lepadiformine and Leukemia-P388

lepadiformine has been researched along with Leukemia-P388* in 1 studies

Other Studies

1 other study(ies) available for lepadiformine and Leukemia-P388

Article	Year
Total Syntheses of Lepadiformine Marine Alkaloids with Enantiodivergency, Utilizing Hg(OTf) Chemistry (Weinheim an der Bergstrasse, Germany), 2017, Jul-18, Volume: 23, Issue:40 The enantioselective total syntheses of lepadiformine marine alkaloids, azatricyclic natural products isolated from marine tunicates, were completed. These alkaloids have a unique chemical structure characterized by the trans-1-azadecalin (AB ring system) fused with the spirocyclic ring (AC ring system). Here we found that a cycloisomerization reaction from functionalized linear substrates to a 1-azaspiro[4.5]decane framework corresponding to the AC ring in lepadiformines is promoted by a catalytic amount of mercury(II) triflate (Hg(OTf) Topics: Alkaloids; Animals; Antineoplastic Agents; Aquatic Organisms; Catalysis; Cell Proliferation; Cell Survival; HeLa Cells; HT29 Cells; Humans; Leukemia P388; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Stereoisomerism; Urochordata	2017

Article

Year

Total Syntheses of Lepadiformine Marine Alkaloids with Enantiodivergency, Utilizing Hg(OTf)

Chemistry (Weinheim an der Bergstrasse, Germany), 2017, Jul-18, Volume: 23, Issue:40

The enantioselective total syntheses of lepadiformine marine alkaloids, azatricyclic natural products isolated from marine tunicates, were completed. These alkaloids have a unique chemical structure characterized by the trans-1-azadecalin (AB ring system) fused with the spirocyclic ring (AC ring system). Here we found that a cycloisomerization reaction from functionalized linear substrates to a 1-azaspiro[4.5]decane framework corresponding to the AC ring in lepadiformines is promoted by a catalytic amount of mercury(II) triflate (Hg(OTf)

Topics: Alkaloids; Animals; Antineoplastic Agents; Aquatic Organisms; Catalysis; Cell Proliferation; Cell Survival; HeLa Cells; HT29 Cells; Humans; Leukemia P388; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Stereoisomerism; Urochordata

2017