Page last updated: 2024-09-05

lenalidomide and Colorectal Cancer

lenalidomide has been researched along with Colorectal Cancer in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's7 (77.78)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Huang, Y; Wu, L; Yin, D1
Beck, R; Bencardino, K; Elez, ME; Gandhi, A; Jungnelius, U; Li, M; Prenen, H; Romano, A; Sanchis, M; Sartore-Bianchi, A; Shi, T; Siena, S; Tabernero, J; Tejpar, S; Van Cutsem, E1
Chopra, R; Gandhi, AK; Jungnelius, U; Li, M; Romano, A; Schafer, PH; Shi, T; Siena, S; Tabernero, J1
Amann, A; Auer, T; Gamerith, G; Hilbe, W; Kircher, B; Loeffler-Ragg, J; Putzer, D; Schenk, B; Zwierzina, H1
Falchook, G; Fu, S; Hong, DS; Janku, F; Kakadiaris, E; Kurzrock, R; Piha-Paul, S; Said, R; Tsimberidou, AM; Wheler, JJ; Zinner, R1
Aglietta, M; Bertotti, A; Bussolino, F; Gammaitoni, L; Giraudo, E; Giraudo, L; Grignani, G; Leone, F; Leuci, V; Luraghi, P; Maione, F; Mesiano, G; Migliardi, G; Rotolo, R; Sangiolo, D; Sassi, F; Todorovic, M; Trusolino, L1
Bertino, EM; Carson, WE; Davis, M; Grever, M; McMichael, EL; Mo, X; Otterson, GA; Paul, B; Trikha, P1
Bolton, TB; Dalgleish, AG; Galustian, C; Henry, JY; Laux, H; Liu, WM1
Bartlett, JB; Dalgleish, AG; Galustian, C; Henry, JY; Liu, WM; Meyer, B1

Trials

4 trial(s) available for lenalidomide and Colorectal Cancer

ArticleYear
Phase II open-label study to assess efficacy and safety of lenalidomide in combination with cetuximab in KRAS-mutant metastatic colorectal cancer.
    PloS one, 2013, Volume: 8, Issue:11

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cetuximab; Colorectal Neoplasms; Female; Humans; Lenalidomide; Male; Maximum Tolerated Dose; Middle Aged; Mutation; Neoplasm Metastasis; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Thalidomide; Time Factors

2013
Immunomodulatory effects in a phase II study of lenalidomide combined with cetuximab in refractory KRAS-mutant metastatic colorectal cancer patients.
    PloS one, 2013, Volume: 8, Issue:11

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cetuximab; Colorectal Neoplasms; Humans; Lenalidomide; Mutation; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Thalidomide

2013
Phase I clinical trial of lenalidomide in combination with bevacizumab in patients with advanced cancer.
    Cancer chemotherapy and pharmacology, 2016, Volume: 77, Issue:5

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Colorectal Neoplasms; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Injections, Intravenous; Lenalidomide; Male; Maximum Tolerated Dose; Melanoma; Middle Aged; Response Evaluation Criteria in Solid Tumors; Thalidomide

2016
A Phase I Trial to Evaluate Antibody-Dependent Cellular Cytotoxicity of Cetuximab and Lenalidomide in Advanced Colorectal and Head and Neck Cancer.
    Molecular cancer therapeutics, 2016, Volume: 15, Issue:9

    Topics: Adult; Aged; Antibody-Dependent Cell Cytotoxicity; Antineoplastic Combined Chemotherapy Protocols; Cetuximab; Colorectal Neoplasms; Cytokines; Female; Head and Neck Neoplasms; Humans; Lenalidomide; Male; Middle Aged; Neoplasm Staging; Retreatment; T-Lymphocyte Subsets; Thalidomide; Treatment Outcome

2016

Other Studies

5 other study(ies) available for lenalidomide and Colorectal Cancer

ArticleYear
Identification of cuproptosis-related subtypes and development of a prognostic signature in colorectal cancer.
    Scientific reports, 2022, 10-17, Volume: 12, Issue:1

    Topics: Apoptosis; Colorectal Neoplasms; Copper; Doxorubicin; Gene Expression Regulation, Neoplastic; Humans; Lenalidomide; Prognosis; Proto-Oncogene Proteins c-akt; Tumor Microenvironment

2022
Increase in antibody-dependent cellular cytotoxicity (ADCC) in a patient with advanced colorectal carcinoma carrying a KRAS mutation under lenalidomide therapy.
    Cancer biology & therapy, 2014, Mar-01, Volume: 15, Issue:3

    Topics: Adenomatous Polyposis Coli; Adult; Angiogenesis Inhibitors; Antibody-Dependent Cell Cytotoxicity; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Humans; Killer Cells, Natural; Lenalidomide; Liver Neoplasms; Lung Neoplasms; Mutation; Pelvic Neoplasms; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Thalidomide

2014
Lenalidomide normalizes tumor vessels in colorectal cancer improving chemotherapy activity.
    Journal of translational medicine, 2016, 05-05, Volume: 14, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Fluorouracil; Humans; Lenalidomide; Mice; Mice, SCID; Neoplasm Metastasis; Neovascularization, Pathologic; Perfusion; Pericytes; Thalidomide; Tumor Hypoxia; Xenograft Model Antitumor Assays

2016
A microarray study of altered gene expression in colorectal cancer cells after treatment with immunomodulatory drugs: differences in action in vivo and in vitro.
    Molecular biology reports, 2010, Volume: 37, Issue:4

    Topics: Animals; Biomarkers; Blotting, Western; Cell Line, Tumor; Cluster Analysis; Colorectal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Genes, Neoplasm; Immunologic Factors; Lenalidomide; Lymphocytes; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Oligonucleotide Array Sequence Analysis; Quality Control; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; Thalidomide

2010
Inhibition of metastatic potential in colorectal carcinoma in vivo and in vitro using immunomodulatory drugs (IMiDs).
    British journal of cancer, 2009, Sep-01, Volume: 101, Issue:5

    Topics: Animals; Antineoplastic Agents; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Immunoblotting; Immunohistochemistry; Immunologic Factors; Lenalidomide; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neoplasm Invasiveness; Neoplasm Metastasis; Signal Transduction; Thalidomide; Tumor Cells, Cultured

2009