lenvatinib has been researched along with Rupture* in 2 studies
2 other study(ies) available for lenvatinib and Rupture
| Article | Year |
|---|---|
Two Cases of Intraabdominal Bleeding Caused by Hepatocellular Carcinoma Rupture Soon after the Initiation of Chemotherapy with Lenvatinib.
We herein report two patients with hepatocellular carcinoma (HCC) who exhibited intraabdominal bleeding caused by tumor rupture soon after lenvatinib initiation. A hypervascular nodule was present in the lateral segment manifesting extrahepatic protrusion in an 81-year-old-man and in the caudate lobe, which was completely occupied by the tumor, in an 83-year-old-man. Both patients were given lenvatinib, and epigastralgia occurred suddenly three and five days later. Computed tomography revealed high-attenuation areas suggesting bleeding around the left and caudate lobes. Considering the strong antiangiogenic effects by lenvatinib, transcatheter arterial embolization should be performed before lenvatinib initiation in patients with subcapsular HCC. Topics: Aged, 80 and over; Carcinoma, Hepatocellular; Hemoperitoneum; Humans; Liver Neoplasms; Phenylurea Compounds; Quinolines; Rupture | 2022 |
[A Case of a Rupture of the Carotid Artery Caused by the Lenvatinib Medication].
We report a case of a rupture of the common carotid artery caused by the medication of lenvatinib. The patient, 70-yearold female, was referred to our hospital by unresectable papillary thyroid cancer infiltrated the left common carotid artery. Externalbeam radiotherapy and radioiodine therapy were undergone after totalthyroidectomy. After 1 year 7 months from operation, she admitted our hospital due to left shoulder pain and dysphagia caused by the growing left cervical tumor. The medication of lenvatinib was decided after the careful informed consent. Computed tomography on the eighth day of lenvatinib medication showed the existence of air infiltration into the tumor surrounded left common carotid artery. So, a discontinuance of lenvatinib medication was decided immediately. But, on the ninth day, a rupture of the left common carotid artery occurred and on the tenth day, she died. Lenvatinib medication for the patient with the tumor surrounded artery should be decided carefully. Topics: Aged; Antineoplastic Agents; Carcinoma, Papillary; Carotid Artery Diseases; Fatal Outcome; Female; Humans; Phenylurea Compounds; Quinolines; Rupture; Thyroid Cancer, Papillary; Thyroid Neoplasms | 2017 |