Page last updated: 2024-10-30

leflunomide and Viremia

leflunomide has been researched along with Viremia in 12 studies

Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.

Viremia: The presence of viruses in the blood.

Research Excerpts

ExcerptRelevanceReference
"To describe leflunomide use in the treatment of drug resistant cytomegalovirus retinitis."7.85Utility of Leflunomide in the Treatment of Drug Resistant Cytomegalovirus Retinitis. ( Goldstein, DA; Jumroendararasame, C; Minkus, CL; Pursell, K; Rifkin, LM, 2017)
"TTV DNA load was quantified by PCR in a cross-sectional sample of 79 patients with chronic arthritis on biologic therapy (abatacept, infliximab, rituximab or tocilizumab), 31 patients treated with conventional DMARDs (methotrexate and/or leflunomide), and 54 healthy individuals."3.96Torque teno virus viremia in patients with chronic arthritis: Influence of biologic therapies. ( Aguado, JM; Albert, E; Fernández-Ruiz, M; González-Álvaro, I; Martín-López, M; Navarro, D; Pablos, JL; Rodríguez, E, 2020)
"To describe leflunomide use in the treatment of drug resistant cytomegalovirus retinitis."3.85Utility of Leflunomide in the Treatment of Drug Resistant Cytomegalovirus Retinitis. ( Goldstein, DA; Jumroendararasame, C; Minkus, CL; Pursell, K; Rifkin, LM, 2017)
" Patients with significant viremia and/or biopsy-proven BKPVAN were treated with immunosuppression reduction and leflunomide."3.85Stabilization of renal function after the first year of follow-up in kidney transplant recipients treated for significant BK polyomavirus infection or BK polyomavirus-associated nephropathy. ( Bodson-Clermont, P; Cardinal, H; Fortin, MC; Girardin, C; Hébert, MJ; Lévesque, R; Pâquet, MR; Renoult, E; Simard-Meilleur, MC; St-Louis, G, 2017)
"This analysis demonstrates for the first time that, used in a stepwise fashion, ciprofloxacin and leflunomide are effective and safe treatments for BK viremia in PRTR."3.80A novel treatment regimen for BK viremia. ( Cheam, H; Ettenger, RB; Malekzadeh, MH; Tsai, EW; Zaman, RA, 2014)
"BK viremia and nephritis are increasing problems in renal transplant recipients."2.43BK virus nephritis after renal transplantation. ( Hariharan, S, 2006)
"Treatment with leflunomide was started after a mean of 1."1.51Clinical utility of leflunomide for BK polyomavirus associated nephropathy in kidney transplant recipients: A multicenter retrospective study. ( Bouvier, N; Caillard, S; Conrad, A; Duquennoy, S; Fafi-Kremer, S; Hurault De Ligny, B; Keller, N; Morelon, E; Moulin, B, 2019)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (8.33)29.6817
2010's9 (75.00)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Kurašová, E1
Štěpán, J1
Krejčí, K1
Mrázek, F1
Sauer, P1
Janečková, J1
Tichý, T1
Keller, N1
Duquennoy, S1
Conrad, A1
Fafi-Kremer, S1
Morelon, E1
Bouvier, N1
Moulin, B1
Hurault De Ligny, B1
Caillard, S1
Martín-López, M1
Albert, E1
Fernández-Ruiz, M1
González-Álvaro, I1
Rodríguez, E1
Aguado, JM1
Navarro, D1
Pablos, JL1
Dunn, JH1
Weinberg, A1
Chan, LK1
Mandava, N1
Levi, ME1
Olson, JL1
Zaman, RA1
Ettenger, RB1
Cheam, H1
Malekzadeh, MH1
Tsai, EW1
Gagneux-Brunon, A1
Pillet, S1
Laurent, B1
Mariat, C1
Michalet, M1
Lucht, F1
Botelho-Nevers, E1
Rifkin, LM1
Minkus, CL1
Pursell, K1
Jumroendararasame, C1
Goldstein, DA1
Ambrose, T1
Sharkey, LM1
Louis-Auguste, J1
Rutter, CS1
Duncan, S1
English, S1
Gkrania-Klotsas, E1
Carmichael, A1
Woodward, JM1
Russell, N1
Massey, D1
Butler, A1
Middleton, S1
Yang, D1
Keys, B1
J Conti, D1
Foulke, L1
Stellrecht, K1
Cook, L1
Lopez-Soler, RI1
Simard-Meilleur, MC1
Bodson-Clermont, P1
St-Louis, G1
Pâquet, MR1
Girardin, C1
Fortin, MC1
Cardinal, H1
Hébert, MJ1
Lévesque, R1
Renoult, E1
Butts, RJ1
Uber, WE1
Savage, AJ1
Hariharan, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
BK Viremia and BK Virus Nephropathy Post Kidney Transplant Comparison of New Practices With Traditional Approach: A Combined Retrospective Chart Review and Prospective Observational Study[NCT02758288]0 participants (Actual)Observational2015-09-30Withdrawn
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for leflunomide and Viremia

ArticleYear
JC polyomavirus nephropathy, a rare cause of transplant dysfunction: Case report and review of literature.
    Transplant infectious disease : an official journal of the Transplantation Society, 2017, Volume: 19, Issue:2

    Topics: Biopsy; BK Virus; Creatinine; Graft Rejection; Humans; Immunoglobulins, Intravenous; Immunosuppressi

2017
BK virus nephritis after renal transplantation.
    Kidney international, 2006, Volume: 69, Issue:4

    Topics: Antibodies, Viral; Antiviral Agents; BK Virus; Cidofovir; Cytosine; DNA, Viral; Graft Survival; Huma

2006

Other Studies

10 other studies available for leflunomide and Viremia

ArticleYear
Current Status, Prevention and Treatment of BK Virus Nephropathy.
    Acta medica (Hradec Kralove), 2022, Volume: 65, Issue:4

    Topics: BK Virus; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Leflunomide; Po

2022
Clinical utility of leflunomide for BK polyomavirus associated nephropathy in kidney transplant recipients: A multicenter retrospective study.
    Transplant infectious disease : an official journal of the Transplantation Society, 2019, Volume: 21, Issue:2

    Topics: Adult; Aged; Female; Graft Rejection; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kid

2019
Torque teno virus viremia in patients with chronic arthritis: Influence of biologic therapies.
    Seminars in arthritis and rheumatism, 2020, Volume: 50, Issue:1

    Topics: Abatacept; Adult; Aged; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis; Biologic

2020
Long-term suppression of multidrug-resistant cytomegalovirus retinitis with systemically administered leflunomide.
    JAMA ophthalmology, 2013, Volume: 131, Issue:7

    Topics: Administration, Oral; Adult; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Retinitis; Drug Resi

2013
A novel treatment regimen for BK viremia.
    Transplantation, 2014, Jun-15, Volume: 97, Issue:11

    Topics: Adolescent; BK Virus; Child; Ciprofloxacin; Female; Fluoroquinolones; Glomerular Filtration Rate; Hu

2014
A case of BK virus nephropathy in a stem cell transplant recipient: a rare or under-recognized cause for Acute Kidney injury.
    Medecine et maladies infectieuses, 2015, Volume: 45, Issue:8

    Topics: Acute Kidney Injury; Anti-Bacterial Agents; BK Virus; Ciprofloxacin; Cord Blood Stem Cell Transplant

2015
Utility of Leflunomide in the Treatment of Drug Resistant Cytomegalovirus Retinitis.
    Ocular immunology and inflammation, 2017, Volume: 25, Issue:1

    Topics: Administration, Oral; Aged; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Retinitis; Drug Resis

2017
Cytomegalovirus Infection and Rates of Antiviral Resistance Following Intestinal and Multivisceral Transplantation.
    Transplantation proceedings, 2016, Volume: 48, Issue:2

    Topics: Adult; Aged; Antiviral Agents; Cytomegalovirus Infections; Drug Resistance, Viral; Female; Foscarnet

2016
Stabilization of renal function after the first year of follow-up in kidney transplant recipients treated for significant BK polyomavirus infection or BK polyomavirus-associated nephropathy.
    Transplant infectious disease : an official journal of the Transplantation Society, 2017, Volume: 19, Issue:3

    Topics: Adult; Allografts; Antiviral Agents; Biopsy; BK Virus; DNA, Viral; Female; Follow-Up Studies; Glomer

2017
Treatment of BK viremia in a pediatric heart transplant recipient.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2012, Volume: 31, Issue:5

    Topics: Antiviral Agents; BK Virus; Child; Female; Graft Rejection; Heart Transplantation; Humans; Immunosup

2012