Page last updated: 2024-09-05

lenalidomide and Chromosomal Translocation

lenalidomide has been researched along with Chromosomal Translocation in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (5.00)29.6817
2010's15 (75.00)24.3611
2020's4 (20.00)2.80

Authors

AuthorsStudies
Bashir, Q; Bassett, R; Champlin, RE; Gaballa, MR; Kaufman, GP; Kebriaei, P; Lee, HC; Lin, P; Ma, J; Manasanch, EE; Murphy, R; Nieto, Y; Orlowski, RZ; Pasvolsky, O; Patel, KK; Qazilbash, MH; Ramdial, J; Rauf, M; Rezvani, K; Saini, N; Shpall, EJ; Srour, SA; Tang, G; Tanner, MR; Thomas, SK; Ullah, MR; Weber, DM1
Bashir, Q; Champlin, RE; Gaballa, MR; Kebriaei, P; Lee, HC; Lin, P; Masood, A; Milton, DR; Nieto, Y; Orlowski, RZ; Pasvolsky, O; Patel, KK; Qazilbash, MH; Ramdial, J; Saini, N; Sami, SS; Shpall, EJ; Srour, S; Tang, G; Tanner, MR; Thomas, SK; Weber, DM1
Avet-Loiseau, H; Bahlis, NJ; Benboubker, L; Casneuf, T; Chari, A; Cochrane, T; Cook, G; Dimopoulos, MA; Iida, S; Joy Ho, P; Kaufman, JL; Kim, JS; Kim, K; Kobos, R; Krevvata, M; Leiba, M; Magen, H; Miles Prince, H; Moreau, P; Morton, J; O'Rourke, L; Oriol, A; San-Miguel, J; Sutherland, HJ; Takezako, N; Trivedi, S; Ukropec, J; Usmani, SZ; White, D1
Abu Zaanona, MI; Patel, P1
Bishop, MR; Cohen, KS; Godfrey, JK; Karmali, R; Karrison, T; Kline, JP; Nabhan, C; Rapoport, AP; Smith, SM; Stadler, WM; Venugopal, P1
Auclair, D; Bahlis, NJ; Barwick, BG; Boise, LH; Dhodapkar, MV; Gupta, VA; Hofmeister, CC; Jaye, DL; Kaufman, JL; Keats, JJ; Lonial, S; Neri, P; Nooka, AK; Vertino, PM1
Fujinami, H; Iida, S; Ishida, T; Ito, A; Kinoshita, S; Komatsu, H; Kusumoto, S; Marumo, Y; Masaki, A; Narita, T; Oshima, Y; Ri, M; Sasaki, H; Tachita, T; Totani, H; Yoshida, T1
Rajkumar, SV1
Skarbnik, AP; Smith, MR1
Arakaki, H; Uchihara, JN1
Aoyama, Y; Furukawa, Y; Harada, N; Kumura, T; Manabe, M; Mugitani, A; Ohta, T; Okita, J; Tarakuwa, T1
Anderson, KC; Bianchi, G; Richardson, PG1
Vincent Rajkumar, S1
Buadi, FK; Dingli, D; Dispenzieri, A; Gertz, MA; Go, RS; Hayman, SR; Hwa, YL; Kapoor, P; Kaufman, GP; Kumar, SK; Kyle, RA; Lacy, MQ; Lust, JA; Rajkumar, SV; Russell, S1
Ando, T; Kimura, S; Kizuka, H; Kojima, K; Kubota, Y; Kusaba, K; Nishioka, A; Sano, H; Shindo, T; Ureshino, H1
Palumbo, A; Rajkumar, SV1
Kulharya, A; Shah, R; Ustun, C; Yuan, J1
Goldschmidt, H; Hielscher, T; Hillengass, J; Ho, AD; Hose, D; Jauch, A; Klein, U; Neben, K; Raab, MS; Seckinger, A1
Locke, FL; Morgan, GJ1
He, Y; Li, W; Li, X; Liu, F; Liu, X; You, Y; Zhang, M; Zheng, J; Zou, P1

Reviews

6 review(s) available for lenalidomide and Chromosomal Translocation

ArticleYear
Therapies for mantle cell lymphoma: current challenges and a brighter future.
    Discovery medicine, 2013, Volume: 15, Issue:82

    Topics: Antibodies; Antineoplastic Agents; Clinical Trials as Topic; Combined Modality Therapy; Cyclin D1; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Lenalidomide; Lymphoma, Mantle-Cell; Recurrence; Thalidomide; TOR Serine-Threonine Kinases; Translocation, Genetic; Treatment Outcome

2013
der(5;17)(p10;q10) is a recurrent but rare whole-arm translocation in patients with hematological neoplasms: a report of three cases.
    Acta haematologica, 2014, Volume: 132, Issue:2

    Topics: Aged; Aged, 80 and over; Anemia, Refractory, with Excess of Blasts; Aneuploidy; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Cell Transformation, Neoplastic; Chromosome Aberrations; Chromosome Banding; Chromosomes, Human, Pair 17; Chromosomes, Human, Pair 5; Contraindications; Fatal Outcome; Female; Hematologic Neoplasms; Humans; Karyotype; Lenalidomide; Leukemia, Myelomonocytic, Chronic; Lymphoma, T-Cell, Peripheral; Male; Megakaryocytes; Myelodysplastic Syndromes; Neoplasms, Second Primary; Recurrence; Remission Induction; Thalidomide; Translocation, Genetic

2014
Multiple myeloma: 2014 Update on diagnosis, risk-stratification, and management.
    American journal of hematology, 2014, Volume: 89, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Chromosomes, Human; Cyclophosphamide; Dexamethasone; Female; Humans; Lenalidomide; Male; Multiple Myeloma; Practice Guidelines as Topic; Pyrazines; Risk Assessment; Thalidomide; Translocation, Genetic

2014
5q- syndrome-like features as the first manifestation of myelodysplastic syndrome in a patient with an unbalanced whole-arm translocation der(5;19)(p10;q10).
    International journal of hematology, 2017, Volume: 105, Issue:5

    Topics: Anemia, Macrocytic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Carboplatin; Chromosome Aberrations; Chromosome Deletion; Chromosomes, Human, Pair 19; Chromosomes, Human, Pair 5; Fatal Outcome; Female; Humans; Lenalidomide; Leukemia, Myeloid, Acute; Middle Aged; Myelodysplastic Syndromes; Thalidomide; Translocation, Genetic

2017
Treatment of newly diagnosed myeloma.
    Leukemia, 2009, Volume: 23, Issue:3

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Chromosome Deletion; Clinical Trials as Topic; Combined Modality Therapy; Hematopoietic Stem Cell Transplantation; Humans; Immunologic Factors; Lenalidomide; Middle Aged; Multiple Myeloma; Myeloma Proteins; Prognosis; Pyrazines; Risk; Thalidomide; Translocation, Genetic; Transplantation Conditioning

2009
What is the evidence for the use of bisphosphonate therapy in newly diagnosed multiple myeloma patients lacking bone disease?
    Hematology. American Society of Hematology. Education Program, 2012, Volume: 2012

    Topics: Bone Diseases; Boronic Acids; Bortezomib; Dexamethasone; Diphosphonates; Fatigue; Fractures, Bone; Humans; Imidazoles; In Situ Hybridization, Fluorescence; Lenalidomide; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Myeloma; Proteinuria; Pyrazines; Randomized Controlled Trials as Topic; Thalidomide; Time Factors; Translocation, Genetic; Treatment Outcome; Zoledronic Acid

2012

Trials

2 trial(s) available for lenalidomide and Chromosomal Translocation

ArticleYear
Daratumumab, lenalidomide, and dexamethasone in relapsed/refractory myeloma: a cytogenetic subgroup analysis of POLLUX.
    Blood cancer journal, 2020, 11-03, Volume: 10, Issue:11

    Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Chromosome Deletion; Chromosomes, Human; Cytogenetic Analysis; Dexamethasone; Disease-Free Survival; Humans; Lenalidomide; Multiple Myeloma; Recurrence; Survival Rate; Translocation, Genetic

2020
Phase 1 study of lenalidomide plus dose-adjusted EPOCH-R in patients with aggressive B-cell lymphomas with deregulated MYC and BCL2.
    Cancer, 2019, 06-01, Volume: 125, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Feasibility Studies; Female; Humans; Lenalidomide; Lymphoma, Large B-Cell, Diffuse; Maintenance Chemotherapy; Male; Maximum Tolerated Dose; Middle Aged; Prednisone; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Rituximab; Translocation, Genetic; Treatment Outcome; Vincristine

2019

Other Studies

12 other study(ies) available for lenalidomide and Chromosomal Translocation

ArticleYear
KRD vs. VRD as induction before autologous hematopoietic progenitor cell transplantation for high-risk multiple myeloma.
    Bone marrow transplantation, 2022, Volume: 57, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bortezomib; Chromosome Aberrations; Dexamethasone; Hematopoietic Stem Cell Transplantation; Humans; Lenalidomide; Multiple Myeloma; Oligopeptides; Retrospective Studies; Translocation, Genetic; Transplantation, Autologous

2022
Autologous Stem Cell Transplantation for Patients with Multiple Myeloma with Translocation (4;14): The MD Anderson Cancer Center Experience.
    Transplantation and cellular therapy, 2023, Volume: 29, Issue:4

    Topics: Chromosome Aberrations; Female; Hematopoietic Stem Cell Transplantation; Humans; In Situ Hybridization, Fluorescence; Lenalidomide; Male; Multiple Myeloma; Retrospective Studies; Translocation, Genetic; Transplantation, Autologous

2023
Plasma cell leukaemia with t(11;14) not responsive to venetoclax.
    BMJ case reports, 2021, Jan-25, Volume: 14, Issue:1

    Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Dexamethasone; Hematopoietic Stem Cell Transplantation; Humans; In Situ Hybridization, Fluorescence; Lenalidomide; Leukemia, Plasma Cell; Male; Multiple Myeloma; Neoplasm Recurrence, Local; Oligopeptides; Oncogene Proteins, Fusion; Sulfonamides; Translocation, Genetic; Transplantation, Autologous; Treatment Failure

2021
Multiple myeloma immunoglobulin lambda translocations portend poor prognosis.
    Nature communications, 2019, 04-23, Volume: 10, Issue:1

    Topics: Antineoplastic Agents; DNA Copy Number Variations; Drug Resistance, Neoplasm; Enhancer Elements, Genetic; Gene Expression Regulation, Neoplastic; Genetic Loci; Genome, Human; Humans; Ikaros Transcription Factor; Immunoglobulin lambda-Chains; Immunologic Factors; Lenalidomide; Multiple Myeloma; Myeloma Proteins; Plasma Cells; Prognosis; Protein Binding; Proto-Oncogene Proteins c-myc; Recurrence; Survival Analysis; Thalidomide; Translocation, Genetic; Whole Genome Sequencing

2019
Impact of chromosomal abnormalities on the efficacy of lenalidomide plus dexamethasone treatment in patients with relapsed/refractory multiple myeloma.
    International journal of hematology, 2019, Volume: 110, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aneuploidy; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosome Banding; Combined Modality Therapy; Dexamethasone; Female; Hematopoietic Stem Cell Transplantation; Humans; In Situ Hybridization, Fluorescence; Kaplan-Meier Estimate; Lenalidomide; Male; Middle Aged; Multiple Myeloma; Progression-Free Survival; Recurrence; Retrospective Studies; Salvage Therapy; Translocation, Genetic; Transplantation, Autologous

2019
Multiple myeloma: 2013 update on diagnosis, risk-stratification, and management.
    American journal of hematology, 2013, Volume: 88, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Cyclophosphamide; Dexamethasone; Disease Management; Drug Administration Routes; Drug Administration Schedule; Hematopoietic Stem Cell Transplantation; Humans; Lenalidomide; Multiple Myeloma; Plasma Cells; Prognosis; Pyrazines; Recurrence; Risk; Thalidomide; Translocation, Genetic; Transplantation, Autologous

2013
[The appearance of t(9;22)(q34;q11.2) in BJP-λ type multiple myeloma during maintenance therapy including lenalidomide].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2013, Volume: 54, Issue:4

    Topics: Bence Jones Protein; Boronic Acids; Bortezomib; Chromosomes, Human, Pair 22; Chromosomes, Human, Pair 9; Humans; Lenalidomide; Male; Middle Aged; Multiple Myeloma; Pyrazines; Thalidomide; Translocation, Genetic

2013
Best treatment strategies in high-risk multiple myeloma: navigating a gray area.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014, Jul-10, Volume: 32, Issue:20

    Topics: Antineoplastic Combined Chemotherapy Protocols; Back Pain; Biopsy; Bone Density Conservation Agents; Bone Marrow; Boronic Acids; Bortezomib; Dexamethasone; Diphosphonates; Fatigue; Hematopoietic Stem Cell Transplantation; Humans; Imidazoles; Immunoglobulin G; Immunoglobulin lambda-Chains; Lenalidomide; Male; Middle Aged; Multiple Myeloma; Neoplasm Staging; Pyrazines; Referral and Consultation; Thalidomide; Translocation, Genetic; Transplantation, Autologous; Zoledronic Acid

2014
Impact of cytogenetic classification on outcomes following early high-dose therapy in multiple myeloma.
    Leukemia, 2016, Volume: 30, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bortezomib; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 14; Chromosomes, Human, Pair 17; Cytogenetic Analysis; Dexamethasone; Hematopoietic Stem Cell Transplantation; Humans; In Situ Hybridization, Fluorescence; Induction Chemotherapy; Lenalidomide; Male; Melphalan; Middle Aged; Multiple Myeloma; Prognosis; Remission Induction; Retrospective Studies; Survival Analysis; Thalidomide; Translocation, Genetic; Transplantation, Autologous; Treatment Outcome

2016
Near-tetraploidy clone can evolve from a hyperdiploidy clone and cause resistance to lenalidomide and bortezomib in a multiple myeloma patient.
    Leukemia research, 2010, Volume: 34, Issue:7

    Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Chromosome Deletion; Chromosomes, Human, Pair 13; Chromosomes, Human, Pair 14; Chromosomes, Human, Pair 8; Clone Cells; Combined Modality Therapy; Dexamethasone; Drug Resistance, Neoplasm; Female; Humans; Karyotyping; Lenalidomide; Middle Aged; Multiple Myeloma; Neoplastic Stem Cells; Peripheral Blood Stem Cell Transplantation; Polyploidy; Protease Inhibitors; Pyrazines; Thalidomide; Translocation, Genetic; Transplantation, Autologous

2010
Chromosomal aberrations +1q21 and del(17p13) predict survival in patients with recurrent multiple myeloma treated with lenalidomide and dexamethasone.
    Cancer, 2011, May-15, Volume: 117, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosome Deletion; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 14; Chromosomes, Human, Pair 17; Dexamethasone; Female; Humans; Lenalidomide; Male; Middle Aged; Multiple Myeloma; Prognosis; Recurrence; Thalidomide; Translocation, Genetic

2011
Response to lenalidomide of a patient with t(2;3)(p23;q29) and JAK2 non-mutated refractory anemia with ring sideroblasts and thrombocytosis.
    Leukemia & lymphoma, 2013, Volume: 54, Issue:7

    Topics: Adult; Anemia, Refractory; Bone Marrow; Chromosomes, Human, Pair 2; Chromosomes, Human, Pair 3; Female; Humans; Janus Kinase 2; Karyotype; Lenalidomide; Thalidomide; Thrombocytosis; Translocation, Genetic; Treatment Outcome

2013