leflunomide has been researched along with Respiratory Syncytial Virus Infections in 4 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Respiratory Syncytial Virus Infections: Pneumovirus infections caused by the RESPIRATORY SYNCYTIAL VIRUSES. Humans and cattle are most affected but infections in goats and sheep have been reported.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dunn, MC | 1 |
| Knight, DA | 1 |
| Waldman, WJ | 1 |
| Davis, IC | 2 |
| Lazarowski, ER | 2 |
| Hickman-Davis, JM | 2 |
| Fortenberry, JA | 1 |
| Chen, FP | 2 |
| Zhao, X | 1 |
| Sorscher, E | 1 |
| Graves, LM | 1 |
| Sullender, WM | 2 |
| Matalon, S | 2 |
| Peebles, RS | 1 |
| Moore, ML | 1 |
4 other studies available for leflunomide and Respiratory Syncytial Virus Infections
| Article | Year |
|---|---|
Inhibition of respiratory syncytial virus in vitro and in vivo by the immunosuppressive agent leflunomide.
Topics: Animals; Antiviral Agents; Bronchi; Cell Line, Tumor; Cytopathogenic Effect, Viral; Dose-Response Re | 2011 |
Leflunomide prevents alveolar fluid clearance inhibition by respiratory syncytial virus.
Topics: Animals; Antiviral Agents; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Disease Progression | 2006 |
Post-infection A77-1726 blocks pathophysiologic sequelae of respiratory syncytial virus infection.
Topics: Administration, Intranasal; Airway Resistance; Aniline Compounds; Animals; Antiviral Agents; Broncho | 2007 |
A mechanistic advance in understanding RSV pathogenesis, but still a long way from therapy.
Topics: Aged; Airway Obstruction; Animals; Antibodies, Viral; Antiviral Agents; Cattle; Humans; Infant; Isox | 2007 |