Leukemia, 2021, Volume: 35, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carbazoles; Female; fms-Like Tyrosine Kinase 3; Furans; Histone-Lysine N-Methyltransferase; Humans; Infant; Male; Myeloid-Lymphoid Leukemia Protein; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase Inhibitors

2021

Other Studies

4 other study(ies) available for lestaurtinib and Acute Lymphoid Leukemia

ArticleYear
FLT3 mutations in canine acute lymphocytic leukemia.
    BMC cancer, 2011, Jan-27, Volume: 11

    Topics: Amino Acid Sequence; Animals; Blotting, Western; Carbazoles; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; DNA Mutational Analysis; DNA, Neoplasm; Dogs; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; fms-Like Tyrosine Kinase 3; Furans; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Molecular Sequence Data; Mutation; Phosphorylation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Reverse Transcriptase Polymerase Chain Reaction; STAT5 Transcription Factor

2011
FLT3 inhibition selectively kills childhood acute lymphoblastic leukemia cells with high levels of FLT3 expression.
    Blood, 2005, Jan-15, Volume: 105, Issue:2

    Topics: Age Factors; Apoptosis; Carbazoles; Child; DNA-Binding Proteins; Enzyme Inhibitors; fms-Like Tyrosine Kinase 3; Furans; Gene Expression Regulation, Leukemic; Gene Rearrangement; Genotype; Histone-Lysine N-Methyltransferase; Humans; Indoles; Infant; Myeloid-Lymphoid Leukemia Protein; Phenotype; Ploidies; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogene Proteins; Proto-Oncogenes; Receptor Protein-Tyrosine Kinases; Transcription Factors; Tumor Cells, Cultured

2005
[New targets for molecular therapy of acute leukemia: a "single-hit" or "multiple-hit" strategy against signaling pathway].
    Zhonghua yi xue za zhi, 2005, Feb-23, Volume: 85, Issue:7

    Topics: Acute Disease; Antineoplastic Agents; Carbazoles; Furans; Humans; Indoles; Leukemia; Leukemia, Myeloid, Acute; Mutation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein-Tyrosine Kinases; Quinolones; ras Proteins; Staurosporine

2005
Combinations of the FLT3 inhibitor CEP-701 and chemotherapy synergistically kill infant and childhood MLL-rearranged ALL cells in a sequence-dependent manner.
    Leukemia, 2006, Volume: 20, Issue:8

    Topics: Antineoplastic Agents; Carbazoles; Cell Line, Tumor; Child; Dose-Response Relationship, Drug; Drug Synergism; fms-Like Tyrosine Kinase 3; Furans; G1 Phase; Gene Rearrangement; Histone-Lysine N-Methyltransferase; Humans; Indoles; Infant; Myeloid-Lymphoid Leukemia Protein; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase Inhibitors

2006