Compounds > leonurine
Page last updated: 2024-09-04

leonurine and Osteoarthritis

leonurine has been researched along with Osteoarthritis in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Hu, PF; Qian, J; Sun, FF1
Chen, C; Hu, N; Huang, W; Liang, X; Zhu, Z1
Lei, Y; Yin, W1
Feng, ZH; Fu, X; Gong, LF; Hu, ZC; Li, XB; Ni, WF; Xuan, JW1

Other Studies

4 other study(ies) available for leonurine and Osteoarthritis

ArticleYear
Leonurine Exerts Anti-Catabolic and Anti-Apoptotic Effects via Nuclear Factor kappa B (NF-κB) and Mitogen-Activated Protein Kinase (MAPK) Signaling Pathways in Chondrocytes.
    Medical science monitor : international medical journal of experimental and clinical research, 2019, Aug-21, Volume: 25

    Topics: ADAM Proteins; Animals; Apoptosis; Cells, Cultured; Chondrocytes; Gallic Acid; Interleukin-1beta; Male; MAP Kinase Signaling System; Matrix Metalloproteinases; Mitogen-Activated Protein Kinases; NF-kappa B; Osteoarthritis; Phosphorylation; Rats; Rats, Sprague-Dawley; Signal Transduction

2019
Leonurine Hydrochloride Suppresses Inflammatory Responses and Ameliorates Cartilage Degradation in Osteoarthritis via NF-κB Signaling Pathway.
    Inflammation, 2020, Volume: 43, Issue:1

    Topics: ADAMTS5 Protein; Animals; Anterior Cruciate Ligament; Anti-Inflammatory Agents; Cartilage Diseases; Cartilage, Articular; Cell Line; Chondrocytes; Gallic Acid; Inflammation; Interleukin-6; Male; Matrix Metalloproteinase 1; Matrix Metalloproteinase 13; Matrix Metalloproteinase 3; NF-kappa B; Osteoarthritis; Rats

2020
Leonurine inhibits IL-1β induced inflammation in murine chondrocytes and ameliorates murine osteoarthritis.
    International immunopharmacology, 2018, Volume: 65

    Topics: Animals; Chondrocytes; Disease Models, Animal; Gallic Acid; Gene Expression Regulation; Interleukin-1beta; Male; Mice; Mice, Inbred C57BL; Osteoarthritis

2018
Inhibition of PI3K/Akt/NF-κB signaling with leonurine for ameliorating the progression of osteoarthritis: In vitro and in vivo studies.
    Journal of cellular physiology, 2019, Volume: 234, Issue:5

    Topics: Animals; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Down-Regulation; Extracellular Matrix; Gallic Acid; Humans; Interleukin-1beta; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Molecular Docking Simulation; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Osteoarthritis; Phosphatidylinositol 3-Kinases; Protective Agents; Proto-Oncogene Proteins c-akt; Signal Transduction

2019