leflunomide has been researched along with Urinary Bladder Neoplasms in 2 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Urinary Bladder Neoplasms: Tumors or cancer of the URINARY BLADDER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Leflunomide markedly inhibited the growth of both bladder cancer cell lines and induced apoptosis and cell cycle arrest in S phase." | 7.96 | Leflunomide Inhibits Proliferation and Induces Apoptosis via Suppressing Autophagy and PI3K/Akt Signaling Pathway in Human Bladder Cancer Cells. ( Cheng, L; Huang, H; Lin, J; Wang, H; Wang, Z; Zhuo, D, 2020) |
| "Angiogenesis plays an important role in bladder cancer (BCa)." | 5.48 | Inhibition of angiogenesis by leflunomide via targeting the soluble ephrin-A1/EphA2 system in bladder cancer. ( Chu, M; Zhang, C, 2018) |
| "Leflunomide markedly inhibited the growth of both bladder cancer cell lines and induced apoptosis and cell cycle arrest in S phase." | 3.96 | Leflunomide Inhibits Proliferation and Induces Apoptosis via Suppressing Autophagy and PI3K/Akt Signaling Pathway in Human Bladder Cancer Cells. ( Cheng, L; Huang, H; Lin, J; Wang, H; Wang, Z; Zhuo, D, 2020) |
| "Angiogenesis plays an important role in bladder cancer (BCa)." | 1.48 | Inhibition of angiogenesis by leflunomide via targeting the soluble ephrin-A1/EphA2 system in bladder cancer. ( Chu, M; Zhang, C, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, L | 1 |
| Wang, H | 1 |
| Wang, Z | 1 |
| Huang, H | 1 |
| Zhuo, D | 1 |
| Lin, J | 1 |
| Chu, M | 1 |
| Zhang, C | 1 |
2 other studies available for leflunomide and Urinary Bladder Neoplasms
| Article | Year |
|---|---|
Leflunomide Inhibits Proliferation and Induces Apoptosis via Suppressing Autophagy and PI3K/Akt Signaling Pathway in Human Bladder Cancer Cells.
Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Cell Survival; Dose-Response Relationship, Dru | 2020 |
Inhibition of angiogenesis by leflunomide via targeting the soluble ephrin-A1/EphA2 system in bladder cancer.
Topics: Angiogenesis Inhibitors; Animals; Cell Line, Tumor; Coculture Techniques; Disease Models, Animal; En | 2018 |