leflunomide has been researched along with Thrombocytopenia in 3 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Thrombocytopenia: A subnormal level of BLOOD PLATELETS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To estimate the incidence of pancytopenia in patients taking leflunomide with or without methotrexate in Australia." | 7.74 | The incidence of pancytopenia in patients taking leflunomide alone or with methotrexate. ( Calcino, LJ; Hill, RL; McEwen, J; Purcell, PM; Riley, CG, 2007) |
| "To estimate the incidence of pancytopenia in patients taking leflunomide with or without methotrexate in Australia." | 3.74 | The incidence of pancytopenia in patients taking leflunomide alone or with methotrexate. ( Calcino, LJ; Hill, RL; McEwen, J; Purcell, PM; Riley, CG, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Nakafero, G | 1 |
| Grainge, MJ | 1 |
| Card, T | 1 |
| Mallen, CD | 1 |
| Zhang, W | 1 |
| Doherty, M | 1 |
| Taal, MW | 1 |
| Aithal, GP | 1 |
| Abhishek, A | 1 |
| Lu, MC | 1 |
| Yu, CL | 1 |
| Yin, WY | 1 |
| Tung, CH | 1 |
| Huang, KY | 1 |
| Liu, SQ | 1 |
| Lai, NS | 1 |
| McEwen, J | 1 |
| Purcell, PM | 1 |
| Hill, RL | 1 |
| Calcino, LJ | 1 |
| Riley, CG | 1 |
3 other studies available for leflunomide and Thrombocytopenia
| Article | Year |
|---|---|
What is the incidence of methotrexate or leflunomide discontinuation related to cytopenia, liver enzyme elevation or kidney function decline?
Topics: Alanine Transaminase; Aspartate Aminotransferases; Biomarkers; Female; Humans; Immunosuppressive Age | 2021 |
Increased prevalence of polyomavirus BK viruria that correlates with thrombocytopenia in patients with systemic lupus erythematosus on intensive immunosuppressive therapy.
Topics: Adult; Antiviral Agents; BK Virus; Female; Humans; Immunosuppression Therapy; Isoxazoles; Leflunomid | 2009 |
The incidence of pancytopenia in patients taking leflunomide alone or with methotrexate.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Age Factors; Aged; Aged, 80 and over; An | 2007 |