Page last updated: 2024-10-30

leflunomide and Weight Reduction

leflunomide has been researched along with Weight Reduction in 4 studies

Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.

Research Excerpts

ExcerptRelevanceReference
" She was known to have type 1 diabetes mellitus, previous Hashimoto's thyroiditis, rheumatoid arthritis treated with leflunomide and drug- treated arterial hypertension."7.74[Persistent diarrhea and loss of weight during therapy with leflunomide]. ( Berges, W; Donner, P; Gugenberger, C; Naami, A, 2008)
"Diarrhoea and weight loss are frequently reported adverse events in rheumatoid arthritis (RA) patients receiving the disease-modifying antirheumatic drug (DMARD) leflunomide."7.73Debilitating diarrhoea and weight loss due to colitis in two RA patients treated with leflunomide. ( Vandooren, AK; Verschueren, P; Westhovens, R, 2005)
"To determine the frequency of weight loss in patients treated with leflunomide for rheumatoid arthritis at an arthritis referral center."7.71Leflunomide-associated weight loss in rheumatoid arthritis. ( Coblyn, JS; Helfgott, S; Shadick, N, 2001)
" She was known to have type 1 diabetes mellitus, previous Hashimoto's thyroiditis, rheumatoid arthritis treated with leflunomide and drug- treated arterial hypertension."3.74[Persistent diarrhea and loss of weight during therapy with leflunomide]. ( Berges, W; Donner, P; Gugenberger, C; Naami, A, 2008)
"Diarrhoea and weight loss are frequently reported adverse events in rheumatoid arthritis (RA) patients receiving the disease-modifying antirheumatic drug (DMARD) leflunomide."3.73Debilitating diarrhoea and weight loss due to colitis in two RA patients treated with leflunomide. ( Vandooren, AK; Verschueren, P; Westhovens, R, 2005)
"To determine the frequency of weight loss in patients treated with leflunomide for rheumatoid arthritis at an arthritis referral center."3.71Leflunomide-associated weight loss in rheumatoid arthritis. ( Coblyn, JS; Helfgott, S; Shadick, N, 2001)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gugenberger, C1
Donner, P1
Naami, A1
Berges, W1
Verschueren, P1
Vandooren, AK1
Westhovens, R1
Kremer, AE1
Budenhofer, U1
Beuers, U1
Rust, C1
Coblyn, JS1
Shadick, N1
Helfgott, S1

Other Studies

4 other studies available for leflunomide and Weight Reduction

ArticleYear
[Persistent diarrhea and loss of weight during therapy with leflunomide].
    Deutsche medizinische Wochenschrift (1946), 2008, Volume: 133, Issue:34-35

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Colitis, Lymphocytic; Diabetes Mellitus, Type 1; Diarrh

2008
Debilitating diarrhoea and weight loss due to colitis in two RA patients treated with leflunomide.
    Clinical rheumatology, 2005, Volume: 24, Issue:1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Biopsy; Colitis; Colon; Colon

2005
[A 47-year-old dog breeder with chronic polyarthritis, weight loss and high fever].
    Zeitschrift fur Gastroenterologie, 2008, Volume: 46, Issue:5

    Topics: Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthrit

2008
Leflunomide-associated weight loss in rheumatoid arthritis.
    Arthritis and rheumatism, 2001, Volume: 44, Issue:5

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Female; Humans; Isoxazoles; Le

2001