Page last updated: 2024-09-04

leonurine and Disease Models, Animal

leonurine has been researched along with Disease Models, Animal in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's12 (70.59)24.3611
2020's5 (29.41)2.80

Authors

AuthorsStudies
Chen, XJ; Luo, YJ; Qiu, LN; Tan, YR1
Chen, X; Pan, Y; Qi, L; Shi, C; Tang, M; Wang, H; Yang, B; Zha, Z1
Bai, D; Hao, J; Li, H; Li, Q; Liang, Y; Sun, Y; Xu, X1
Ge, J; Li, D; Li, P; Lin, X; Meng, P; Wang, X; Wang, Y; Yang, H; Zhang, X; Zhao, H1
Li, D; Li, G; Lv, D; Ouyang, J; Peng, L; Shang, F; Wang, R; Yan, J; Yang, J1
Chen, M; Ding, J; Ding, X; Du, R; Hu, G; Jia, M; Li, C; Lu, M; Zheng, Y1
Feng, Y; Jin, H; Lou, Y; Mao, C; Wang, C; Wang, Q; Xu, H; Xu, T; Zhang, L; Zhang, Z1
Jiang, X; Wei, F; Xu, L; Zhu, H1
Chen, X; Dai, A; Deng, G; Huang, C; Jiang, K; Li, X; Wu, H; Yang, X1
Lei, Y; Yin, W1
Cao, W; Chen, Z; Huang, Z; Li, Q; Liu, X; Qi, J; Wu, L; Xing, C; Yuan, Y; Zhang, B; Zhao, M; Zhu, J1
Gu, Y; Huang, J; Huang, R; Jin, M; Li, Q; Wan, B; Xu, X; Zhang, Y1
He, XL; Jiang, DL; Jin, C; Li, X; Su, Q; Xu, RS; Yuan, FL1
Bo, Y; Cheng, H; Jia, Z; Li, F; Shen, W; Tan, J; Xu, C1
Gao, J; Liu, C; Xu, X; Yang, Z; Yin, H; Zhang, T1
Hong, ZY; Qi, J; Xin, H; Zhu, YZ1
Cao, X; Dong, L; Du, Y; Ji, H; Ji, Y; Li, L; Li, S; Liu, H; Wang, C; Xing, Y; Zhang, X; Zhao, K1

Other Studies

17 other study(ies) available for leonurine and Disease Models, Animal

ArticleYear
Leonurine protects against influenza A virus infection-induced pneumonia in mice.
    Pathogens and disease, 2021, 09-23, Volume: 79, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Gallic Acid; Gene Expression Regulation; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Lung Injury; Mice; Mice, Inbred BALB C; NF-kappa B; Orthomyxoviridae Infections; Pneumonia; Signal Transduction; Specific Pathogen-Free Organisms; Swine; Toll-Like Receptor 4

2021
Leonurine exerts a protective effect in dextran sodium sulfate-induced experimental inflammatory bowel disease mice model.
    General physiology and biophysics, 2022, Volume: 41, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Dextran Sulfate; Disease Models, Animal; Gallic Acid; Inflammatory Bowel Diseases; Mice; Mice, Inbred C57BL; NF-kappa B; Sulfates

2022
Leonurine attenuates OVA-induced asthma via p38 MAPK/NF-κB signaling pathway.
    International immunopharmacology, 2023, Volume: 114

    Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Molecular Docking Simulation; NF-kappa B; Ovalbumin; p38 Mitogen-Activated Protein Kinases; Signal Transduction

2023
Leonurine Regulates Hippocampal Nerve Regeneration in Rats with Chronic and Unpredictable Mild Stress by Activating SHH/GLI Signaling Pathway and Restoring Gut Microbiota and Microbial Metabolic Homeostasis.
    Neural plasticity, 2023, Volume: 2023

    Topics: Animals; Body Weight; Brain-Derived Neurotrophic Factor; Bromodeoxyuridine; Depression; Disease Models, Animal; Gastrointestinal Microbiome; Hippocampus; Homeostasis; Nerve Regeneration; Rats; Serotonin; Signal Transduction; Stress, Psychological

2023
Leonurine Attenuates Myocardial Fibrosis Through Upregulation of miR-29a-3p in Mice Post-myocardial Infarction.
    Journal of cardiovascular pharmacology, 2021, 02-01, Volume: 77, Issue:2

    Topics: Angiotensin II; Animals; Cell Movement; Cell Proliferation; Cells, Cultured; Collagen; Disease Models, Animal; Fibroblasts; Fibrosis; Gallic Acid; Male; Mice, Inbred C57BL; MicroRNAs; Myocardial Infarction; Myocardium; Transforming Growth Factor beta; Up-Regulation; Ventricular Function, Left; Ventricular Remodeling

2021
Leonurine Exerts Antidepressant-Like Effects in the Chronic Mild Stress-Induced Depression Model in Mice by Inhibiting Neuroinflammation.
    The international journal of neuropsychopharmacology, 2017, 11-01, Volume: 20, Issue:11

    Topics: Animals; Antidepressive Agents; Calcium-Binding Proteins; Cytokines; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Encephalitis; Fluoxetine; Food Preferences; Gallic Acid; Male; Mice; Mice, Inbred C57BL; Microfilament Proteins; Microglia; Neurons; Neurotransmitter Agents; Prefrontal Cortex; Stress, Psychological; Swimming

2017
Upregulating mTOR/ERK signaling with leonurine for promoting angiogenesis and tissue regeneration in a full-thickness cutaneous wound model.
    Food & function, 2018, Apr-25, Volume: 9, Issue:4

    Topics: Angiogenesis Inducing Agents; Animals; Cell Movement; Disease Models, Animal; Drugs, Chinese Herbal; Extracellular Signal-Regulated MAP Kinases; Gallic Acid; Human Umbilical Vein Endothelial Cells; Humans; Neovascularization, Pathologic; Rats; Regeneration; Signal Transduction; Skin; TOR Serine-Threonine Kinases; Wound Healing; Wounds and Injuries

2018
Leonurine protects cardiac function following acute myocardial infarction through anti‑apoptosis by the PI3K/AKT/GSK3β signaling pathway.
    Molecular medicine reports, 2018, Volume: 18, Issue:2

    Topics: Administration, Oral; Animals; Apoptosis; bcl-2-Associated X Protein; Cardiotonic Agents; Cerebrovascular Disorders; Coronary Vessels; Disease Models, Animal; Drug Administration Schedule; Echocardiography; Gallic Acid; Gene Expression Regulation; Glycogen Synthase Kinase 3 beta; Male; Myocardial Infarction; Myocytes, Cardiac; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Signal Transduction

2018
Leonurine ameliorates the inflammatory responses in lipopolysaccharide-induced endometritis.
    International immunopharmacology, 2018, Volume: 61

    Topics: Animals; Anti-Inflammatory Agents; Cattle; Cells, Cultured; Disease Models, Animal; Endometritis; Endometrium; Epithelial Cells; Female; Gallic Acid; Interleukin-1beta; Leonurus; Lipopolysaccharides; Mice; NF-kappa B; Signal Transduction; Tumor Necrosis Factor-alpha

2018
Leonurine inhibits IL-1β induced inflammation in murine chondrocytes and ameliorates murine osteoarthritis.
    International immunopharmacology, 2018, Volume: 65

    Topics: Animals; Chondrocytes; Disease Models, Animal; Gallic Acid; Gene Expression Regulation; Interleukin-1beta; Male; Mice; Mice, Inbred C57BL; Osteoarthritis

2018
Leonurine ameliorates adriamycin-induced podocyte injury via suppression of oxidative stress.
    Free radical research, 2018, Volume: 52, Issue:9

    Topics: Animals; Apoptosis; Disease Models, Animal; Doxorubicin; Gallic Acid; Humans; Kidney; Kidney Diseases; Macrophages; Mice; Oxidative Stress; Podocytes; Proteinuria; Reactive Oxygen Species; Wounds and Injuries

2018
Leonurine suppresses neuroinflammation through promoting oligodendrocyte maturation.
    Journal of cellular and molecular medicine, 2019, Volume: 23, Issue:2

    Topics: Animals; Cell Differentiation; Central Nervous System; Cuprizone; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Gallic Acid; Humans; Inflammation; Jumonji Domain-Containing Histone Demethylases; Mice; Microglia; Multiple Sclerosis; Myelin Sheath; Neurogenesis; Oligodendroglia; Remyelination

2019
Leonurine hydrochloride inhibits osteoclastogenesis and prevents osteoporosis associated with estrogen deficiency by inhibiting the NF-κB and PI3K/Akt signaling pathways.
    Bone, 2015, Volume: 75

    Topics: Animals; Blotting, Western; Cell Differentiation; Cells, Cultured; Disease Models, Animal; Electrophoretic Mobility Shift Assay; Female; Fluorescent Antibody Technique; Gallic Acid; Humans; Mice; Mice, Inbred BALB C; NF-kappa B; Osteoclasts; Osteoporosis, Postmenopausal; Ovariectomy; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction

2015
Leonurine ameliorates kidney fibrosis via suppressing TGF-β and NF-κB signaling pathway in UUO mice.
    International immunopharmacology, 2015, Volume: 25, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Epithelial-Mesenchymal Transition; Fibrosis; Gallic Acid; Kidney; Kidney Diseases; Mice, Inbred C57BL; NF-kappa B; Protective Agents; Reactive Oxygen Species; Signal Transduction; Transforming Growth Factor beta; Urethral Obstruction

2015
Leonurine ameliorates cognitive dysfunction via antagonizing excitotoxic glutamate insults and inhibiting autophagy.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2016, Dec-01, Volume: 23, Issue:13

    Topics: Animals; Autophagy; Brain; Cognitive Dysfunction; Disease Models, Animal; Excitatory Postsynaptic Potentials; Gallic Acid; Glutamates; Hippocampus; Neuroprotective Agents; Pyramidal Cells; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spatial Memory

2016
Neuroprotective effects of leonurine on ischemia/reperfusion-induced mitochondrial dysfunctions in rat cerebral cortex.
    Biological & pharmaceutical bulletin, 2010, Volume: 33, Issue:12

    Topics: Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Brain Ischemia; Cerebral Cortex; Cerebral Infarction; Cytochromes c; Disease Models, Animal; Drugs, Chinese Herbal; Gallic Acid; In Situ Nick-End Labeling; Leonurus; Male; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Membranes; Neuroprotective Agents; Oxidative Stress; Phytotherapy; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury

2010
Leonurine protects brain injury by increased activities of UCP4, SOD, CAT and Bcl-2, decreased levels of MDA and Bax, and ameliorated ultrastructure of mitochondria in experimental stroke.
    Brain research, 2012, Sep-20, Volume: 1474

    Topics: Animals; bcl-2-Associated X Protein; Blotting, Western; Brain Injuries; Catalase; Disease Models, Animal; Gallic Acid; Immunohistochemistry; Ion Channels; Male; Malondialdehyde; Microscopy, Electron, Transmission; Mitochondria; Mitochondrial Proteins; Mitochondrial Uncoupling Proteins; Neuroprotective Agents; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Stroke; Superoxide Dismutase

2012