leflunomide has been researched along with Shock, Septic in 2 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Shock, Septic: Sepsis associated with HYPOTENSION or hypoperfusion despite adequate fluid resuscitation. Perfusion abnormalities may include but are not limited to LACTIC ACIDOSIS; OLIGURIA; or acute alteration in mental status.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Leflunomide is a DMARD that has a prolonged half-life due to enterohepatic recirculation." | 2.53 | Use of a Cholestyramine Washout in a Patient With Septic Shock on Leflunomide Therapy: A Case Report and Review of the Literature. ( Fraser, R; Kiser, TH; Kurche, J; Lara, A; Laub, M; Reynolds, PM, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Laub, M | 1 |
| Fraser, R | 1 |
| Kurche, J | 1 |
| Lara, A | 1 |
| Kiser, TH | 1 |
| Reynolds, PM | 1 |
| Chikkamuniyappa, S | 1 |
1 review available for leflunomide and Shock, Septic
| Article | Year |
|---|---|
Use of a Cholestyramine Washout in a Patient With Septic Shock on Leflunomide Therapy: A Case Report and Review of the Literature.
Topics: Aged; Antirheumatic Agents; Cholestyramine Resin; Female; Humans; Isoxazoles; Leflunomide; Prosthesi | 2016 |
1 other study available for leflunomide and Shock, Septic
| Article | Year |
|---|---|
Streptococcal toxic shock syndrome and sepsis manifesting in a patient with chronic rheumatoid arthritis.
Topics: Accidental Falls; Adrenal Cortex Hormones; Aged; Amputation, Surgical; Anti-Bacterial Agents; Antirh | 2004 |