leflunomide has been researched along with Weight Reduction in 4 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
| Excerpt | Relevance | Reference |
|---|---|---|
| " She was known to have type 1 diabetes mellitus, previous Hashimoto's thyroiditis, rheumatoid arthritis treated with leflunomide and drug- treated arterial hypertension." | 7.74 | [Persistent diarrhea and loss of weight during therapy with leflunomide]. ( Berges, W; Donner, P; Gugenberger, C; Naami, A, 2008) |
| "Diarrhoea and weight loss are frequently reported adverse events in rheumatoid arthritis (RA) patients receiving the disease-modifying antirheumatic drug (DMARD) leflunomide." | 7.73 | Debilitating diarrhoea and weight loss due to colitis in two RA patients treated with leflunomide. ( Vandooren, AK; Verschueren, P; Westhovens, R, 2005) |
| "To determine the frequency of weight loss in patients treated with leflunomide for rheumatoid arthritis at an arthritis referral center." | 7.71 | Leflunomide-associated weight loss in rheumatoid arthritis. ( Coblyn, JS; Helfgott, S; Shadick, N, 2001) |
| " She was known to have type 1 diabetes mellitus, previous Hashimoto's thyroiditis, rheumatoid arthritis treated with leflunomide and drug- treated arterial hypertension." | 3.74 | [Persistent diarrhea and loss of weight during therapy with leflunomide]. ( Berges, W; Donner, P; Gugenberger, C; Naami, A, 2008) |
| "Diarrhoea and weight loss are frequently reported adverse events in rheumatoid arthritis (RA) patients receiving the disease-modifying antirheumatic drug (DMARD) leflunomide." | 3.73 | Debilitating diarrhoea and weight loss due to colitis in two RA patients treated with leflunomide. ( Vandooren, AK; Verschueren, P; Westhovens, R, 2005) |
| "To determine the frequency of weight loss in patients treated with leflunomide for rheumatoid arthritis at an arthritis referral center." | 3.71 | Leflunomide-associated weight loss in rheumatoid arthritis. ( Coblyn, JS; Helfgott, S; Shadick, N, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gugenberger, C | 1 |
| Donner, P | 1 |
| Naami, A | 1 |
| Berges, W | 1 |
| Verschueren, P | 1 |
| Vandooren, AK | 1 |
| Westhovens, R | 1 |
| Kremer, AE | 1 |
| Budenhofer, U | 1 |
| Beuers, U | 1 |
| Rust, C | 1 |
| Coblyn, JS | 1 |
| Shadick, N | 1 |
| Helfgott, S | 1 |
4 other studies available for leflunomide and Weight Reduction
| Article | Year |
|---|---|
[Persistent diarrhea and loss of weight during therapy with leflunomide].
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Colitis, Lymphocytic; Diabetes Mellitus, Type 1; Diarrh | 2008 |
Debilitating diarrhoea and weight loss due to colitis in two RA patients treated with leflunomide.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Biopsy; Colitis; Colon; Colon | 2005 |
[A 47-year-old dog breeder with chronic polyarthritis, weight loss and high fever].
Topics: Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthrit | 2008 |
Leflunomide-associated weight loss in rheumatoid arthritis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Female; Humans; Isoxazoles; Le | 2001 |