leflunomide has been researched along with Shingles in 5 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare infectious risk between leflunomide versus TNF inhibitors (TNFi), and between tacrolimus versus TNFi among rheumatoid arthritis (RA) patients receiving methotrexate (MTX)." | 8.12 | Infectious risk of add-on leflunomide or tacrolimus versus TNF inhibitors among patients with rheumatoid arthritis receiving background methotrexate: A population-based cohort study. ( Ha, YJ; Kang, EH; Lee, EB; Lee, JH; Lee, YJ; Shin, A, 2022) |
| "Patients with rheumatoid arthritis (RA) are at increased risk of herpes zoster (HZ), and the risk appears to be increased in patients treated with tofacitinib." | 7.85 | Herpes Zoster and Tofacitinib: Clinical Outcomes and the Risk of Concomitant Therapy. ( Bananis, E; Chen, C; Curtis, JR; Fan, H; Hirose, T; Lindsey, S; Mendelsohn, AM; Nduaka, CI; Tanaka, Y; Valdez, H; Wang, L; Winthrop, KL; Yamaoka, K, 2017) |
| "To compare infectious risk between leflunomide versus TNF inhibitors (TNFi), and between tacrolimus versus TNFi among rheumatoid arthritis (RA) patients receiving methotrexate (MTX)." | 4.12 | Infectious risk of add-on leflunomide or tacrolimus versus TNF inhibitors among patients with rheumatoid arthritis receiving background methotrexate: A population-based cohort study. ( Ha, YJ; Kang, EH; Lee, EB; Lee, JH; Lee, YJ; Shin, A, 2022) |
| "Patients with rheumatoid arthritis (RA) are at increased risk of herpes zoster (HZ), and the risk appears to be increased in patients treated with tofacitinib." | 3.85 | Herpes Zoster and Tofacitinib: Clinical Outcomes and the Risk of Concomitant Therapy. ( Bananis, E; Chen, C; Curtis, JR; Fan, H; Hirose, T; Lindsey, S; Mendelsohn, AM; Nduaka, CI; Tanaka, Y; Valdez, H; Wang, L; Winthrop, KL; Yamaoka, K, 2017) |
| "Of these 22 patients, 16 had varicella and 6 had herpes zoster." | 1.43 | Clinical course and therapeutic approach to varicella zoster virus infection in children with rheumatic autoimmune diseases under immunosuppression. ( Aeschlimann, F; Baer, W; Berthet, G; Cannizzaro, E; Heininger, U; Hofer, M; Kaiser, D; Leuvenink, R; Schroeder, S; Woerner, A, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shin, A | 1 |
| Lee, JH | 1 |
| Ha, YJ | 1 |
| Lee, YJ | 1 |
| Lee, EB | 1 |
| Kang, EH | 1 |
| Winthrop, KL | 1 |
| Curtis, JR | 1 |
| Lindsey, S | 1 |
| Tanaka, Y | 1 |
| Yamaoka, K | 1 |
| Valdez, H | 1 |
| Hirose, T | 1 |
| Nduaka, CI | 1 |
| Wang, L | 1 |
| Mendelsohn, AM | 1 |
| Fan, H | 1 |
| Chen, C | 1 |
| Bananis, E | 1 |
| Zisman, D | 1 |
| Bitterman, H | 1 |
| Shalom, G | 1 |
| Feldhamer, I | 1 |
| Comanesther, D | 1 |
| Batat, E | 1 |
| Greenberg-Dotan, S | 1 |
| Cohen, S | 1 |
| Cohen, AD | 1 |
| Leuvenink, R | 1 |
| Aeschlimann, F | 1 |
| Baer, W | 1 |
| Berthet, G | 1 |
| Cannizzaro, E | 1 |
| Hofer, M | 1 |
| Kaiser, D | 1 |
| Schroeder, S | 1 |
| Heininger, U | 1 |
| Woerner, A | 1 |
| Liao, TL | 1 |
| Chen, YM | 1 |
| Liu, HJ | 1 |
| Chen, DY | 1 |
5 other studies available for leflunomide and Shingles
| Article | Year |
|---|---|
Infectious risk of add-on leflunomide or tacrolimus versus TNF inhibitors among patients with rheumatoid arthritis receiving background methotrexate: A population-based cohort study.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cohort Studies; Herpes Zoster; Humans; Infections; Lefl | 2022 |
Herpes Zoster and Tofacitinib: Clinical Outcomes and the Risk of Concomitant Therapy.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Clinical Trials as Topic; Dat | 2017 |
Psoriatic arthritis treatment and the risk of herpes zoster.
Topics: Adalimumab; Adult; Aged; Antirheumatic Agents; Arthritis, Psoriatic; Azathioprine; Cyclosporine; Dru | 2016 |
Clinical course and therapeutic approach to varicella zoster virus infection in children with rheumatic autoimmune diseases under immunosuppression.
Topics: Acyclovir; Adolescent; Antirheumatic Agents; Antiviral Agents; Arthritis, Juvenile; Chickenpox; Chil | 2016 |
Risk and severity of herpes zoster in patients with rheumatoid arthritis receiving different immunosuppressive medications: a case-control study in Asia.
Topics: Abatacept; Adalimumab; Adrenal Cortex Hormones; Adult; Aged; Antibodies, Monoclonal; Antibodies, Mon | 2017 |